Globicephala melas (long-finned pilot whale): 115851851
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Entry
115851851 CDS
T11080
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase 3
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf00220
Arginine biosynthesis
gmf00330
Arginine and proline metabolism
gmf01100
Metabolic pathways
gmf04020
Calcium signaling pathway
gmf04022
cGMP-PKG signaling pathway
gmf04066
HIF-1 signaling pathway
gmf04071
Sphingolipid signaling pathway
gmf04151
PI3K-Akt signaling pathway
gmf04370
VEGF signaling pathway
gmf04371
Apelin signaling pathway
gmf04611
Platelet activation
gmf04915
Estrogen signaling pathway
gmf04921
Oxytocin signaling pathway
gmf04926
Relaxin signaling pathway
gmf04931
Insulin resistance
gmf04933
AGE-RAGE signaling pathway in diabetic complications
gmf05415
Diabetic cardiomyopathy
gmf05417
Lipid and atherosclerosis
gmf05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
115851851 (NOS3)
00330 Arginine and proline metabolism
115851851 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
115851851 (NOS3)
04371 Apelin signaling pathway
115851851 (NOS3)
04066 HIF-1 signaling pathway
115851851 (NOS3)
04020 Calcium signaling pathway
115851851 (NOS3)
04071 Sphingolipid signaling pathway
115851851 (NOS3)
04022 cGMP-PKG signaling pathway
115851851 (NOS3)
04151 PI3K-Akt signaling pathway
115851851 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
115851851 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
115851851 (NOS3)
04921 Oxytocin signaling pathway
115851851 (NOS3)
04926 Relaxin signaling pathway
115851851 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
115851851 (NOS3)
05418 Fluid shear stress and atherosclerosis
115851851 (NOS3)
05415 Diabetic cardiomyopathy
115851851 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
115851851 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
115851851 (NOS3)
Enzymes [BR:
gmf01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
115851851 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DEC-1_N
Motif
Other DBs
NCBI-GeneID:
115851851
NCBI-ProteinID:
XP_030710076
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Position
9:complement(6085198..6103402)
Genome browser
AA seq
1205 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQGPASPAPEPSRAPAPAPPPAPDHSPAPNSPQ
LTRPPEGPKFPRVKNWEAGSITYDTLCAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQGPP
PPEQLLSQARDFINQYYSSIKRSGSQAHKERLQEVEAEVAATGTYQLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHVKYATNRGNLRSAITVFPQRALGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQTPDE
APELFVLPPELVLEVPLEHPTLEWFSALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPD
PWKGSTAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAQA
AAQDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATVLLVENLQSSKSTRAT
ILVRLDTGSQEGLQYQPGDHIGICPPNRPGLVEALMSRVEDPPPPTESVAVEQLEKGSPG
GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFGRVLTAFS
REPNSPKTYVQDILRSELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHMRGAVPWAFDPPGP
DTPGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggccaggagcccgggccaccctgcggcctggggctgggg
ctgggcctcgggctgtgcagcaagcagggcccggcctccccagcgcccgagcccagccgg
gcaccggcacccgcacccccgcccgcgccagaccacagcccggctcccaacagcccccag
ctaacccggcctccagaggggcccaagttccctcgcgtcaagaactgggaggcggggagc
atcacctacgacactctgtgtgcgcaatcacagcaggacgggccctgcacccccagacgc
tgcctgggctctctggtgtttccacggaaactgcagagccgaccctcccagggccctccg
ccccctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagcggctcccaggctcacaaggagcggcttcaggaagtggaagccgaggtggcg
gccacaggcacctaccagcttcgtgagagcgagctggtgttcggggccaagcaggcctgg
cgcaacgccccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgacgcg
cgggattgcagctctgcacaggagatgttcacctacatctgcaaccacgtcaagtatgcc
accaaccggggcaacctccgttcggccatcacggtgttcccccagcgcgctctgggccgc
ggagacttccgcatctggaacagccaactggtgcgctacgcgggctacaggcagcaggac
ggctccgtgaggggggacccagccaacgtggagatcaccgagctctgcatccagcacggc
tggaccccaggaaacggccgctttgatgtgctgcccctgctgctccagaccccagatgag
gctccagagctctttgttctgccccccgaactggtcctcgaggtccccctggagcacccc
acgctggagtggttctcggccctgggcctgcgctggtacgccctcccagcagtgtccaac
atgctactggaaattgggggcctggagttccctgcagcccccttcagcggctggtacatg
agcacggagattggcatgcgggacctgtgtgatccccaccgctacaacatcctggaggac
gtggccgtctgcatggacctggatacccggaccacctcatccctgtggaaagataaggca
gccgtggaaatcaacttggctgtgctgcacagttaccagcttgccaaagtgaccattgtg
gaccaccacgctgccacggcctccttcatgaagcacctggagaacgagcagaaggccagg
gggggctgccctgccgactgggcctggatcgtgccccccatctcgggcagcctcacccca
gtcttccatcaggagatggtcaactatgtcctgtcccctgctttccgctaccagccagac
ccctggaaggggagcacagccaagggcaccggcatcaccaggaagaagacctttaaggaa
gtggccaatgcggtgaagatctctgcctcactcatgggcaccgtgatggcgaagcgagtg
aaggcgacgattctgtacgcctccgagaccggccgggcccagagctacgcacagcagctg
gggaggctcttccggaaggccttcgaccctcgggtcctgtgcatggatgagtatgacgtg
gtgtccctggagcacgagacgctggtgttggtggtgaccagcacctttgggaatggtgat
cccccagagaatggagagagttttgcggcagccctgatggagatgtcgggcccctacaac
agctcccctcggccagagcaacacaagagttacaaaatccgcttcaacagcgtctcctgc
tcagacccgctggtgtcctcctggcggcggaagaggaaggagtccagtaacaccgacagc
gcaggggcgctggggaccctcaggttctgtgtgtttgggctgggctcccgggcgtacccc
catttctgcgcctttgctcgtgcggtggacacgcggctggaagagctgggaggggagcgg
ctgcttcagctgggccagggcgatgagctgtgcggccaggaggaggccttccgtggctgg
gcccaggctgccttccaggcctcctgtgagacgttctgcgtgggggaggatgcccaggcc
gcggcccaggacatcttcagccccaaacggagctggaaacgccagaggtaccggctgagc
gcccaggccgagggcctccagctgctgccaggcctgatccacgtgcacaggcggaagatg
ttccaggccacagtcctcttggtggaaaacctacaaagcagcaagtccacccgggccacg
atcctggtgcgcctggacactggaagccaggaggggctccagtaccagccgggggaccac
ataggcatctgcccgcccaaccggccggggctcgtggaggcgctgatgagccgcgtggag
gacccgccgccgcccaccgagtctgtggcagtggagcaactggagaagggcagcccaggt
ggccctcctcccggctgggtgcgggacccccggctgcccccgtgtacgctgcgccaggct
ctcacctttttcctggacatcacctccccgcccagccctcaacttcttcgtctgctcagc
accctggctgaagagcccagtgaacagcaagagctcgagaccctcagccaggacccccgg
cgctacgaggagtggaagtggttccgctgccccaccctgctggaggtgctcgagcagttt
ccatccgtggcactgcctgccccactgcttctcacccagctgcccctgctccagccccgg
tactactcggtcagctcagcacccagcacccatccaggagagatccacctcacagtagct
gtgctggcatacaggactcaagatgggctgggtcccctgcactatggagtctgctccacg
tggctgagccaactcaaggctggagaccccgtaccctgcttcatcaggggggctccctcc
ttccggctgccgcctgatcccagcttgccctgcatcctcgtgggcccgggcactggcatc
gcccccttccggggattttggcaggagcggctacacgacatcgagagcaaagggctgcag
cctgcccccatgaccttggtgttcggctgccggtgctcccagctcgaccatctctaccgc
gaggaggtgcaggatgcccagcagcgcggggtgttcggccgcgtcctcaccgccttctcc
agggaacccaacagccctaagacctacgtgcaggacatcctgcggtcggagctggctgct
gaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcacc
atggcaaccagcgtcctgcagacggtgcagcgtatcttggcgacagagggcgacatggag
ctggatgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggac
attttcgggctcacgctgcgcacccaggaagtgacaagccgcatacgcacccagagcttt
tccttgcaggagcggcatatgcggggcgcagtgccctgggcgttcgacccgcccggccca
gacacccctggcccctga
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