Gloeomargarita lithophora: GlitD10_0309
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Entry
GlitD10_0309 CDS
T09871
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
glt
Gloeomargarita lithophora
Pathway
glt00300
Lysine biosynthesis
glt00550
Peptidoglycan biosynthesis
glt01100
Metabolic pathways
glt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
glt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GlitD10_0309 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GlitD10_0309 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GlitD10_0309 (murF)
Enzymes [BR:
glt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GlitD10_0309 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AAA_30
LonC_helical
Motif
Other DBs
NCBI-ProteinID:
APB32616
UniProt:
A0A1J0A9J9
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Position
326146..327465
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AA seq
439 aa
AA seq
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MFRLEQLIAILGATPSQPLTGTVERITTDSRQVQPGDVFLALAGERWDGHDFVPQALDQG
AVAAIVQRPDLIAPDLPLLLVPDTLTAYQTLAAWWRKRFTIPVIAVTGSAGKTTTKELIA
AVLSTQGRVLKTSANENNDIGVPKTLLQLSRDDDYVVLEMGMRGRGEIARLAHIAQPDVG
VITTVGTAHIGRLGSRTAIAQAKCELFAHLQPQGTAIYWRENKLLHHTAKTVWEGRTCTY
GFTEGELQAQIVGNELISGNWRTPLPLAGEHNALNFLAALAVAKTLGVPWPEQPLALDLP
PGRSRWWELASDILLLDETYNASPEAVCATLKTLKQTPGQRHIAVLGAMRELGENSAPLH
AQVGTWVGELQYNYLILLNDPEILPLARAAKPVPVTVCDDHKQIIDHLNRLLQPGDRVLV
KASHSIGLGRVVQALTQGG
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
ttgtttcgattagaacaactgatagccattttgggggcaacccccagccaacccctcacc
ggcaccgttgagcgcattaccaccgatagccgtcaggttcaacctggggatgtattcctt
gccctggcgggggaacgctgggatgggcatgactttgtcccccaagcgttagaccagggg
gcggtggcggcgattgtccaacgaccggatttaattgcccccgatttgcccctgctcctg
gtacccgatacgctcacggcctaccaaaccctggccgcttggtggcgcaagcgattcact
atcccggtgattgctgtcaccggctcggcgggcaaaaccaccaccaaggaactgatcgcc
gccgtgctatccacccaggggcgggtgctaaaaacctcagccaatgaaaataatgacatc
ggcgtacccaaaaccctcctgcaactgagtcgggatgatgattacgttgtcctggagatg
gggatgcgggggcggggggaaattgcccgcttggcgcacattgcccagcccgatgtgggg
gtgattaccacggtggggacggcgcatattggacgactgggttcccgtacagccattgcc
caggccaaatgtgaactgtttgcccatctccagccccaggggacggccatttattggcgg
gaaaataaattattacatcatactgcaaaaaccgtatgggaaggcaggacttgcacctac
gggtttaccgagggggaattgcaggcgcagatcgtgggaaatgagctaatcagcgggaat
tggcggactcctttgcccctagcgggagaacataacgccctgaattttttggcggccttg
gcggtggcgaaaaccctgggcgttccctggccggagcaacctttggctctggatttaccc
cccgggcgcagtcgttggtgggaattggcctcggatattctcctgctggatgaaacctac
aacgccagccccgaagccgtttgcgctaccttgaaaaccctgaaacaaacccccggccaa
cgccatatcgccgtgctgggtgccatgcgggaattgggggaaaattccgccccactccat
gcccaggtggggacatgggttggtgaattacaatataattatttaatactgctcaatgac
ccggaaattttgcccctagcaagagcggccaagcccgttcctgtaacagtttgcgatgac
cacaagcaaatcattgaccatctaaataggctgttacaaccgggggatcgagtgctggtc
aaagcctcccattccatcggcctagggcgggtggtgcaggctctcacccagggcggttag
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