KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101144930
Entry
101144930         CDS       T02442                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04020  Calcium signaling pathway
ggo04022  cGMP-PKG signaling pathway
ggo04114  Oocyte meiosis
ggo04218  Cellular senescence
ggo04310  Wnt signaling pathway
ggo04360  Axon guidance
ggo04370  VEGF signaling pathway
ggo04380  Osteoclast differentiation
ggo04625  C-type lectin receptor signaling pathway
ggo04650  Natural killer cell mediated cytotoxicity
ggo04658  Th1 and Th2 cell differentiation
ggo04659  Th17 cell differentiation
ggo04660  T cell receptor signaling pathway
ggo04662  B cell receptor signaling pathway
ggo04720  Long-term potentiation
ggo04724  Glutamatergic synapse
ggo04728  Dopaminergic synapse
ggo04921  Oxytocin signaling pathway
ggo04922  Glucagon signaling pathway
ggo04924  Renin secretion
ggo05010  Alzheimer disease
ggo05014  Amyotrophic lateral sclerosis
ggo05020  Prion disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05031  Amphetamine addiction
ggo05152  Tuberculosis
ggo05163  Human cytomegalovirus infection
ggo05166  Human T-cell leukemia virus 1 infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05170  Human immunodeficiency virus 1 infection
ggo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ggo05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101144930 (PPP3CA)
   04310 Wnt signaling pathway
    101144930 (PPP3CA)
   04370 VEGF signaling pathway
    101144930 (PPP3CA)
   04020 Calcium signaling pathway
    101144930 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    101144930 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101144930 (PPP3CA)
   04218 Cellular senescence
    101144930 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101144930 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    101144930 (PPP3CA)
   04660 T cell receptor signaling pathway
    101144930 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    101144930 (PPP3CA)
   04659 Th17 cell differentiation
    101144930 (PPP3CA)
   04662 B cell receptor signaling pathway
    101144930 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    101144930 (PPP3CA)
   04921 Oxytocin signaling pathway
    101144930 (PPP3CA)
   04924 Renin secretion
    101144930 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    101144930 (PPP3CA)
   04728 Dopaminergic synapse
    101144930 (PPP3CA)
   04720 Long-term potentiation
    101144930 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    101144930 (PPP3CA)
   04380 Osteoclast differentiation
    101144930 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101144930 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101144930 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    101144930 (PPP3CA)
   05163 Human cytomegalovirus infection
    101144930 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101144930 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101144930 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101144930 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    101144930 (PPP3CA)
   05020 Prion disease
    101144930 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    101144930 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    101144930 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101144930 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ggo01009]
    101144930 (PPP3CA)
Enzymes [BR:ggo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     101144930 (PPP3CA)
Protein phosphatases and associated proteins [BR:ggo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     101144930 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 101144930
NCBI-ProteinID: XP_004040243
Ensembl: ENSGGOG00000006762
UniProt: A0A2I2YDT1
LinkDB
Position
3:complement(join(121352818..121353014,121356119..121356148,121359199..121359296,121367351..121367435,121387981..121388055,121390125..121390250,121407443..121407537,121410098..121410175,121420551..121420690,121425157..121425302,121426401..121426512,121435662..121435786,121522954..121523154,121673084..121673141))
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcacatcttatgaaggagggaaggctggaagagagtgtt
gcattgagaataataacggagggtgcatcaattcttcgacaggaaaaaaatttgctggat
attgatgcgccagtcacagtttgtggggacattcatggacaattctttgatttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctctac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgtatggat
gcctttgactgccttcccctggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatacttcgagcc
cacgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtcccttccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaagaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccaactggcatgctccccagcggagtactttctggagga
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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