Georgenia sp. TF02-10: MF406_07065
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Entry
MF406_07065 CDS
T10482
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gew Georgenia sp. TF02-10
Pathway
gew00300
Lysine biosynthesis
gew00550
Peptidoglycan biosynthesis
gew01100
Metabolic pathways
gew01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gew00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MF406_07065
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MF406_07065
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MF406_07065
Enzymes [BR:
gew01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MF406_07065
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UNX55976
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Position
1568350..1569780
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AA seq
476 aa
AA seq
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MITMPLAEVAAVTGGHLAGPDAGAVVDGDVVADSRAAGPGSLFAAFAGARADGHDHVPAA
LAAGAAGALVSAPGAVLAAGAEPGRLVVVPDVAAALGALARHVLAALRAARPTDPPRVVA
VTGSVGKTTTKDLLARLLAPLGPLIAPPGSFNNEIGLPLTVLRADHATTTLVLEMGADHV
GNLAYLTSVAPPDVAVVLVVGRAHLGEFGGIENVARAKGELVSGLLPGGTAVLNADDPRV
AVMGALAPARVVTFGRGERPADVRATGVRLDDAGHPTFTLTAPAGSAEVTLALVGEHHVT
NALAAAAAALDLGVRLPAVAAALAGAGPASPHRMAVTDRDDGVRVVDDAYNANPDSVRAA
LAALTTLGAGRRRVAVLGEMLELGDAADAEHRAAGAAAARAADVVLAVAAAPLAAGARAA
AAHGTEVREAGDVDDAADQLAGLLRAGDVVLVKGSNGTGLWRLADRLTAPRPAVPR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgatcaccatgcccctggccgaggtcgccgccgtcaccggcgggcacctggccggcccc
gacgcgggcgccgtcgtcgacggcgacgtcgtcgccgactcccgggccgccgggccgggc
agcctgttcgccgccttcgccggcgcccgcgccgacgggcacgaccacgtccccgccgcg
ctggccgccggggccgccggcgccctggtcagcgcaccgggggcggtcctggccgccggc
gccgagccgggccggctcgtcgtcgtcccggacgtcgccgccgccctcggcgccctggcc
cggcacgtcctggccgcgctgcgcgccgcccggcccaccgacccgccgcgggtggtcgcg
gtgaccggctcggtcggcaagaccaccaccaaggacctgctcgcccgcctgctcgccccg
ctcggcccgctgatcgccccgcccgggtccttcaacaacgagatcgggctgccgctcacc
gtgctccgggccgaccatgccaccaccaccctggtgctggagatgggcgccgaccacgtc
ggcaacctggcctacctgacctcggtcgccccgcccgacgtcgccgtcgtcctggtcgtc
gggcgggcgcacctgggggagttcggcggcatcgagaacgtcgcccgggccaagggcgag
ctggtgagcgggctgctgcccggcgggaccgccgtgctcaacgccgacgacccgcgggtg
gccgtgatgggagcgctcgcccccgcccgggtggtcaccttcggccgcggcgagcgcccg
gccgacgtgcgcgccaccggggtccggctggacgacgccgggcaccccaccttcaccctg
accgccccggccggcagcgccgaggtcaccctcgccctggtcggggagcaccacgtcacc
aacgccctggccgccgccgcggcggcgctcgacctcggcgtccggctgcccgcggtggcc
gccgccctcgccggcgccggcccggccagcccgcaccggatggcggtgaccgaccgggac
gacggcgtgcgggtggtggacgacgcctacaacgccaaccccgactccgtgcgcgccgcg
ctggccgcgctgaccaccctcggcgccgggcggcggcgggtcgccgtgctcggcgagatg
ctcgagctcggcgacgccgcggacgccgagcaccgggccgccggtgccgcggcggcccgg
gccgccgacgtcgtcctcgccgtcgccgccgccccgctggccgccggcgcccgcgcggcc
gccgcgcacggcaccgaggtgcgcgaggccggcgacgtcgacgacgccgccgaccagctg
gccgggctcctgcgggccggggacgtcgtcctggtcaagggctccaacggcaccggcctg
tggcggctcgccgaccggctcaccgccccccggccggcggtgccccggtga
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