KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101128119
Entry
101128119         CDS       T02442                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00230  Purine metabolism
ggo01100  Metabolic pathways
ggo04024  cAMP signaling pathway
ggo05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101128119 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    101128119 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    101128119 (PDE10A)
Enzymes [BR:ggo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     101128119 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     101128119 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 101128119
NCBI-ProteinID: XP_030868377
Ensembl: ENSGGOG00000003914
LinkDB
Position
5:complement(join(189649857..189649959,189652866..189652954,189655691..189655771,189659636..189659747,189695431..189695603,189704515..189704670,189708850..189709000,189711378..189711461,189712518..189712660,189727761..189727947,189730467..189730559,189732912..189733054,189742916..189742967,189744552..189744610,189745687..189745737,189747228..189747383,189749173..189749313,189762858..189762907,189764177..189764297,189796394..189796422,189857387..189857515,189980038..189980905))
AA seq 1056 aa
MASLEEPLAPRPQGPLPAAGDEPGCGPGKLRPEPRLSAAGGGSAAGPGPAPEWPGRGRAE
RAAPPRPPPSSAGRPSTAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSFFYFWP
PPPPPPPSFLPSSSAFHLPVRLPGREGAAAAAAAGGGGDAGGGGGGGGQEAAPLSVPTSS
SHRGGGGSGGGRRRLFLSPALQGLLLPARAGPRPPPPPRLPLGQAARRAGSPGFPGAGPG
GGGQTPRRPQGASFALAAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKAYL
SLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIE
QRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAG
PITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGI
LELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDN
IVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIR
FSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQ
MVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTS
EEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIM
SVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNS
YLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIAT
DLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIY
AEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLK
ACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
NT seq 3171 nt   +upstreamnt  +downstreamnt
atggccagcctcgaggagcctcttgctccccgcccccagggtcccctgccagcggccggg
gacgagccgggctgcggccccggcaaactccgcccggaaccccggctcagcgcggccggc
ggggggagcgcggcgggcccgggcccggcccccgagtggcctggccgtggccgggcggag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgccccagcaccgctgggggc
cccggcgccctctctgcgcgcggcggcggctgcggctgggtcgcggcccgcgctcccttg
gcgctcgccttctcctcccgggtcccctcctcctctccatctttcttttacttctggccg
ccgccccccccgccccctccctcttttctcccctcctcatctgcctttcacctccccgtg
cgtctcccaggaagggagggcgcagcggcggcggcggcggcgggaggaggcggcgatgct
ggcggaggaggaggaggaggaggacaagaggcagctcccttgagcgtccccaccagcagt
agtcaccgcggcggcggtggcagcggcggcgggcggcggcggctcttcctctcgcctgcg
ctccagggcttgctgcttccagcccgtgccggtccccggccgccgccgccgccccggctc
ccccttggccaggccgcccgccgcgcgggctcccccggcttccccggcgccggcccaggc
ggcggcggccaaactccgcggcgtccccagggcgccagcttcgccctcgccgccgcggcc
gcgctgctcttcggctccgacatggaagatggaccttctaataatgcgagctgcttccga
aggctgaccgagtgcttcctgagccccagtttgacagatgaaaaagtgaaggcatatctt
tctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagagacagta
gagaaatggctgaagaggaagaacaacaaatcagaagatgaatcggctcctaaggaagtc
agcaggtaccaagatacgaatatgcagggagttgtatatgaactaaacagctatatagaa
caacggttggacacaggaggagacaaccagctactcctctatgaactgagcagcatcatt
aaaatagccacaaaagccgatggatttgcactgtatttccttggagagtgcaataatagc
ctgtgcatattcacaccacctgggataaaggaaggaaaaccccgcctcatccctgctggg
cccatcactcagggcaccaccgtctctgcttatgtggccaagtccaggaagacactgcta
gtagaagacatccttggagatgaacgatttccaagaggtactggactggaatcagggact
cgtatccagtctgttctttgcttgccaattgtcactgcaattggtgacttgattggtatt
ctcgagctgtatcggcactggggcaaagaagccttctgtcttagtcaccaggaggttgca
acagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcagaggcctt
gccaaacagacagaattgaatgacttcctactcgacgtatcaaaaacgtattttgataac
atagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctggtgaat
gccgatcgttgtgcacttttccaggtagaccataagaacaaggagttgtattcagacctt
tttgatattggagaggaaaaggaaggaaaacctgtcttcaagaagaccaaagagataaga
ttttcaattgagaaaggaattgctggccaagtagcaagaacaggggaagtcctgaacatt
ccagatgcctatgcagacccacgctttaacagagaagtagacttgtacacaggctacacc
acgcggaacatcctgtgcatgcccatcgtcagccgaggcagcgtgataggtgtggtgcag
atggtcaacaaaatcagtggcagtgccttctctaaaacagatgaaaacaacttcaaaatg
tttgccgtcttttgtgctttagccttacactgtgctaatatgtatcatagaattcgccac
tcagagtgcatttaccgggtaacgatggaaaagctgtcctaccatagcatttgtacttca
gaagagtggcaaggcctcatgcaattcacccttcccgtgcgtctctgcaaagaaattgaa
ttattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtctacatg
gttcatcggtcctgtgggacatcctgctttgagcttgaaaagttgtgtcgttttattatg
tctgtgaagaagaactatcggcgggttccttatcacaactggaagcatgcggtcactgta
gcacactgcatgtatgccatacttcagaacaatcacacgcttttcacagaccttgagcgc
aaaggactgctgattgcgtgtctgtgtcatgacctggaccacaggggcttcagtaacagc
tacctgcagaagttcgaccaccctctggctgctctctactccacttccaccatggagcag
caccacttctcccagaccgtgtccatcctccagttggaagggcacaatatcttctccact
ctgagctccagtgaatatgagcaggtgcttgagatcatccgcaaagccatcattgccaca
gaccttgctttatactttggaaacaggaagcagttggaagagatgtaccagaccggatca
ctaaaccttaataatcaatcacatagagaccgtgtaattggtttgatgatgactgcctgt
gacctttgttctgtgacaaaactgtggcccgttacaaaattgacggcaaatgatatatat
gcagaattctgggctgagggtgatgaaatgaagaaattgggaatacagcctattcctatg
atggacagagacaagaaggatgaagtcccccaaggccagcttgggttctacaatgccgtg
gccattccctgctatacaacccttacccagatcctccctcccacggagcctcttctgaaa
gcatgcagggataatctcagtcagtgggagaaggtgattcgaggggaggagactgcaacc
tggatttcatccccatccgtggctcagaaggcagctgcatctgaagattga

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