KEGG   Gorilla gorilla gorilla (western lowland gorilla): 129525268
Entry
129525268         CDS       T02442                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo03015  mRNA surveillance pathway
ggo04022  cGMP-PKG signaling pathway
ggo04024  cAMP signaling pathway
ggo04114  Oocyte meiosis
ggo04218  Cellular senescence
ggo04261  Adrenergic signaling in cardiomyocytes
ggo04270  Vascular smooth muscle contraction
ggo04390  Hippo signaling pathway
ggo04510  Focal adhesion
ggo04519  Cadherin signaling
ggo04611  Platelet activation
ggo04720  Long-term potentiation
ggo04728  Dopaminergic synapse
ggo04750  Inflammatory mediator regulation of TRP channels
ggo04810  Regulation of actin cytoskeleton
ggo04910  Insulin signaling pathway
ggo04921  Oxytocin signaling pathway
ggo04931  Insulin resistance
ggo05031  Amphetamine addiction
ggo05034  Alcoholism
ggo05168  Herpes simplex virus 1 infection
ggo05205  Proteoglycans in cancer
ggo05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    129525268 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    129525268 (PPP1CA)
   04024 cAMP signaling pathway
    129525268 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    129525268 (PPP1CA)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    129525268 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    129525268 (PPP1CA)
   04218 Cellular senescence
    129525268 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129525268 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129525268 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129525268 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129525268 (PPP1CA)
   04921 Oxytocin signaling pathway
    129525268 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129525268 (PPP1CA)
   04270 Vascular smooth muscle contraction
    129525268 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    129525268 (PPP1CA)
   04720 Long-term potentiation
    129525268 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129525268 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    129525268 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    129525268 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    129525268 (PPP1CA)
   05034 Alcoholism
    129525268 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    129525268 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    129525268 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ggo01009]
    129525268 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:ggo03021]
    129525268 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:ggo03019]
    129525268 (PPP1CA)
   03041 Spliceosome [BR:ggo03041]
    129525268 (PPP1CA)
Enzymes [BR:ggo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     129525268 (PPP1CA)
Protein phosphatases and associated proteins [BR:ggo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     129525268 (PPP1CA)
Transcription machinery [BR:ggo03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     129525268 (PPP1CA)
Messenger RNA biogenesis [BR:ggo03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     129525268 (PPP1CA)
Spliceosome [BR:ggo03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    129525268 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 129525268
NCBI-ProteinID: XP_055210602
UniProt: G3R3C0
LinkDB
Position
9:complement(join(75326838..75326948,75327025..75327159,75327243..75327466,75327864..75327968,75328989..75329219,75329368..75329499,75330029..75330083))
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggtctgtgcctg
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatacacggccagtactacgaccttctgcgactatttgagtatggcggt
ttccctcccgagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
attgcggccatagtggatgaaaagatcttctgctgccacggaggcctgtccccggacctg
cagtctatggagcagattcggcggatcatgcggcccacagacgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagacggctacgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaatgctggc
gccatgatgagtgtggacgagaccctcatgtgctctttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccgacccatcacc
ccaccccgcaattccgccaaagccaagaaatag

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