Gracilinanus agilis (agile gracile opossum): 123251357
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Entry
123251357 CDS
T07702
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00260
Glycine, serine and threonine metabolism
gas00630
Glyoxylate and dicarboxylate metabolism
gas00670
One carbon pool by folate
gas01100
Metabolic pathways
gas01200
Carbon metabolism
gas01230
Biosynthesis of amino acids
gas01240
Biosynthesis of cofactors
gas01523
Antifolate resistance
gas04981
Folate transport and metabolism
Module
gas_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
123251357 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
123251357 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
123251357 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
123251357 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123251357 (SHMT2)
Enzymes [BR:
gas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
123251357 (SHMT2)
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GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
123251357
NCBI-ProteinID:
XP_044536540
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All DBs
Position
6:288756785..288765311
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AA seq
501 aa
AA seq
DB search
MLPFPLLRAFRRGSWLFQVALRAQHGEAAKAQAGETTRGWTGQESLSDSDPEMWELLQRE
KDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRA
LEAFDLDPARWGVNVQPYSGSPANLAAYTAVLQPHDRIMGLDLPDGGHLTHGYMSNVKRI
SATSIFFESMPYKLNPSTGLIDYEQLAITARLFRPRLIIAGTSAYARLIDYARMREVCDE
VKAHLLADMAHISGLVAAKVIPSPFDHADIVTTTTHKTLRGARSGLIFYRKGVQSVDPKT
GREILYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQVNTPMFREYSKQVLRNARAMAD
ALLQRGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGG
LRLGAPALTSRHFREDDFRQVVNFIDEGVQIGLDVKSRTGKLQDFKSFLLNDPETRQRLA
DLRQRVEAFARAFPMPGFEER
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgttaccctttcccttgctccgtgcattccggagaggcagctggctgttccaggtcgct
cttcgggcccagcatggggaggcagccaaggcccaggctggagagaccaccagaggctgg
acaggccaggaaagcctgtctgacagtgaccctgagatgtgggaactcctacaaagggag
aaggatagacagtgccggggcctagagctcattgcctcagagaacttctgtagccgagca
gccctggaggctttgggatcctgtctaaacaacaagtattcagagggctaccctggcaag
aggtattacggaggagccgaggtagtggatgagattgagctgttgtgccagcgacgtgcc
ctagaggcctttgaccttgaccctgcccgatggggagtcaatgtccagccatattcaggg
tccccggccaatctggctgcttatacagctgtcctgcagccccacgacaggatcatggga
ttggatctgcccgatggaggccatctcactcacggttatatgtccaatgtcaagcgaatc
tcagccacgtccatcttctttgaatctatgccctataaactcaacccttcaactggcctc
attgattacgagcagctggccatcactgcccggctgttccggccacgtctcatcattgcg
ggcaccagcgcctatgctcgtctcatcgattatgcccgcatgagggaggtgtgtgatgag
gtcaaagcccacctgctggctgacatggcgcacatcagtgggctggtagctgccaaagtc
atcccttcacccttcgaccatgcagacatcgtcacaaccaccacccacaagaccttgcgg
ggggccaggtcagggctcattttctatcgtaagggggtgcagtctgtggaccccaagacc
ggccgagagatcctctacacgtttgaggaccgaatcaactttgctgtgttcccttccctg
cagggggggccccataaccatgccattgccgctgtggcagtggccctcaagcaggtcaat
accccgatgttccgcgagtattccaagcaggtccttcgcaatgcccgggccatggctgac
gcgcttctccagaggggctattccctggtgtctggcggcaccgataaccacttggttctg
gtggacctacggcccaaagggctggacggagcgagggctgagcgtgtcctggaactcgtg
tctatcactgccaacaagaacacctgccccggggaccgcagcgccatcaccccagggggc
ctccgtctcggggccccggccttgacctcccgacactttcgagaagacgacttccgccaa
gtggtgaactttatcgacgagggtgttcagatcgggctggacgtgaagagccggacaggg
aagctccaagatttcaaatcattcctcctgaacgaccctgaaacaagacagcgcctggcg
gacctcaggcagcgggtggaagcctttgcccgggcctttcccatgccgggcttcgaggag
cgataa
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