Geobacillus kaustophilus: GK1058
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Entry
GK1058 CDS
T00217
Name
(GenBank) dehydrogenase E1 component, alpha subunit (lipoamide)
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
gka
Geobacillus kaustophilus
Pathway
gka00010
Glycolysis / Gluconeogenesis
gka00020
Citrate cycle (TCA cycle)
gka00620
Pyruvate metabolism
gka00785
Lipoic acid metabolism
gka01100
Metabolic pathways
gka01110
Biosynthesis of secondary metabolites
gka01120
Microbial metabolism in diverse environments
gka01200
Carbon metabolism
gka01210
2-Oxocarboxylic acid metabolism
Module
gka_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
gka00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
GK1058
00020 Citrate cycle (TCA cycle)
GK1058
00620 Pyruvate metabolism
GK1058
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GK1058
Enzymes [BR:
gka01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
GK1058
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
RNase_J_C
Motif
Other DBs
NCBI-ProteinID:
BAD75343
UniProt:
Q5L137
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All DBs
Position
1083115..1084224
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AA seq
369 aa
AA seq
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MGVKTSQFRFAEQLEKVAEQFPTFQILNEEGEIVNEEAMPELSDEQLKELMRRMVYTRIL
DQRSISLNRQGRLGFYAPTAGQEASQIASHFALEKEDFILPGYRDVPQIIWHGLPLYQAF
LFSRGHFHGNQIPEGVNVLPPQIIIGAQYIQAAGVALGLKMRGKKAVAITYTGDGGTSQG
DFYEGINFAGAFKAPAIFVVQNNRFAISTPVEKQTIAKTLAQKAVAAGIPGIQVDGMDPL
AVYAAVKAARERAINGEGPALIETLCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRF
RKFLEAKGLWSEEEENRVIEQAKEDIKEAIKKADETPKQKVTDLISIMFEELPANLKEQY
EIYKEKESK
NT seq
1110 nt
NT seq
+upstream
nt +downstream
nt
atgggtgtgaaaacctcccagtttcgatttgcggagcagctcgagaaagtagccgagcag
ttcccgacgtttcaaattttgaatgaagaaggcgaaatcgtcaacgaagaggcgatgccg
gagttaagcgatgagcagctgaaagagctgatgcgccgcatggtgtatacgcgcatactc
gaccagcgctccatttcgttgaaccgccaaggccgactcgggttttacgcgccgaccgcc
gggcaagaagcgagccaaatcgccagccattttgcgcttgagaaagaagatttcattttg
ccgggatatcgcgacgttccgcaaatcatttggcacgggcttccgctttatcaagcgttt
ttgttctcgcgcggccactttcatggcaaccaaattcctgaaggcgtcaacgtcttgccg
ccgcaaatcatcatcggcgcccaatacattcaagcggccggcgtggcgctcggcttgaaa
atgcggggcaaaaaggcggtggccattacatataccggcgatgggggcacatcgcaaggc
gacttttatgaagggatcaacttcgcgggggcgtttaaggcaccggccatctttgttgtg
caaaacaaccgctttgccatctcgacgccagtggagaagcaaacgatcgccaaaacattg
gcgcaaaaagcggtcgctgccggcattccgggcattcaagtcgacggcatggatccgctt
gcggtctacgccgcggtgaaagcagcccgcgaacgcgccattaacggcgaagggccggcg
ctcatcgaaacgctttgcttccgctacggtccgcacacgatgtccggcgacgatccgacg
cgctatcgttcgaaagaactcgaaaacgaatgggcgaaaaaagacccgcttgtccgcttc
cgcaagtttttagaagcgaaaggtttatggagcgaagaggaagaaaaccgcgtcatcgag
caggcgaaagaggacatcaaggaagcgatcaaaaaagcggacgaaacgccgaaacaaaaa
gtgaccgacttaatcagcatcatgttcgaagagctgccggcgaacttaaaagagcagtat
gaaatttataaagagaaggagtcgaagtaa
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