KEGG   Globicephala melas (long-finned pilot whale): 115846836
Entry
115846836         CDS       T11080                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
gmf  Globicephala melas (long-finned pilot whale)
Pathway
gmf04010  MAPK signaling pathway
gmf04014  Ras signaling pathway
gmf04015  Rap1 signaling pathway
gmf04024  cAMP signaling pathway
gmf04062  Chemokine signaling pathway
gmf04071  Sphingolipid signaling pathway
gmf04145  Phagosome
gmf04148  Efferocytosis
gmf04151  PI3K-Akt signaling pathway
gmf04310  Wnt signaling pathway
gmf04360  Axon guidance
gmf04370  VEGF signaling pathway
gmf04380  Osteoclast differentiation
gmf04510  Focal adhesion
gmf04520  Adherens junction
gmf04530  Tight junction
gmf04613  Neutrophil extracellular trap formation
gmf04620  Toll-like receptor signaling pathway
gmf04650  Natural killer cell mediated cytotoxicity
gmf04662  B cell receptor signaling pathway
gmf04664  Fc epsilon RI signaling pathway
gmf04666  Fc gamma R-mediated phagocytosis
gmf04670  Leukocyte transendothelial migration
gmf04722  Neurotrophin signaling pathway
gmf04810  Regulation of actin cytoskeleton
gmf04932  Non-alcoholic fatty liver disease
gmf04933  AGE-RAGE signaling pathway in diabetic complications
gmf04972  Pancreatic secretion
gmf05014  Amyotrophic lateral sclerosis
gmf05020  Prion disease
gmf05022  Pathways of neurodegeneration - multiple diseases
gmf05100  Bacterial invasion of epithelial cells
gmf05132  Salmonella infection
gmf05135  Yersinia infection
gmf05163  Human cytomegalovirus infection
gmf05167  Kaposi sarcoma-associated herpesvirus infection
gmf05169  Epstein-Barr virus infection
gmf05170  Human immunodeficiency virus 1 infection
gmf05200  Pathways in cancer
gmf05203  Viral carcinogenesis
gmf05205  Proteoglycans in cancer
gmf05208  Chemical carcinogenesis - reactive oxygen species
gmf05210  Colorectal cancer
gmf05211  Renal cell carcinoma
gmf05212  Pancreatic cancer
gmf05231  Choline metabolism in cancer
gmf05415  Diabetic cardiomyopathy
gmf05416  Viral myocarditis
gmf05417  Lipid and atherosclerosis
gmf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    115846836 (RAC1)
   04014 Ras signaling pathway
    115846836 (RAC1)
   04015 Rap1 signaling pathway
    115846836 (RAC1)
   04310 Wnt signaling pathway
    115846836 (RAC1)
   04370 VEGF signaling pathway
    115846836 (RAC1)
   04071 Sphingolipid signaling pathway
    115846836 (RAC1)
   04024 cAMP signaling pathway
    115846836 (RAC1)
   04151 PI3K-Akt signaling pathway
    115846836 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    115846836 (RAC1)
   04148 Efferocytosis
    115846836 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    115846836 (RAC1)
   04520 Adherens junction
    115846836 (RAC1)
   04530 Tight junction
    115846836 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    115846836 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    115846836 (RAC1)
   04620 Toll-like receptor signaling pathway
    115846836 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    115846836 (RAC1)
   04662 B cell receptor signaling pathway
    115846836 (RAC1)
   04664 Fc epsilon RI signaling pathway
    115846836 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    115846836 (RAC1)
   04670 Leukocyte transendothelial migration
    115846836 (RAC1)
   04062 Chemokine signaling pathway
    115846836 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    115846836 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    115846836 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    115846836 (RAC1)
   04380 Osteoclast differentiation
    115846836 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    115846836 (RAC1)
   05205 Proteoglycans in cancer
    115846836 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    115846836 (RAC1)
   05203 Viral carcinogenesis
    115846836 (RAC1)
   05231 Choline metabolism in cancer
    115846836 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    115846836 (RAC1)
   05212 Pancreatic cancer
    115846836 (RAC1)
   05211 Renal cell carcinoma
    115846836 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    115846836 (RAC1)
   05163 Human cytomegalovirus infection
    115846836 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    115846836 (RAC1)
   05169 Epstein-Barr virus infection
    115846836 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    115846836 (RAC1)
   05135 Yersinia infection
    115846836 (RAC1)
   05100 Bacterial invasion of epithelial cells
    115846836 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    115846836 (RAC1)
   05020 Prion disease
    115846836 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    115846836 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    115846836 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    115846836 (RAC1)
   05415 Diabetic cardiomyopathy
    115846836 (RAC1)
   05416 Viral myocarditis
    115846836 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    115846836 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    115846836 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gmf04131]
    115846836 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gmf04147]
    115846836 (RAC1)
   04031 GTP-binding proteins [BR:gmf04031]
    115846836 (RAC1)
Membrane trafficking [BR:gmf04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    115846836 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    115846836 (RAC1)
  Macropinocytosis
   Ras GTPases
    115846836 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    115846836 (RAC1)
Exosome [BR:gmf04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   115846836 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   115846836 (RAC1)
  Exosomal proteins of colorectal cancer cells
   115846836 (RAC1)
  Exosomal proteins of bladder cancer cells
   115846836 (RAC1)
GTP-binding proteins [BR:gmf04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    115846836 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 115846836
NCBI-ProteinID: XP_030701913
LinkDB
Position
15:complement(4624926..4646150)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtaggtaaaacttgcctcctg
atcagttatacgaccaatgcctttcctggagagtatatccccactgtcttcgacaactat
tctgccaatgttatggtggatggaaaaccggtgaatctgggcttgtgggatacagctgga
caagaagattatgaccgattacgtcccctatcctatccgcaaacggatgtattcttgatt
tgcttttctcttgtgagtcctgcatcatttgaaaatgttcgtgcaaagtggtaccctgaa
gtgcgacaccactgtcccaacactcctatcatcctggtggggacgaaacttgatctgagg
gatgataaagacacgattgagaaactgaaggagaagaagctgacacccatcacctacccg
cagggcttggccatggccaaggagatcggtgccgtcaaatacctggagtgctcggcgctc
acgcagcgaggtcttaagacggtgtttgatgaagctatccgggcggttctctgcccgccc
cccgtcaagaagaggaagagaaaatgcctgctgttgtga

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