KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101143561
Entry
101143561         CDS       T02442                                 
Symbol
MECOM
Name
(RefSeq) histone-lysine N-methyltransferase MECOM isoform X6
  KO
K04462  [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00310  Lysine degradation
ggo01100  Metabolic pathways
ggo04010  MAPK signaling pathway
ggo05200  Pathways in cancer
ggo05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    101143561 (MECOM)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101143561 (MECOM)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101143561 (MECOM)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101143561 (MECOM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ggo03000]
    101143561 (MECOM)
   03036 Chromosome and associated proteins [BR:ggo03036]
    101143561 (MECOM)
Enzymes [BR:ggo01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.367  [histone H3]-lysine9 N-methyltransferase
     101143561 (MECOM)
Transcription factors [BR:ggo03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 PRDM
    101143561 (MECOM)
Chromosome and associated proteins [BR:ggo03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     101143561 (MECOM)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 zf-C2H2_6 zf-C2H2_jaz C2CH-3rd_BIRD-IDD zf-H2C2_5 Zap1_zf1 zf-BED zf-C2H2_8 zf-met Zn_ribbon_8 DUF7128 C2CH-4th_BIRD-IDD zf-C2H2_11 HVO_0758 CEP104_ZnF
Other DBs
NCBI-GeneID: 101143561
NCBI-ProteinID: XP_004038022
Ensembl: ENSGGOG00000013086
UniProt: G3SG88
LinkDB
Position
2:complement(join(180177345..180177479,180181435..180181618,180182434..180182670,180185390..180185534,180187508..180187677,180193290..180193367,180194465..180194631,180200329..180200355,180205181..180205268,180208010..180209366,180213671..180213824,180215195..180215342,180220480..180220696,180224068..180224116))
AA seq 1051 aa
MKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQ
KLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIR
HQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKH
IHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCE
GKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFS
FSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKH
PSVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESD
KEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASI
AEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPG
EVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL
TEPRKNHVFGEKKGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYL
RPSPGFLFHPQFQLPDQRTWMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNA
LPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHV
RNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKE
DAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLD
EEDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALD
HIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKES
LHSTSHSSSNVWHSMARAAAESSAIQSISHV
NT seq 3156 nt   +upstreamnt  +downstreamnt
atgaagagcgaagactatccccatgaaactatggcgccggatatccacgaagaacggcaa
tatcgctgtgaagactgtgaccagctctttgaatctaaggctgaactagcagatcaccaa
aagtttccatgcagtactcctcactcagcattttcaatggttgaagaggactttcagcaa
aaactcgaaagcgagaatgatctccaagagatacacacgatccaggagtgtaaggaatgt
gaccaagtttttcctgatttgcaaagcctggagaaacacatgctgtcacatactgaagag
agggaatacaagtgtgatcagtgtcccaaggcatttaactggaagtccaatttaattcgc
caccagatgtcacatgacagtggaaagcactatgaatgtgaaaactgtgccaaggttttc
acggaccctagcaaccttcagcggcacattcgctctcagcatgtcggtgcccgggcccat
gcatgcccggagtgtggcaaaacgtttgccacttcgtcgggcctcaaacaacacaagcac
atccacagcagtgtgaagccctttatctgtgaggtctgccataaatcctatactcagttt
tcaaacctttgccgtcataagcgcatgcatgctgattgcagaacccaaatcaagtgcaaa
gactgtggacaaatgttcagcactacgtcttccttaaataaacacaggaggttttgtgag
ggcaagaaccattttgcggcaggtggattttttggccaaggcatttcacttcctggaacc
ccagctatggataaaacgtccatggttaatatgagtcatgccaacccgggccttgctgac
tattttggcgccaataggcatcctgctggtcttacctttccaacagctcctggattttct
tttagcttccctggtctgtttccttccggcttgtaccacaggcctcctttgatacctgct
agttctcctgttaaaggactatcaagtactgaacagacaaacaaaagtcaaagtcccctc
atgacacatcctcagatactgccagctacacaggatattttgaaggcactatctaaacac
ccatctgtaggggacaataagccagtggagctccagcccgagaggtcctctgaagagagg
ccccttgagaaaatcagtgaccagtcagagagtagtgaccttgatgatgtcagtacacca
agtggcagtgacctggaaacaacctcgggctctgatctggaaagtgacattgaaagtgat
aaagagaaatttaaagaaaatggtaaaatgttcaaagacaaagtaagccctcttcagaat
ctggcttcaataaataataagaaagaatacagcaatcattccattttctcaccatcttta
gaggagcagactgcggtgtcaggagctgtgaatgattctataaaggctattgcttctatt
gctgaaaaatactttggttcaacaggactggtggggctgcaagacaaaaaagttggagct
ttaccttacccttccatgtttcccctcccattttttccagcattctctcaatcaatgtac
ccatttcctgatagagacttgagatcgttacctttgaaaatggaaccccaatcaccaggt
gaagtaaagaaactgcagaagggcagctctgagtccccctttgatctcaccactaagcga
aaggacgagaagcccttgactccagtcccctccaagcctccagtgacacctgccacaagc
caagaccagcccctggatctaagtatgggcagtaggagtagagccagtgggacaaagctg
actgagcctcgaaaaaaccacgtgtttggggaaaaaaaaggaagcaacgttgaatcaaga
cctgcttcagatggttccttgcagcatgcaagacccactcctttctttatggaccctatt
tacagagtagagaaaagaaaactaactgacccacttgaagctttaaaagagaaatacttg
aggccttctccgggattcttgtttcacccacaattccaactgcctgatcagagaacttgg
atgtcagctattgaaaacatggcagaaaagctagagagcttcagtgccctgaaacctgag
gccagtgagctcttacagtcagtgccctctatgttcaacttcagggcgcctcccaatgcc
ctgccagagaaccttctgcggaagggaaaggagcgctatacctgcagatactgtggcaag
atttttccaaggtctgcaaacctaacacggcacttgagaacccacaccggagagcagcct
tacagatgcaaatactgtgacagatcatttagcatatcttctaacttgcaaaggcatgtt
cgcaacatccacaataaagagaagccatttaagtgtcacttatgtgataggtgttttggt
caacaaaccaatttagacagacacctaaagaaacatgagaatgggaacatgtccggtaca
gcaacatcatcgcctcattctgaactggaaagtacaggtgcgattctggatgacaaagaa
gatgcttacttcacagaaattcgaaatttcattgggaacagcaaccatggcagccaatct
cccaggaatgtggaggagagaatgaatggcagtcattttaaagatgaaaaggctttggtg
accagtcaaaattcagacttgctggatgatgaagaagttgaagatgaggtgttgttagat
gaggaggatgaagacaatgatattactggaaaaacaggaaaggaaccagtgacaagtaat
ttacatgaaggaaaccctgaggatgactatgaagaaaccagtgccctggagatgagttgc
aagacatccccagtgaggtataaagaggaagaatataaaagtggactttctgctctagat
catataaggcacttcacagatagcctcaaaatgaggaaaatggaagataatcaatattct
gaagctgagctgtcttcttttagtacttcccatgtgccagaggaacttaagcagccgtta
cacagaaagtccaaatcgcaggcatatgctatgatgctgtcactgtctgacaaggagtcc
ctccattctacatcccacagttcttccaatgtgtggcacagtatggccagggctgcggcg
gaatccagtgctatccagtccataagccacgtatga

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