KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101127257
Entry
101127257         CDS       T02442                                 
Symbol
CACNA1A
Name
(RefSeq) voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X2
  KO
K04344  voltage-dependent calcium channel P/Q type alpha-1A
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04020  Calcium signaling pathway
ggo04721  Synaptic vesicle cycle
ggo04723  Retrograde endocannabinoid signaling
ggo04724  Glutamatergic synapse
ggo04725  Cholinergic synapse
ggo04726  Serotonergic synapse
ggo04727  GABAergic synapse
ggo04728  Dopaminergic synapse
ggo04730  Long-term depression
ggo04742  Taste transduction
ggo04930  Type II diabetes mellitus
ggo05017  Spinocerebellar ataxia
ggo05032  Morphine addiction
ggo05033  Nicotine addiction
ggo05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101127257 (CACNA1A)
   04020 Calcium signaling pathway
    101127257 (CACNA1A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    101127257 (CACNA1A)
   04727 GABAergic synapse
    101127257 (CACNA1A)
   04725 Cholinergic synapse
    101127257 (CACNA1A)
   04728 Dopaminergic synapse
    101127257 (CACNA1A)
   04726 Serotonergic synapse
    101127257 (CACNA1A)
   04730 Long-term depression
    101127257 (CACNA1A)
   04723 Retrograde endocannabinoid signaling
    101127257 (CACNA1A)
   04721 Synaptic vesicle cycle
    101127257 (CACNA1A)
  09157 Sensory system
   04742 Taste transduction
    101127257 (CACNA1A)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    101127257 (CACNA1A)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    101127257 (CACNA1A)
  09165 Substance dependence
   05032 Morphine addiction
    101127257 (CACNA1A)
   05033 Nicotine addiction
    101127257 (CACNA1A)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101127257 (CACNA1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ggo04040]
    101127257 (CACNA1A)
Ion channels [BR:ggo04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   101127257 (CACNA1A)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel KMS1_N
Other DBs
NCBI-GeneID: 101127257
NCBI-ProteinID: XP_055227551
Ensembl: ENSGGOG00000008660
LinkDB
Position
20:complement(join(19253134..19253859,19254537..19254787,19255087..19255273,19256391..19256426,19257881..19257994,19258162..19258300,19258409..19258518,19260028..19260128,19260296..19260403,19270571..19270676,19274596..19274692,19275980..19276107,19277594..19277744,19280861..19280976,19281149..19281214,19281554..19281670,19291279..19291362,19299071..19299181,19301171..19301335,19303519..19303720,19305724..19305861,19307594..19307754,19308877..19308976,19322050..19322156,19323270..19323329,19329443..19329572,19331243..19331381,19332669..19333132,19344783..19345592,19346787..19346893,19349750..19349826,19349980..19350097,19353965..19354037,19354303..19354434,19354599..19354711,19358838..19358950,19363265..19363474,19376322..19376411,19378949..19379005,19380458..19380573,19381853..19381956,19405559..19405752,19411303..19411455,19417566..19417657,19498417..19498556,19500652..19500757,19551610..19551902))
AA seq 2503 aa
MARFGDEMPARYGGGGSGAAAGVVVGAGGGRGTGGSRQGGQPGAQRMYKQSMAQRARTMA
LYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQH
LPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTG
ILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIF
AIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQ
FDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLS
GEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDAL
RRTTIKKSKTDLLNPEEAEDQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRFYIR
RMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGL
GTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWASLR
NLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAIMTV
FQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQ
ELTKVEADEQEEEEAANQKLALQKAKEVAEVSPLSAANMSIAVKEQQKNQKPAKSVWEQR
TSEMRKQNLLASREALYNEMDPDERWKAAYTRHLRPDMKTHLDRPLVVDPQENRNNNTNK
SRAAEPTVDQRLGQQRAEDFLRKQARYHDRARDPSGSAGLDARRPWAGSQEAELSREGPY
GRESDHHAREGSLEQPGFWEGEAERGKAGDPHRRHVHRQGGSRESRSGSPRTGADGEHRR
HRAHRRPGEEGPEDKVERRARHREGSRPARGGEGEGEGPDGGERRRRHRHGAPATYEGDA
RREDKERRHRRRKENQGSGVPVSGPNLSTTRPIQQDLGRQDPPLAEDIDNMKNNKLATAE
SAVPHGSLGHAGLPQSPAKMGNSTDPGPTPAIPAMATNPQNAASRWTPNNPGNPSNPGPP
KTPENSLIVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKK
EEEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSS
IALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNILDF
IVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVF
NILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVKARDREWKK
YEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSIFYVVYFVVF
PFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMPQNKQSFQYR
MWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLFSLECVLKVM
AFGILNYFRDAWNIFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAARLIKLLRQGYTI
RILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNN
FRTFFQALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLC
SFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHYKDMYSLLRV
ISPPLGLGKKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQ
MDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAMR
EEQDRTPLMFQRMEPPSPTQEGGPGQNALPSTQLDPGGALMAHESGLKESPSWVTQRAQE
MFQKTGTWSPEQGPPTDMPNSQPNSQSVEMREMGRDGYSDSEHYLPMEGQGRAASMPRLP
AENQRRRGRPRGNNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRD
RSHRASERSLGRYTDVDTGLGTDLSMTTQSGDLPSKERDQERGRPKDRKHRQHHHHHHHH
HPPPPDKDRYAQERPDHGRARARDQRWSRSPSEGREHMAHRQGSSSVSGSPAPSTSGTST
PRRGRRQLPQTPSTPRPHVSYSPVIRKAGGSGPPQQQQQQQQAVARPGRAATSGPRRYPG
PTAEPLAGDRPPTGGHSSGRSPRMERRVPGPARSESPRACRHGGARWPASGPHVSEGPPG
PRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPPVRHASSGATGRSPRTPRASGPACA
SPSRHGRRLPNGYYPAHGLARPRGPGSRKGLHEPYSESDDDWC
NT seq 7512 nt   +upstreamnt  +downstreamnt
atggcccgcttcggagacgagatgccggcccgctacgggggaggaggctccggggcagcc
gccggggtggtcgtgggcgccggaggcgggcgaggaaccgggggcagccggcagggcggg
cagcccggggcgcaaaggatgtacaagcagtcaatggcgcagagagcgcggaccatggca
ctctacaaccccatccccgtccgacagaactgcctcacggttaaccggtctctcttcctc
ttcagcgaagacaacgtggtgagaaaatacgccaaaaagatcaccgaatggcctcccttt
gaatatatgattttagccaccatcatagcgaattgcattgtcctcgcactggagcagcat
ctgcctgatgatgacaagaccccgatgtctgaacggctggatgacacagaaccatacttc
attggaattttttgtttcgaggctggaattaaaatcattgcccttgggtttgccttccac
aaaggctcctacttgaggaatggctggaatgtcatggactttgtggtggtgctaacgggc
atcttggcgacagttgggacggagtttgacctacggacgctgagggcagttcgagtgctg
cggccgctcaagctggtgtctggaatcccaagtttacaagtcgtcctgaagtcgatcatg
aaggcgatgatccctttgctgcagatcggcctcctcctattttttgcaatccttattttt
gcaatcatagggttagaattttatatgggaaaatttcataccacctgctttgaagagggg
acagatgacattcagggtgagtctccggctccatgtgggacagaagagcccgcccgcacc
tgccccaatgggaccaaatgtcagccctactgggaagggcccaacaatgggatcactcag
ttcgacaacatcctgtttgcagtgctgactgttttccagtgcataaccatggaagggtgg
actgatctcctctacaatagcaacgatgcctcagggaacacttggaactggttgtacttc
atccccctcatcatcatcggctccttttttatgctgaaccttgtgctgggtgtgctgtca
ggggagtttgccaaagaaagggaacgggtggagaaccggcgggcttttctgaagctgagg
cggcaacagcagattgaacgtgagctcaatgggtacatggagtggatctcaaaagcagaa
gaggtgatcctcgccgaggatgaaactgacggggagcagaggcatccgtttgatgctctg
cggagaaccaccataaagaaaagcaagacagatttgctcaaccccgaagaggctgaggat
cagctggctgatatagcctctgtgggttctcccttcgcccgagccagcattaaaagtgcc
aagctggagaactcaaccttttttcacaaaaaggagaggaggatgcgtttctacatccgc
cgcatggtcaaaactcaggccttctactggactgtactcagtttggtagctctcaacacg
ctgtgtgttgctattgttcactacaaccagcccgagtggctctccgacttcctttactat
gcagaattcattttcttaggactctttatgtccgaaatgtttataaaaatgtacgggctt
gggacacggccttacttccactcttccttcaactgctttgactgtggggttatcattggg
agcatcttcgaggtcatctgggctgtcataaaacctggcacatcctttggaatcagcgtg
ttacgagccctcaggttattgcgtattttcaaagtcacaaagtactgggcatctctcaga
aacctggtcgtctctctcctcaactccatgaagtccatcatcagcctgttgtttctcctt
ttcctgttcattgtcgtctttgcccttttgggaatgcaactcttcggcggccagtttaat
ttcgatgaagggactcctcccaccaacttcgatacttttccagcagcaataatgacggtg
tttcagatcctgacgggcgaagactggaacgaggtcatgtacgacgggatcaagtctcag
gggggcgtgcagggcggcatggtgttctccatctatttcattgtactgacgctctttggg
aactacaccctcctgaatgtgttcttagccatcgctgtggacaatctggccaacgcccag
gagctcaccaaggtggaggcggacgagcaagaggaagaagaagcagccaaccagaaactt
gccctacagaaagccaaggaggtggcagaagtgagtcctctgtccgcggccaacatgtct
atagctgtgaaagagcaacagaagaatcaaaagccagccaagtccgtgtgggagcagcgg
accagtgagatgcgaaagcagaacttgctggccagccgggaggccctgtataacgaaatg
gacccggacgagcgctggaaggctgcctacacccggcacctgcggccagacatgaagacg
cacttggaccggccgctggtggtggacccgcaggagaaccgcaacaacaacaccaacaag
agccgggcggccgagcccaccgtggaccagcgcctcggccagcagcgcgccgaggacttc
ctcaggaaacaggcccgctaccacgatcgggcccgggaccccagcggctcggcgggcctg
gacgcacggaggccctgggcgggaagtcaggaggccgagctgagccgggagggaccctac
ggccgcgagtcggaccaccacgcccgggagggcagcctggagcaacccgggttctgggag
ggcgaggccgagcgaggcaaggccggggacccccaccggaggcacgtgcaccggcagggg
ggcagcagggagagccgcagcgggtccccgcgcacgggcgcggacggggagcaccgacgt
catcgcgcgcaccgcaggcccggggaggagggtccggaggacaaggtggagcggagggcg
cggcaccgcgagggcagccggccggcccggggcggcgagggcgagggcgagggccccgac
gggggcgagcgcaggaggaggcaccggcatggcgctccagccacgtacgagggggacgcg
cggagggaggacaaggagcggaggcatcggaggaggaaagagaaccagggctccggggtc
cctgtgtcgggccccaacctgtcaaccacccggccaatccagcaggacctgggccgccaa
gacccacccctggcagaggatattgacaacatgaagaacaacaagctggccactgcggag
tcggccgttccccacggcagccttggccacgccggcctgccccagagcccagccaagatg
ggaaacagcaccgaccccggccccacgccggccatccccgccatggccaccaacccccag
aatgccgccagccgctggacgcccaacaacccggggaacccatccaatcccggccccccc
aagacccccgagaatagccttatcgtcaccaaccccagcggcacccagaccaattcagct
aagactgccaggaaacccgaccacaccacagtggacatccccccagcctgcccacccccc
ctcaaccacaccgtcgtacaagtgaacaaaaacgccaacccagacccactgccaaaaaaa
gaggaagagaagaaggaggaggaggaagacgaccgtggggaagacggccctaagccaatg
cctccctatagctccatgttcatcctgtccacgaccaacccccttcgccgcctgtgccat
tacatcctgaacctgcgctactttgagatgtgcatcctcatggtcattgccatgagcagc
atcgccctggccgccgaggaccctgtgcagcccaacgcacctcggaacaacgtgctgcga
tattttgactacgtttttacaggcgtctttacctttgagatggtgatcaagatgattgac
ctggggctcgtcctgcatcagggtgcctacttccgtgacctctggaatattctcgacttc
atagtggtcagtggggccctggtagcctttgccttcactggcaatagcaaaggaaaagac
atcaacacgattaaatccctccgagtcctccgggtgctacgacctcttaaaaccatcaag
cggctgccaaagctcaaggctgtgtttgactgtgtggtgaactcgcttaaaaacgtcttc
aacatcctcatcgtctacatgctattcatgttcatcttcgccgtggtggctgtgcagctc
ttcaaggggaaattcttccactgcactgacgagtccaaagagtttgagaaagattgtcga
ggcaaatacctcctctacgagaagaatgaggtgaaggcgcgagatcgggagtggaagaag
tatgaattccattacgacaatgtgctgtgggctctgctgaccctcttcactgtgtccaca
ggagaaggctggccacaggtcctcaagcattcggtggacgccacctttgagaaccagggc
cccagccccggctaccgcatggagatgtccattttctacgttgtctactttgtggtgttc
cccttcttctttgtcaatatctttgtggccttgatcatcatcaccttccaggagcaaggg
gacaagatgatggaggaatacagcctggagaaaaatgagagggcctgcatcgatttcgcc
atcagcgccaagccgctgacccgacacatgccgcagaacaagcagagcttccagtaccgc
atgtggcagttcgtggtgtctccgcctttcgagtacacgatcatggccatgatcgccctc
aacaccatcgtgcttatgatgaagttctatggggcttctgttgcttatgaaaatgccctg
agggtgttcaacatcgtcttcacctccctcttctctctggaatgtgtgctgaaagtcatg
gcttttgggattctgaattatttccgcgatgcctggaacatcttcgactttgtgactgtt
ctgggcagcatcaccgatatcctcgtgactgagtttgggaataacttcatcaacctgagc
tttctccgcctcttccgagctgcccggctcatcaaacttctccgtcagggttacaccatc
cgcattcttctctggacctttgtgcagtccttcaaggccctgccttatgtctgtctgctg
atcgccatgctcttcttcatctatgccatcattgggatgcaggtgtttggtaacattggc
atcgacgtggaggacgaggacagtgatgaagatgagttccaaatcactgagcacaataac
ttccggaccttcttccaggccctcatgcttctcttccggagtgccaccggggaagcttgg
cacaacatcatgctttcctgcctcagcgggaaaccgtgtgataagaactctggcatcctg
actcgagagtgtggcaatgaatttgcttatttttactttgtttccttcatcttcctctgc
tcgtttctgatgctgaatctctttgtcgccgtcatcatggacaactttgagtacctcacc
cgagactcctccatcctgggcccccaccacctggatgagtacgtgcgtgtctgggccgag
tatgaccccgcagcttgcggtcggattcattataaggatatgtacagtttattacgagta
atatctccccctctcggcttaggcaagaaatgtcctcatagggttgcttgcaagcggctt
ctgcggatggacctgcccgtcgcagatgacaacaccgtccacttcaattccaccctcatg
gctctgatccgcacagccctggacatcaagattgccaagggaggagccgacaaacagcag
atggacgctgagctgcggaaggagatgatggcgatttggcccaatctgtcccagaagacg
ctagacctgctggtcacaccccacaagtccacggacctcaccgtggggaagatctacgca
gccatgatgatcatggagtactaccggcagagcaaggccaagaagctgcaggccatgcgc
gaggagcaggaccggacacccctcatgttccagcgcatggagcccccgtccccaacgcag
gaagggggacctggccagaacgccctcccctccacccagctggacccaggaggagccctg
atggctcacgaaagcggcctcaaggagagcccatcctgggtgacccagcgtgcccaggag
atgttccagaagacgggcacatggagtccggaacaaggcccccctaccgacatgcccaac
agccagcctaactctcagtccgtggagatgcgagagatgggcagagatggctactccgac
agcgagcactacctccccatggaaggccagggccgggctgcctccatgccccgcctccct
gcagagaaccagaggagaaggggccggccacgtgggaataacctcagtactatctcagac
accagccccatgaagcgttcagcctccgtgctgggccccaaggcccgacgcctggacgat
tactcgctggagcgggtcccgcccgaggagaaccagcggcaccaccagcggcgccgcgac
cgcagccaccgcgcctctgagcgctccctgggccgctacaccgacgtggacacaggcttg
gggacagacctgagcatgaccacccaatccggggacctgccgtcgaaggagcgggaccag
gagcggggccggcccaaggatcggaagcatcgacagcaccaccaccaccaccaccaccac
caccccccgccccccgacaaggaccgctatgcccaggaacggccggaccacggccgcgca
cgggctcgggaccagcgctggtcccgctcgcccagcgagggccgagagcacatggcgcac
cggcagggcagtagttccgtaagtggaagcccagccccctcaacatctggtaccagcact
ccgcggcggggccgccgccagctcccccagaccccctccaccccccggccacacgtgtcc
tattcccctgtgatccgtaaggccggcggctcggggcccccgcagcagcagcagcagcag
cagcaggcggtggccaggccgggccgggcggccaccagcggccctcggaggtacccaggc
cccacggccgagcctctggccggagatcggccgcccacggggggccacagcagcggccgc
tcgcccaggatggagagacgggtcccaggcccggcccggagcgagtcccccagggcctgt
cgacacggcggggcccggtggccggcatctggcccgcacgtgtccgaggggcccccgggt
ccccggcaccatggctactaccggggctccgactacgatgaggccgatggcccgggcagc
gggggcggcgaggaggccatggccggggcctacgacgcgccaccccccgtacgacacgcg
tcctcgggcgccaccgggcgctcgcccaggactccccgggcctcgggcccggcctgcgcc
tcgccttctcggcacggccggcgactccccaacggctactacccggcgcacggactggcc
aggccccgcgggccgggctccaggaagggcctgcacgaaccctacagcgagagtgacgat
gattggtgctaa

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