KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101154382
Entry
101154382         CDS       T02442                                 
Symbol
TPO
Name
(RefSeq) thyroid peroxidase isoform X1
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00350  Tyrosine metabolism
ggo01100  Metabolic pathways
ggo04918  Thyroid hormone synthesis
ggo05320  Autoimmune thyroid disease
Module
ggo_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    101154382 (TPO)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    101154382 (TPO)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    101154382 (TPO)
Enzymes [BR:ggo01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     101154382 (TPO)
SSDB
Motif
Pfam: An_peroxidase EGF_CA Sushi FXa_inhibition EGF_3 EGF cEGF
Other DBs
NCBI-GeneID: 101154382
NCBI-ProteinID: XP_055234664
Ensembl: ENSGGOG00000004239
LinkDB
Position
12:complement(join(138431455..138431508,138433206..138433377,138453606..138453705,138466234..138466365,138473478..138473648,138474036..138474244,138476478..138476715,138482761..138482931,138485899..138486157,138493132..138493650,138512788..138512994,138515247..138515376,138531226..138531358,138534000..138534169,138543967..138544051,138551943..138552036))
AA seq 947 aa
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
RAYLPFAPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
LKALNAHWSADAVYQEARKVVGALHQIITLRDYVPRILGPEAFQQYVGPYEGYDSTANPT
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR
GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
MKALRDGDWFWWENRRIFTDAQRRELEKHSLSRVICDNTGLTRVPVDAFQVGKFPEDFES
CDSIPGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD
SGRLPRATWVSILLAALLIGGFAGLTSTVICRCHGPSPDNWTRVSHRTRTGTKSTLPISE
TGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
NT seq 2844 nt   +upstreamnt  +downstreamnt
atgagagcactcgctgtgctgtctgtcacgctggttatggcctgcacagaagccttcttc
cccttcatctcgagagggaaagaactcctttggggaaagcctgaggagtctcgtgtctct
agcgtcttggaggaaagcaagcgcctggtggacaccgccatgtacgccacgatgcagaga
aacctcaaaaaaagaggaatcctttctccagctcagcttctgtctttttccaaacttcct
gagccaacaagtggagtgattgcccgagcagcagagataatggaaacatcaatacaagcg
atgaaaagaaaagtcaacctgaaaactcagcaatcacagcatccaactgatgctttatca
gaagatctgctgagcatcattgcaaacatgtccggatgtctcccttacatgctgcccccc
aaatgcccaaacacttgcctggcgaacaaatacaggcccatcacaggagcttgcaacaac
agagaccaccccagatggggcgcctccaacacggccctggcacgatggctccctccagtc
tatgaggacggcttcagtcagccccgaggctggaaccccggcttcttgtacaacgggttc
ccactgcccccggtccgggaggtgacaagacatgtcattcaagtttcaaatgaggttgtc
acagatgatgaccgctattctgacctcctgatggcatggggacaatacatcgaccacgac
atcgcgttcacaccacagagcaccagcaaagctgccttcgggggaggggctgactgccag
atgacttgtgagaaccaaaacccatgttttcccatacaactcccggaggaggcccggccg
gccgcgggcaccgcctgtctgcccttctaccgctcttcggccgcctgcggcaccggggac
caaggcgcgctctttgggaacctgtccacggccaacccgcggcagcagatgaacgggttg
acctcgttcctggacgcgtccaccgtgtatggcagctccccggccctagagaggcagctg
cggaactggaccagtgccgaagggctgctccgcgtccacgcgcgcctccgggactccggc
cgcgcctacctgcccttcgcgccgccacgcgcgcctgcggcctgtgcgcccgagcccggc
atccccggagagacccgcgggccctgcttcctggccggagacggccgcgccagcgaggtc
ccctccctgacggcactgcacacgctgtggctgcgcgagcacaaccgcctggccgcggcg
ctcaaggccctcaatgcgcactggagcgcagacgccgtgtaccaggaggcgcgcaaggtc
gtgggcgctctgcaccagatcatcaccctgagggattacgtccccaggatcctgggaccc
gaggccttccagcagtacgtgggtccctatgaaggctatgactccaccgccaaccccact
gtgtccaacgtgttctccacagccgccttccgcttcggccacgccacgatccacccgctg
gtgaggaggctggacgccagcttccaggagcaccccgacctgcccgggctgtggctgcac
caggccttcttcagcccatggacactcctccgtggaggtggtttggacccactaatacga
ggccttcttgcaagaccagccaaactgcaggtgcaggatcagctgatgaacgaggagctg
acggaaaggctctttgtgctgtccaattccagcaccttggatctggcgtccatcaacctg
cagaggggccgggaccacgggctgccaggttacaatgagtggagggagttctgcggcctg
cctcgcctggagacccccgctgacctgagcacagccatcgccagcaggagcgtggccgac
aagatcctggacttgtacaagcatcctgacaacatcgatgtctggctgggaggcttagct
gaaaacttcctccccagggctcggacagggcccctgtttgcctgtctcattgggaagcag
atgaaggctctgcgggatggtgactggttttggtgggagaacaggcgcatcttcacggat
gcacagaggcgtgagctggagaagcactccctgtctcgggtcatctgtgacaacaccggc
ctcaccagggtgcccgtggatgccttccaagtcggcaaattccccgaagactttgagtct
tgtgacagcatccctggcatgaacctggaggcctggagggaaacctttcctcaagacgac
aagtgtggcttcccagagagcgtggagaatggggactttgtacactgtgaggagtctggg
aggcgcgtgctggtgtattcctgccggcacgggtatgagctccaaggccgggagcagctc
acttgcacccaggaaggatgggatttccagcctcccctctgcaaagatgtgaacgagtgt
gcagacggtgcccaccccccctgccacgcctctgcgaggtgcagaaacaccaagggcggc
ttccagtgcctctgcgcagacccctacgagttaggagacgatgggagaacctgcgtagac
tccgggaggctccctcgggcgacttgggtctccatcttgctggctgctctgctgatcgga
ggcttcgcaggtctcacctcgacggtgatttgcaggtgtcacgggccctctcccgataac
tggacacgtgtctcccacaggacacgcactggcactaaatccacactgcccatctcggag
acgggcggaggaactcccgagctgagatgcgggaagcaccaggccgtagggacctcaccg
cagcgggccgcagctcaggactcggagcaggagagtgctgggatggaaggccgggatact
cacaggctgccaagagccctctga

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