Globicephala melas (long-finned pilot whale): 115854101
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Entry
115854101 CDS
T11080
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf01521
EGFR tyrosine kinase inhibitor resistance
gmf01522
Endocrine resistance
gmf04010
MAPK signaling pathway
gmf04012
ErbB signaling pathway
gmf04014
Ras signaling pathway
gmf04062
Chemokine signaling pathway
gmf04068
FoxO signaling pathway
gmf04072
Phospholipase D signaling pathway
gmf04150
mTOR signaling pathway
gmf04151
PI3K-Akt signaling pathway
gmf04510
Focal adhesion
gmf04540
Gap junction
gmf04630
JAK-STAT signaling pathway
gmf04650
Natural killer cell mediated cytotoxicity
gmf04660
T cell receptor signaling pathway
gmf04662
B cell receptor signaling pathway
gmf04664
Fc epsilon RI signaling pathway
gmf04714
Thermogenesis
gmf04722
Neurotrophin signaling pathway
gmf04810
Regulation of actin cytoskeleton
gmf04910
Insulin signaling pathway
gmf04912
GnRH signaling pathway
gmf04915
Estrogen signaling pathway
gmf04917
Prolactin signaling pathway
gmf04926
Relaxin signaling pathway
gmf04935
Growth hormone synthesis, secretion and action
gmf05034
Alcoholism
gmf05160
Hepatitis C
gmf05161
Hepatitis B
gmf05163
Human cytomegalovirus infection
gmf05165
Human papillomavirus infection
gmf05200
Pathways in cancer
gmf05205
Proteoglycans in cancer
gmf05206
MicroRNAs in cancer
gmf05207
Chemical carcinogenesis - receptor activation
gmf05208
Chemical carcinogenesis - reactive oxygen species
gmf05210
Colorectal cancer
gmf05211
Renal cell carcinoma
gmf05213
Endometrial cancer
gmf05214
Glioma
gmf05215
Prostate cancer
gmf05220
Chronic myeloid leukemia
gmf05221
Acute myeloid leukemia
gmf05223
Non-small cell lung cancer
gmf05224
Breast cancer
gmf05225
Hepatocellular carcinoma
gmf05226
Gastric cancer
gmf05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
115854101 (SOS1)
04012 ErbB signaling pathway
115854101 (SOS1)
04014 Ras signaling pathway
115854101 (SOS1)
04630 JAK-STAT signaling pathway
115854101 (SOS1)
04068 FoxO signaling pathway
115854101 (SOS1)
04072 Phospholipase D signaling pathway
115854101 (SOS1)
04151 PI3K-Akt signaling pathway
115854101 (SOS1)
04150 mTOR signaling pathway
115854101 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
115854101 (SOS1)
04540 Gap junction
115854101 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
115854101 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
115854101 (SOS1)
04660 T cell receptor signaling pathway
115854101 (SOS1)
04662 B cell receptor signaling pathway
115854101 (SOS1)
04664 Fc epsilon RI signaling pathway
115854101 (SOS1)
04062 Chemokine signaling pathway
115854101 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
115854101 (SOS1)
04912 GnRH signaling pathway
115854101 (SOS1)
04915 Estrogen signaling pathway
115854101 (SOS1)
04917 Prolactin signaling pathway
115854101 (SOS1)
04926 Relaxin signaling pathway
115854101 (SOS1)
04935 Growth hormone synthesis, secretion and action
115854101 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
115854101 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
115854101 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
115854101 (SOS1)
05206 MicroRNAs in cancer
115854101 (SOS1)
05205 Proteoglycans in cancer
115854101 (SOS1)
05207 Chemical carcinogenesis - receptor activation
115854101 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
115854101 (SOS1)
05231 Choline metabolism in cancer
115854101 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
115854101 (SOS1)
05225 Hepatocellular carcinoma
115854101 (SOS1)
05226 Gastric cancer
115854101 (SOS1)
05214 Glioma
115854101 (SOS1)
05221 Acute myeloid leukemia
115854101 (SOS1)
05220 Chronic myeloid leukemia
115854101 (SOS1)
05211 Renal cell carcinoma
115854101 (SOS1)
05215 Prostate cancer
115854101 (SOS1)
05213 Endometrial cancer
115854101 (SOS1)
05224 Breast cancer
115854101 (SOS1)
05223 Non-small cell lung cancer
115854101 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
115854101 (SOS1)
05160 Hepatitis C
115854101 (SOS1)
05163 Human cytomegalovirus infection
115854101 (SOS1)
05165 Human papillomavirus infection
115854101 (SOS1)
09165 Substance dependence
05034 Alcoholism
115854101 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
115854101 (SOS1)
01522 Endocrine resistance
115854101 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
115854101
NCBI-ProteinID:
XP_030713735
LinkDB
All DBs
Position
12:59144651..59293230
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSVSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagttactaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaac
gatgtagaaaatatatttagccgtatagtggatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agttgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgctctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagagtatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccaatgagtacaagcatgcttttgagataattttaaaagat
gaaaatagcgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaagaaaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctacgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcgatgaaaaagtgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcaccccctaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaggaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtatacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagt
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagatcatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgatattcagtatcagac
cggacctctatatcagatcctcctgaaagccctcccttattacctccacgagaacccgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgctcattcttcctga
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integrated database retrieval system
