KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101134525
Entry
101134525         CDS       T02442                                 
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01521  EGFR tyrosine kinase inhibitor resistance
ggo01522  Endocrine resistance
ggo04012  ErbB signaling pathway
ggo04066  HIF-1 signaling pathway
ggo04140  Autophagy - animal
ggo04150  mTOR signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04152  AMPK signaling pathway
ggo04211  Longevity regulating pathway
ggo04213  Longevity regulating pathway - multiple species
ggo04350  TGF-beta signaling pathway
ggo04371  Apelin signaling pathway
ggo04666  Fc gamma R-mediated phagocytosis
ggo04714  Thermogenesis
ggo04910  Insulin signaling pathway
ggo04931  Insulin resistance
ggo05163  Human cytomegalovirus infection
ggo05165  Human papillomavirus infection
ggo05170  Human immunodeficiency virus 1 infection
ggo05200  Pathways in cancer
ggo05205  Proteoglycans in cancer
ggo05207  Chemical carcinogenesis - receptor activation
ggo05210  Colorectal cancer
ggo05212  Pancreatic cancer
ggo05221  Acute myeloid leukemia
ggo05224  Breast cancer
ggo05225  Hepatocellular carcinoma
ggo05226  Gastric cancer
ggo05231  Choline metabolism in cancer
ggo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101134525 (RPS6KB2)
   04350 TGF-beta signaling pathway
    101134525 (RPS6KB2)
   04371 Apelin signaling pathway
    101134525 (RPS6KB2)
   04066 HIF-1 signaling pathway
    101134525 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    101134525 (RPS6KB2)
   04152 AMPK signaling pathway
    101134525 (RPS6KB2)
   04150 mTOR signaling pathway
    101134525 (RPS6KB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101134525 (RPS6KB2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    101134525 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101134525 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    101134525 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    101134525 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    101134525 (RPS6KB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101134525 (RPS6KB2)
   05205 Proteoglycans in cancer
    101134525 (RPS6KB2)
   05207 Chemical carcinogenesis - receptor activation
    101134525 (RPS6KB2)
   05231 Choline metabolism in cancer
    101134525 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101134525 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101134525 (RPS6KB2)
   05212 Pancreatic cancer
    101134525 (RPS6KB2)
   05225 Hepatocellular carcinoma
    101134525 (RPS6KB2)
   05226 Gastric cancer
    101134525 (RPS6KB2)
   05221 Acute myeloid leukemia
    101134525 (RPS6KB2)
   05224 Breast cancer
    101134525 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101134525 (RPS6KB2)
   05163 Human cytomegalovirus infection
    101134525 (RPS6KB2)
   05165 Human papillomavirus infection
    101134525 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101134525 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101134525 (RPS6KB2)
   01522 Endocrine resistance
    101134525 (RPS6KB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ggo01001]
    101134525 (RPS6KB2)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101134525 (RPS6KB2)
Protein kinases [BR:ggo01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   101134525 (RPS6KB2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 101134525
NCBI-ProteinID: XP_004051682
Ensembl: ENSGGOG00000009999
UniProt: G3R3D8
LinkDB
Position
9:join(75356810..75356887,75357246..75357286,75357384..75357504,75357791..75357859,75359619..75359766,75360852..75360909,75360989..75361089,75361204..75361294,75361378..75361468,75361592..75361699,75362247..75362309,75362451..75362528,75362630..75362737,75362835..75362947,75363242..75363422)
AA seq 482 aa
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNLGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRA
PISPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPLGTKKSKRGRGRP
GR
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcggccgtgtttgatttggatttggagacggaggaaggcagcgagggcgagggcgag
ccagaactcagccccgcggacgcgtgtccccttgccgagttgagggcagctggtctagag
cctgtgggacactatgaagaggtggagctgactgagaccagcgtgaaccttggcccagag
cgcatcgggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaag
gtgttccaggtgcgaaaggtgcaaggcaccaacttgggcaaaatatatgccatgaaagtc
ctaaggaaggccaaaattgtgcgcaacgccaaggacacagcacacacacgggctgagcgg
aacattctagagtcagtgaagcacccctttattgtggaactggcctatgccttccagact
ggtggcaaactctatctcatccttgagtgcctcagtggtggcgagctcttcacgcatctg
gagcgagagggcatcttcctggaagatacggcctgcttctacctggctgagatcacgctg
gccctgggccatctccactcccagggcatcatctaccgggacctcaagcctgagaacatc
atgctcagcagccagggccacatcaaactgaccgactttggactctgcaaggagtcgatc
catgagggcgccgtcactcacaccttctgcggcaccattgagtacatggcccctgagatt
ctggtgcgcagtggccacaaccgggctgtggactggtggagcctgggggccctgatgtac
gacatgctcactggatcgccgcccttcaccgcagagaaccggaagaaaaccatggataag
atcatcaagggcaagctggcgctgcccccctacctcaccccagatgcccgggaccttgtc
aaaaagtttctgaaacggaatcccagccagcggattgggggtggcccaggggatgctgct
gatgtgcagagacatccctttttccggcacatgaattgggacgaccttctcgcctggcgt
gtggacccccctttcaggccctgtctgcagtcagaggaggacgtgagccagtttgatacc
cgcttcacacggcagacgccggtggacagtcctgatgacacagccctcagcgagagtgcc
aaccaggccttcctgggcttcacatacgtggcgccgtctgtcctggacagcatcaaggag
ggcttctccttccagcccaagctgcgctcacccaggcgcctcaacagtagcccccgggcc
cccatcagccccctcaagttctccccttttgaggggtttcggcccagccccagcctgccg
gagcccacggagctacctctacctccactcctgccaccgccgccgccctcgaccaccgcc
cctctccccatccgtccccccttagggaccaagaagtccaagaggggccgtgggcgtcca
gggcgctag

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