Geobacillus sp. Y4.1MC1: GY4MC1_3595
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Entry
GY4MC1_3595 CDS
T01348
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gmc
Geobacillus sp. Y4.1MC1
Pathway
gmc00300
Lysine biosynthesis
gmc00550
Peptidoglycan biosynthesis
gmc01100
Metabolic pathways
gmc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gmc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GY4MC1_3595
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GY4MC1_3595
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GY4MC1_3595
Enzymes [BR:
gmc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GY4MC1_3595
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
GntR
DUF2997
Motif
Other DBs
NCBI-ProteinID:
ADP76234
UniProt:
A0A7U3YI75
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All DBs
Position
complement(3586964..3588340)
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AA seq
458 aa
AA seq
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MITRTLRDIQAMVDGRGLADKFLDIMVHGVSTDTRTIQKGNLYVPLKGAKFDGHTFVQDA
LDKGASAVLWSETEGSPPADVPVIVVDDTLRALQRLAHRYRKQLSAKVIGITGSNGKTTT
KDIVAALLATTYKVQKTEGNLNNHIGVPLTLLRLEEDVEMAVVEMGMSNFGEIELLSNIA
EPDAAIITNIGESHLQELGSREGIAQAKLEILSGLKKNGLFVYNGDEPLLASRVAHLPLP
EHVLTFGQGNKNDYYPESVHLQANGMMFTIRQAANRSFFLPILGKHHVYNALAALAVARF
FGVSWENVQEALSRLQVTRMRMEVIETEKGWTVINDAYNANPTSMKAALQLLQELTGYKK
KMAVLGDMLELGDREVEFHQEIGAMLRPEIVDYVFTYGKLARHIALAAQPFFPDGRVNAY
EDKRALAKDLLAVVSPGDVILLKASRGMKLEELLPDLQ
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatcactcgtacattgcgcgatatacaggcgatggtggatggccgcgggcttgcggat
aagtttttggacatcatggttcatggggtttcaacggatacgcgaaccattcaaaaagga
aatttatatgttccgctgaaaggagcaaaatttgacgggcacacatttgtccaagacgcg
ctggataaaggagcgagcgctgtcctttggtcggaaacggaaggatctccgccggcagac
gtgccagtgattgtcgtggatgacacgttgcgcgcgctccagcgtcttgcgcatcggtac
cgcaagcagctttcagcaaaagtcattggcattaccgggagcaatggcaaaacaacgaca
aaagatatcgttgccgcattgttggccactacctataaagtgcaaaaaacggaaggaaat
ttaaacaaccatattggcgtgccattgacgctccttcgtctggaagaagacgtagaaatg
gccgtcgtcgaaatgggaatgagcaattttggcgaaattgaattattgtccaacatcgcc
gagccagatgcagcgattataacaaatattggcgagtcccatttgcaggaattaggttcg
cgtgaagggatcgcgcaagcaaaattagaaattttgtccggcttaaaaaagaacggcctt
ttcgtttataacggagacgagccattgctggcaagccgggttgcccatttgccgctgccg
gagcatgtgttgacgttcgggcaaggaaataaaaatgattattatccggagtcggtccat
ttgcaggcaaatggcatgatgtttaccattcgtcaagcggcaaatcgatctttttttctg
ccgattttagggaagcatcatgtatataacgcattggctgcgctcgctgtagcccgtttt
tttggcgtaagctgggagaacgtgcaagaggcgctttcgcgattgcaagtaacgcgcatg
cgcatggaagtcatcgaaacggaaaagggctggacggttattaatgatgcttacaacgcc
aatccgacatcgatgaaagcagctttgcaattgcttcaagagttgacaggatataagaaa
aaaatggctgtgttgggagacatgctggagcttggcgatcgggaagtggaatttcatcag
gaaattggcgcaatgctgcggccggaaatcgttgattatgtatttacgtatgggaaattg
gcacgccatattgcgcttgcggcgcagccgttctttcctgacgggcgcgtgaacgcttat
gaagataagcgggcattggcgaaagatttgctcgcggttgtttccccgggagatgtgatt
ttgctgaaggcgtcgcgcggtatgaagctggaagagctgcttcctgatttgcaatga
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