KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101152179
Entry
101152179         CDS       T02442                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X1
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04015  Rap1 signaling pathway
ggo04020  Calcium signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04520  Adherens junction
ggo04550  Signaling pathways regulating pluripotency of stem cells
ggo04714  Thermogenesis
ggo04810  Regulation of actin cytoskeleton
ggo04928  Parathyroid hormone synthesis, secretion and action
ggo05200  Pathways in cancer
ggo05205  Proteoglycans in cancer
ggo05215  Prostate cancer
ggo05218  Melanoma
ggo05224  Breast cancer
ggo05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101152179 (FGFR1)
   04014 Ras signaling pathway
    101152179 (FGFR1)
   04015 Rap1 signaling pathway
    101152179 (FGFR1)
   04020 Calcium signaling pathway
    101152179 (FGFR1)
   04151 PI3K-Akt signaling pathway
    101152179 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    101152179 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    101152179 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101152179 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    101152179 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    101152179 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101152179 (FGFR1)
   05205 Proteoglycans in cancer
    101152179 (FGFR1)
   05230 Central carbon metabolism in cancer
    101152179 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    101152179 (FGFR1)
   05215 Prostate cancer
    101152179 (FGFR1)
   05224 Breast cancer
    101152179 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ggo01001]
    101152179 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ggo04090]
    101152179 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:ggo00536]
    101152179 (FGFR1)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101152179 (FGFR1)
Protein kinases [BR:ggo01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   101152179 (FGFR1)
CD molecules [BR:ggo04090]
 Proteins
  101152179 (FGFR1)
Glycosaminoglycan binding proteins [BR:ggo00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   101152179 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 Ig_4 ABC1 V-set_CD47 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 101152179
NCBI-ProteinID: XP_018887679
Ensembl: ENSGGOG00000013080
LinkDB
Position
7:join(82971069..82971159,82998476..82998742,82999989..83000078,83000331..83000503,83002189..83002312,83003736..83003926,83006491..83006635,83008678..83008880,83010041..83010186,83010423..83010544,83010998..83011108,83012348..83012538,83013506..83013628,83013778..83013848,83014118..83014255,83014384..83014489,83014603..83014779)
AA seq 822 aa
MWSWKCLLFWAVLVTATLCTARPSPTLPEEAQPWGAPVEVESFLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL
GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL
VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG
RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD
KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSF
PDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcttctgggctgtgctggtcacagccacactctgcacc
gctaggccgtccccgaccttgcctgaagaagcccagccctggggagcccctgtggaagtg
gagtccttcctggtccaccccggtgacctgctgcagcttcgctgtcggctgcgggacgat
gtgcagagcatcaactggctgcgggacggggtgcagctggcggaaagcaaccgcacccgc
atcacaggggaggaggtggaggtgcaggactccgtgcccgcagactccggcctctatgct
tgcgtaaccagcagcccctcgggcagtgacaccacctacttctccgtcaatgtttcagat
gctctcccctcctcggaggatgatgatgatgatgatgactcctcttcagaggagaaagaa
acagataacaccaaaccaaaccgtatgcccgtagctccatattggacatccccggaaaag
atggaaaagaaattgcatgcagtgccggctgccaagacagtgaagttcaaatgcccttcc
agtgggaccccaaaccccacactgcgctggttgaaaaatggcaaagaattcaaacctgac
cacagaattggaggctacaaggtccgttatgccacctggagcatcataatggactccgtg
gtgccctctgacaagggcaactacacctgcattgtggagaatgagtacggcagcatcaac
cacacataccagctggatgtcgtggagcggtcccctcaccggcccatcctgcaagcaggg
ttgcctgccaacaagacagtcgccctgggtagcaacgtggagttcatgtgtaaggtgtac
agtgacccgcagccgcatatccagtggctaaagcacatcgaggtgaacgggagcaagatt
ggtccagacaacctgccttatgtccagatcttgaagactgctggagttaataccaccgac
aaagagatggaggtgcttcacttaagaaatgtctcctttgaggatgcaggggagtatacg
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgttctggaa
gccctggaagagaggccggcagtgatgacctcgcccctgtacctggagatcatcatctat
tgcacaggggccttcctcatctcctgcatggtggggtcggtcatcgtctacaagatgaag
agtggtaccaagaagagcgacttccacagccagatggctgtgcacaagctggccaagagc
atccctctgcgcagacaggtaacagtgtctgctgactccagtgcatccatgaactctggg
gttcttctggttcggccgtcacggctctcctccagtgggactcccatgctagcaggggtc
tctgagtatgagcttcccgaagaccctcgctgggagctgcctcgggacagactggtctta
ggcaaacccctgggagagggctgctttgggcaggtggtgttggcagaggctatcgggctg
gacaaggacaaacccaaccgtgtgaccaaagtggctgtgaagatgttgaagtcggacgca
acagagaaagacttgtcagacctgatctcggaaatggagatgatgaagatgatcgggaag
cataagaatatcatcaacctgctgggggcctgcacgcaggatggtcccttgtatgtcatc
gtggagtatgcctccaagggcaacctgcgggagtacctgcaggcccggaggcccccaggg
ctggaatactgctacaaccccagccacaacccagaggagcagctctcctccaaggacctg
gtgtcctgtgcctaccaggtggcccgaggcatggagtatctggcctccaagaagtgcata
caccgagacctggcagccaggaatgtcctggtgacagaggacaatgtgatgaagatagca
gactttggcctcgcacgggacattcaccacatcgactactataaaaagacaaccaacggc
cgactgcctgtgaagtggatggcgcccgaggcattatttgaccggatctacacccaccag
agtgatgtgtggtctttcggggtgctcctgtgggagatcttcactctgggcggctcccca
taccccggtgtgcctgtggaggagcttttcaagctgctgaaggagggtcaccgcatggac
aagcccagtaactgcaccaacgagctgtacatgatgatgcgggactgctggcatgcagtg
ccctcacagagacccaccttcaagcagctggtggaagacctggaccgcatcgtggccttg
acctccaaccaggagtacctggacctgtccatgcccctggaccagtactcccccagcttt
cccgacacccggagctctacgtgctcctcaggggaggattccgtcttctctcatgagccg
ctgcccgaggagccctgcctgccccgacacccagcccagcttgccaatggcggactcaaa
cgccgctga

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