KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101153465
Entry
101153465         CDS       T02442                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01523  Antifolate resistance
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04024  cAMP signaling pathway
ggo04062  Chemokine signaling pathway
ggo04064  NF-kappa B signaling pathway
ggo04066  HIF-1 signaling pathway
ggo04071  Sphingolipid signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04210  Apoptosis
ggo04211  Longevity regulating pathway
ggo04218  Cellular senescence
ggo04380  Osteoclast differentiation
ggo04613  Neutrophil extracellular trap formation
ggo04620  Toll-like receptor signaling pathway
ggo04621  NOD-like receptor signaling pathway
ggo04622  RIG-I-like receptor signaling pathway
ggo04623  Cytosolic DNA-sensing pathway
ggo04625  C-type lectin receptor signaling pathway
ggo04657  IL-17 signaling pathway
ggo04658  Th1 and Th2 cell differentiation
ggo04659  Th17 cell differentiation
ggo04660  T cell receptor signaling pathway
ggo04662  B cell receptor signaling pathway
ggo04668  TNF signaling pathway
ggo04722  Neurotrophin signaling pathway
ggo04917  Prolactin signaling pathway
ggo04920  Adipocytokine signaling pathway
ggo04926  Relaxin signaling pathway
ggo04931  Insulin resistance
ggo04932  Non-alcoholic fatty liver disease
ggo04933  AGE-RAGE signaling pathway in diabetic complications
ggo04936  Alcoholic liver disease
ggo05010  Alzheimer disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05030  Cocaine addiction
ggo05132  Salmonella infection
ggo05133  Pertussis
ggo05134  Legionellosis
ggo05135  Yersinia infection
ggo05140  Leishmaniasis
ggo05142  Chagas disease
ggo05145  Toxoplasmosis
ggo05146  Amoebiasis
ggo05152  Tuberculosis
ggo05160  Hepatitis C
ggo05161  Hepatitis B
ggo05162  Measles
ggo05163  Human cytomegalovirus infection
ggo05164  Influenza A
ggo05165  Human papillomavirus infection
ggo05166  Human T-cell leukemia virus 1 infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05168  Herpes simplex virus 1 infection
ggo05169  Epstein-Barr virus infection
ggo05170  Human immunodeficiency virus 1 infection
ggo05171  Coronavirus disease - COVID-19
ggo05200  Pathways in cancer
ggo05202  Transcriptional misregulation in cancer
ggo05203  Viral carcinogenesis
ggo05206  MicroRNAs in cancer
ggo05207  Chemical carcinogenesis - receptor activation
ggo05208  Chemical carcinogenesis - reactive oxygen species
ggo05212  Pancreatic cancer
ggo05215  Prostate cancer
ggo05220  Chronic myeloid leukemia
ggo05221  Acute myeloid leukemia
ggo05222  Small cell lung cancer
ggo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ggo05321  Inflammatory bowel disease
ggo05415  Diabetic cardiomyopathy
ggo05417  Lipid and atherosclerosis
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101153465 (NFKB1)
   04014 Ras signaling pathway
    101153465 (NFKB1)
   04064 NF-kappa B signaling pathway
    101153465 (NFKB1)
   04668 TNF signaling pathway
    101153465 (NFKB1)
   04066 HIF-1 signaling pathway
    101153465 (NFKB1)
   04071 Sphingolipid signaling pathway
    101153465 (NFKB1)
   04024 cAMP signaling pathway
    101153465 (NFKB1)
   04151 PI3K-Akt signaling pathway
    101153465 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101153465 (NFKB1)
   04218 Cellular senescence
    101153465 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101153465 (NFKB1)
   04620 Toll-like receptor signaling pathway
    101153465 (NFKB1)
   04621 NOD-like receptor signaling pathway
    101153465 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    101153465 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    101153465 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    101153465 (NFKB1)
   04660 T cell receptor signaling pathway
    101153465 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    101153465 (NFKB1)
   04659 Th17 cell differentiation
    101153465 (NFKB1)
   04657 IL-17 signaling pathway
    101153465 (NFKB1)
   04662 B cell receptor signaling pathway
    101153465 (NFKB1)
   04062 Chemokine signaling pathway
    101153465 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101153465 (NFKB1)
   04917 Prolactin signaling pathway
    101153465 (NFKB1)
   04926 Relaxin signaling pathway
    101153465 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101153465 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101153465 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    101153465 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101153465 (NFKB1)
   05202 Transcriptional misregulation in cancer
    101153465 (NFKB1)
   05206 MicroRNAs in cancer
    101153465 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    101153465 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101153465 (NFKB1)
   05203 Viral carcinogenesis
    101153465 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101153465 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101153465 (NFKB1)
   05221 Acute myeloid leukemia
    101153465 (NFKB1)
   05220 Chronic myeloid leukemia
    101153465 (NFKB1)
   05215 Prostate cancer
    101153465 (NFKB1)
   05222 Small cell lung cancer
    101153465 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101153465 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    101153465 (NFKB1)
   05161 Hepatitis B
    101153465 (NFKB1)
   05160 Hepatitis C
    101153465 (NFKB1)
   05171 Coronavirus disease - COVID-19
    101153465 (NFKB1)
   05164 Influenza A
    101153465 (NFKB1)
   05162 Measles
    101153465 (NFKB1)
   05168 Herpes simplex virus 1 infection
    101153465 (NFKB1)
   05163 Human cytomegalovirus infection
    101153465 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101153465 (NFKB1)
   05169 Epstein-Barr virus infection
    101153465 (NFKB1)
   05165 Human papillomavirus infection
    101153465 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101153465 (NFKB1)
   05135 Yersinia infection
    101153465 (NFKB1)
   05133 Pertussis
    101153465 (NFKB1)
   05134 Legionellosis
    101153465 (NFKB1)
   05152 Tuberculosis
    101153465 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101153465 (NFKB1)
   05145 Toxoplasmosis
    101153465 (NFKB1)
   05140 Leishmaniasis
    101153465 (NFKB1)
   05142 Chagas disease
    101153465 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    101153465 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101153465 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    101153465 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    101153465 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101153465 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    101153465 (NFKB1)
   05415 Diabetic cardiomyopathy
    101153465 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101153465 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    101153465 (NFKB1)
   04931 Insulin resistance
    101153465 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101153465 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101153465 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ggo03000]
    101153465 (NFKB1)
Transcription factors [BR:ggo03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    101153465 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 101153465
NCBI-ProteinID: XP_018881357
Ensembl: ENSGGOG00000009071
UniProt: G3RSI9
LinkDB
Position
3:join(122859124..122859162,122863433..122863511,122867460..122867500,122871468..122871566,122900569..122900717,122910456..122910619,122912460..122912618,122914108..122914212,122916449..122916540,122918259..122918397,122927032..122927175,122928501..122928590,122929747..122929941,122931127..122931268,122934502..122934616,122940103..122940304,122940757..122940926,122941256..122941358,122944183..122944307,122945663..122945729,122946058..122946230,122947054..122947210,122950064..122950224)
AA seq 969 aa
MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTADGPYLQILEQPKQRGFRFRY
VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE
DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ
AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD
FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV
QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF
HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG
EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ
DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE
DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAM
MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG
TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA
TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL
GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS
QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG
QEGPLEGKI
NT seq 2910 nt   +upstreamnt  +downstreamnt
atggcagaagatgatccatatttgggaaggcctgaacaaatgtttcatttggatccttct
ttgacccatacaatatttaatccagaagtatttcaaccacagatggcactgccaacagca
gatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttat
gtatgtgaaggcccatcccatggtggactacctggtgcctctagcgaaaagaacaagaag
tcttaccctcaggtcaaaatctgcaactatgtgggaccagcaaaggttattgttcagttg
gtcacaaatggaaaaaatatccacctgcatgcccacagcctggtgggaaaacactgtgag
gatgggatctgcactgtaactgctggacccaaggacatggtggtcggcttcgcaaacctg
ggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagag
gcgtgtataaggggctataatcctggactcttggtgcaccctgaccttgcctatttgcaa
gcagaaggtggaggggaccggcagctgggagatcgggaaaaagagctaatccgccaagca
gctctgcagcagaccaaggagatggacctcagcgtggtgcggctcatgtttacagctttt
cttccggatagcactggcagcttcacaaggcgcctggaacccgtggtatcagacgccatc
tatgacagtaaagcccccaatgcatccaacttgaaaattgtaagaatggacaggacagct
ggatgtgtgactggaggggaggaaatttatcttctctgtgacaaagttcagaaagatgac
atccagattcgattttatgaagaggaggaaaatggtggagtctgggaaggatttggagat
ttttcccccacagatgttcatagacaatttgccatcgtcttcaaaactccaaagtataaa
gatattaatattacaaaaccagcctctgtgtttgtccagcttcggaggaaatctgacttg
gaaactagtgaaccaaaacctttcctctactatcctgaaatcaaagataaagaagaagtg
cagaggaaacgtcagaagctcatgcccaatttttcggatagtttcggcggtggtagtggt
gctggagctggaggcggaggcatgtttggtagtggcggtggaggagggggcactggaagt
acaggtccagggtatagcttcccgcactatggatttcctacttatggtgggattaccttc
catcctggaactactaaatctaatgctgggatgaagcatggaaccatggacactgaatct
aaaaaggaccctgaaggttgtgacaaaagtgatgacaaaaacactgtaaacctctttggg
aaagttattgaaaccacagagcaagatcaggagcccagcgaggccaccgttgggaatggt
gaggtcactctaacgtatgcaacaggaacaaaagaagagagtgctggggttcaggataac
ctctttctagagaaggctatgcagcttgcaaagaggcatgccaatgccctttttgactac
gcggtgacaggagacgtgaagatgctgctggccgtccagcgccatctcactgctgtgcag
gatgagaatggggacagtgtcttacacttagcaatcatccaccttcattctcaacttgtg
agggatctactagaagtcacatctggtttgatttctgatgacattatcaacatgagaaat
gatctgtaccagacgcccttgcacttggcagtgatcactaagcaggaagatgtggtggag
gatttgctgagggctggggccgacctgagccttctggaccgcttgggtaactctgttttg
cacctagctgccaaagaaggacatgataaagttctcagtatcttactcaagcacaaaaag
gcagcactacttcttgaccaccccaacggggacggtctgaatgccattcatctagccatg
atgagcaatagcctgccatgtttgctgctgctggtggccgctggggccgacgtcaatgct
caggagcagaagtccgggcgcacagcactgcacctggctgtggagcacgacaacatctca
ttggcaggctgcctgctcctggagggtgatgcccatgtggacagtactacctacgatgga
accacacccctgcatatagcagctgggagagggtccaccaggctggcagctcttctcaaa
gcagcaggagcggatcccctggtggagaactttgagcctctctatgacctggatgactct
tgggaaaatgcaggagaggatgaaggagttgtgcctggaaccacgcctctagatatggct
accagctggcaggtatttgacatattaaatgggaaaccatatgagccagagtttacatct
gatgatttactagcacaaggagacatgaaacagctggctgaagatgtgaagctgcagctg
tataagttactagaaattcctgatccagacaaaaactgggctactctggcgcagaaatta
ggtctggggatacttaataatgccttccggctgagtcctgctccttccaaaacacttatg
gacaactatgaggtctctgggggtacagtcagagagctggtggaggccctgagacaaatg
ggctacaccgaagcaattgaagtgatccaggcagcctccagcccagtgaagaccacctct
caggcccactcgctgcctctctcgcctgcctccacaaggcagcagatagacgagctccga
gacagtgacagtgtctgcgacagcggcgtggagacatccttccgcaaactcagctttact
gagtctctgaccagtggtgcctcactgctaactctcaacaaaatgccccatgattatggg
caggaaggacctctagaaggcaaaatttag

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