KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101127672
Entry
101127672         CDS       T02442                                 
Symbol
LRP5
Name
(RefSeq) low-density lipoprotein receptor-related protein 5
  KO
K03068  low density lipoprotein receptor-related protein 5/6
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04150  mTOR signaling pathway
ggo04310  Wnt signaling pathway
ggo04928  Parathyroid hormone synthesis, secretion and action
ggo05010  Alzheimer disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05200  Pathways in cancer
ggo05224  Breast cancer
ggo05225  Hepatocellular carcinoma
ggo05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101127672 (LRP5)
   04150 mTOR signaling pathway
    101127672 (LRP5)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    101127672 (LRP5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101127672 (LRP5)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101127672 (LRP5)
   05226 Gastric cancer
    101127672 (LRP5)
   05224 Breast cancer
    101127672 (LRP5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101127672 (LRP5)
   05022 Pathways of neurodegeneration - multiple diseases
    101127672 (LRP5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ggo04131]
    101127672 (LRP5)
Membrane trafficking [BR:ggo04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    101127672 (LRP5)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition Ldl_recept_a DUF5050 Vgb_lyase SGL EGF_LRP2 EGF cEGF Insulin_TMD
Other DBs
NCBI-GeneID: 101127672
NCBI-ProteinID: XP_030872107
Ensembl: ENSGGOG00000000038
LinkDB
Position
9:join(76234845..76234926,76269936..76270332,76279431..76279628,76285534..76285730,76287336..76287467,76308402..76308798,76311935..76312106,76325934..76326150,76328819..76329108,76332119..76332345,76333647..76333831,76335917..76336240,76338567..76338766,76345915..76346123,76347528..76347718,76348404..76348613,76352458..76352583,76356467..76356703,76359733..76359843,76361293..76361529,76362623..76362762,76369973..76370070,76372344..76372605)
AA seq 1612 aa
MEAAPPGPPWPLLLLLLALCGCPAPAAASPLLLFANRRDVRLVDAGGVKLESTIVVSGLE
DAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLY
WTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDG
STRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFAL
TLSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEEDN
GGCSHLCLLSPREPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFT
DIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAV
DWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPK
IECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLED
KLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVGTN
PCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETN
NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGM
AVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGK
PRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIAD
DLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGL
NDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDD
QHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSLSQGQNPD
RQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLHGDRDKPRAIIVNAERGYLYF
TNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSG
ANRLTLEDANIVQPLGLTVLGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHA
VEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQ
FACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADC
QDRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAH
SSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPGGS
QHGPFTGIACGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLYPPILNPPPS
PATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASKYY
LDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSPCTDSS
NT seq 4839 nt   +upstreamnt  +downstreamnt
atggaggcagcgccgcccgggccgccgtggccgctgctgctgctgctgctggcgctgtgc
ggctgcccggcccccgccgcggcctcgccgctcctgctatttgccaaccgccgggacgta
cggctggtggacgccggcggagtcaagctggagtccaccatcgtggtcagcggcctggag
gatgcggccgcagtggacttccagttctccaagggagccgtgtactggacagatgtgagc
gaggaggccatcaagcagacctacctgaaccagacgggggccgccgtgcagaacgtggtc
atctccggcctggtctctcccgacggcctcgcctgcgactgggtgggcaagaagctgtac
tggacggactcagagaccaaccgcatcgaggtggccaacctcaatggcacatcccggaag
gtgctcttctggcaggaccttgaccagccgagggccatcgccttggaccccgctcatggg
tacatgtactggacagactggggtgagacaccccggattgagcgggcagggatggatggc
agcacccggaagatcattgtggactcggacatttactggcccaatggactgaccatcgac
ctggaggagcagaagctctactgggctgatgccaagctcagcttcatccaccgtgccaac
ctggacggctcgttccggcagaaggtggtggagggcagcctgacgcacccctttgccctt
acgctctccggggacactctgtactggacagactggcagacccgctccatccatgcctgc
aacaagcgcactggggggaagaggaaggagatcctgagtgccctctactcacccatggac
atccaggtgctgagccaggagcggcagcctttcttccacactcgctgtgaggaggacaat
ggcggctgctcccacctgtgcctgctgtccccaagggagcctttctacacatgcgcctgc
cccacgggtgtgcagctgcaggacaacggcaggacgtgtaaggcaggagccgaggaggtg
ctgctgctggcccggcggacggacctacggaggatctcgctggacacgccggacttcacc
gacatcgtgctgcaggtggacgacatccggcatgccattgccattgactacgacccgcta
gagggctatgtctactggacagatgacgaggtgcgggccatccgcagggcgtacctggac
gggtctggggcgcagacgctggtcaacaccgagatcaacgaccccgatggcatcgcggtc
gactgggtggcccgaaacctctactggaccgacacgggcacggaccgcatcgaggtgacg
cgcctcaacggcacctcccgcaagatcctggtgtcggaggatctggacgagccccgagcc
atcgcactgcaccccgtgatgggcctcatgtactggacagactggggagagaaccctaaa
atcgagtgtgccaacttggacgggcaggagcggcgtgtgctggtcaatgcctccctcggg
tggcccaacggcctggccctggacctgcaggaggggaagctctactggggagacgccaag
acagacaagatcgaggtgatcaatgttgatgggacgaagaggcggaccctcctggaggac
aagctcccgcacattttcgggttcacgctgctgggggacttcatctactggactgactgg
cagcgccgcagcatcgagcgggtgcacaaggtcaaggccagccgggacgtcatcattgac
cagctgcccgacctgatggggctcaaagctgtgaatgtggccaaggtcgtcggaaccaac
ccgtgtgcggacaggaacggggggtgcagccacctgtgcttcttcacaccccacgcaacc
cggtgtggctgccccatcggtctggagctgctgagtgatatgaagacctgcatcgtgcct
gaggccttcttggtcttcaccagcagagccgccatccacaggatctccctcgagaccaat
aacaatgacgtggccatcccgctcacgggcgtcaaggaggcctcagccctggactttgat
gtgtccaacaaccacatctactggacagacgtcagcctgaagaccatcagccgcgccttc
atgaatgggagctcggtggagcatgtggtggaatttggccttgactaccccgagggcatg
gccgttgactggatgggcaagaacctctactgggccgacactgggaccaacagaatcgaa
gtggcgcggctggatgggcagttccggcaagtcctcgtgtggagggacttggacaacccg
aggtcgctggccctggatcccaccaagggctacatctactggaccgagtggggcggcaag
ccgaggatcgtgcgggccttcatggacgggaccaactgcatgacgctggtggacaaggtg
ggccgggccaacgacctcaccattgactacgctgaccagcgcctctactggaccgacctg
gacaccaacatgatcgagtcgtccaacatgctgggtcaggagcgggtcgtgattgccgac
gacctcccgcacccattcggtctgacacagtacagcgattatatctactggacggactgg
aatctgcacagcattgagcgggccgacaagactagcggccggaaccgcaccctcatccag
ggccacctggactttgtgatggacatcctggtgttccactcctcccgccaggatggcctc
aatgactgtatgcacaacaacgggcagtgtgggcagctgtgccttgccatccccggcggc
caccgctgcggctgcgcctcacactacaccctggaccccagcagccgcaactgcagcccg
cccaccaccttcttgctgttcagccagaaatctgccatcagtcggatgatcccggacgac
cagcacagcccggatctcatcctgcccctgcatggactgaggaacgtcaaagccatcgac
tatgacccactggacaagttcatctactgggtggatgggcgccagaacatcaagcgagcc
aaggacgacgggacccagccctttgttttgacctctctgagccaaggccaaaacccagac
aggcagccccacgacctcagcatcgacatctacagccggacactgttctggacgtgcgag
gccaccaataccatcaacgtccacaggctgagcggggaagccatgggggtggtgctgcat
ggggaccgcgacaagcccagggccatcatcgtcaacgcggagcgagggtacctgtacttc
accaacatgcaggaccgggcagccaagatcgaacgcgcagccctggatggcaccgagcgc
gaggtcctcttcaccactggcctcatccgccctgtggccctggtggtggacaacacactg
ggcaagctgttctgggtggacgcggacctgaagcgcattgagagctgtgacctgtcaggg
gccaaccgcctgaccctggaggacgccaacatcgtgcagcctctgggcctgaccgtcctt
ggcaagcacctctactggatcgaccgccagcagcagatgatcgagcgtgtggagaagacc
accggggacaagcggactcgcatccagggccgtgtcgcccacctcactggcatccatgcg
gtggaggaagtcagcctggaggagttctcagcccatccatgtgcccgtgacaatggtggc
tgctcccacatctgtattgccaagggtgatgggacaccacggtgctcatgcccagtccac
ctcgtgctcctgcagaacctgctgacctgtggagagccgcccacctgctccccggaccag
tttgcatgtgccacaggggagatcgactgtatccccggggcctggcgctgtgacggcttt
cccgagtgcgacgaccagagcgacgaggagggctgccccgtgtgctccgccgcccagttc
ccctgcgcgcggggccagtgtgtggacctgcgcctgcgctgcgacggcgaggcagactgt
caggaccgctcagacgaggcggactgtgatgccatctgcctgcccaaccagttccggtgt
gcgagcggccagtgtgtcctcatcaaacagcagtgcgactccttccccgactgtatcgac
ggctccgacgagctcatgtgtgaaatcaccaagccgccctcagacgacagcccggcccac
agcagtgccatcgggcccgtcattggcatcatcctctctctcttcgtcatgggtggtgtc
tattttgtgtgccagcgcgtggtgtgccagcgctatgccggggccaacgggcccttcccg
cacgagtatgtcagcgggaccccgcacgtgcccctcaatttcatagccccgggcggttcc
cagcatggccccttcacaggcatcgcatgcggaaagtccatgatgagctccgtgagcctg
atggggggccggggcggggtgcccctctacgaccggaaccacgtcacaggggcctcgtcc
agcagctcgtccagcacgaaggccacactgtacccgccgatcctgaacccgccgccctcc
ccggccacggacccctccctgtacaacatggacatgttctactcttcaaacattccggcc
actgcgagaccgtacaggccctacatcattcgaggaatggcgcccccgacgacgccctgc
agcaccgacgtgtgtgacagcgactacagcgccagccgctggaaggccagcaagtactac
ctggatttgaactcggactcagacccctacccgcccccacccacgccccacagccagtac
ctgtcggcggaggacagctgcccgccctcgcccgccaccgagaggagctacttccatctc
ttcccgccccctccgtccccctgcacggactcatcctga

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