KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101143954
Entry
101143954         CDS       T02442                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04012  ErbB signaling pathway
ggo04620  Toll-like receptor signaling pathway
ggo04664  Fc epsilon RI signaling pathway
ggo04668  TNF signaling pathway
ggo04912  GnRH signaling pathway
ggo04926  Relaxin signaling pathway
ggo04935  Growth hormone synthesis, secretion and action
ggo04936  Alcoholic liver disease
ggo05132  Salmonella infection
ggo05135  Yersinia infection
ggo05142  Chagas disease
ggo05161  Hepatitis B
ggo05166  Human T-cell leukemia virus 1 infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05169  Epstein-Barr virus infection
ggo05208  Chemical carcinogenesis - reactive oxygen species
ggo05417  Lipid and atherosclerosis
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101143954 (MAP2K4)
   04012 ErbB signaling pathway
    101143954 (MAP2K4)
   04668 TNF signaling pathway
    101143954 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101143954 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    101143954 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101143954 (MAP2K4)
   04926 Relaxin signaling pathway
    101143954 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    101143954 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101143954 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101143954 (MAP2K4)
   05161 Hepatitis B
    101143954 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101143954 (MAP2K4)
   05169 Epstein-Barr virus infection
    101143954 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101143954 (MAP2K4)
   05135 Yersinia infection
    101143954 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    101143954 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101143954 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    101143954 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101143954 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ggo01001]
    101143954 (MAP2K4)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101143954 (MAP2K4)
Protein kinases [BR:ggo01001]
 Serine/threonine kinases: STE group
  STE7 family
   101143954 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 101143954
NCBI-ProteinID: XP_018868961
Ensembl: ENSGGOG00000011958
UniProt: A0A2I2YYX3
LinkDB
Position
19:join(27312262..27312379,27346287..27346389,27373025..27373199,27387210..27387329,27399436..27399555,27402016..27402067,27404900..27405027,27416946..27417023,27420798..27420946,27431633..27431678,27432942..27433055)
AA seq 400 aa
MAAPSPSGGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARF
TLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKM
VHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME
LMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDR
SGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYE
LATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYK
ELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggcggctccgggggcggcagcggcagcggc
acccccggccccgtagggtccccggcgccaggccacccggccgtcagcagcatgcagggt
aaacgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggttt
actctgaatcccaatcctacaggagttcaaaacccacacatagagagactgagaacacac
agcattgagtcatcaggaaaactgaagatctcccctgaacaacactgggatttcactgca
gaggacttgaaagaccttggagaaattggacgaggagcttatggttctgtcaacaaaatg
gtccacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacagtggatgaa
aaagaacaaaaacaacttcttatggatttggatgtagtaatgcggagtagtgattgccca
tacattgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaa
ctcatgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgtt
attccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccactta
aaagaaaacttgaaaattattcacagagatatcaaaccttccaatattcttctggacaga
agtggaaatattaagctctgtgacttcggcatcagtggacagcttgtggactctattgcc
aagacaagagatgctggctgtaggccatacatggcacctgaaagaatagacccaagcgct
tcacgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtatgag
ttggccacaggccgatttccttatccaaaatggaatagtgtatttgatcaactaacacaa
gtcgtgaaaggagatcctccgcagctgagtaattctgaggaaagggaattctccccgagt
ttcatcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaa
gagcttctgaaacatccctttattttgatgtatgaagaacgtgccgttgaggtcgcatgc
tatgtttgtaaaatcctggatcaaatgccagctactcccagctctcccatgtatgtcgat
tga

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