Geobacillus sp. GHH01: GHH_c27350
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Entry
GHH_c27350 CDS
T02455
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
ggh
Geobacillus sp. GHH01
Pathway
ggh00290
Valine, leucine and isoleucine biosynthesis
ggh00660
C5-Branched dibasic acid metabolism
ggh01100
Metabolic pathways
ggh01110
Biosynthesis of secondary metabolites
ggh01210
2-Oxocarboxylic acid metabolism
ggh01230
Biosynthesis of amino acids
Module
ggh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ggh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
GHH_c27350 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GHH_c27350 (leuB)
Enzymes [BR:
ggh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
GHH_c27350 (leuB)
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Motif
Pfam:
Iso_dh
TAP42
Motif
Other DBs
NCBI-ProteinID:
AGE23246
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Position
complement(2726863..2727978)
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AA seq
371 aa
AA seq
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MGNYRIAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEET
LRLCRESDAVLLGAVGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSASP
LKPDLVQGVDFVIVRELTGGIYFGQPSGRVVENGEEKAVDTLLYKKEEIERIVRMAFILA
RGRKKKVTSVDKANVLSSSRLWREVAEEVAKQFPDVTLEHMLVDNAAMQLIRAPKQFDVI
VTENMFGDILSDEASMLSGSLGMLPSASLSASGPSLYEPVHGSAPDIAGMNKANPIAAIL
SAAMMLRLSFGLTAEAEAVEHAVRQALDQGLRTADLAPSGGRIVSTNEMVEEIKTAVLDY
TAIAQIMTVYA
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
atgggaaactatcggattgccgtcttgccaggggatggcatcggaaaagaagtgacgtcc
ggagcggtcgaggtattgaaagcggtcggcatccggtttggccacgagtttacgtttgaa
tatggattgatcggtggagcggcgatcgatgaggcggggacgccgctccccgaggaaacg
ctccgcctttgccgagaaagcgatgcggtgctgcttggggcggtcggcggtccgaagtgg
gatgacaaccctccgcatttgcgcccggaaaaaggattgcttgccattcgcaagcagctc
gacttatatgccaacttgcggccggttgtttgctatgacagtttggtttccgcttcgccg
ttaaaaccggatctcgtgcaaggcgtcgattttgtcatcgtccgcgagctgaccggcggc
atttacttcggccagccgagcggccgcgtcgtcgaaaacggcgaagaaaaagcagtggac
accttgctatataaaaaggaagaaattgagcggatcgtccgcatggcgtttatactcgca
cgcgggcggaagaaaaaagtgacttcggtcgacaaggcgaacgtcctttcgtcaagccgt
ctatggagggaagtggccgaagaggtggcgaagcagtttccggacgtcacgcttgagcat
atgcttgttgacaatgccgcgatgcagctcatccgtgcgccgaagcagtttgatgtcatt
gtgacagaaaacatgtttggcgacattttaagcgatgaagcctccatgttgtccggttcg
ctcgggatgctgccgtcagccagcttatccgcttccggtccgagcttgtatgagccggtg
cacggttcagcgcctgatatcgccggcatgaacaaagccaatccgattgcggcgattttg
tcagctgcgatgatgcttcgcctgtcgttcgggctcaccgcggaagcggaggcggtcgag
cacgcggtgcggcaggcgctcgatcaaggtttgcgcactgccgacttggcgccaagcggc
ggccgcatcgtatcaacgaacgaaatggtcgaagaaatcaaaacagcggtgctggattat
acggccattgctcaaattatgaccgtttatgcctaa
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