Globicephala melas (long-finned pilot whale): 115851082
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Entry
115851082 CDS
T11080
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC isoform X1
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf00230
Purine metabolism
gmf00670
One carbon pool by folate
gmf01100
Metabolic pathways
gmf01523
Antifolate resistance
Module
gmf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
115851082 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
115851082 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
115851082 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gmf04147
]
115851082 (ATIC)
Enzymes [BR:
gmf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
115851082 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
115851082 (ATIC)
Exosome [BR:
gmf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
115851082 (ATIC)
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GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
115851082
NCBI-ProteinID:
XP_030708679
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Position
7:complement(21916720..21947651)
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AA seq
592 aa
AA seq
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MAPGQLALLSVSDKTGLVEFARNLASVGLHLIASGGTAKALRDAGLAVRDVSEVTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFAKTVASPAVTVEVA
VEQIDIGGVTLLRAAAKNHTRVTVVCEPEDYAAVSSEMQGSDSKDTSLETRRQLALKAFT
HTARYDEAISDYFRKEYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGVPLSEDEAKVCMVYDMYETLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEDEALKLLSKKKNG
NYCVLQMDQSYSPDENEVRTLFGLRLSQKRNNSVINRSLFSNIVTKNKDLPESALRDLTV
ATIAVKYTQSNSVCYARDGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEQVPELLTEAEKREWVDKLSEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSTADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgccttattgagtgtctctgacaaaaccggccttgtggaattt
gccaggaacctagcttctgtgggtttgcatctgatcgcttctggagggactgcaaaagct
ctcagagatgctggtctggcagtcagagacgtctctgaggtaactggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggcatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtt
tgtaatctgtatccctttgcaaagacggtggcttctccggctgtaactgttgaagtggcg
gttgagcaaattgatattgggggagtaaccctgctgagagcggcagccaaaaaccacact
cgagtgacagtagtgtgtgaaccagaggactacgcggctgtgtcctcagagatgcagggc
tccgacagcaaagacacatctttggagacaagacgccagttagccttgaaggctttcact
catacggcacgatatgatgaagcaatttcagattacttcaggaaagaatatagtaaagga
atatctcagatgcccttgaggtatggaatgaaccctcatcaaactcctgcccagttatat
accctgaagcccaagctcccaatcacagttttgaatggagcccctggatttatcaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcca
gccgctgcctctttcaaacatgtcagcccggcaggcgctgctgttggagttccactcagt
gaagatgaagccaaagtctgcatggtctatgatatgtacgaaacgctcacacccatatcc
actgcatatgcaagagcaagaggggctgataggatgtcttcctttggtgattttgtcgca
ttatctgatgtttgtgatgtccctactgccaaaattatctctagagaggtatctgatggt
attattgccccgggatatgaagatgaagctttgaaattactttctaagaagaaaaatggg
aactactgtgttcttcagatggaccagtcttacagtccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagccagaagagaaataatagtgtcatcaacaggtcattattt
agcaacattgttaccaagaataaagatttgccggaatctgcgctcagagacctcactgtg
gccaccattgctgtcaagtatactcagtctaactccgtgtgctatgccagggacgggcag
gttattggcattggagctggacagcagtctcggatacactgcacacgccttgccggggat
aaggcaaactattggtggcttagacatcacccacaagtgctttccatgaagtttaaaact
ggagtgaagagagcagaaatctccaacgccatcgatcagtatgttactggaaccatcgga
gagggtgaagatttgatcaagtggaaggcactgtttgagcaggtccccgagttattaacc
gaggcagagaagagggaatgggttgacaaacttagtgaagtttccatcagctctgatgcc
ttctttcctttccgggacaatgtagacagagctaaaaggagtggcgtggcctacatcgct
gccccttccggttccactgctgacaaagttgtgatcgaggcttgcgatgagctgggaata
atcctcgctcacacgaatctccggctcttccatcactga
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