Granulicatella elegans: LK443_05600
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Entry
LK443_05600 CDS
T09296
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
geg
Granulicatella elegans
Pathway
geg00300
Lysine biosynthesis
geg00550
Peptidoglycan biosynthesis
geg01100
Metabolic pathways
geg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
geg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LK443_05600
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LK443_05600
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LK443_05600
Enzymes [BR:
geg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LK443_05600
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UEA30778
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All DBs
Position
1129035..1130423
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AA seq
462 aa
AA seq
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MAIGTVAQIVKAVKAIDYQTDYRFDSIESVSFDTRKLTQNSLFIPLKGQTDGHDYIEQAI
EKGAKAVFWGRQDQTPPEGICAIWVDDPLEAFQELAKWYLEKVQPNVIGITGSSGKTTTK
DMTAAVLSSRYRVYKTQGNFNNDIGLPQTILDMPEDTEQLVLEMGMSDFGEIEFLSKLAK
PSVAVITLIGESHMENLGSRAGIAKAKLEILKGLHEKGSIIFPANEPLLEKELEEMQAEE
HFKVLPFGEGKSSVIQAENIQLFEDHTLFDLVKPSKHSVQLPVLGAYNVNNALAALQVGL
ECGVPLEQAIEAIQQFELTKNRTQWVEGIRGSKILNDAYNASPIAMKSVIQSFTSVASNG
RKIVVLGDIRELGEQSKALHASISEVMFPEEIQEVYLYGEEMSALYEALKSRFEESHLHY
VESDKTVLIQLLKEELQQNDQVLVKSSNGTGLLAVVEALKEA
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atggcaatcggaacagtggcacaaattgtaaaagctgttaaagcaattgattatcaaaca
gattatcgttttgatagtattgaatcagtttcatttgatacaagaaaattaactcaaaat
agtttatttattccattaaaaggacaaacagatggacatgattacattgaacaagcgata
gaaaaaggcgcaaaagctgtattttggggaagacaagaccaaactccaccagaaggaatt
tgtgcgatttgggtagatgatccactagaagctttccaagaattagcaaaatggtattta
gaaaaagtacaaccaaatgttatcggcattacaggaagttctgggaaaacaacaacaaaa
gatatgactgctgcagtactttctagtcgttatcgtgtatacaaaacccaagggaatttt
aataatgatattggattaccgcaaacgattttagatatgccagaagatacggaacaatta
gtattagaaatgggcatgagtgattttggtgaaattgagtttctaagcaaactagcaaaa
ccttctgtagcggtgattactctaatcggtgaatctcatatggaaaatttaggaagtcgt
gcaggaattgcgaaagctaaattagaaatcttaaaaggattacatgaaaaaggaagtatc
attttcccagccaatgaacctctattagaaaaagaactagaagaaatgcaagcagaagaa
cattttaaggtgttaccatttggagaaggaaagagcagtgtgattcaggctgaaaatatt
caattatttgaagaccatactctttttgacttagtgaaaccttccaaacattctgttcaa
ctacctgtattaggagcttacaatgtcaataatgcgctagctgctcttcaagtagggtta
gaatgtggagtgccattagaacaagccattgaagcgattcaacagtttgagttaacaaaa
aatcgtacgcaatgggtggagggcattcgtggttctaaaattttaaatgatgcttataat
gcaagtccaattgcgatgaaatctgtgattcaatcctttacatctgtagcttctaatgga
cgtaaaattgtcgtattaggagacattcgcgaattaggagaacaatcaaaagcattacat
gcaagtatttctgaagtaatgtttccagaggaaattcaagaagtgtatttatatggggaa
gaaatgagtgctttatatgaagcgttaaaatctcgctttgaagaatctcatttacattat
gttgaaagtgataaaactgtattgattcaattattaaaagaagagttacaacaaaatgat
caagtattagtaaaatctagtaatggtacgggattgttagcagttgtagaggcgttaaaa
gaagcataa
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