Globicephala melas (long-finned pilot whale): 115854476
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Entry
115854476 CDS
T11080
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf03060
Protein export
gmf04141
Protein processing in endoplasmic reticulum
gmf04612
Antigen processing and presentation
gmf04918
Thyroid hormone synthesis
gmf05012
Parkinson disease
gmf05014
Amyotrophic lateral sclerosis
gmf05020
Prion disease
gmf05022
Pathways of neurodegeneration - multiple diseases
gmf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
115854476 (HSPA5)
04141 Protein processing in endoplasmic reticulum
115854476 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
115854476 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
115854476 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
115854476 (HSPA5)
05014 Amyotrophic lateral sclerosis
115854476 (HSPA5)
05020 Prion disease
115854476 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
115854476 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
115854476 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
gmf03110
]
115854476 (HSPA5)
04131 Membrane trafficking [BR:
gmf04131
]
115854476 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gmf04147
]
115854476 (HSPA5)
Enzymes [BR:
gmf01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
115854476 (HSPA5)
Chaperones and folding catalysts [BR:
gmf03110
]
Heat shock proteins
HSP70 / DNAK
115854476 (HSPA5)
Membrane trafficking [BR:
gmf04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
115854476 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
115854476 (HSPA5)
Exosome [BR:
gmf04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
115854476 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
115854476 (HSPA5)
Exosomal proteins of colorectal cancer cells
115854476 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
115854476
NCBI-ProteinID:
XP_030714540
LinkDB
All DBs
Position
6:10632165..10637111
Genome browser
AA seq
655 aa
AA seq
DB search
MKPSLVAAVLLLMLGAARPEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagccctccctggtggctgcggtgctgctgctgatgctcggcgcggcgcggccggag
gaggaggacaagaaggaggacgtgggcacggtggtcggtatcgacctgggcaccacgtac
tcctgcgtcggggtgttcaaaaacggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatcctgagaacacggtcttcgacgccaagcggctcatc
ggccgtacatggaacgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccgtacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgccgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcctatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctgggttgaatgttatgaggatcatc
aatgagcctacagcagctgctattgcttacggcctggataagagggaaggggagaagaac
atcctggtgtttgacttgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagttgtggccactaatggagatactcatttgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaagctgtacaaaaagaaaactggcaaagatgttcgg
aaagacaacagagctgtgcagaaactccggcgtgaggttgaaaaggccaaacgggccctg
tcttctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctct
gagacccttactcgggccaaatttgaagagctaaacatggatctgttccgttctaccatg
aagcctgtccagaaagtgctggaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactagaatcccaaagattcaacaactggttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtagcgtatggtgctgct
gtccaggctggtgtactctctggtgatcaagatacaggtgatctggtattgcttgatgta
tgtccccttacacttggtattgaaaccgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcagcca
actgttaccatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctg
ggaacttttgatctgactggaattcctcctgctccccgtggggttccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataaaatcacaattacaaatgaccaaaatcgcctgacacctgaagaaattgaa
aggatggtcaatgatgctgagaagttcgctgaggaagacaaaaagctcaaggagcgcatt
gacaccagaaatgagttggaaagctatgcctactctctaaagaatcagattggagataaa
gaaaagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctggaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccaactggtgatgaggaaccagcagacaaagacgagttgtag
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