Glossina fuscipes (tsetse fly): 119636659 Help Entry 119636659         CDS       T09630                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism gfs  Glossina fuscipes (tsetse fly) Brite KEGG Orthology (KO) [BR:gfs00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:gfs04040]     119636659    04990 Domain-containing proteins not elsewhere classified [BR:gfs04990]     119636659 Ion channels [BR:gfs04040]  Voltage-gated cation channels   Ryanodine receptor    119636659 Domain-containing proteins not elsewhere classified [BR:gfs04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    119636659 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  119636659 NCBI-ProteinID:  XP_037888089 UniProt:  A0A9C5Z257 LinkDB All DBs Position Unknown AA seq 5125 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETDSQFGKGTGSGHRTLLYGNAILLRHHNSDMYLAC LSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLH TTKENELSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWG REAGQNIVIYEGGSVMSQARSLWRLELARTKWTGGFIMWFHPMRFRHITTGRYLGVNDNN ELILVKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCESGLW LSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFI SALEILQLNRRHSVFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDL FQEEGVLNLILEAIDKINSITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGR VEGSALYQKWYFEITMDHIEQTTHMMPHLRIGWANTTGYVPYPGGGKKWGGNGVGDDLYS FGFDGAYLWTGGRKTLVMDQVPEEPFIRKCDVIGVTIDLSVPVITFTFNGNKVRGCFREF NLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPPGFSPLVQCLMPHQILSLDPCFYFGN LNKNVLAGPWLIEDDTAFVPQPVDTSGVSLPSSVDQIKEKLAENIHEMWALNKIEAGWAW GEHRDDYHRIHPCLTQFEKLPPAEKRYDNQLAVQTLKTIVALGYYITMDKPPARIRPIRL PNELFMQANGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSE NLRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGNEALLAEALRLKFA AFRTYRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCNPGSMLGSEDTSWAFDGHNEE KVFGGASETFGKQCGPGDIVGVFLDVADHTISFSLNGELLMDALGGETTFADVTAEGVGF VPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENT EEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMGEFISETEKA RRWEEIKLRQYRLMRDAEIAQQQTSAHMDHMLKSGFTMSDIKGLNRNYDDTAEADENMRG PSRPPRKGSITRNITFEQDGLTLPEELQGSTLDINGLDGEALDEKKKRGRSPFKFFSKKS RDQSKEKTAGRAPEVSVERRNTVAHGRNVVNAQMAPRAPTLRLNNVEMPQTPTVQGPKPL SGGTLGQPPIESSGNEMFDAECLKLINEYFYGIRIYPGQDPTHVYVGWVTTQYHLHSKEF NKNRVRRGSVIIEDEYENPIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGCFVD TATGMIRFTCEGKETSHRWLMEPNTKLFPAIFVEATSKEILQIELGRTATTLPLSAAVLP TSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSMLALHI PEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCQHVDQKQLLYAIRSE YMSGPLRQGFYDLLIALHLESHATTMEVCKNEFIIPLGAELKALYEDEEMCHSLRSLVTE SVRPQMRMTDITIQSVSSETVPEIDQLYSPKFPLEIVREFVMEALQEAVEVNQVHNRDPI GWTNENLFLPLIKLTDRLLLVGVLTDEDVQKLLLMVDPETWDVNFEKDGKDEHRKGLLTM KMAEGAKLQMCYLLQHLYDIQLRHRVESIIAFSHDFVGDLQGDQLRRYIEIKQSDLPSAV AAKKTKEFRCPPREQMNQILCFKNLEPDDQENCTCGLDLRGRLHDFHDGLMKKVSLNALQ EPDEPESNGVEEVKTGPITKIFNFINTVKELEEGPKEVEEPEKKTPEEVFRKVLIKTIVS WAEESQIENPKLVREMFSLLVRQYDTVGELVRALGKTYVINNKARNDAAEMWVGLSQIRA LLPVQMSQDEEELMRKRLWKLVNNATFFQHPDLIRILRIHENVMAVMMNTLGRRAQAQSD APAQTEGMEGAPHKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLA RPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGLQSNSELIEKGYPDLGW DPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGLFRAIVEAN RMSERISERCKIQDEPEGTITGLNFTHPLPEGDEDEDYIDTGAAILNFYCTLVDLLGRCA PDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTILQTAPGEERPKSDMPSGLLPN NKQSIVLFLERVYGIETQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGNS ILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSQMQPA MLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSSQGQGSYGAASDEEKRLTML LFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTEEDYYGRQSGSPDQPQY DPNPIDTTNVHLTNDYNSLVQKFSEHYHDAWASRRLESGWTHGEIRSDTDRKHPRLKPYN MLSEYERERYKDPVRECLKALLAIGWTIEHSDIDVPQNNRGSVRRQSKPQIHDFQSEGSA FNYHPHPVDMTNLTLSREMQNMAERLAENSHDIWAKKKKEELDTCGGAIHPQLVPYDLLT DKEKRKDRERSQEFLKYMQYQGYKLHKPSKGGAEGEGGAAIIAVESRFSYSLLEKLIQYL DRATINMKLLKPSTTFSRRSSFKTASRDIKFFSKVVLPLMEKYFSTHRNYFIAVATATNN VGASLKEKEMVASIFCKLASLLRNRLTAFGPDVRITVRCLQVLVKGIDARTLVKNCPEFI RTSMLTFFNQTADDLGTTILNLQDGKYSHLRGTHLKTSTSLGYINQVVLPVLTAMFDHLA GCDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIDRHRPALGSCLGAYSS CFPVAFFEPHLNKHNQFSLLNRIADHSLEAQDIMVKMESCMPNLEAVLNEVDQFVESDKT YVDAPHIIDVILPLLCSYLPFWWAQGPDNVSPTSGNHVTMVTADHMNSLLRNVLKMIKKN IGNDNALWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMYHKEESMRGFIKSA SDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEAEELYNHVAEIFN IWSKSQYFLKEEQNFISANEIDNMALIMPTAARRSGITEGAPVTGGKAKKKKKNRDKKRD KDKEIQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMQEYDVIDFARNQLTLP DKLDPSDEMSWQHYLYSKLGKKEEPPTEEQAVEKSTNQNEKGKDKTEETVDRIVAMAKVL YGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARTYYEQWLE EENVGQEVMIEDLTQTFEESEKSKKDEEETEGKPDPLTQLVTTFCRGAMTERSGALQEDL LYMSYAQIAAKSCGEEEEEGGGEEEGEEAEGGGGGSEGERSRIHEQEMEKQKLLFHQARL SNRGVAEMVLLHISASKGVPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDVGFFT SIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQLTCEGHN LDWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIG VASQVFNTLTEVIQGPCSLNQQALAHSRLWDAVGGFLFLFSHMQEKLSKHSSQVDLLKEL LNLQKDMITMMLSMLEGNIVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLIESAS FQEIDMKNEGWVTPKDFRDKMEQSKNYTPEEMDFLLACCERNHEGKIDYAAFVDRFHEPS TEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIERVYFE IKDSNIEQWEKPQIKESKHAFFYSIVTEGGDKEKLEAFINFCEDAIFEMTHASGLMATDD GGGNVKRDTSYSSYMSEEEEERAARDPIRRTINAVKDGLKFGLYMLSPANIKHQIGVMQT KSVPELIIGFFKIIFYIFYYMGYANFAVVRYIFGILMNLMRGPAPEEVEAPPVEEETFGK ALPPLPTEEPPGTVQAFGLDINKEENGQYKVTVHESSASGTASSGEETAESSPEDAAASA EGQAVEGEAHHAEPVSIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKASTETQE TPAVHQIDFSQYGRRAVSFLARNFYNLKLVALVLAFSINFMLLFYKVTSFAEDEEASGED ELILGSGSGVGLAGSGLGSGEGSGEGGEDEEDIPELVHVNEDYFFMEHVIRVAAILHSLI SLCMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPEDGDVKSHWDKLVISAKSFPD SYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSAFVAQETESGGLIKYFMNIDWRYQIWK AGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVSYKTLRTILQSVTHNGKQLVL TVMLLTIVVYIYTVIAFNYFRKFYIQEEDDEVDKKCHDMFTCFVFHLYKGVRAGGGIGDE IGDPDGDDYEVYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQLQSVQENMESNCFI CGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWD FFPVGDCFRKQYEDELSGGGGGGGG NT seq 15378 nt NT seq  +upstreamnt  +downstreamnt atggctgaagcggaaggaggaagcgagcaggatgatgtttcattcttaaggacggaagac atggtctgcttgtcatgtacagctacgggcgaacgtgtatgcttagctgccgaaggtttt ggtaatcgtcattgttttttggagaatatagctgacaagaatgtaccacctgatctgtca caatgtgtatttgtcattgagcaggctttgtctgtgagagctctacaggagctggttacg gcagctggttccgaaacggattctcaatttggcaaaggtactggttccggtcatagaacg ttactgtatggcaatgctatactactgcgtcatcataacagcgacatgtatttagcttgc ctttcaacgtcgtcttctaatgacaaattatcatttgatgttggtctgcaagaacatagt caaggtgaggcatgctggtggacggttcatcctgcaagtaagcaacgtagtgagggtgag aaagtgcgtgtaggcgatgacttgattttagtctctgttgccactgaacgttatttgcac acaaccaaggagaacgaattgtcaattgtaaatgcgagctttcatgtgacacattggtcg gtgcaaccgtatggtactggcatatcccgcatgaagtatgtaggttacgtatttggtgga gatgtcttacgttttttccatggcggcgatgaatgtcttactatacccagcacgtgggga cgtgaagcagggcaaaatattgtcatttatgaaggcggttcggtcatgtcacaagcccgt tcattgtggcgtttggaattggcccgcactaaatggacgggcggttttataatgtggttt catccaatgcgatttcgacatatcactacaggacgttatttaggtgtcaacgataataac gaattaattttggtgaaaaaagaggaagcttcaatagctacaaccactttttgccttaga caggagaaggatgacgagaaaaaagtgctagaagataaagatctcgaagttatcggttct cctattatcaaatatggcgatactacagttattgtacagcattgtgagagcggtttgtgg cttagctacaaaagttatgaaacgaagaagaaaggagtcggcaaagttgaagagaagcaa gccattttgcatgaggaaggaaaaatggatgattgtttggacttttcgcgctcgcaggag gaggaatcgaaaacggctcgcgttatacgcaaatgtagcagtttatttacacaatttata agtgctttagaaattctgcaattaaatcgacgtcattcagttttctttcagaaagttaac cttaacgaaatggttatgtgtcttgaagatttaatcaattacttttcacagccggaggac gatatggaacatgaggaaaaacaaaatcgtttccgtgctttacgtaatcgtcaagatctc tttcaggaggaaggtgttctcaatctaattttagaagccattgataaaattaacagcata acgtctcaaggctttttagccagctttttagctggcgacgaaaccggtcaaagctgggac cttatttccacttatctgtatcaattgttagcggcgattattaaaggcaatcacacaaat tgcgcgcaatttgctaacagcaatcgtttaaattggctgttttctcgcttgggatcgcaa gcgtctagcgagggctctggcatgttggatgtacttcattgcgtattgattgattcaccc gaagctttaaacatgatgcgagacgaacatatcaaggtgattatatcactcttggagaag cacgggcgagatcctaaagttttggatgtcctgtgttcgctatgtgtaggtaacggagta gcggtgcgttcctcgcaaaataatatttgcgattttttgttgccgggaaaaaatttattg ttgcaaacgcaacttgttgatcatgttgccagtataaggccaaacatatttgtgggccgc gtagaaggttcggctctgtatcaaaaatggtactttgaaataacaatggatcatattgaa cagactacacatatgatgccgcatttacgcataggatgggccaacaccactggctacgtt ccatatccgggcggcggcaaaaaatggggcggcaacggagttggcgatgatttatattcg ttcggtttcgatggtgcctatttatggaccgggggacgtaaaactctggtcatggatcag gttcccgaagaaccgtttatacggaaatgtgatgttattggcgtaacaattgatttatca gtgcccgtaataacgttcactttcaatggcaacaaagtacgcggctgttttagagaattc aacttggatggcatgtttttcccagttatgagctgttcctcgaaattgagttgccgtttt ttgttcggcggagatcatggtcgactaaaatttgctccaccgcctggtttctcacctctc gttcagtgtctaatgccccatcaaatattgagtttggatccttgtttctatttcggtaat ttgaataagaacgttttagctggtccttggcttattgaggatgataccgccttcgtacca cagccggtcgatacttctggtgttagtttgccttcctcagtagatcaaattaaagagaaa ttggccgaaaacattcacgagatgtgggcccttaacaaaatcgaagccggttgggcttgg ggtgaacatagagacgattatcatcgcatacatccgtgtttgacacaatttgagaaattg cctccagctgaaaaacgttatgataaccagttagcagtgcaaacattaaaaactattgtt gctttgggttactatataactatggataaaccgccggccagaattagacccatacgcttg cctaacgagctgtttatgcaggcgaatggttacaaaccggctcctttagatctaagtgct gtcactctcactccaaagcttgaagaactagtagatcaattggccgaaaatacccataat ttgtgggcacgtgaacgcatacaacaaggctggacttatggacttaacgaagattccgaa aaccttcgcagtcctcatttagtaccctatgctaaagtcgatgaagccataaaaaaagct aatcgcgacacagcttctgaaactgtacgtactttgttagtttacggttatgttctagat ccaccaactggtgaggggaatgaggcactgctagctgaagcgttgcgtcttaaatttgct gcttttcgcacttatcgcgtcgaacgcaactatgcggttacttcgggcaaatggtatttc gaattcgaggttcttacctctggacctatgcgagtcggttgggcacgtgctgactgcaat ccaggttcgatgttgggtagtgaggacacgagttgggcattcgacggtcataacgaagag aaagtttttggcggagcaagtgaaacattcggtaaacaatgtggacctggtgatatagtt ggagtgttcttagatgtcgccgatcatacaatcagtttttcattaaatggcgaacttcta atggatgctttgggtggtgagacgacatttgctgacgtcacagctgaaggcgtgggcttt gtacccgcctgtacgcttggtgtaggccaaaaagctcgtttaatctatggtcaagatgta gattctttaaaattctttaccacatgtggccttcaagaaggttatgaaccgttttgcgtt aacatgagacgtcctgttacgcactggtacactaaggatcaaccaattttcgaaaacact gaagaaatgcccgactgccgtattgacgtcacacgtatacctggtggcgcggatacaccg cctcatttgaaaatttcacacaatactttcgaaacaatggaaaaagccaattgggaattt ttacggttatccttaccagtgacgtgtatgggggaattcatctcggaaactgaaaaggct cgacgctgggaggaaattaaactacgccagtatagattgatgcgcgatgcagaaatagct cagcagcaaacatccgctcacatggatcatatgttgaagagtggctttactatgagcgac ataaaaggccttaatcgcaactatgacgatactgccgaagctgatgaaaatatgcgaggc ccttctagaccgcctcgtaaaggttcaataacgcgcaatattacatttgaacaagatggt ctcactttgccagaagaacttcaaggttccacacttgacattaatggtttagatggagag gctttggatgaaaaaaagaaacgtggtcgtagcccattcaaattcttctcgaaaaaatca cgtgatcaaagcaaagaaaaaacggctggacgcgctccggaagtatctgtagaacgtcgc aacaccgtcgcacatggtcgtaatgttgttaacgctcaaatggctccccgagctcccact ttacgtctaaataacgttgaaatgccacaaacgccaaccgtgcagggtcccaaaccttta agcggtggtactcttggccagccgcctatcgaatcatcgggcaacgaaatgtttgatgcc gaatgcttaaaattaataaatgaatacttttacggcataagaatttatcctggtcaagat cctactcacgtatatgttggctgggtgacaacccaataccatttgcacagtaaagaattt aataaaaatcgcgttcgacgtggctctgtaattattgaagacgaatacgaaaatcccata gagcgcatcgatcgccaaagctgttatgtggtacgtgcagatgaactcttcaatgaagta actcaagatgcctccggtaaaggcgcttcgcaaggcatgtttgttggttgttttgtggac actgctactggcatgatacgttttacttgtgaaggaaaagaaacttcacaccgctggctc atggagcccaatactaagctgttcccggccatttttgtggaagctacaagcaaggaaatc ttacaaatagaattgggacgcactgccacaacactgcctctctccgctgctgtactgcct acaagtgataaacatattaatccgcaatcaccgccacgtctaaaagttcaatgtcttcga ccacatcaatgggcacgggtgccaaataccgcattgcaagttcatgccttaaaactatca gacattcgtggatggtctatgctctgtgaggatcccgtgtctatgctagctttgcacatt cccgaagaggatcgttgtattgacattttagaactcatagaaatggacaaattgctttcc ttccatgctcacacactcaccttgtatgcagcgctttgctatcaatccaattacagagca gctcatgctttatgtcaacatgtcgatcaaaaacaattgctctatgctatacgttccgaa tatatgagtggaccgttacgacagggcttctatgatctgttaattgcattacacttggag tctcacgctactacaatggaagtttgtaaaaatgaattcattattcctctgggagcagaa ttgaaggccctttatgaagatgaagaaatgtgccattcattaagatctttagttactgaa tcggttcgaccacaaatgcgtatgaccgatattactatacaaagtgtttctagcgagact gtgccggaaatcgatcaactctactctcccaagtttcccttagaaattgttcgcgaattt gtaatggaagcattgcaagaagctgtggaagttaatcaggttcacaacagagacccgatt ggttggaccaatgaaaaccttttcttacctttaatcaagcttacggatcgtctacttctc gtcggcgttcttacggatgaagacgtccaaaaacttctgcttatggttgatcccgaaaca tgggatgttaacttcgagaaagatggaaaagatgagcaccgcaagggcttactaactatg aagatggctgaaggagcaaaattacaaatgtgttatcttcttcaacatttatacgacata cagttacgacatcgtgtagagagcatcattgccttttctcatgactttgtaggagatctg caaggtgatcagttgcgacgttacatagaaatcaagcaatccgatcttcccagcgccgta gcagctaagaaaactaaagagttccgttgtccacctcgagaacagatgaatcaaattcta tgttttaagaatcttgagcccgatgatcaagaaaactgtacctgtggtttagatttgcga ggacgcttacatgattttcatgatggccttatgaagaaggtgtctttaaatgctttgcaa gagcctgatgagccagaaagcaacggggtagaagaagttaaaactggaccgataacgaaa atcttcaatttcattaacactgtaaaagaattggaagaagggcctaaggaagttgaggaa cctgaaaagaaaactcctgaagaagtattccgcaaagtcctaattaagacaattgtaagt tgggctgaggaatcacaaattgaaaatccaaaattggtgcgtgagatgtttagtttactc gtacgccaatacgacacagtaggggagctcgtgagagctcttggtaagacttatgttatt aataacaaagcccgaaacgacgcagctgaaatgtgggtgggtttaagtcaaattcgtgct ctgctgccagtacagatgagtcaggatgaagaagaattaatgcgaaaacgtttgtggaaa ttagttaataatgccacattcttccaacatcccgatttaataagaatccttagaatacat gaaaacgtaatggccgtgatgatgaatacacttggtagacgggcgcaagcgcaaagtgat gccccagcccaaacagagggaatggaaggagctccacataaggagaaggatacttctcac gaaatggtggtggcttgttgccgtttcctctgttatttctgtagaactggaagacagaat caaaaggctatgtttgaccacttcgattttctacttgacaacgcgaatatacttttggct agaccaagtttgcgcggttctactcctttagacgtggcatactcaagtttaatggagaac acagaattagctctggcacttagagaacactatttagaaaaaattgcaatttatctttca cgttgcggtcttcaaagtaattctgaacttattgaaaaggggtatcccgacttgggttgg gatccggttgaaggcgaacgctatttggactttttgcgttactgcgtttgggtaaatggt gagagcgttgaagagaatgcaaatcttgttattcggttgctcatacgccggccagaatgt ttaggtccagcgttgagaggagaaggtgaaggccttttccgtgctatagttgaagccaat cgcatgtctgaacgcatctcagagcgttgcaagatacaagacgaacctgaaggtaccatc actggtctcaacttcacacatccattgccggaaggcgatgaagatgaagattatattgat accggtgcagcaatactaaatttctactgcactcttgttgatcttttgggtagatgtgcc cccgatgcttcagttatagagcagggtaagaacgaatcactgagagctagagctattttg agatctcttgtgccacttgaggatctgcaaggtgtcctcagcttaaaattcaccattctg caaactgctccaggtgaagaaaggcccaagtccgacatgccatccggtttgttgcccaac aacaagcaaagcatagtcttatttttggagcgcgtttatggtatagaaactcaagacctt ttttatcgcttattggaagatgcctttctacctgatctaagaaccgcgacaattttagat aaaagcgacgggtctgagagtgatatggccctggcaatgaatcgctacattggtaactcc attctacctctattaatcaaacattcaaaattttataatgaagcagaaaactatgctagt ttactagacgccactctccacacagtctatagattatctaaaaatcgtatgctcaccaaa ggtcaaagagaagccgtatcagactttttggtagccttaacatcacaaatgcagccagct atgttactcaaattattgcgtaagctaactgttgatgtttcaaagctatcggaatacact accgtggccttacgacttctgactttacatttcgatcggtgtgccaaatactatggttct agccaaggtcaaggctcatatggcgctgcctcagatgaagaaaaacggcttacaatgctt ttattttcgaatatatttgactctcttagtaacatggactacgatccagaattgtttggc aaagctcttccttgtctgattgcaatcggatgtgctttgcctcccgattacagtttatct aaaaatacggaagaagactattatgggcgtcaatcgggctctcctgatcagccacaatac gatccaaaccctatcgacaccacaaatgtacatttaactaatgattacaattctttagtg cagaaattcagcgaacactatcacgatgcttgggcaagtagacgtttggaaagcgggtgg acacatggggaaattcgttctgacactgatcgtaaacatccaagactgaagccctataat atgctaagtgaatatgaacgcgaacgctataaggatcccgttagggaatgtttgaaagcc ctcctggctataggttggacaattgagcattctgatattgacgtgcctcaaaacaatcgt ggttcagtgagacgtcagtcaaaacctcaaattcatgattttcagagtgaaggtagtgca tttaactaccatccacaccctgtggatatgacgaatcttacgctcagccgtgaaatgcaa aatatggcagagcgtttagccgaaaattctcacgatatttgggctaaaaagaaaaaggaa gaattagacacttgtggtggtgcgatacatcctcagctagtgccttatgatttgctaacg gataaagagaagcgtaaagatcgcgagcgttcacaagagtttcttaaatacatgcaatac cagggttataaattgcacaaaccttctaagggcggagcagagggtgaaggtggtgcagct ataattgcggtggagtcacgtttttcttattccttactggaaaaattgatacaatacctg gatcgggccactatcaacatgaaattgttaaaaccctctactacttttagcagacgctca tctttcaaaactgcttctcgggatatcaaattcttctccaaagtcgtgctgccgcttatg gaaaagtatttttcaacgcatcgtaactacttcattgccgtagctacagctactaataat gtgggagcatcattaaaagagaaggaaatggtcgcttcaatattttgtaaattggcttca ttgttacgtaatcgcttgactgctttcggtcctgatgtgcgcataacggttcgttgtctt caagtgctagtcaaaggcattgatgctaggacattagtgaagaattgccccgaatttatt aggacgtcaatgttaacattctttaatcaaacagccgatgatttgggtacaacaatctta aatttgcaggatggcaaatacagtcacctaaggggaacacatctgaagacttctacttct cttgggtacatcaatcaagtagttttgccagtgctaacagctatgttcgaccacttggct ggttgtgactatggcagcgatttgttgttggatgagatacaagttgcttcatataaaatt ttagcagccttatatcatttagggactgatggaactttaacgcatgacagaaaatattta aaaaccgaaattgatagacatcgcccagctctaggttcctgtttgggagcctacagttct tgctttcctgtggcgttctttgaaccccatttgaataaacacaatcagttctccttactc aatcgaatagcggatcattctttagaagcccaagacattatggtaaaaatggaaagttgc atgcccaatttagaggcggttttgaacgaagttgatcaatttgtagaatctgataaaacc tacgttgatgctccacacattattgatgtgatcttgcctttgctatgttcttatctgcca ttctggtgggctcagggacctgataatgtaagtccaacgagcggcaatcacgtgacaatg gtcacagccgatcatatgaactcgttgctgcgtaatgtcttgaaaatgattaagaagaat ataggcaacgacaatgctctttggatgaccagaattgcggcatacacacaacaaattatc attaatacttcggaagagttgcttaaagatccctttttaccgttagcggaacgcgttaag aaacgtactgaaaatatgtatcataaagaagaaagcatgcgtggttttattaaatcggcc agcgacgatacatcacaggtagaaacacagctacaagaagactggaatttactggtacgc gatatctactcgttttatcctttgttaattaaatacgtcgatttgcaacgtaatcactgg ttaaaagacaacatcccagaagccgaagagttatataatcacgtggccgaaatattcaat atttggtccaagagtcagtacttcttgaaagaagagcagaacttcatttccgccaatgaa attgacaatatggccttaattatgccgactgcagcccgacggtcaggtataactgaaggt gctccggttacgggcggcaaagcaaaaaagaagaaaaagaatcgtgacaaaaaacgcgat aaagataaagaaattcaagcgagtcttatggtagcttgtttaaaacgattactgccggta ggattgaacctctttgctggacgtgagcaggaactggtacagcattgcaaggatcgttat ttgaagaagatgcaagaatacgatgtcatcgatttcgcacgcaatcaactaacgctaccc gacaaactagatccttcggatgaaatgtcgtggcaacattatctttactcaaaattgggc aaaaaagaggaaccgccaaccgaagagcaggccgtcgaaaagtccaccaatcaaaacgag aaaggcaaagacaagactgaagagacggtcgatcgtatagtagcaatggccaaagttctt tacggtctacatatgatcgaccatccccaacagcagagtaaaaacgtctacaggagcgtt gtttccatacaacggaagcgtgcggttattgcatgtttccgtcaaacatctttacattct ttacccagacatcgtgcttgcaatatatttgctcgcacttactatgaacaatggctagaa gaggaaaacgttggccaagaagtgatgattgaagacctaacgcagactttcgaagagtct gagaaatcgaaaaaagacgaagaagaaacagaaggcaaaccggatccgttaacacaactg gtgacaaccttctgtcgtggagccatgacagagagaagtggagctttacaagaggatctt ttgtacatgtcttatgctcagatagctgccaaatcctgtggtgaggaagaggaggaaggc ggaggcgaagaagaaggtgaagaagccgaaggtgggggtggtggtagtgaaggtgaacgt agcaggattcacgaacaagaaatggaaaagcaaaagctgcttttccatcaagcccgtctc tccaatcgtggtgtagcagaaatggttttactacatatttccgcttcaaaaggagtacct tcggaaatggtgatgaccactttaaatctcggcattgctatactgcgtgggggcaatatt gacattcagatgggtatgttgaaccatttgaaagagaaaaaggatgtaggcttctttaca tcgattgctggtttaatgaactcgtgcagtgtcttggatttggatgcgtttgaacgtaac accaaagcagaaggtcttggtgtcggttcggaaggcgctgccggtgagaaaaatatgcat gatgccgaatttacctgtgccttgttccgtttcatacagttaacatgtgaaggtcataac ttagactggcagaattatttgcgtacacaagcgggcaacactacgacggtcaatgtagtc atctgcaccgttgattatcttttgcggttacaagaatctattatggatttctattggcat tactccagcaaagaaataattgatccggccggcaaagctaactttttcaaggccatcggt gtagccagtcaagtgtttaatacgctaacagaagtcatccagggtccttgtagtttaaat caacaggctctggctcattcccgtttatgggatgctgtaggtggttttcttttcctattc tcccacatgcaagagaaattatccaaacactctagtcaagtggatttgctgaaggagcta ctaaatttgcaaaaagatatgataaccatgatgttgtccatgttggagggaaatatagta aatggtacaatcggcaaacaaatggtcgacactcttgttgaatctgctagcaatgttgaa ttaattttaaaatatttcgacatgttcttaaagctaaaggatcttattgaatcggctagc ttccaagaaattgatatgaaaaacgaaggttgggttacacccaaagattttagggacaaa atggaacaatcgaaaaattacacaccggaggaaatggatttccttttggcttgttgtgaa cgcaatcacgaaggaaaaatagattacgccgcctttgttgatcgattccatgagccctct acagaaattggttttaatttggccgttttactgaccaatttaagtgaacatatgcctaat gaaccacgcttagcccgtttcttggaaactgccggttcggttttgaactactttgaacca ttcctgggacgtattgagattttgggcagttccaagcgcatcgaacgtgtttactttgag atcaaggattcaaatattgagcagtgggaaaaaccccaaattaaggagtcgaaacacgcc ttcttctactctattgtaaccgaaggtggcgacaaggaaaaacttgaggcgtttattaat ttctgtgaggatgctatttttgaaatgactcatgcttctgggctaatggctacagacgat ggcggtggcaacgttaaacgagatacctcctacagttcttacatgagtgaagaggaggaa gaacgagcagctcgagacccgatacgacgaactatcaatgccgtgaaagatggtttaaag tttggcctgtacatgctaagtccggcgaatatcaagcaccaaattggtgtgatgcaaaca aaatcggtacccgaattgattattggtttctttaagattattttttatatattctactac atgggctacgccaactttgctgttgttcgctatatatttggtatactaatgaatttgatg cgtggacctgctccggaagaagtggaagcgccgcctgtcgaagaagaaacatttgggaaa gccttacctccgctacccacggaagaaccgccaggcacagtgcaggcttttgggctggac ataaataaagaagaaaatggtcaatacaaggttacagtgcatgaatcatcggctagtggt actgccagctcgggtgaagagactgcagaatctagtcctgaggatgcagcagcttcagct gaaggccaagctgtcgaaggtgaggctcaccatgcagaacctgtgtcaattgtggatttg ttgggaggagaagcagccaagaaagccgcgcaagaacgtcaagaagcgcagaaagcccaa gaagcagcaatggcctctattgaagctgaagctaaaaaagcttctacggaaacccaagaa actccagctgttcatcaaatagacttttcgcaatatggtcgtcgagcagtaagctttttg gcacgtaatttttacaatctaaaattggtggctcttgtgctggctttcagtatcaatttt atgctattgttctataaagtaacatcgtttgcggaagatgaagaagcttctggggaagat gaattgatattaggttcaggttctggtgttggcttggccggttcgggtttaggttcaggt gaaggttcaggtgaaggaggggaggacgaggaagatattccggaattagtgcatgtaaac gaagactatttctttatggaacatgtgatacgtgtagcagccattttacatagtctgatt tcgttatgcatgctaatcgcctattatcatctaaaggtgcctttagccatattcaagcgg gaaaaggaaatcgctcgtcgtcttgaatttgatggtctttttattgccgaacaacccgaa gatggcgacgtgaaatcccactgggacaaattggttatatcagctaaatcattcccggat agctattgggataaattcgtcaagaaaaaagtccgccaaaaatacagtgaaacttacgac tttgattcaatttcaaatttattgggcatggaaaaaagtgcttttgtggctcaggagacc gaaagtggcggtttaattaaatattttatgaacattgattggcgatatcagatatggaag gcaggagttacatttacagacaacgcttttctttactcattgtggtatttctccttctca gtaatgggaaacttcaataattttttctttgctgctcatttactagatgtggccgtaagc tataaaactttgcgtaccattttacaatcggtaacacataacggtaaacaattggtatta acagtcatgctgcttactattgtcgtgtacatatacactgtgattgccttcaattatttc cgcaagttctatattcaagaggaggatgacgaagttgataagaagtgccatgacatgttc acctgttttgtattccacttatataaaggcgtaagagctggcggcggtattggtgatgaa attggtgatccagatggagacgattacgaagtgtatcgtattatattcgacataacgttc ttcttctttgttattgttatattgttggctattatccaaggtttgattattgacgctttt ggtgagctccgtgaccaattgcaatcggttcaggaaaatatggaatcaaattgctttatt tgtggcatgggtaaagacttcttcgatatagtaccgcatggctttgatacgcatgttcaa aaggagcacaatctcgccaactatatgttcttcctaatgcatttgattaataaaccagat acggaatacactggtcaagagacttacgtatggaatatgtatcaacagcgcagttgggac ttcttcccggtcggtgattgcttccgtaaacaatatgaagatgaattgtcaggcggcggt ggcggcggaggcggctaa

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