KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101142773
Entry
101142773         CDS       T02442                                 
Symbol
ITGB2
Name
(RefSeq) integrin beta-2
  KO
K06464  integrin beta 2
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04015  Rap1 signaling pathway
ggo04145  Phagosome
ggo04390  Hippo signaling pathway
ggo04514  Cell adhesion molecule (CAM) interaction
ggo04517  IgSF CAM signaling
ggo04610  Complement and coagulation cascades
ggo04613  Neutrophil extracellular trap formation
ggo04650  Natural killer cell mediated cytotoxicity
ggo04670  Leukocyte transendothelial migration
ggo04810  Regulation of actin cytoskeleton
ggo05133  Pertussis
ggo05134  Legionellosis
ggo05140  Leishmaniasis
ggo05144  Malaria
ggo05146  Amoebiasis
ggo05150  Staphylococcus aureus infection
ggo05152  Tuberculosis
ggo05166  Human T-cell leukemia virus 1 infection
ggo05323  Rheumatoid arthritis
ggo05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101142773 (ITGB2)
   04390 Hippo signaling pathway
    101142773 (ITGB2)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    101142773 (ITGB2)
   04517 IgSF CAM signaling
    101142773 (ITGB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    101142773 (ITGB2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101142773 (ITGB2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    101142773 (ITGB2)
   04613 Neutrophil extracellular trap formation
    101142773 (ITGB2)
   04650 Natural killer cell mediated cytotoxicity
    101142773 (ITGB2)
   04670 Leukocyte transendothelial migration
    101142773 (ITGB2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101142773 (ITGB2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    101142773 (ITGB2)
   05134 Legionellosis
    101142773 (ITGB2)
   05150 Staphylococcus aureus infection
    101142773 (ITGB2)
   05152 Tuberculosis
    101142773 (ITGB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101142773 (ITGB2)
   05144 Malaria
    101142773 (ITGB2)
   05140 Leishmaniasis
    101142773 (ITGB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    101142773 (ITGB2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    101142773 (ITGB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ggo04131]
    101142773 (ITGB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ggo04147]
    101142773 (ITGB2)
   04515 Cell adhesion molecules [BR:ggo04515]
    101142773 (ITGB2)
   04090 CD molecules [BR:ggo04090]
    101142773 (ITGB2)
Membrane trafficking [BR:ggo04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    101142773 (ITGB2)
Exosome [BR:ggo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101142773 (ITGB2)
Cell adhesion molecules [BR:ggo04515]
 Integrins
  Integrin beta subunits
   101142773 (ITGB2)
CD molecules [BR:ggo04090]
 Proteins
  101142773 (ITGB2)
SSDB
Motif
Pfam: Integrin_beta EGF_integrin Integrin_B_tail Integrin_b_cyt PSI_integrin I-EGF_1 EGF_2 vWA_SIBA-E
Other DBs
NCBI-GeneID: 101142773
NCBI-ProteinID: XP_063558759
Ensembl: ENSGGOG00000014457
UniProt: G3REV7
LinkDB
Position
22:complement(join(46735361..46735423,46735727..46735893,46737878..46738080,46738461..46738680,46739163..46739407,46740998..46741185,46742588..46742728,46744142..46744231,46748262..46748357,46749518..46749673,46750690..46750931,46752600..46752770,46756125..46756305,46759411..46759499,46759852..46759909))
AA seq 769 aa
MLGLRPPLLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSI
RCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFR
RAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFV
NTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAM
MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFD
YPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAY
NKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATEC
IQEQSFVIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKN
CECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLCHTSDVPGKEIYGQYCECDTIN
CERYNGQVCGGPGRGLCFCGKCHCRPGFDGSACQCERTTEGCLNPRRVECSGRGRCRCNV
CECHSGYQLPLCQECPGCPSPCGKYISCAECLKFEKGPFGKNCSVACPGLQLSNNPVKGR
TCKERDSEGCWVAYTLQQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLL
VIWKALIHLSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
NT seq 2310 nt   +upstreamnt  +downstreamnt
atgctgggcctgcgccccccactgctcgccctggtggggctgctctccctcgggtgcgtc
ctctctcaggagtgcacgaagttcaaggtcagcagctgccgggaatgcatcgagtcgggg
cccggctgcacctggtgccagaagctgaacttcacagggccgggggatcctgactccatt
cgctgcgacacccggccacagctgctcatgaggggctgtgcagctgacgacatcatggac
cccacaagcctcgctgaaacccaggaagaccacaatgggggccagaagcagctgtcccca
caaaaagtgacgctttacctgcgaccaggccaggcagcagcgttcaacgtgaccttccgg
cgggccaagggctaccccatcgacctgtactacctgatggacctctcctactccatgctt
gatgacctcaggaatgtcaagaagctgggtggcgacctgctccgggccctcaacgagatc
accgagtccggccgcattggcttcgggtccttcgtggacaagaccgtgctgccgttcgtg
aacacgcaccccgataagctgcgaaacccatgccccaacaaggagaaagagtgccagccc
ccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccagtttcagaccgag
gttgggaagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatg
atgcaggtcgccgcctgcccggaggaaatcggctggcgcaacgtcacgcggctgctggtg
tttgccactgatgacggcttccatttcgcgggcgacgggaagctgggcgccatcctgacc
cccaacgacggccgctgtcacctggaggacaacttgtacaagaggagcaacgaattcgac
tacccatcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttc
gcggtgaccagtaggatggtgaagacctacgagaaactcaccgagatcatccccaagtca
gccgtgggggagctgtctgaggactccagcaatgtggtccatctcattaagaatgcttac
aataaactctcctccagggtcttcctggatcacaacgccctccccgacaccctgaaagtc
acctatgactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgt
gatggcgtgcagatcaatgtcccgatcaccttccaggtgaaggtcacggccacagagtgc
atccaggagcagtcgtttgtcatccgggcgctgggcttcacggacatagtgaccgtgcag
gtccttccccagtgcgagtgccggtgccgggaccagagcagagaccgcagcctctgccat
ggcaagggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaac
tgtgagtgccagacacagggccggagcagccaggagctggaaggaagctgccggaaggac
aacaactccatcatctgctcagggctgggggactgtgtctgcgggcagtgcctgtgccac
accagtgacgtccccggcaaggagatatacgggcagtactgcgagtgtgacaccatcaac
tgtgagcgctacaacggccaggtctgcggtggcccggggagggggctctgcttctgcggg
aagtgccactgccgcccgggctttgacggttcagcgtgccagtgcgagaggaccaccgag
ggctgcctgaacccgcggcgtgttgagtgcagtggccgtggccggtgccgctgcaacgta
tgtgagtgccattcaggctaccagctgcctctgtgccaggagtgccccggctgcccctca
ccctgtggcaagtacatctcctgtgccgagtgcctgaagttcgaaaagggcccctttggg
aagaactgcagcgtggcgtgtccgggcctgcagctgtcgaacaaccccgtgaagggcagg
acctgcaaggagagggactcagagggctgctgggtggcctacacgctgcagcagcaggac
gggatggaccgctacctcatctatgtggatgagagccgagagtgcgtggcaggccccaac
atcgccgccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcatcctcctgctg
gtcatctggaaggctctgatccacctgagcgacctccgggagtacaggcgctttgagaag
gagaagctcaagtcccagtggaacaatgataatccccttttcaagagcgccaccacgacg
gtcatgaaccctaagtttgctgagagttag

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