KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101130129
Entry
101130129         CDS       T02442                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04310  Wnt signaling pathway
ggo04390  Hippo signaling pathway
ggo04550  Signaling pathways regulating pluripotency of stem cells
ggo04810  Regulation of actin cytoskeleton
ggo04934  Cushing syndrome
ggo05010  Alzheimer disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05165  Human papillomavirus infection
ggo05200  Pathways in cancer
ggo05206  MicroRNAs in cancer
ggo05210  Colorectal cancer
ggo05213  Endometrial cancer
ggo05217  Basal cell carcinoma
ggo05224  Breast cancer
ggo05225  Hepatocellular carcinoma
ggo05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101130129 (APC2)
   04390 Hippo signaling pathway
    101130129 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101130129 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101130129 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101130129 (APC2)
   05206 MicroRNAs in cancer
    101130129 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101130129 (APC2)
   05225 Hepatocellular carcinoma
    101130129 (APC2)
   05226 Gastric cancer
    101130129 (APC2)
   05217 Basal cell carcinoma
    101130129 (APC2)
   05213 Endometrial cancer
    101130129 (APC2)
   05224 Breast cancer
    101130129 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101130129 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101130129 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    101130129 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101130129 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ggo01009]
    101130129 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ggo03036]
    101130129 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:ggo04812]
    101130129 (APC2)
Protein phosphatases and associated proteins [BR:ggo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101130129 (APC2)
Chromosome and associated proteins [BR:ggo03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    101130129 (APC2)
Cytoskeleton proteins [BR:ggo04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     101130129 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC APC_r Arm Arm_APC_u3 Suppressor_APC SAMP ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS bZIP_1 PDC10_C HALZ CCDC138_cc
Other DBs
NCBI-GeneID: 101130129
NCBI-ProteinID: XP_030862579
Ensembl: ENSGGOG00000002822
LinkDB
Position
20:join(7234480..7234911,7235576..7235734,7235827..7235917,7236011..7236191,7237733..7237841,7237968..7238084,7238697..7238774,7238939..7239037,7239488..7239878,7240611..7240706,7242825..7242964,7243424..7243501,7243681..7243797,7244606..7244820,7247832..7252890)
AA seq 2453 aa
MRGHLGVREQMTGEYMCVARWRREGRSRWAGQGRCEEGAQAGRGRWQRDGLPLVRLRQRR
REEASADGKGTKREGGREGGLRREGRAEGGGAGQLDRGRRPGRSQKTARGTKKPAALAES
TDGAGAAGASRDQLKAAQGVRATQTLQELKMASSVAPYEQLVRQVEALKAENSHLRQELR
DNSSHLSKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLK
FQPPTLGPEPAARTPEGSPVHGSGHSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEK
EKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQ
RAQIRASRLEQIDKELLEAQDRVQQTEPQALLAVKSVPVDEDPETEVPTHPEDGTPQPGN
SKVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAAVGG
RAGAPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQA
RDGGPEGGSAGSAPIPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEM
HKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASDSEELHQVVS
SILRNLSWRADINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWNLSAHSTENKAA
ICQVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTL
LQHLTSHSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAA
LRNLLAHRPAKHQAAATAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKQGPPAA
EAATKKPLPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALSLFLGSPF
LQGQALARTPPTRREGKEAEKVTSGEAAVAAKAKAKLALAVARIDQLVEDISALHTSSDD
SFSLSSGDPGQEAPREGRAQSCSPCRGPEGGRREAGSRAHPLLRLKAAHASLSNDSLNSG
SASDGYCPREHMLPCPLAALASRREDPRCGQPRPSRLDLDLPGGQAEPPARDATSADARV
RTIKLSPTYQHVPLLEGASRAGAEPLAGPGTSPGARKQAWLPADHLSKVPEKLAAAPLSV
ASKALQKLAAQEGPLSLSRCSSLSSLSSAGRPGPSEGGDLDDSDSSLEGLEEAGPSEAEL
DSAWRAPGATSLPVAIPAPRRNRGRGLGVEDATPSSSSENYVQETPLVLSRCSSVSSLGS
FESPSIASSIPSDPCSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQGPPEATQFS
LQWESYVKRFLDIADCRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALHEHYVQQ
DVELRLLPSACPERGGGAGGAGLHFAGHRRREEGPAPTGSRPRGAADQELELLRECLGAA
VPARLRKVASALVPGRRALPVPVYMLVPAPAPAQEDDSCTDSAEGTPVNFSSAASLSDET
LQGPPRDQPGGPAGKQRPTGRPTSARQAVGHRHKAGGAGRSAEQSRGAGKNRAGLELPLG
RPASAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRT
SAIPRAFTRERPQGRKEAPAPSKAVPAAPPPARTQPSLIADETPPCYSLSSSASSLSEPE
PSEPPAVHPRGREPAVTKHPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRR
KPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREA
SSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAG
PEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPA
KVPSPGQQRSRSLHRPGKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKR
PPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPE
PGPRGRAGTEVGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSE
LSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQAPAPARQRTPAARPGPGE
RPARRTSSESPSRLPVRAPATRPETVKRYASLPHISVARRPDGAVPAAPAPADAARRSSD
GEPRPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAV
VQTEEVAATKTNSSTSPSLETREPPGAPAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLG
VAVGGFPASRHGSPSRSARVPPFNYVPSPMVVAATTDSAAEKAPATASATLLE
NT seq 7362 nt   +upstreamnt  +downstreamnt
atgagggggcacctgggggtcagagaacaaatgacgggtgaatacatgtgtgtggccagg
tggaggagggaggggaggagcaggtgggccggacagggccggtgtgaggagggggctcag
gctggcagggggaggtggcagagggatgggctgccattggtgcgtctgagacaaaggcgg
agggaggaggcgagcgctgatgggaaaggaacaaagagggaaggggggcgtgaagggggg
ctccggcgggagggccgagccgagggaggaggcgccggccagctggacagagggaggagg
ccaggccggagccagaagacggccagaggcacaaagaagccagcggcactggcagagtca
acggatggggcaggggctgccggggccagcagggaccagctgaaggctgcgcagggggtg
cgggccacacagacgctgcaggagctgaagatggcgagctccgtggcgccctacgagcag
ctggtacggcaggtggaggccttgaaggctgagaacagccacctgaggcaggagctaagg
gacaactccagccacctatccaagctggagacagagacgtcgggcatgaaggaggtcctg
aagcacctacagggaaaactggagcaggaggcccgagtgctggtgtcctcggggcagacg
gaggtgctggagcagctgaaggccctacagatggacatcaccagcctgtacaacctcaag
ttccagccgcccaccctgggcccggagcctgccgcccggacccccgagggcagcccagta
cacggctccgggcactccaaggacagctttggggagctgagccgggccaccatccggctg
ctggaggaactggaccgggaacggtgtttcctgctgaatgagattgagaaggaggagaag
gagaagctctggtactactctcagctgcagggcctgtccaagcgcctggacgagctgccg
cacgtggagacgcagttctcgatgcagatggacctgatccggcagcagcttgagttcgag
gcccagcacatccgctcgctgatggaggagcgcttcggcacctcggacgagatggtgcag
cgggcacagatccgcgcctcgcgcctggagcagattgacaaggagctgctggaggcgcag
gaccgagtgcagcagacggagccccaggccttgctggcggtgaagtccgtgccggtggac
gaggaccccgagacagaggtccccacacaccctgaggatggcacccctcagccgggcaac
agcaaggtggaggtggtcttctggctgttgtccatgttggcgacgcgcgaccaggaggat
acagcgcgcacgctgctggccatgtccagctcgcccgagagctgcgtggccatgcgccgc
tcgggctgtctgcctctgctgctgcaaatcctccacggcaccgaggctgcggtcgggggt
cgtgccggggccccaggagcaccgggcgccaaggacgcacgcatgcgcgccaacgcggcg
ctgcacaacatcgtcttctcgcagccggaccagggcctggcgcgcaaggagatgcgcgtc
ctgcacgtgctggagcagatccgggcctactgcgagacctgctgggactggctgcaggcc
cgagacggcgggcctgagggaggcagcgccggcagcgccccgatccccattgagccgcag
atctgccaggccacctgtgctgttatgaagctgtcctttgacgaggagtaccgccgtgcc
atgaacgagctaggtgggctgcaggccgtggcagagctgctgcaggttgactatgagatg
cacaagatgacccgggacccgctgaacctggcactgcgccgctacgcgggcatgaccctc
accaacctcacctttggggacgttgccaacaaggccaccctgtgtgcgcgccgcggctgc
atggaggccatcgtggcccagctggcctccgacagtgaggagctccaccaggtggtgtcc
agcatccttcggaacttgtcctggagggccgacatcaacagcaagaaggtgctgagggag
gcgggcagcgtgactgccctggtgcagtgtgtcctgcgggccaccaaggagtccaccctg
aagagcgtgctgagcgctctgtggaatctgtctgcacacagcacagagaacaaggcggcc
atctgccaggtggatggcgccctgggcttcctggtgagcaccctgacctacaagtgtcag
agcaactcgctggccatcatcgagagcggcggcggcatcctccgcaatgtgtccagcctc
atcgccacccgtgaggactacaggcaggtgctccgggatcacaactgtctgcagacgctg
ctgcagcatctgacttcgcacagcctgaccatcgtgagcaacgcgtgcggcacgctctgg
aacctgtcggcccgcagcgcccgtgaccaggagctgctgtgggacctgggcgccgtgggc
atgctgcgtaatctggtgcactccaagcacaagatgatcgccatgggcagcgccgccgcc
ctgcgcaacctgctggcccatcggcccgccaagcaccaggcggccgccaccgccgtgtcc
ccaggcagctgcgtgcccagcctgtacgtgcgcaagcagcgggcgctggaggccgagctg
gacgcacggcacctcgcgcaggcgctggagcacctggagaagcagggcccgccggcagcc
gaggccgccactaagaagccgctgccgcccctgcgacacctggacggcctggcccaagac
tatgcttccgattcgggctgctttgacgacgacgatgcaccgtcatccctggctgcggcc
gcggccaccggggagccagccagccctgccgcgctgtccctcttcctgggcagccccttc
ctgcaggggcaggcgctggctcgcaccccgcccacccgccgagaaggcaaggaggcagag
aaggtcaccagtggggaggcagccgtggcggccaaggccaaggccaagctggcgcttgca
gtggcgcgcatcgaccagctggtggaggacatctccgccctgcacacctcgtccgacgat
agcttcagcctcagctctggagacccggggcaggaggcgccacgggagggccgcgcccag
tcctgctcgccatgccgcggcccggagggcgggcggcgagaggcaggaagccgggcgcac
ccgctgctgaggctcaaggcggcccacgccagcctctccaacgacagcctcaacagcggc
agtgccagcgacgggtactgcccacgcgaacatatgctgccctgcccgctggccgcactg
gcttcgcgccgcgaggaccccaggtgtgggcagccccggcccagccggcttgaccttgac
ctgcccggcggccaggccgagccccccgcccgcgatgccacatccgccgacgcccgcgtg
cgcaccatcaagctgtcgcctacctatcagcacgtgccactgcttgagggtgcctcaagg
gcgggtgcagagcccctcgcggggcctggaacctctccaggggcccggaagcaggcctgg
ctgccggcagaccacctgagcaaggttcccgagaagctggcggccgccccgctgtctgtg
gccagcaaggcactgcagaaactggcggcgcaagaggggccgctctcgctgtcccgatgc
agctccctttcctcgctgtcctcggccggccgcccaggccccagcgagggcggtgacctg
gatgacagtgattcctccctggaggggctggaggaggccggccccagcgaggctgagctg
gacagcgcgtggcgggcgcccggggccacctcgctgcccgtagccattccggctccccgg
cgtaaccgaggccggggcctgggggtggaagacgccacgccgtccagctcgtcggagaac
tacgtgcaggagacaccgcttgtgctgagccgctgcagctctgtgagctcactgggcagc
ttcgagagcccgtccatcgccagctccatccccagtgacccttgcagcgggcagggcagc
ggcaccatcagccctagcgagctgcccgacagccccggacagaccatgcctcccagccgg
agcaagacgccaccgctggcgcccgcgccacagggtccccccgaggccacccagttcagc
ctgcagtgggagagctacgtgaagcgcttcctggacatcgccgactgccgggagcgctgc
cggctgccatctgagctggacgcaggcagcgtgcgctttaccgtggagaagccagacgag
aacttctcatgcgcctccagcctcagcgcgctggccttgcacgagcactacgtgcagcag
gacgtggagctgcggctgctgccctcggcctgcccggagcgcggcgggggcgccgggggc
gccggcctccactttgcagggcaccggcggcgggaggaagggccggcgcccacgggttct
cgccctcgcggcgccgcggaccaggagctggaactgctgcgggagtgcctgggagccgcc
gtgcctgcccggctgcgcaaggtggcctccgcgctggtgccaggtcgccgcgcactcccc
gtgcccgtctacatgttggtgcccgccccggccccggcccaggaggacgactcctgcact
gactccgcggagggcacgccggtcaacttctctagcgctgcctcgctcagcgacgagacg
ctgcagggaccccccagggaccagcccgggggaccagcgggcaagcaaagacccaccggc
cgccccacctctgccaggcaggccgtggggcaccggcacaaagcgggaggcgccggccgc
agcgcggagcagtctcggggcgcgggcaagaaccgagcagggctggagctgcccctgggc
cgccccgcgagcgcccccgcagacaaggacggctccaagcccggccggacccgcggggac
ggggcgcttcagtcgctgtgtctcacgacgcccactgaggaggccgtgtactgcttctat
ggcaacgactcggacgaggagcccccggcggccgcgcccacgcccacccaccggcgcaca
tcggccatccctcgcgcttttacgcgggagcgtccgcagggccggaaggaggcccctgcc
ccgtccaaggctgtaccagccgccccgccgcccgcccggacccagcccagcctcattgct
gacgagaccccgccctgctactccctgagctcctccgccagctccctcagcgagcccgag
ccctcggagccgccggccgtccatccacgaggccgggagcccgcggtcaccaagcacccg
ggcccaggaggcggacgcgacagctcgcccagcccgcgggccgcggaggagcttctgcag
cggtgcatcagctcggccctgcccaggcgccggccccccgtgtctggcctgcggcgccgc
aagccccgagccacccgtttggatgagcggcccgcagaggggtcccgggaacgcggcgag
gaggcagcgggctcggaccgggcctccgacctggatagcgtggagtggcgcgccatccag
gagggcgccaattcaattgtcacgtggctgcaccaggcagcagctgccacgcgggaggcc
tcgtccgagtccgactccatcctgtccttcgtatccgggctgtcggtggggtccacccta
cagccccccaagcacaggaagggacgacaggcggagggagaaatgggcagtgcccggcgg
ccagagaaaaggggcgcagcctcagtcaagaccagcgggagcccccgttcccctgcaggc
cccgagaagccacgtggcacacagaagaccacgcccggggtgccagctgtgctccgggga
cgaacagtgatctacgtccccagcccggcaccccgtgcccagcccaaagggacccccggc
ccccgcgccacaccgcggaaggtggcgcccccttgcctggcacagcccgcagctccagcc
aaagtcccgagccccgggcagcagcggtcgcggagcctacaccggcctggcaagacctcg
gagctggcgacgctgagccagccccccagaagcgccacaccgcccgcccgcctcgccaag
accccctcctccagctcctcccagacctcgcccgcctcccagcccctgcccagaaagcgc
cccccggtcacccaggctgctggggccctgcccggccccggagcctccccggtgcccaag
acgccggcgcgcacccttctggcgaagcagcacaagacgcagagatcgcccgtgcggatc
ccgttcatgcagaggccggcccggcgtgggccgccaccgctggctcgggcagtcccggag
ccgggccccaggggccgggcggggaccgaggtgggcccgggggcgcgtgggggccgcctg
ggcctggtgcgtgtggcctcagccctctccagcggcagcgagtcctccgaccgctcgggc
ttccggcgacagctgaccttcatcaaggagtcgccgggcttgcggcgccgccgctccgag
ctgtcctcggccgagtccgctgcctctgccccccagggcgcctcgccccgccgcggccgg
cccgcgctgcccgccgtcttcctctgctcctcgcgctgcgaagagctccgagcggcaccc
cggcaggccccggccccggcccggcagcggacccccgcggcccgacccggccctggcgag
cgccctgcccggcgcaccagctccgagagcccgtcccgcctgcctgtgcgcgcgcccgcc
acccggccggagactgtcaagcgctacgcgtcgctgccccacatcagcgtggcccgcagg
cccgacggcgccgtccccgcggcccctgccccagccgacgccgcgcgccgcagcagcgac
ggggagccccggccgctccccagggtggccgcgccgggcacgacgtggcggcgcatccga
gatgaggacgtgccccacatcctgcgcagcacgctgcccgccacggccctgccactgcgg
ggctccacgcccgaggacgccccggccgggcccccgccgcgcaagaccagcgacgccgtg
gtccagaccgaggaggtcgccgccaccaagaccaactccagcacgtccccgagcctggag
accagggagccccccggggcccccgccggcggccagctctccctcctcggcagcgacgtg
gacggtcccagcctcgccaaggctcccatctccgcacccttcgtgcacgagggcctgggg
gtcgccgtggggggcttccccgccagccggcacggctcccccagccgctcggcccgagta
ccccccttcaactatgtgcccagccccatggtggtcgcagccaccaccgactcggccgcg
gagaaagccccggccactgcctccgccaccctcctggaatag

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