KEGG   Globicephala melas (long-finned pilot whale): 115858048
Entry
115858048         CDS       T11080                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
gmf  Globicephala melas (long-finned pilot whale)
Pathway
gmf04010  MAPK signaling pathway
gmf04020  Calcium signaling pathway
gmf04022  cGMP-PKG signaling pathway
gmf04114  Oocyte meiosis
gmf04218  Cellular senescence
gmf04310  Wnt signaling pathway
gmf04360  Axon guidance
gmf04370  VEGF signaling pathway
gmf04380  Osteoclast differentiation
gmf04625  C-type lectin receptor signaling pathway
gmf04650  Natural killer cell mediated cytotoxicity
gmf04658  Th1 and Th2 cell differentiation
gmf04659  Th17 cell differentiation
gmf04660  T cell receptor signaling pathway
gmf04662  B cell receptor signaling pathway
gmf04720  Long-term potentiation
gmf04724  Glutamatergic synapse
gmf04728  Dopaminergic synapse
gmf04921  Oxytocin signaling pathway
gmf04922  Glucagon signaling pathway
gmf04924  Renin secretion
gmf05010  Alzheimer disease
gmf05014  Amyotrophic lateral sclerosis
gmf05020  Prion disease
gmf05022  Pathways of neurodegeneration - multiple diseases
gmf05031  Amphetamine addiction
gmf05152  Tuberculosis
gmf05163  Human cytomegalovirus infection
gmf05166  Human T-cell leukemia virus 1 infection
gmf05167  Kaposi sarcoma-associated herpesvirus infection
gmf05170  Human immunodeficiency virus 1 infection
gmf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gmf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    115858048 (PPP3CA)
   04310 Wnt signaling pathway
    115858048 (PPP3CA)
   04370 VEGF signaling pathway
    115858048 (PPP3CA)
   04020 Calcium signaling pathway
    115858048 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    115858048 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    115858048 (PPP3CA)
   04218 Cellular senescence
    115858048 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    115858048 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    115858048 (PPP3CA)
   04660 T cell receptor signaling pathway
    115858048 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    115858048 (PPP3CA)
   04659 Th17 cell differentiation
    115858048 (PPP3CA)
   04662 B cell receptor signaling pathway
    115858048 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    115858048 (PPP3CA)
   04921 Oxytocin signaling pathway
    115858048 (PPP3CA)
   04924 Renin secretion
    115858048 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    115858048 (PPP3CA)
   04728 Dopaminergic synapse
    115858048 (PPP3CA)
   04720 Long-term potentiation
    115858048 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    115858048 (PPP3CA)
   04380 Osteoclast differentiation
    115858048 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    115858048 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    115858048 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    115858048 (PPP3CA)
   05163 Human cytomegalovirus infection
    115858048 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    115858048 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    115858048 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    115858048 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    115858048 (PPP3CA)
   05020 Prion disease
    115858048 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    115858048 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    115858048 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    115858048 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:gmf01009]
    115858048 (PPP3CA)
Enzymes [BR:gmf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     115858048 (PPP3CA)
Protein phosphatases and associated proteins [BR:gmf01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     115858048 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 115858048
NCBI-ProteinID: XP_060155738
LinkDB
Position
5:121017488..121312434
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDTNLNSINKTLASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccgtttcctccaagtcaccggcttacggcaaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataatcacagagggggcttcaattcttcgacaggaaaaaaatttgctggat
attgatgcgccagtcacagtttgcggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggcggatctcctgcgaacactcgctacctcttcttaggggactatgta
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctatgtgtacacggc
ggtttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacccgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcgcaagacgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttcccaatttcatggatgttttcacttggtccctgccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagag
gaagatggatttgatggtgcaacggctgcagcccgcaaggaagtgatacggaacaagata
cgagcgatcggcaagatggccagagtgttctccgtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacgcccacgggcatgctccccagtggagtgctctctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagatcgaattaac
gagaggatgccacctcgcagagatgccatgccctctgacaccaaccttaactccatcaac
aagactctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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