KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101135430
Entry
101135430         CDS       T02442                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 isoform X3
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04015  Rap1 signaling pathway
ggo04024  cAMP signaling pathway
ggo04062  Chemokine signaling pathway
ggo04071  Sphingolipid signaling pathway
ggo04145  Phagosome
ggo04148  Efferocytosis
ggo04151  PI3K-Akt signaling pathway
ggo04310  Wnt signaling pathway
ggo04360  Axon guidance
ggo04370  VEGF signaling pathway
ggo04380  Osteoclast differentiation
ggo04510  Focal adhesion
ggo04520  Adherens junction
ggo04530  Tight junction
ggo04613  Neutrophil extracellular trap formation
ggo04620  Toll-like receptor signaling pathway
ggo04650  Natural killer cell mediated cytotoxicity
ggo04662  B cell receptor signaling pathway
ggo04664  Fc epsilon RI signaling pathway
ggo04666  Fc gamma R-mediated phagocytosis
ggo04670  Leukocyte transendothelial migration
ggo04722  Neurotrophin signaling pathway
ggo04810  Regulation of actin cytoskeleton
ggo04932  Non-alcoholic fatty liver disease
ggo04933  AGE-RAGE signaling pathway in diabetic complications
ggo04972  Pancreatic secretion
ggo05014  Amyotrophic lateral sclerosis
ggo05020  Prion disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05100  Bacterial invasion of epithelial cells
ggo05132  Salmonella infection
ggo05135  Yersinia infection
ggo05163  Human cytomegalovirus infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05169  Epstein-Barr virus infection
ggo05170  Human immunodeficiency virus 1 infection
ggo05200  Pathways in cancer
ggo05203  Viral carcinogenesis
ggo05205  Proteoglycans in cancer
ggo05208  Chemical carcinogenesis - reactive oxygen species
ggo05210  Colorectal cancer
ggo05211  Renal cell carcinoma
ggo05212  Pancreatic cancer
ggo05231  Choline metabolism in cancer
ggo05415  Diabetic cardiomyopathy
ggo05416  Viral myocarditis
ggo05417  Lipid and atherosclerosis
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101135430 (RAC1)
   04014 Ras signaling pathway
    101135430 (RAC1)
   04015 Rap1 signaling pathway
    101135430 (RAC1)
   04310 Wnt signaling pathway
    101135430 (RAC1)
   04370 VEGF signaling pathway
    101135430 (RAC1)
   04071 Sphingolipid signaling pathway
    101135430 (RAC1)
   04024 cAMP signaling pathway
    101135430 (RAC1)
   04151 PI3K-Akt signaling pathway
    101135430 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    101135430 (RAC1)
   04148 Efferocytosis
    101135430 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101135430 (RAC1)
   04520 Adherens junction
    101135430 (RAC1)
   04530 Tight junction
    101135430 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101135430 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101135430 (RAC1)
   04620 Toll-like receptor signaling pathway
    101135430 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    101135430 (RAC1)
   04662 B cell receptor signaling pathway
    101135430 (RAC1)
   04664 Fc epsilon RI signaling pathway
    101135430 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    101135430 (RAC1)
   04670 Leukocyte transendothelial migration
    101135430 (RAC1)
   04062 Chemokine signaling pathway
    101135430 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    101135430 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101135430 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    101135430 (RAC1)
   04380 Osteoclast differentiation
    101135430 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101135430 (RAC1)
   05205 Proteoglycans in cancer
    101135430 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101135430 (RAC1)
   05203 Viral carcinogenesis
    101135430 (RAC1)
   05231 Choline metabolism in cancer
    101135430 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101135430 (RAC1)
   05212 Pancreatic cancer
    101135430 (RAC1)
   05211 Renal cell carcinoma
    101135430 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101135430 (RAC1)
   05163 Human cytomegalovirus infection
    101135430 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101135430 (RAC1)
   05169 Epstein-Barr virus infection
    101135430 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101135430 (RAC1)
   05135 Yersinia infection
    101135430 (RAC1)
   05100 Bacterial invasion of epithelial cells
    101135430 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101135430 (RAC1)
   05020 Prion disease
    101135430 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    101135430 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101135430 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    101135430 (RAC1)
   05415 Diabetic cardiomyopathy
    101135430 (RAC1)
   05416 Viral myocarditis
    101135430 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    101135430 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101135430 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ggo04131]
    101135430 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ggo04147]
    101135430 (RAC1)
   04031 GTP-binding proteins [BR:ggo04031]
    101135430 (RAC1)
Membrane trafficking [BR:ggo04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    101135430 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    101135430 (RAC1)
  Macropinocytosis
   Ras GTPases
    101135430 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    101135430 (RAC1)
Exosome [BR:ggo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101135430 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   101135430 (RAC1)
  Exosomal proteins of colorectal cancer cells
   101135430 (RAC1)
  Exosomal proteins of bladder cancer cells
   101135430 (RAC1)
GTP-binding proteins [BR:ggo04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    101135430 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 101135430
NCBI-ProteinID: XP_004045124
Ensembl: ENSGGOG00000026733
UniProt: G3SDK5
LinkDB
Position
6:complement(join(13764303..13764433,13764722..13764881,13766564..13766626,13774732..13774849,13779513..13779584,13792295..13792329))
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggcgctgtaggtaaaacttgcctactg
ataagttacacaaccaatgcatttcctggagaatatatccctactgtctttgacaattat
tctgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacagctgga
caagaagattatgacagattacgccccctatcctatccgcaaacagatgtgttcttaatt
tgcttttcccttgtgagtcctgcatcatttgaaaatgtccgtgcaaagtggtatcctgag
gtgcggcaccactgtcccaacactcccatcatcctagtgggaactaaacttgatcttagg
gatgataaagacacgatcgagaaactgaaggagaagaagctgactcccatcacctatccg
cagggtctagccatggctaaggagattggtgctgtaaaatacctggagtgctcggcgctc
acacagcgaggcctcaagacagtgtttgacgaagcgatccgagcagtcctctgcccacct
cccgtgaagaagaggaagagaaaatgcctgctgttgtaa

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