Gemella sp. ND 6198: CG018_00940
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Entry
CG018_00940 CDS
T05584
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
geq
Gemella sp. ND 6198
Pathway
geq00270
Cysteine and methionine metabolism
geq00480
Glutathione metabolism
geq01100
Metabolic pathways
geq01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
geq00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CG018_00940
09106 Metabolism of other amino acids
00480 Glutathione metabolism
CG018_00940
Enzymes [BR:
geq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
CG018_00940
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
Dala_Dala_lig_C
ATPgrasp_ST
GARS_A
ATP-grasp_4
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AXI26106
UniProt:
A0AAD0PXM7
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Position
complement(196002..198263)
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AA seq
753 aa
AA seq
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MNIRKIVKENNLEELFNAVKIGIEKEGQRVLESGDISKTGHPKTFGIRQKHPYIQTDFAE
SQIELITSPENSEKNVLRYLAAIHEVVLKNLPKDEFIWPLSIPVKLPNEEDIKVAQFEDK
WDVEYREYLVKKYGKYKQMVSGIHYNFQLSDNLMKSIADIEKKDIVDVKNNIYMKLARQF
IRYQWLLVYLYGASPLVEDKYYYNSNDKPKDYVRSIRMSRFGYVNDEDIVVSYNSLEEYI
DNIVSYVETGKLIAEKEFYSSVRFRGEDTVKKFLNNGIKYIEFRLFDLNPYAPFGILEKD
IRFIHLFIKTLVWLDEKNAVKSVEIGKEYSEKIALAHPLSKPEYLEEGLELLDNMKEMVK
ELKLSEADLTLIEEKENELIDSTLTIGGRLVRDYKNTSPLEVGMKLAKKYKKQATENYYS
LKAFENMELSTQALIEDAIRNGIKVDIIDENDQFIRLEWNNQVEYVKNGNMTSRDSYISP
LIMENKIVTKKILAEQGFRVPKGYEVSTLDDAVMVFNYIKNKPVVIKPKSTNFGLGITIF
KYGINDIETYSEAINLALKEDKDVIIEEFIEGTEYRFFVIEGKTKAVLLRVPANVVGDGV
HTIEELVEIKNNSSLRGDAKKTPLKKLELGEIEQLQLKEQGLTIHTVLKKGQVANLRENS
NISTGGDSIDMTDEVHSSYKKLAVKISDAMLAKVCGVDLIIPDIKSEVDNNNYGVIEANF
NPMMMMHIYPYKGKSRRLSLDVLRMLFPDKNII
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgaatattagaaaaattgttaaagaaaataaccttgaggaattgtttaatgctgtaaaa
attggcatagaaaaagaaggtcaacgagttctggaaagtggtgatatttctaaaacaggt
catcctaaaacattcggaataagacaaaaacatccatatattcaaacagattttgcagaa
tctcagatagagcttatcacttcacctgaaaactctgaaaaaaatgtacttcgttatctg
gcggcaatacatgaagttgttttaaaaaatcttcctaaagatgaatttatatggccgctt
agtattccggtaaaattacctaatgaagaagatattaaggtagcgcagtttgaagataaa
tgggatgtagaatatagagagtatttagtaaaaaaatacgggaaatataaacaaatggtt
tcgggtattcattataattttcagttatctgataatttaatgaagtctatagctgatatt
gaaaaaaaagatatagtagatgtaaaaaataatatttatatgaaattggctcgtcaattt
attcgctatcagtggctacttgtttatttatacggtgcaagtccgttagtagaggataag
tattattataatagtaatgataaaccgaaagattatgtaagaagtataagaatgagccgt
tttggttatgtcaatgatgaagatattgttgtatcttataactctttagaagagtatatt
gataatatagtatcttatgtagaaaccggaaaactcattgcagaaaaagagttctactct
agcgtccgttttagaggagaagatactgtaaaaaaatttttaaataacggtattaagtat
atagaatttagactattcgacttaaatccgtatgctcctttcggaattttggaaaaagat
attcgttttattcatttatttattaaaactttagtatggttagatgaaaaaaatgctgtt
aaatcggtagaaataggaaaagagtacagtgagaagatagctttggcgcaccctttgtca
aaacctgagtatttagaagaaggtttggaacttttggataatatgaaggaaatggttaaa
gagctaaaattatcggaagcagacttaactcttattgaagaaaaagaaaatgaattaata
gattcaacactcacaataggcggcagattggttagagattataaaaatacttcaccgctg
gaggtgggaatgaaacttgcaaaaaaatataaaaagcaagcaacggaaaattattattca
ctaaaggcatttgaaaatatggaactatctacccaagcgttaatagaagacgcaataaga
aatggaattaaagttgatattattgatgaaaatgaccaatttatacgtctggagtggaat
aatcaggtggagtatgttaaaaacggaaatatgacaagtagagatagttatatttcacca
cttattatggaaaataagatagttacgaaaaaaattctcgctgagcaaggctttagagta
cctaaagggtatgaagtatcaactttagatgatgctgttatggtatttaattatataaaa
aataaacctgttgtcattaaacctaaaagtacaaattttggattaggaattaccattttt
aagtatgggataaatgatatagaaacctattcagaagcgattaatttagcgctaaaagaa
gataaagatgtaataattgaagaatttatcgaaggaacggaatatcgcttttttgtaatc
gagggtaaaacaaaggctgttttacttagagttccggctaatgttgttggtgatggagtt
catacaatagaagagttggtagaaataaaaaataacagttcattacgtggtgatgccaaa
aaaacacctctaaaaaaattggagcttggcgaaatagaacagttgcaattaaaagagcaa
gggttaacgatacatacagttttgaaaaaaggacaagtagcaaacttaagagaaaattcc
aatattagtaccggtggtgattctatagatatgacagatgaagttcacagcagttataaa
aagttagctgtaaaaatttcggatgccatgttagcaaaagtgtgtggcgtggatttaata
ataccagatataaaatcggaagtagataacaataattatggagtgatagaagcaaacttt
aatcctatgatgatgatgcatatttatccatataaaggtaaatcacgaagattatcactt
gatgttttgagaatgctttttccggataaaaatataatataa
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