KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101154397
Entry
101154397         CDS       T02442                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X4
  KO
K05459  insulin-like growth factor 1
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01521  EGFR tyrosine kinase inhibitor resistance
ggo01522  Endocrine resistance
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04015  Rap1 signaling pathway
ggo04066  HIF-1 signaling pathway
ggo04068  FoxO signaling pathway
ggo04081  Hormone signaling
ggo04114  Oocyte meiosis
ggo04115  p53 signaling pathway
ggo04150  mTOR signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04152  AMPK signaling pathway
ggo04211  Longevity regulating pathway
ggo04213  Longevity regulating pathway - multiple species
ggo04510  Focal adhesion
ggo04550  Signaling pathways regulating pluripotency of stem cells
ggo04730  Long-term depression
ggo04750  Inflammatory mediator regulation of TRP channels
ggo04913  Ovarian steroidogenesis
ggo04914  Progesterone-mediated oocyte maturation
ggo04935  Growth hormone synthesis, secretion and action
ggo04960  Aldosterone-regulated sodium reabsorption
ggo05200  Pathways in cancer
ggo05202  Transcriptional misregulation in cancer
ggo05205  Proteoglycans in cancer
ggo05214  Glioma
ggo05215  Prostate cancer
ggo05218  Melanoma
ggo05224  Breast cancer
ggo05410  Hypertrophic cardiomyopathy
ggo05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101154397 (IGF1)
   04014 Ras signaling pathway
    101154397 (IGF1)
   04015 Rap1 signaling pathway
    101154397 (IGF1)
   04066 HIF-1 signaling pathway
    101154397 (IGF1)
   04068 FoxO signaling pathway
    101154397 (IGF1)
   04151 PI3K-Akt signaling pathway
    101154397 (IGF1)
   04152 AMPK signaling pathway
    101154397 (IGF1)
   04150 mTOR signaling pathway
    101154397 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101154397 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101154397 (IGF1)
   04115 p53 signaling pathway
    101154397 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101154397 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    101154397 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101154397 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    101154397 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    101154397 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101154397 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    101154397 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101154397 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    101154397 (IGF1)
   04213 Longevity regulating pathway - multiple species
    101154397 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101154397 (IGF1)
   05202 Transcriptional misregulation in cancer
    101154397 (IGF1)
   05205 Proteoglycans in cancer
    101154397 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    101154397 (IGF1)
   05218 Melanoma
    101154397 (IGF1)
   05215 Prostate cancer
    101154397 (IGF1)
   05224 Breast cancer
    101154397 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101154397 (IGF1)
   05414 Dilated cardiomyopathy
    101154397 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101154397 (IGF1)
   01522 Endocrine resistance
    101154397 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ggo04052]
    101154397 (IGF1)
Cytokines and neuropeptides [BR:ggo04052]
 Cytokines
  Growth factors (RTK binding)
   101154397 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 101154397
NCBI-ProteinID: XP_004053822
Ensembl: ENSGGOG00000004943
UniProt: A0A2I2Z8G5
LinkDB
Position
10:complement(join(117836353..117836412,117853292..117853473,117907849..117908005,117912535..117912597))
AA seq 153 aa
MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM
NT seq 462 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacaccatgtcctcctcgcatctcttctacctggcgctgtgcctgctc
accttcaccagctctgccacggctggaccagagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtatggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctaaggaggctggagatgtattgcgcacccctcaagcctgccaagtcagctcgctct
gtccgtgcccagcgccacaccgacatgcccaagacccagaaggaagtacatttgaagaac
gcaagtagagggagtgcaggaaacaagaactacaggatgtag

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