KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101133630
Entry
101133630         CDS       T02442                                 
Symbol
USP8
Name
(RefSeq) ubiquitin carboxyl-terminal hydrolase 8 isoform X1
  KO
K11839  ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04137  Mitophagy - animal
ggo04144  Endocytosis
ggo04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101133630 (USP8)
   04137 Mitophagy - animal
    101133630 (USP8)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101133630 (USP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ggo01002]
    101133630 (USP8)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ggo04131]
    101133630 (USP8)
   04121 Ubiquitin system [BR:ggo04121]
    101133630 (USP8)
Enzymes [BR:ggo01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     101133630 (USP8)
Peptidases and inhibitors [BR:ggo01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   101133630 (USP8)
Membrane trafficking [BR:ggo04131]
 Endosome - Lysosome transport
  Others
   Others
    101133630 (USP8)
Ubiquitin system [BR:ggo04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    101133630 (USP8)
SSDB
Motif
Pfam: UCH USP8_dimer WW_USP8 UCH_1 Rhodanese Metallothio_Pro HscB_4_cys GAP45
Other DBs
NCBI-GeneID: 101133630
NCBI-ProteinID: XP_018866628
Ensembl: ENSGGOG00000024945
UniProt: G3S984
LinkDB
Position
16:join(51223893..51223996,51226193..51226337,51234216..51234301,51243754..51243916,51247050..51247092,51249810..51249954,51256386..51256548,51261562..51261706,51261989..51262212,51266184..51266768,51268980..51269066,51274441..51274521,51274905..51275167,51277348..51277560,51278714..51278924,51280508..51280744,51281780..51281922,51283287..51283419,51283590..51283775)
AA seq 1118 aa
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK
KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSSGEKNEKCETKEK
GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP
DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG
YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQMPPASIEVDE
NIELISDQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE
HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK
ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET
SSKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEVQKKSTGDVPHTSVTGDSGSG
KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD
PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP
DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR
NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG
QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH
LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS
KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW
KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW
FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT
NT seq 3357 nt   +upstreamnt  +downstreamnt
atgcctgctgtggcttcagttcctaaagaactctacctcagttcttcactaaaagacctc
aataagaagacagaagttaaaccagagaaaataagcactaagagttatgtgcacagtgcc
ctgaagatctttaagacagcagaagaatgcagattagatcgtgatgaggaaagggcctat
gtactatatatgaaatacgtgactgtttataatcttatcaaaaaaagacctgatttcaag
caacagcaggattatttccattcaatacttggacctggaaacatcaaaaaagctgtcgaa
gaagctgaaagactctctgaaagccttaaattaagatatgaagaagctgaagtccggaaa
aaacttgaggaaaaagacaggcaggaggaagcacagcggctgcaacaaaaaaggcaggaa
acaggaagagaggatggtggcacattggctaaaggttctttggagaatgttttggattcc
aaagacaaaacccaaaagagcagtggtgaaaagaatgaaaaatgtgagaccaaagagaaa
ggagcaatcacagcaaaggaactatacacaatgatgacggataaaaacatcagcttgatt
ataatggatgctcgaagaatgcaggattatcaagattcctgtattttacattctctcagt
gttcctgaagaagccatcagtccaggagtcactgctagttggattgaagcacacctgcca
gatgattctaaagacacatggaagaagagggggaatgtggagtatgtggtacttcttgac
tggtttagttctgccaaagatttacagattggaacaactctccggagtctgaaagatgca
cttttcaagtgggaaagtaaaactgtcctgcgcaatgagcctttggttttagagggaggc
tatgaaaactggctcctttgttatccccagtatacaacaaatgctaaggtcactccaccc
ccacgacgccagaatgaagaggtgtctatctcattggattttacttatccctcattggaa
gaatcaattccttctaaacctgctgcccagatgccacctgcatctatagaagtagatgaa
aatatagaattgataagtgatcaaaatgagagaatgggaccactgaatatatcaactcca
gttgaaccagttgctgcttctaaatctgatgtttcacccataattcagccagtgcctagt
ataaagaatgttccacagattgatcgtactaaaaaaccagcagtcaaattgcctgaagag
catagaataaaatctgaaagtacaaaccatgagcaacaatctcctcagagtggaaaagtt
attcctgatcgttccaccaagccagtagttttttctccaactctcatgttaacagatgaa
gaaaaggctcgtattcatgcagaaactgctcttctaatggaaaaaaacaaacaagaaaaa
gaacttcgggaaaggcagcaagaggaacagaaagagaaactgaggaaggaagaacaagaa
caaaaagccaaaaagaaacaagaagctgaagaaaatgaaattacagagaagcaacaaaaa
gcaaaagaagaaatggagaagaaagaaagtgaacaggccaagaaagaagataaagaaacc
tcatcaaagaggggcaaagaaataacaggagtaaaaagacaaagtaaaagtgaacatgaa
acttctgatgccaagaaatctgtagaagatagggggaaaaggtgtccaaccccagaagta
cagaaaaagtcaacaggagatgtgccccatacatctgtgacaggggattcaggttcaggc
aagccatttaagattaaaggacaaccagaaagtggaattctaaggacaggaacttttaga
gaggatacagacgataccgaaagaaataaagctcaacgagaacctttgacaagagcacga
agtgaagaaatggggaggatcgtaccaggactgccttcaggctgggccaagtttcttgac
ccaatcactggaacctttcgttattatcattcacccaccaacactgttcatatgtaccca
ccggaaatggctccttcatctgcacctccttccacccctccaactcataaagccaagcca
cagattcctgctgagcgggatagggaaccttccaaactgaagcgctcctactcctcccca
gatataacccaggctattcaagaggaagagaagaggaagccaacagtaactccaacagtt
aatcgggaaaacaagccaacatgttatcctaaagctgagatctcaaggctttctgcttct
cagattcggaacctcaatcctgtttttggaggttctggaccagctcttactggacttcgt
aacttaggaaatacttgttatatgaactcaatattgcagtgcctatgtaacgctccacat
ttggctgattatttcaaccgaaactgttatcaggatgatattaacaggtcaaatttgttg
gggcataaaggtgaagtggcagaagaatttggtataatcatgaaagccctgtggacagga
cagtatagatatatcagtccaaaggactttaaaatcaccattgggaagatcaatgaccag
tttgcaggatacagtcagcaagattcacaagaattgcttctgttcctaatggatggtctc
catgaagatctaaataaagctgataatcggaagagatataaagaagaaaataatgatcat
ctcgatgactttaaagctgcagaacatgcctggcagaaacacaagcagctcaatgagtct
attattgttgcactttttcagggtcaattcaaatctacggtacagtgcctcacatgtcac
aaaaagtctaggacatttgaggccttcatgtatttgtctctaccactagcatccacaagt
aaatgtacattacaggattgccttagattattttccaaagaagaaaaactcacagataac
aacagattttactgcagtcattgcagagctcgacgggattctctaaaaaagatagaaatc
tggaagttaccacctgtgcttttagtgcatctgaaacgtttttcctacgatggcaggtgg
aaacaaaaattacagacatctgtggacttcccgttagaaaatcttgacttgtcacagtat
gttattggtccaaagaacaatttgaagaaatataatttgttttctgtttcaaatcactac
ggcgggctggatggaggccactacacagcctattgtaaaaatgcagcaagacaacggtgg
tttaagtttgatgatcatgaagtttctgatatctccgtttcttctgtgaaatcttcagca
gcttatatcctcttttatacttcattgggaccacgagtaactgatgtagccacataa

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