KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101126389
Entry
101126389         CDS       T02442                                 
Symbol
KIT
Name
(RefSeq) mast/stem cell growth factor receptor Kit isoform X7
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04015  Rap1 signaling pathway
ggo04072  Phospholipase D signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04640  Hematopoietic cell lineage
ggo04916  Melanogenesis
ggo05200  Pathways in cancer
ggo05221  Acute myeloid leukemia
ggo05224  Breast cancer
ggo05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101126389 (KIT)
   04014 Ras signaling pathway
    101126389 (KIT)
   04015 Rap1 signaling pathway
    101126389 (KIT)
   04072 Phospholipase D signaling pathway
    101126389 (KIT)
   04151 PI3K-Akt signaling pathway
    101126389 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    101126389 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    101126389 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101126389 (KIT)
   05230 Central carbon metabolism in cancer
    101126389 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    101126389 (KIT)
   05224 Breast cancer
    101126389 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ggo01001]
    101126389 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ggo04090]
    101126389 (KIT)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101126389 (KIT)
Protein kinases [BR:ggo01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   101126389 (KIT)
CD molecules [BR:ggo04090]
 Proteins
  101126389 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 Ig_4 V-set Ig_6
Other DBs
NCBI-GeneID: 101126389
NCBI-ProteinID: XP_004038734
Ensembl: ENSGGOG00000015440
LinkDB
Position
3:complement(join(71607756..71607884,71609030..71609135,71609490..71609589,71609701..71609812,71613102..71613224,71614289..71614416,71614867..71614958,71616801..71616951,71618164..71618274,71618358..71618462,71618743..71618869,71618961..71619067,71620260..71620441,71622604..71622718,71636707..71636822,71638957..71639146,71642358..71642526,71646494..71646630,71647695..71647976,71650478..71650747,71687995..71688061))
AA seq 972 aa
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFVPDPKAGIMIKSVKRAYH
RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFVCYANNTFGSAN
VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNASIAFNVYVNTKPEILTYDR
LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
SAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILT
YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVV
EATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGG
PTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDM
KPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLA
SKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNC
VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMK
TCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTA
SSSQPLLVHDDV
NT seq 2919 nt   +upstreamnt  +downstreamnt
atgagaggcgctcgcggcgcctgggattttctctgtgttctgctcctactgcttcgcgtc
cagacaggctcttctcaaccatctgtgagtccaggggaaccgtctccaccatccatccat
ccaggaaaatcagacttaatagtccgcgtgggcgacgagattaggctgttatgcactgat
ccgggctttgtcaaatggacttttgagatcctggatgaaacgaatgagaataagcagaat
gaatggatcacggaaaaggcagaagccaccaacaccggcaaatacacgtgcaccaacaaa
catggcttaagcaattccatttatgtgtttgttagagatcctgccaagcttttccttgtt
gaccgctccttgtatgggaaagaagacaacgacacgctggtccgctgtcctctcacagac
ccagaagtgaccaattattccctcaaggggtgccaggggaagcctcttcccaaggacttg
aggtttgttcctgaccccaaggcgggcatcatgatcaaaagtgtgaaacgcgcctaccat
cggctctgtctgcattgttctgtggaccaggagggcaagtcagtgctgtcggaaaaattc
atcctgaaagtgaggccagccttcaaagctgtgcctgttgtgtctgtgtccaaagcaagc
tatcttcttagggaaggggaagaattcacagtgacgtgcacaataaaagatgtgtctagt
tctgtgtactcaacgtggaagagagaaaacagtcagactaaactacaggagaaatataat
agctggcatcacggtgacttcaattatgaacgtcaggcaacgttgactatcagttcagcg
agagttaatgattctggagtgttcgtgtgttatgccaataatacttttggatcagcaaat
gtcacaacaaccttggaagtagtagataaaggattcattaatatcttccccatgataaac
actacagtatttgtaaacgatggagaaaatgtagatttgattgttgaatatgaggcattc
cccaaacctgaacaccagcagtggatctatatgaacagaaccttcactgataaatgggaa
gattatcccaagtctgagaatgaaagtaatatcagatacgtaagtgaacttcatctaacg
agattaaaaggcaccgaaggaggcacttacacattcctagtgtccaactctgatgtcaat
gcttccatagcatttaatgtttatgtgaatacaaaaccagaaatcctgacttacgacagg
ctcgtgaatggcatgctccaatgtgtggcagcaggattcccagagcccacaatagattgg
tatttttgtccaggaactgagcagagatgctctgcttctgtactgccggtggatgtgcag
acactaaactcatctgggccaccgtttggaaagctagtggttcagagttctatagattct
agtgcattcaagcacaatggcacggttgaatgtaaggcttacaacgatgtaggcaagact
tctgcctattttaactttgcatttaaagagcaaatccatccccacaccctgttcactcct
ttgctgattggtttcgtaattgtagctggcatgatgtgcattattgtgatgattctgacc
tacaaatatttacagaaacccatgtatgaagtacagtggaaggttgttgaggagataaat
ggaaacaattatgtttacatagacccaacacaacttccttatgatcacaaatgggagttt
cccagaaacaggctgagttttgggaaaaccctgggtgctggagctttcgggaaggttgtt
gaggcaactgcttatggcttaattaagtcagatgcggccatgactgtcgctgtaaagatg
ctcaaaccaagtgcccatttaacagaacgggaagccctcatgtctgaactcaaagtcctg
agttaccttggtaatcacatgaatattgtgaatcttcttggagcctgcaccattggaggg
cccaccctggtcattacagaatattgttgctatggtgatcttttgaattttttgagaaga
aaacgtgattcatttatttgttcaaagcaggaagatcatgcagaagctgcactttataag
aatcttctgcattcaaaggagtcttcctgcagtgatagtactaatgagtacatggacatg
aaacctggagtttcttatgttgtcccaaccaaggccgacaaaaggagatctgcgagaata
ggctcatacatagaaagagatgtgactcctgccatcatggaggatgacgagttggcccta
gacttagaagacttgctgagcttttcttaccaggtggcaaagggcatggctttcctcgcc
tccaagaattgtattcacagagacttggcagccagaaatatcctccttactcatggtcgg
atcacaaagatttgtgattttggtctagccagagacatcaagaatgattctaattatgtg
gttaaaggaaacgctcgactacctgtgaagtggatggcacctgaaagcattttcaactgt
gtatacacgtttgaaagtgatgtctggtcctatgggatttttctttgggagctgttctct
ttaggaagcagcccctatcctggaatgcctgtcgattctaagttctacaagatgatcaag
gaaggcttccggatgctcagccctgaacatgcacctgctgaaatgtatgacataatgaag
acttgctgggatgcagatcccctaaaaagaccaacattcaagcaaattgttcagctaatt
gagaagcagatttcagagagcaccaatcacatttactccaacttagcaaactgcagcccc
aaccgacagaagcccgtggtggaccattctgtgcggatcaattctgtcggcagcaccgct
tcctcctcccagcctctgcttgtgcacgacgatgtctga

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