Geobacter sp. M18: GM18_1123
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Entry
GM18_1123 CDS
T01421
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
geb
Geobacter sp. M18
Pathway
geb00290
Valine, leucine and isoleucine biosynthesis
geb00620
Pyruvate metabolism
geb01100
Metabolic pathways
geb01110
Biosynthesis of secondary metabolites
geb01210
2-Oxocarboxylic acid metabolism
geb01230
Biosynthesis of amino acids
Module
geb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
geb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
GM18_1123
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GM18_1123
Enzymes [BR:
geb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
GM18_1123
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
BtpA
CRT10
DUF6506
Motif
Other DBs
NCBI-ProteinID:
ADW12598
UniProt:
E8WM84
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All DBs
Position
1368022..1369608
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AA seq
528 aa
AA seq
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MSLVKLYDTTLRDGTQAEDISFLVEDKIRIAHKLDECGIHYIEGGWPGSNPKDVAFFKDI
KKEKLSQAKIAAFGSTRRAKITPDKDQNLRTLVDSKADAATIFGKSWDFQVHEALRIPLE
ENLEMIFDSLEYLKGHMPEVFYDAEHFFDGYKSNPEYAIKTLQAAQQAGADCIILCDTNG
GSMPYEIARIVNEVKKSITTPLGVHAHNDGECAVANTIISVEQGIVHVQGTINGFGERCG
NANLCSIIPALKVKMKRDCISDAQMRTLRELSRYVYELANLAPNKHQPYVGNSAFAHKGG
VHVSAIQRHPETYEHMRPELVGNTTRVLVSDLSGRANILAKATEFNINLDSKDPVTLEIL
EDIKSMENRGYQFEGAEASFELLMKRALGTHRKFFSVIGFRVIDEKRSEDDQPISEATIK
VKVGGKIEHTASEGHGPVNALDNALRKALEKFYPRLKDVKLHDYKVRVLPAGQGTASSIR
VLIESGDKEGRWGTVGVSSNVIEASYQALVDAIEFKLHKDEETAAPKK
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgagcctggtcaaactttacgatacgacgcttagggacggaacgcaggcggaggacatc
tctttcctggtcgaggacaagatccgcatcgcacacaagctggacgagtgcggtatccac
tacatcgaggggggatggcccggcagcaaccccaaggacgtcgccttcttcaaggacatc
aagaaggagaagctctcccaggcgaagatcgccgcgttcgggtcgacccggcgcgccaag
atcacccctgacaaggaccagaacctgcgcacgctggtggattccaaggccgatgccgca
accatcttcggcaagagctgggacttccaggtgcacgaggccctcaggatcccgctggag
gagaacctggagatgatcttcgactcgctggagtacctgaaggggcacatgcccgaggtg
ttctacgacgcggagcacttcttcgacggctacaagtccaaccccgaatacgccatcaag
accctgcaggccgcgcagcaggcgggtgccgactgcatcatcctgtgcgacaccaacggc
gggtcgatgccctacgagatcgcccggatcgtcaacgaggtgaagaagagcatcaccacc
ccgctcggcgtccacgcccataacgacggcgagtgcgccgtcgccaacaccataatttcg
gtggagcaggggatcgtgcacgtgcaggggaccataaacggtttcggagagcgctgcggc
aacgcaaacctctgctcgatcattccggccctgaaggtgaagatgaagcgcgactgcatc
tcggatgcccagatgcggacgcttcgggaactctcccgctacgtctacgaactggcgaac
ctggcgcccaacaagcaccagccctacgtcggcaactccgccttcgcccacaaggggggg
gtgcacgtctcggcgatccagcgccacccggagacctacgagcacatgaggccggaactg
gtcgggaacaccacccgcgtgctggtctccgacctctccgggcgcgccaacatcctggcc
aaggcgaccgagttcaacatcaacctggacagcaaggacccggtcaccctggagatcctg
gaagacatcaagtccatggaaaaccgcggctaccagttcgagggggccgaggcttccttc
gagctcctgatgaagcgtgccctgggcacccatcgcaagttcttctccgtgatcggcttc
cgggtcatcgacgagaagcgcagcgaggacgatcagcccatttccgaggcgaccatcaag
gtcaaggtgggtggcaagatcgagcataccgcgtcggaggggcacggcccggtcaacgcc
ctcgacaacgccctcaggaaggcactggagaagttctatcccagactgaaggacgtgaag
ctgcacgactacaaggtccgcgtgcttccggccgggcaggggaccgcttcctccatccgc
gtcctgatcgagtccggcgacaaggaagggcgctgggggaccgtcggtgtctccagcaac
gtgatcgaggcctcctaccaggcgctggtggacgccatcgagttcaagctccacaaggac
gaggagacggcggcaccgaagaaatga
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