KEGG T02442: 101145372

Gorilla gorilla gorilla (western lowland gorilla): 101145372

Entry

101145372         CDS       T02442

Symbol

MSH2

Name

(RefSeq) DNA mismatch repair protein Msh2 isoform X1

K08735

DNA mismatch repair protein MSH2

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo01524

Platinum drug resistance

ggo03430

Mismatch repair

ggo05200

Pathways in cancer

ggo05210

Colorectal cancer

Brite

KEGG Orthology (KO) [BR:ggo00001]
09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    101145372 (MSH2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101145372 (MSH2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101145372 (MSH2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101145372 (MSH2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ggo03400]
    101145372 (MSH2)
DNA repair and recombination proteins [BR:ggo03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    Mismatch and loop recognition factors
     101145372 (MSH2)

SSDB

Motif

Pfam:

MutS_V MutS_III MutS_II MutS_I MutS_IV AAA_27

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

12:complement(join(92250913..92251083,92252990..92253165,92255512..92255759,92257490..92257694,92258784..92259029,92262949..92263046,92267197..92267347,92270847..92270970,92288338..92288447,92301830..92302029,92315057..92315190,92317216..92317365,92319059..92319205,92321259..92321537,92323069..92323223,92328256..92328466))

AA seq 934 aa
MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT
QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA
YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD
NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD
LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM
KLDIAAVRALNLFQGSVEDTSGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL
NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA
LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE
LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS
TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA
QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD
KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK
GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF
ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV
IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS
EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT

NT seq 2805 nt +upstreamnt +downstreamnt
atggcggtgcagccgaaggagacgctgcagttggagagcgcggccgaggtcggcttcgtg
cgcttctttcagggcatgccggagaagccgaccaccacagtgcgccttttcgaccggggc
gacttctatacggcgcacggcgaggacgcgctgctggccgcccgggaggtgttcaagacc
cagggggtgatcaagtacatggggccggcaggagcaaagaatctgcagagtgttgtgctt
agtaaaatgaattttgaatcttttgtaaaagatcttctactggttcgtcagtatagagtt
gaagtttataagaatagagctggaaataaggcatccaaggagaatgattggtatttggca
tataaggcttctcctggcaatctctctcagtttgaagacattctctttggtaacaatgat
atgtcagcttccattggtgttgtgggtgttaaaatgtccgcagttgatggccagagacag
gttggagttgggtatgtggattccatacagaggaaactaggactgtgtgaattccctgat
aatgatcagttctccaatcttgaggctctcctcatccagattggaccaaaggaatgtgtt
ttacccggaggagagactgctggagacatggggaaactgagacagattattcaaagagga
ggaattctgatcacagaaagaaaaaaagctgacttttccacaaaagacatttatcaggac
ctcaaccggttgttgaaaggcaaaaagggagagcagatgaatagtgctgtattgccagaa
atggaaaatcaggttgcagtttcatcactgtctgcggtaatcaagtttttagaactctta
tcagatgattccaactttggacagtttgaactgactacttttgacttcagccagtatatg
aaattggatattgcagcagtcagagcccttaacctttttcagggttctgttgaagatacc
tctggctctcagtctctggctgccttgctgaataagtgtaaaacccctcaaggacaaaga
cttgttaaccagtggattaagcagcctctcatggataagaacagaatagaggagagattg
aatttagtggaagcttttgtagaagatgcagaattgaggcagactttacaagaagattta
cttcgtcgattcccagatcttaaccgacttgccaagaagtttcaaagacaagcagcaaac
ttacaagattgttaccgactctatcagggtataaatcaactacctaatgttatacaggct
ctggaaaaacatgaaggaaaacaccagaaattattgttggcagtttttgtgactcccctt
actgatcttcgttctgacttctccaagtttcaggaaatgatagaaacaactttagatatg
gatcaggtggaaaaccatgaattccttgtaaaaccttcatttgatcctaatcttagtgaa
ttaagagaaataatgaatgacttggaaaagaagatgcagtcaacattaataagtgcagcc
agagatcttggcttggaccctggcaaacagattaaactggattccagtgcacagtttgga
tattactttcgtgtaacctgtaaggaagaaaaagtccttcgtaacaataaaaactttagt
actgtagatatccagaagaatggtgttaaatttaccaacagcaaattgacttctttaaat
gaagagtataccaaaaataaaacagaatatgaagaagcccaggatgccattgttaaagaa
attgtcaatatttcttcaggctatgtagaaccaatgcaaacactcaatgatgtgttagct
cagctagatgctgttgtcagctttgctcatgtgtcaaatggagcacctgttccatatgta
cgaccagctattttggagaaaggacaaggaagaattatattaaaagcatccaggcatgct
tgtgttgaagttcaagatgaaattgcatttattcctaatgacgtatactttgaaaaagat
aaacagatgttccacatcattactggccccaatatgggaggtaaatcaacatatattcga
caaactggggtgatagtactcatggcccaaattgggtgttttgtgccatgtgagtcagca
gaagtgtccattgtggactgcatcttagcccgggtaggggctggtgacagtcaattgaaa
ggagtctccacgttcatggctgaaatgttggaaactgcttctatcctcaggtctgcaacc
aaagattcattaataatcatagatgaattgggaagaggaacttctacctacgatggattt
gggttagcatgggctatatcagaatacattgcaacaaagattggtgctttttgcatgttt
gcaacccattttcatgaacttactgccttggccaatcagataccaactgttaataatcta
catgttacagcactcaccactgaagagaccttaactatgctttatcaggtgaagaaaggt
gtctgtgatcaaagttttgggattcatgttgcagagcttgctaatttccctaagcatgta
atagagtgtgctaaacagaaagccctggaacttgaggagtttcagtatattggagaatcg
caaggatatgatatcatggaaccagcagcaaagaagtgctatctggaaagagagcaaggt
gaaaaaattattcaggagttcctgtccaaggtgaaacaaatgccctttactgaaatgtca
gaagaaaacatcacaataaagttaaaacagctaaaagctgaagtaatagcaaagaataat
agctttgtaaatgaaatcatttcacgaataaaagttactacgtga

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