KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101153728
Entry
101153728         CDS       T02442                                 
Symbol
GSTA4
Name
(RefSeq) glutathione S-transferase A4 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00480  Glutathione metabolism
ggo00980  Metabolism of xenobiotics by cytochrome P450
ggo00982  Drug metabolism - cytochrome P450
ggo00983  Drug metabolism - other enzymes
ggo01100  Metabolic pathways
ggo01524  Platinum drug resistance
ggo05200  Pathways in cancer
ggo05204  Chemical carcinogenesis - DNA adducts
ggo05207  Chemical carcinogenesis - receptor activation
ggo05208  Chemical carcinogenesis - reactive oxygen species
ggo05225  Hepatocellular carcinoma
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101153728 (GSTA4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101153728 (GSTA4)
   00982 Drug metabolism - cytochrome P450
    101153728 (GSTA4)
   00983 Drug metabolism - other enzymes
    101153728 (GSTA4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101153728 (GSTA4)
   05204 Chemical carcinogenesis - DNA adducts
    101153728 (GSTA4)
   05207 Chemical carcinogenesis - receptor activation
    101153728 (GSTA4)
   05208 Chemical carcinogenesis - reactive oxygen species
    101153728 (GSTA4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101153728 (GSTA4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101153728 (GSTA4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101153728 (GSTA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ggo02000]
    101153728 (GSTA4)
Enzymes [BR:ggo01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101153728 (GSTA4)
Transporters [BR:ggo02000]
 Other transporters
  Pores ion channels [TC:1]
   101153728 (GSTA4)
SSDB
Motif
Pfam: GST_C_3 GST_N GST_C GST_C_2 GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 101153728
NCBI-ProteinID: XP_004044256
Ensembl: ENSGGOG00000005376
UniProt: G3QRL1
LinkDB
Position
5:complement(join(70763362..70763484,70767468..70767599,70769353..70769494,70770337..70770469,70772249..70772300,70779052..70779138))
AA seq 222 aa
MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcagcaaggcccaagctccactatcccaacggaagaggccggatggagtccgtgaga
tgggttttagctgcggccggagtcgagtttgatgaagaatttctggaaacaaaagaacag
ttgtacaagttgcaggatggtaaccacctgctgttccaacaagtgcccatggttgaaatt
gacgggatgaagttggtacagacccgaagcattctccactacatagcagacaagcacaat
ctctttggcaagaacctcaaggagagaaccctgattgacatgtacgtggaggggacactg
gatctgctggaactgcttatcatgcatcctttcttaaaaccagatgatcaacaaaaggaa
gtggttaacatggcccagaaggctataattagatactttcctgtgtttgaaaagatttta
aggggtcacggacaaagctttcttgttggtaatcagctgagccttgcagatgtgatttta
ctccaaaccattttagctctagaagagaaaattcctaatatcctgtctgcatttcctttc
ctccaggagtacacagtgaaactaagtaatatccctacaattaagagattccttgaacct
ggcagcaagaagaagcctccccctgatgaaatttacgtgagaaccgtctacaacatcttt
aggccataa

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