KEGG T02442: 101134255

Gorilla gorilla gorilla (western lowland gorilla): 101134255

Entry

101134255         CDS       T02442

Symbol

ITGA8

Name

(RefSeq) integrin alpha-8 isoform X1

K06584

integrin alpha 8

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo04151

PI3K-Akt signaling pathway

ggo04510

Focal adhesion

ggo04512

ECM-receptor interaction

ggo04514

Cell adhesion molecules

ggo04810

Regulation of actin cytoskeleton

ggo04820

Cytoskeleton in muscle cells

ggo05165

Human papillomavirus infection

ggo05410

Hypertrophic cardiomyopathy

ggo05412

Arrhythmogenic right ventricular cardiomyopathy

ggo05414

Dilated cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ggo00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101134255 (ITGA8)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    101134255 (ITGA8)
   04514 Cell adhesion molecules
    101134255 (ITGA8)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101134255 (ITGA8)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101134255 (ITGA8)
   04810 Regulation of actin cytoskeleton
    101134255 (ITGA8)
09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101134255 (ITGA8)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101134255 (ITGA8)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101134255 (ITGA8)
   05414 Dilated cardiomyopathy
    101134255 (ITGA8)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:ggo04515]
    101134255 (ITGA8)
Cell adhesion molecules [BR:ggo04515]
Integrins
  Integrin alpha subunits
   101134255 (ITGA8)

SSDB

Motif

Pfam:

Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

8:complement(join(24497654..24497740,24499792..24499914,24511516..24511617,24535460..24535573,24545068..24545196,24559224..24559382,24562531..24562636,24573631..24573711,24579264..24579343,24584255..24584347,24591268..24591415,24592785..24592852,24593346..24593483,24594738..24594892,24595295..24595350,24600714..24600821,24603568..24603613,24631088..24631279,24633846..24634051,24642042..24642094,24645688..24645744,24647568..24647611,24658347..24658391,24659368..24659493,24664312..24664357,24665446..24665507,24670713..24670836,24674646..24674746,24705255..24705388,24706056..24706264))

AA seq 1063 aa
MSPGASRGPRGSQAPLIAPLCCAAAALGMMLWTPACQAFNLDVEKLTVYSGPKGSYFGYA
VDFHVPDASTASVLVGAPKANTSQPDIMEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR
VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA
YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY
SFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSI
INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQI
YLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDVAIGVPFAGKDQRGKVL
IYNGNKDGLNTKPSQVLQGVWASHAIPSGFGFTLRGDSDIDRNDYPDLIVGAFGTGKVAV
YRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMA
EVQLDSLKQKGAIKRTLFLDNHQAHRIFPLVIKRQKSHQCQNFIVYLRDETEFRDKLSPI
NISLNYSLDESTFKEGLGVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKH
QVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV
TRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQIN
ITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTIL
EVGWPFSARDEFLLYIFHIQTLGPLQCQTNPNINPQDIKPAASPEDTPELSAFLQNSTIP
HLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGQLEGGESAVLKVRSRLWAHTFLQ
RKNDPYALASLVSFEVKKMPYKDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAIL
LGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA

NT seq 3192 nt +upstreamnt +downstreamnt
atgtcgcccggagccagccgcggtccccggggaagccaggcgccgctgatcgcgcccctc
tgctgcgccgcggccgcgctggggatgatgctgtggacccccgcctgtcaggcgttcaac
ctggacgtggaaaagctcacagtgtacagcggccccaagggcagctacttcggctacgcc
gtggacttccacgtacccgacgccagcacagcgagtgtcttggtgggggcgcccaaagcc
aacaccagccagcccgatatcatggaagggggagccgtctattactgtccttggcccgcg
gaggggtctgcgcagtgcaggcagataccgtttgacaccaccaacaacagaaagatcaga
gttaatggaaccaaagaacctatcgagttcaaatccaatcagtggttcggagcaacagtg
aaagctcacaaaggaaaagttgtggcctgtgctcctttatatcactggagaactcttaaa
ccgacaccagaaaaggacccagttggcacctgctatgtagcaattcagaacttcagcgcc
tatgccgagttctctccttgccggaacagcaatgctgatccggaaggccagggttactgc
caagcaggatttagtctggatttttataagaatggagaccttattgtgggaggacctggg
agtttctactggcaagggcaagtgatcactgccagtgttgcagatatcattgcaaattac
tcattcaaggatatcctcaggaaactggcaggagaaaagcaaacggaagtggctccagct
tcctatgatgacagttaccttggatactcagttgctgctggggagtttactggggattct
cagcaagaattggttgctggaattccaagaggagcacagaattttggatatgtttccatc
attaactctacggatatgacgtttattcagaatttcacgggagaacagatggcatcttat
tttggatataccgttgtcgtatcagatgttaacagtgatggactggatgatgtcctggtt
ggggcacctctctttatggaacgtgaatttgagagcaaccccagagaagtagggcaaatc
tacctgtatttgcaagtgagctctctcctcttcagagacccccagatcctcactggcacc
gagacgtttgggagattcggtagtgctatggcacacttaggagacctgaaccaagatgga
tacaatgacgttgccatcggagtgccttttgcaggcaaggatcaaagaggcaaagtgctc
atttataatgggaacaaagatggcttaaacaccaagccttcccaagttctgcaaggagtg
tgggcctcacacgctatcccttccggatttggctttactttaagaggagattcagacata
gacaggaatgattacccagatttgattgtgggtgcatttggaacaggaaaagttgctgtt
tacagagcaagaccggttgtgactgtagatgcccagcttctgctgcacccaatgattatc
aatcttgaaaataaaacttgccaggttccagactctatgacatctgctgcctgcttttct
ttaagagtatgtgcatctgtcacaggccagagcattgcaaacacaatagtcttgatggca
gaggtgcaattagattccctgaaacagaaaggagctattaaacggacgctcttccttgat
aaccatcaggctcaccgcatcttccctcttgtgataaaacggcagaaatcccaccagtgc
cagaatttcatcgtttaccttcgagatgaaactgaattccgagataaattatctccaatc
aacattagtttgaattacagtttggatgaatccacctttaaagaaggcctgggagtgaaa
ccaatattgaactactacagagaaaacattgttagtgaacaggctcacattctagtggac
tgtggagaagacaatctgtgtgttcctgacttgaagctgtcggctagaccagataagcat
caggtaatcattggagatgaaaatcaccttatgctcataataaatgcaagaaatgaagga
gaaggagcatatgaagctgaactctttgtaatgataccagaagaggcagattatgttggg
atcgaacgcaacaacaagggatttcgaccactgagctgtgagtacaagatggaaaacgta
accaggatggtggtgtgtgaccttgggaaccctatggtgtctggaacaaattattccctg
ggcctccgatttgcagttccacgtcttgagaaaacaaacatgagcattaacttcgatctc
caaatcagaagttccaacaaggacaatccagacagcaattttgtgagcctgcaaatcaac
atcactgctgtagcgcaggtggaaataagaggagtgtcacaccctccgcagattgttctg
cccattcataactgggaaccagaagaggagccccacaaagaggaggaggttggaccattg
gtggaacatatttatgagctgcacaatattggaccaagtaccatcagtgacaccatcctg
gaggtgggctggcctttctctgcccgggatgaatttcttctctatattttccatattcaa
actctgggacctctgcagtgccaaacaaatcctaatatcaatccacaggatataaagcct
gctgcctccccagaggacacccctgagctcagcgcctttttgcaaaactctactattcct
catcttgtcaggaagagggatgtgcatgtggtcgaattccacagacagagccctgcaaaa
atactgaactgcacaaatatcgagtgtttacaaatctcctgtgcagtgggacaactcgaa
ggaggagaaagcgcagtcctgaaagtcaggtcacgattgtgggcccacaccttcctccag
agaaaaaatgatccctatgctcttgcatccctggtgtcctttgaagttaagaagatgcct
tataaagatcagccagcaaaactcccagaaggaagcatagcaattaagacatcagttatt
tgggcaactccgaatgtttccttctcaatcccattatgggtaataatactagcaatactt
cttggattgttggttctcgccattttaaccttagctttatggaagtgtggattctttgac
agagccagacctcctcaggaggacatgaccgacagggaacagctgacaaatgacaagacc
cctgaggcatga

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