KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101136113
Entry
101136113         CDS       T02442                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb
  KO
K06476  integrin alpha 2B
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04015  Rap1 signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04510  Focal adhesion
ggo04512  ECM-receptor interaction
ggo04518  Integrin signaling
ggo04611  Platelet activation
ggo04613  Neutrophil extracellular trap formation
ggo04640  Hematopoietic cell lineage
ggo04810  Regulation of actin cytoskeleton
ggo04820  Cytoskeleton in muscle cells
ggo05165  Human papillomavirus infection
ggo05200  Pathways in cancer
ggo05222  Small cell lung cancer
ggo05410  Hypertrophic cardiomyopathy
ggo05412  Arrhythmogenic right ventricular cardiomyopathy
ggo05414  Dilated cardiomyopathy
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101136113 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    101136113 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    101136113 (ITGA2B)
   04518 Integrin signaling
    101136113 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101136113 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101136113 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    101136113 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    101136113 (ITGA2B)
   04611 Platelet activation
    101136113 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    101136113 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101136113 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    101136113 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101136113 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101136113 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    101136113 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101136113 (ITGA2B)
   05414 Dilated cardiomyopathy
    101136113 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ggo01009]
    101136113 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ggo04147]
    101136113 (ITGA2B)
   04515 Cell adhesion molecules [BR:ggo04515]
    101136113 (ITGA2B)
   04090 CD molecules [BR:ggo04090]
    101136113 (ITGA2B)
Protein phosphatases and associated proteins [BR:ggo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101136113 (ITGA2B)
Exosome [BR:ggo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101136113 (ITGA2B)
Cell adhesion molecules [BR:ggo04515]
 Integrins
  Integrin alpha subunits
   101136113 (ITGA2B)
CD molecules [BR:ggo04090]
 Proteins
  101136113 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 101136113
NCBI-ProteinID: XP_018882226
Ensembl: ENSGGOG00000012852
UniProt: G3RAS1
LinkDB
Position
4:join(47875120..47875514,47878654..47878775,47878864..47878961,47879069..47879234,47879450..47879499,47879576..47879621,47879714..47879842,47880241..47880288,47880472..47880515,47880686..47880739,47880878..47880930,47881120..47881331,47883760..47883942,47884176..47884221,47884330..47884434,47884519..47884574,47884667..47884818,47885006..47885131,47886115..47886182,47886316..47886463,47887038..47887130,47887743..47887822,47888439..47888519,47888643..47888742,47888842..47888994,47889112..47889237,47889717..47889830,47890068..47890169,47890358..47890474,47892400..47892459)
AA seq 1108 aa
MNIHPRGGLTHFLAILATMSPEAIALCSARCSASYLGFQFDKKRLPVEESEGKEEELAHS
CLGGCGRRKMARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSHFG
FSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLLDLRDETRNVG
SQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRR
AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPI
ADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTW
SWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADR
KLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDVAVAAPY
GGPSGRGQVLVFLGQSEGLSSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAY
GANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQ
KLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRD
KLSPIVLSLNVSLPPTEAGLAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTG
SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMQALSNVEGFERLICNQKKEN
ETRVVLCELGNPMKKNAQTGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDV
PVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLS
IHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPTPSPSPIHPAHHKRDRRQ
IFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD
QFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVRTQLLRALEERAIPIWWVLVGVLGGLLLL
TILVLAMWKVGFFKRNRPPLEDDDEEGE
NT seq 3327 nt   +upstreamnt  +downstreamnt
atgaacatccaccctcggggtggcctcacccacttcctggcaattctagccaccatgagt
ccagaggctatagccctttgctctgcccgttgctcagcaagttacttggggttccagttt
gataaaaaaagacttcctgtggaggaatctgaagggaaggaggaggagctggcccattcc
tgcctgggaggttgtggaagaaggaagatggccagagctttgtgtccactgcaagccctc
tggcttctggagtgggtgctgctgctcttgggaccttgtgctgcccctccagcctgggcc
ttgaacctggacccagtgcagctcaccttctatgcaggccccaatggcagccactttgga
ttttcactggacttccacaaggacagccatgggagagtggccatcgtggtgggcgccccg
cggaccctgggccccagccaggaggagacgggcggcgtgttcctgtgcccctggagggcc
gagggcggccagtgcccctcgctgctcttggacctccgtgatgagacccgaaatgtaggc
tcccaaactttacaaaccttcaaggcccgccaaggactgggggcgtcggtcgtcagctgg
agcgacgtcattgtggcctgcgccccctggcagcactggaacgtcctagaaaagactgag
gaggctgagaagacgcccgtaggtagctgctttttggctcagccagagagcggccgccgc
gccgagtactccccctgtcgcgggaacaccctgagccgcatttacgtggaaaatgatttt
agctgggacaagcgttactgtgaagcgggcttcagctccgtggtcactcaggccggagag
ctggtgcttggggctcctggcggctattatttcttgggtctcctggcccaggctccaatt
gcggatattttctcgagttaccgcccaggcatccttttgtggcacgtgtcctcccagagc
ctctcctttgactccagcaacccagagtacttcgacggctactgggggtactcggtggcc
gtgggcgagttcgacggggatctcaacactacagagtacgtcgtcggtgcccccacttgg
agctggaccctgggagcggtggaaattttggactcctactaccagaggctgcatcggctg
cgcggagagcagatggcgtcgtattttgggcattcggtggctgtcactgacgtcaacggg
gatgggaggcatgatctgctggtgggcgctccactgtatatggagagccgggcagaccga
aaactggccgaagtggggcgtgtgtatttgttcctgcagccgcgaggcccccacgcgctg
ggtgcccccagcctcctgctgactggcacacagctctatgggcgattcggctctgccatc
gcacccctgggcgacctcgaccgggatggctacaatgacgttgcagtggctgccccctac
gggggtcccagtggccggggccaagtgctggtgttcctgggtcagagtgaggggctgagc
tcacgtccctcccaggtcctggacagccccttccccacaggctctgcctttggcttctcc
cttcgaggtgccgtagacatcgatgacaacggatacccagacctgatcgtgggagcttac
ggggccaaccaggtggctgtgtacagagctcagccagtggtgaaggcctctgtccagcta
ctggtgcaagattcactgaatcctgctgtgaagagctgtgtcctaccccagaccaagaca
cccgtgagctgcttcaacatccagatgtgtgttggagccactgggcacaacattcctcag
aagctatccctaaatgccgagctgcagctggaccggcagaagccccgccagggccggcgg
gtgctgctgctgggctctcaacaggcaggcactaccctgaacctggatctgggtggaaag
cacagccccatctgccataccaccatggccttccttcgagatgaggcagacttccgggac
aagctgagccccattgtgctcagcctcaatgtgtccctaccgcccacggaggctggactg
gcccctgctgtcgtgctgcatggagacacccatgtgcaggagcagacacgaatcgtcctg
gactgtggggaagatgacgtatgtgtgccccagcttcagctcactgccagcgtgacgggc
tccccgctcctagttggggcagataatgtcctggagctgcagatggacgcagccaacgag
ggcgagggggcctatgaagcagagctggccgtgcacctgccccagggtgcccactacatg
caagccctaagcaacgtcgagggctttgagagactcatctgtaatcagaagaaggagaat
gagaccagggtggtgctgtgtgagctgggcaaccccatgaaaaagaacgcccagacagga
atcgcgatgttggtgagcgtggggaatctggaagaggctggggagtctgtgtccttccag
ctgcagatacggagcaagaacagccagaatccaaacagcaagattgtgctgctggacgtg
ccggtccgggcagaggcccaagtggagctgcgagggaactcctttccagcctccctggtg
gtggcggcagaagaaggtgagagggagcagaacagcttggacagctggggacccaaagtg
gagcacacctatgagctccacaacaatggccctgggactgtgaatggccttcacctcagc
atccacctcccgggacagtcccagccctccgacctgctctacatcctggatatacagccc
caggggggccttcagtgcttcccacagcctcctgtcaaccctctcaaggtggactggggg
ctgcccacccccagcccctcccccattcacccggcccatcacaagcgggatcgcagacag
atcttcctgccagagcccgagcagccctcgaggcttcaggatccagttctcgtaagctgc
gactcggcgccctgtactgtggtgcagtgtgacctgcaggagatggcgcgcgggcagcgg
gccatggtcacggtgctggccttcctgtggctgcccagcctctaccagaggcctctggat
cagtttgtgctgcagtcgcacgcatggttcaacgtgtcctccctcccctatgcggtgccc
ccgctcagcctgccccgaggggaagctcaggtgcggacacagctgctccgggccttggag
gagagggccattccaatctggtgggtgctggtgggtgtgctgggtggcctgctgctgctc
accatcctggtcctggccatgtggaaggtcggcttcttcaagcggaaccggccacccctg
gaagatgatgatgaagagggggagtga

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