Globicephala melas (long-finned pilot whale): 115865188
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Entry
115865188 CDS
T11080
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf04217
Necroptosis
gmf04380
Osteoclast differentiation
gmf04620
Toll-like receptor signaling pathway
gmf04621
NOD-like receptor signaling pathway
gmf04630
JAK-STAT signaling pathway
gmf04658
Th1 and Th2 cell differentiation
gmf04659
Th17 cell differentiation
gmf05145
Toxoplasmosis
gmf05160
Hepatitis C
gmf05161
Hepatitis B
gmf05162
Measles
gmf05164
Influenza A
gmf05165
Human papillomavirus infection
gmf05167
Kaposi sarcoma-associated herpesvirus infection
gmf05168
Herpes simplex virus 1 infection
gmf05169
Epstein-Barr virus infection
gmf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
115865188 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
115865188 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
115865188 (TYK2)
04621 NOD-like receptor signaling pathway
115865188 (TYK2)
04658 Th1 and Th2 cell differentiation
115865188 (TYK2)
04659 Th17 cell differentiation
115865188 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
115865188 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
115865188 (TYK2)
05160 Hepatitis C
115865188 (TYK2)
05171 Coronavirus disease - COVID-19
115865188 (TYK2)
05164 Influenza A
115865188 (TYK2)
05162 Measles
115865188 (TYK2)
05168 Herpes simplex virus 1 infection
115865188 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
115865188 (TYK2)
05169 Epstein-Barr virus infection
115865188 (TYK2)
05165 Human papillomavirus infection
115865188 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
115865188 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gmf01001
]
115865188 (TYK2)
Enzymes [BR:
gmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
115865188 (TYK2)
Protein kinases [BR:
gmf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
115865188 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
115865188
NCBI-ProteinID:
XP_030735508
LinkDB
All DBs
Position
3:164257653..164279975
Genome browser
AA seq
1188 aa
AA seq
DB search
MPLCQWGATTRGRKPDGDGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCLH
IAHKVGITPPCFNLFALFDVQAQVWLPPNHVLDMSRDSSLMLYFRMRFYFRNWHGMHPQE
PAVYRCGPPGSEPSSEQAEQGVQLLDPASFEYLFEQGKHEFINDVASLWELSSEEEIHHF
QNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPRSFQRQIRQHNALTQLRLRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIRDGGQA
PPDPGPESAAGPPTHEVLVSGTDGIQWRLVQAETASDGGGGGGRRMPHAGPSGKKAKAQE
VGNQPVYRPQEAPWAYFCDFQDITHVVLKERRVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLARLQPEDGLYLIHWSTSHL
HRLILTVAQRDQAPGVKGLHLRKFPIELQAGTVTLEGWDRSFPSVRELRVALQGCSLRAG
DDCFSLRHCCLPRPGEISNLIVTRGPRASSRPLNLSHLSFHQIRQEDITQLSHLGQGTRT
NVYEGLLRVGGGGPEEDKVDGGDPPMPGAGCEQELRVVLKVLDPSHHDVALAFYETASLM
SQVSHVHLVFVHGIYVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLTVAQQLASAL
SYLEDKSLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSVLSREERVERIPWTAPE
CLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQQKLPEPSCPELA
ILTSQCLTYEPAQRPSFRTILRDLTQLQPQTLPDLVDVLSVNLDSPASDPTVFHKRYLKK
IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIEILRTLYHQHI
VKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEGMAYLHAQHY
VHRDLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFY
YASDVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEK
CPCEIYCLMKNCWKAEASFRPTFQNLIPILKTVHEKYQGQAASVFSVC
NT seq
3567 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggggggccaccaccaggggcagaaagcccgatggggatggagct
cagcccatggccaccagaggaggcctgaaggtgcttctgcactgggccggccccggtggc
ggggagccctgggtcaccttcagcgaggccacactgactgccgaggaggtctgcctccac
attgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgtc
caggcccaggtctggctgcctccaaaccacgtcctggatatgtccagagactcgagcctg
atgctgtacttccgcatgaggttttatttccggaactggcatggcatgcatccccaggag
ccggctgtgtaccgctgcggtcccccagggtccgagccttcctcagaacaggccgagcag
ggggtgcaactcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
ttcataaatgacgtggcatcgctctgggagctgtcaagcgaggaggagatccaccacttt
cagaacgagagcctgggcatggcctttttgcacctctgccacctcgctctctgccatggt
gtcccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cagcggcagatccggcagcacaatgctctgacgcagctgcgcctgcggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggttgtcatggtgaagtac
ctggccacactcgagcggctggcgccccgcttcggcacagagcgcgtgcccgtgtgccac
ctggagctactggcccaggccgagggggagccctgctacatccgggatggcggacaggcc
cctcccgaccccggacccgagtctgctgcaggaccccccacccacgaggtgctggtgtcg
ggcaccgacggcatccagtggcggctggtacaggcagagactgccagtgatggtggtggt
ggtggcggcagaaggatgccccatgctggcccatctgggaagaaagccaaggcccaggag
gtgggcaatcagccagtgtacagacctcaggaggccccatgggcctacttctgcgacttc
caggacatcacccacgtggtgctgaaagaacgccgcgtcagcattcactgtcaggacaac
aagtgcctggagttgaccctgccttcccgggctgcggccctgtccttggtgtcactggtg
gatggctacttccgcctgacggccgactcgagccactacctatgccatgaggtggcgcct
ccgcgtctggtgatgagtatccaggacggtatccacggacccctgctggaaccatttgtg
ctggccaggctgcagcccgaggacggcctttacctcatccactggagcaccagccacctc
caccgccttatcctcacggtggcccagcgtgaccaggcacccggcgtgaagggcttgcac
ctacggaagttccccatcgagttgcaggctgggactgtcacgctggagggctgggaccgg
tccttccccagcgtgcgcgagctgcgggttgccctgcagggctgctccctgcgggccggc
gacgactgcttttccctgcgccactgctgcctgccacggccaggagagatctccaacctc
atcgtcacacggggacctcgggccagcagcaggccactcaacctcagccatctcagcttc
caccagatccgccaggaagacatcacccagctgtcccacttgggccagggcacgaggacc
aatgtgtatgagggcctcttgcgagtggggggcggaggccctgaagaggacaaggtggat
ggcggggacccccccatgcccggggcgggctgtgaacaggagctgcgagtggtactcaag
gtgctggatcccagtcaccatgacgtcgccctggccttctacgagacagccagcctcatg
agccaggtctcccacgtgcacctggtcttcgtgcacggcatctacgtgcacggctccgag
aatatcatggtgacggagtacgtggagcacgggcccctggacgtgtggctgcggcgggag
aggggccgcgtgcccctggcctggaagctcacagtggcccagcagctggccagcgccctc
agctacctggaagacaagagcctggttcacagcaacgtgtgtggccggaacatcctcctg
gcacggctggggctggcggagggcaccagccccttcatcaagctgagtgaccccggtgtg
ggcctgagcgtcctctccagggaggaacgggtggagcggatcccctggacagcccctgag
tgcctgtccggtggagccaacagcctaagcactgcagccgacaagtggggctttggtgcc
accctcctggagatctgcttcgatggggaggcccccctgcagggccgcagcccctctgag
aaagagcgcttctaccagaagcagcagaagctgcctgagccctcgtgcccagagttggcc
atactcaccagccagtgcctgacctatgagccagcccagcggccatccttccgcaccatc
ctgcgtgacctcactcagctgcagccccaaactcttccagatctcgttgatgtcttgtct
gtgaacctggactcaccggcgtcagatcctacggttttccacaagcgctatttgaaaaag
atcagggatctgggtgagggtcacttcggaaaggtcagcctgtactgctacgatccaact
aatgacggcactggtgagatggtggccgtgaaggccctcaaggcaggctgcggtccccag
ctccgtacaggctggaggcgagagatcgaaatcttgcgcacactctaccaccagcacatt
gtcaagtacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggag
tacgtgcccctgggcagcctccgagactacttgcctcggcacaatgtcgggctggcccag
ctgctgctcttctcccagcagatctgcgagggtatggcctacctgcacgcgcagcactac
gtgcaccgagacctggccgcacgcaacgtgctgctggacaacaacaggctggtcaagatt
ggggacttcggtctcgccaaggccgtgcccgaaggccatgagtactactgtgtgcgcgag
gatggggacagtcctgtgttctggtatgccccggagtgcctgaaggagtgtaagttctac
tatgcatccgatgtctggtcctttggggtcaccatgtatgagctgctgacctactgtgac
tccacccagagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg
acagtgctgaggctcactgagctactggaacgaggggagaggctgccacagccagagaaa
tgtccttgtgagatctattgcctcatgaagaactgctggaaagcagaggcctcattccgc
ccgaccttccagaacctcatacccatcctcaaaacggtccacgagaaataccaaggccag
gcagcctcagtgttcagtgtctgctga
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integrated database retrieval system
