Gasterosteus aculeatus (three-spined stickleback): 120828372
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Entry
120828372 CDS
T07457
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
gat
Gasterosteus aculeatus (three-spined stickleback)
Pathway
gat04217
Necroptosis
gat04620
Toll-like receptor signaling pathway
gat04621
NOD-like receptor signaling pathway
gat05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
gat00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
120828372 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
120828372 (tyk2)
04621 NOD-like receptor signaling pathway
120828372 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
120828372 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gat01001
]
120828372 (tyk2)
Enzymes [BR:
gat01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120828372 (tyk2)
Protein kinases [BR:
gat01001
]
Non-receptor tyrosine kinases
JAK family [OT]
120828372 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
Kinase-like
RIO1
ABC1
SH2
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
120828372
NCBI-ProteinID:
XP_040047854
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All DBs
Position
XI:14264203..14273918
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AA seq
1160 aa
AA seq
DB search
MSRRGRSKSSRSGAPAALREPPQAAGIHVYLFWSKEGERYLSHSAGRVTAEDLCICAAEA
AGITPLCHTLFALYNPHSRCWYSPNHEFSPDDSNLVLHFRMRFYFRNWHGLNEKEPTVSR
YAHRSGQGGSPLFEITSLEYLFFQAKYEFVNEMVQMEDVQSEEEGSRLKNESLGMAVLQL
SHQAMLTGCTLQDAADKVSFLHCIPRSFAKQISKDNFLTKLRIRRVFREFVRTFQQHTVD
KGRLGAQEIMYRYIATLEHLAPRFGSETFPVSQLELRDDGIESSSYSNSTRYEGAPEDDF
IGPATHEVLVSGTKGVRWRPVSEQKAQANTYLRNDYMKTKKQPSSQPSENTTDKWTSFCD
FREITHIAITGTNVCISTLDNRCLEVQMNSSQEARSFISLLDGYNRLTAFAHHYLCHEVA
PPRVVLSVANGLHGPMHDDFVLLKLRREAAEEGAFLVRWSALDYRGIILAVLNKNENGTK
PGHKQFRIQLKGPKFCLEGWDREFSSVKELAESLKTFVLKSGSDSFTVRKCCLPKHAELS
NLVVVRQGVPTEHLTLNTTQLRFHQIKERDIVQKQHLGRGTRTHIFSGHLLVQGGGENDQ
DDEFNNNSGGRKEIQVVLKILDQSDKDIDLGFLETASLMSQVSHNHLVFVHGVSVKGSEN
IMVEEFVEFGPLDVFLRKEKGSVNSQWKFIVAKQLASALNYLETKRLVHGNVCAKNILVA
RRGLESGTSPFVKLSDPGVSLSVLSREERLERIPWIAPECVDTGSHAANAADQWSFGVTL
LEICYDGDLPMSGGTLSEKERFYQQKGRLAEPLSPELAKFFSMCLTYEPLERPSFRTVLR
ELTGLIIINPNISPSEALPDTDPSVFHKRYLKMMRHLGEGHFGKVTLYLYDPANDGTGER
VAVKALKQDNSQVLEGWKKEIEILKSLYHSNIVKYKGCCTELGGQAVQLIMEYLPLGSLR
DYLPKRKLGVAQCLLFAQQICQGMVYLQSKRYVHRDLAARNVLVENDSLVKIGDFGLTKH
IPEGEIYYRVREDGESPVYWYAIECLKENKFSFSSDIWSFGVTLYEILTRCETRLSPPNV
CFDKMKEIKEEKNVMVLIKLLDTQWRLPRPKGCPHEVGMLMEQCWAAEPAKRPSFGSLIE
MFEAIRQTYNWQPHMNFSLA
NT seq
3483 nt
NT seq
+upstream
nt +downstream
nt
atgtccagaagagggaggtctaagagctcgagatctggggcgcccgccgccctgcgcgag
cccccccaggctgcgggcatccacgtctacctgttctggtctaaggagggcgaaaggtat
ctgtcccactcggccggaagagtcacggcggaggacctgtgcatctgcgctgcggaggct
gcagggatcacgcccctgtgccacacgttgtttgctctgtacaatccacattcacgctgc
tggtacagtccgaaccatgaattcagtccggacgactccaacctggttcttcacttccgt
atgaggttttactttagaaattggcacggactaaatgagaaggagccgactgtgtcccgc
tatgctcaccgatccggacaggggggttctcctctgtttgaaatcacatctttagagtac
ttattcttccaggccaaatatgaatttgtgaacgagatggtgcagatggaagacgttcag
tccgaggaggagggaagccgcttaaaaaacgagagcttggggatggctgtgcttcaactc
tcccaccaggcgatgctgacaggctgcaccttacaagatgctgctgataaagtcagcttc
ttgcactgcatcccaaggtccttcgccaagcaaatttccaaagacaacttcctgacgaaa
ctccggatccggcgggttttcagagagttcgtgcggaccttccagcagcacaccgtggac
aagggccgcctgggggcccaggagatcatgtacaggtacatcgccacgctggaacacctg
gcgccgcgtttcggatcggagaccttcccggtgtcccagttggagctgagggacgacggc
atcgagagcagctcttactccaactccacccgctacgagggcgcccccgaggacgacttc
atcggcccggccacccacgaggtcctggtgtccggcaccaagggggtccggtggaggccg
gtgtccgagcagaaggcgcaggccaacacctacctgaggaacgactacatgaagaccaaa
aagcaaccgtccagccagccgagcgaaaacactacggataaatggacctccttctgcgat
ttccgagaaataactcacatagccatcactggaacaaacgtgtgcattagcactctggac
aaccgctgcttggaggttcagatgaactccagccaggaggcccgttccttcatctccctc
ctggatgggtacaaccggctgactgcgttcgcccaccactatctttgtcatgaagtggct
cccccgagggtggtgctgagtgtagccaatggactgcacggacctatgcatgacgatttc
gtgctgctgaagctgaggcgggaggctgcagaggagggagctttcctcgtacgctggagt
gctctcgattatcgcggcatcatcctcgccgtcctgaacaaaaatgagaacggaacgaag
ccgggccacaagcagttccggattcagctcaagggtccgaagttctgcctggagggctgg
gatcgagagttctccagcgtgaaggagctcgcggagagcctgaagaccttcgtgctcaag
tctggttccgacagcttcacggtccgaaaatgctgtttgccgaaacacgcagagctctcc
aaccttgtggtggtccggcaaggtgttcccaccgaacacttgaccctgaacacgacgcag
ctgcgcttccaccagatcaaggagagagacatcgtgcagaagcagcacctgggccgcggg
accagaacccacatcttctcgggacatctgctggtccaaggcggaggagaaaacgaccag
gatgacgagttcaacaacaactctgggggccgcaaagagatccaagtggttctgaagatt
ctagaccaaagcgataaagacatcgatttaggctttttggaaactgcgagcctgatgagc
caggtgtcccacaaccacctggtgtttgtgcacggcgtgtcggtcaaagggtccgaaaac
atcatggtggaagaatttgtggagttcgggccgttggatgttttccttcgcaaggaaaag
ggatccgtgaactctcagtggaaattcattgttgcaaaacaactcgccagtgccctcaat
tatctcgagaccaagcggctggtccacggaaacgtctgcgccaagaacattctggtggcg
aggcgcggtctggagagcggcaccagtccttttgtcaagctgagtgacccgggagtttcc
ctgagtgtcctttcaagggaagagcgcctcgagcgcattccctggatcgcccccgagtgc
gtcgacaccggctcccacgccgccaacgccgccgaccagtggagctttggcgtcacgctg
ctcgaaatctgctacgacggcgaccttcccatgagtggcggcacgttgtcagagaaagag
cgcttctatcagcaaaagggtcgtctggccgaacctttgtccccggaactggcaaagttc
ttcagcatgtgtctgacctacgagccgctggagaggccttcgttccgcaccgtgctcaga
gagctcacagggctcatcatcataaatcccaacatctcccccagcgaggctctccccgac
acggaccccagcgtcttccacaaacgctacctgaaaatgatgcggcacctgggagagggt
cacttcggaaaggtcaccctctacctgtacgacccggccaacgacgggacgggagagcgc
gtggcggtcaaggctttgaagcaggacaacagccaggtcctcgagggctggaagaaggag
atcgagatcctgaagtctctctatcacagcaacattgtcaagtacaagggctgctgcact
gagctgggaggacaagctgtgcagctgattatggagtaccttcccctggggagtctgcgg
gactacctccccaaacgcaaactgggagtggcccagtgtctcttgttcgctcagcagatc
tgtcaggggatggtgtacctgcagtccaagcgatacgtccatcgagacctggctgcccgt
aatgtcttggtggaaaacgacagtttggtgaagattggagactttggcctaacgaagcac
atccccgaaggcgagatctactatcgtgttcgagaggacggggaaagcccggtgtactgg
tatgccattgagtgcttgaaggagaataaattttccttttcctctgacatttggtccttt
ggcgtcacgctgtatgagatcctgacccgctgtgaaacccggctgagccctccaaacgtc
tgttttgacaagatgaaggaaatcaaggaggagaagaatgtgatggtgctcataaaactg
ttggatacacagtggcgattgcctcgtcccaaaggctgccctcatgaagtggggatgttg
atggagcaatgttgggctgcggagccggccaaacgaccgtcattcggatccctcatcgaa
atgtttgaggctatccgccagacatacaactggcagccgcacatgaacttttctttggct
tag
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