Gorilla gorilla gorilla (western lowland gorilla): 6742687
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Entry
6742687 CDS
T02442
Symbol
ND4, KEG83_p04
Name
(RefSeq) NADH dehydrogenase subunit 4
KO
K03881
NADH-ubiquinone oxidoreductase chain 4 [EC:
7.1.1.2
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00190
Oxidative phosphorylation
ggo01100
Metabolic pathways
ggo04714
Thermogenesis
ggo04723
Retrograde endocannabinoid signaling
ggo05010
Alzheimer disease
ggo05012
Parkinson disease
ggo05014
Amyotrophic lateral sclerosis
ggo05016
Huntington disease
ggo05020
Prion disease
ggo05022
Pathways of neurodegeneration - multiple diseases
ggo05208
Chemical carcinogenesis - reactive oxygen species
ggo05415
Diabetic cardiomyopathy
Module
ggo_M00142
NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
6742687 (ND4)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
6742687 (ND4)
09159 Environmental adaptation
04714 Thermogenesis
6742687 (ND4)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
6742687 (ND4)
09164 Neurodegenerative disease
05010 Alzheimer disease
6742687 (ND4)
05012 Parkinson disease
6742687 (ND4)
05014 Amyotrophic lateral sclerosis
6742687 (ND4)
05016 Huntington disease
6742687 (ND4)
05020 Prion disease
6742687 (ND4)
05022 Pathways of neurodegeneration - multiple diseases
6742687 (ND4)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
6742687 (ND4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
ggo03029
]
6742687 (ND4)
Enzymes [BR:
ggo01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
6742687 (ND4)
Mitochondrial biogenesis [BR:
ggo03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial DNA-encoded proteins
Mitochondrial respiratory chain complex I
6742687 (ND4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Proton_antipo_M
Oxidored_q5_N
Motif
Other DBs
NCBI-GeneID:
6742687
NCBI-ProteinID:
YP_002120667
UniProt:
G3S7Z8
LinkDB
All DBs
Position
MT:10184..11561
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AA seq
459 aa
AA seq
DB search
MLKLIAPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQINNNLFSYSLSFSSDP
LTTPLLMLTTWLLPLTIMASQRHLSNEPLSRKKLYLSMLISLQISLIMTFTATELIMFYI
FFEATLIPTLVIITRWGNQPERLNVGTYFLFYTLVGSLPLLIALIHTHNTLGSLNILLLT
LTAQELPNSWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMMLAAVLLKLGG
YGMMRLMLILNPLTKHMAYPFLALSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVVAA
ILIQTPWSFTGAVVLMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMALWWL
LASLANLALPPTINLLGELSVLVTTFSWSNTTLLLTGSNMLITALYSLYMFTTTQWGPLT
HHITNMKPSFTRENILMFMHLSPILLLSLNPDIITGFTS
NT seq
1378 nt
NT seq
+upstream
nt +downstream
nt
atgctaaaactaatcgccccaacaattatactactaccgctaacatgactctccaaaaaa
catataatttgaatcaacacaaccacccacagcctaatcatcagcatcattcccctacta
ttttttaaccaaattaataacaatctatttagttactccctatctttttcctccgacccc
ctaacgacccccctcctaatattaactacctgactcctaccccttacaattatagcaagc
cagcgccacctatccaacgaaccactatcacgaaaaaaactctatctctccatattaatc
tccctccaaatctccttaatcataacattcacagccacagaactaatcatattctatatc
ttcttcgaagccacacttatccctaccctagttatcatcacccgatgaggcaaccaaccc
gaacgtctaaatgtgggtacatacttcctattctacaccctagtaggatccctcccccta
cttatcgcattaatccacactcacaacaccttaggctcactaaatattctattactcacc
cttactgcccaagaactacctaactcctgagccaacaacttaatatgactggcatacaca
atagcctttatagtgaaaataccactttacgggctccacctatgactccctaaggcccat
gttgaggcccccattgctggctcaatgatgctcgctgcagtactcttaaaattaggtggc
tatggcataatacgcctcatactcattcttaaccccctaacaaaacacatagcttatcct
ttcctcgccctatctttatggggtataatcataacaagctccatctgcctacggcaaaca
gatttaaaatcgctcattgcatactcctcaattagccacatagcccttgtagtagcagct
atccttatccaaaccccctgaagcttcaccggcgcagttgttcttataattgcccacgga
cttacatcatcattattattctgcctagcaaactcaaactacgaacgaacccacagccgc
atcataattctctctcaaggactccaaaccctactcccactaatagccctttgatgactt
ctggcaagcctcgccaacctcgccttaccccccaccattaacctactaggagagctctcc
gtactagtaaccacattctcctgatcaaacaccacccttttacttacaggatctaacata
ctaattacagccctgtactccctttatatatttaccacaacacaatgaggcccactcaca
caccacatcaccaacataaaaccctcatttacacgagaaaacatcctcatattcatgcac
ctatcccccatcctcctcctatccctcaaccccgatattatcaccgggtttacctcct
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