Globicephala melas (long-finned pilot whale): 115865632
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Entry
115865632 CDS
T11080
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf01521
EGFR tyrosine kinase inhibitor resistance
gmf04010
MAPK signaling pathway
gmf04014
Ras signaling pathway
gmf04015
Rap1 signaling pathway
gmf04020
Calcium signaling pathway
gmf04072
Phospholipase D signaling pathway
gmf04144
Endocytosis
gmf04151
PI3K-Akt signaling pathway
gmf04510
Focal adhesion
gmf04540
Gap junction
gmf04630
JAK-STAT signaling pathway
gmf04810
Regulation of actin cytoskeleton
gmf05163
Human cytomegalovirus infection
gmf05200
Pathways in cancer
gmf05206
MicroRNAs in cancer
gmf05214
Glioma
gmf05215
Prostate cancer
gmf05218
Melanoma
gmf05230
Central carbon metabolism in cancer
gmf05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
115865632 (PDGFRA)
04014 Ras signaling pathway
115865632 (PDGFRA)
04015 Rap1 signaling pathway
115865632 (PDGFRA)
04630 JAK-STAT signaling pathway
115865632 (PDGFRA)
04020 Calcium signaling pathway
115865632 (PDGFRA)
04072 Phospholipase D signaling pathway
115865632 (PDGFRA)
04151 PI3K-Akt signaling pathway
115865632 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
115865632 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
115865632 (PDGFRA)
04540 Gap junction
115865632 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
115865632 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
115865632 (PDGFRA)
05206 MicroRNAs in cancer
115865632 (PDGFRA)
05230 Central carbon metabolism in cancer
115865632 (PDGFRA)
05231 Choline metabolism in cancer
115865632 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
115865632 (PDGFRA)
05218 Melanoma
115865632 (PDGFRA)
05215 Prostate cancer
115865632 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
115865632 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
115865632 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gmf01001
]
115865632 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
gmf04090
]
115865632 (PDGFRA)
Enzymes [BR:
gmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
115865632 (PDGFRA)
Protein kinases [BR:
gmf01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
115865632 (PDGFRA)
CD molecules [BR:
gmf04090
]
Proteins
115865632 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
Kinase-like
Motif
Other DBs
NCBI-GeneID:
115865632
NCBI-ProteinID:
XP_030736394
LinkDB
All DBs
Position
5:73513405..73558975
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHWALLVLGCLVTGPSLILCQLSLPSILPNENERIVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRDEENNSGLFVTVLEVVSASAAHTGLYTCYYNHTQLEESEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVILLSSDGVVHASYDSRQGFNG
TFTVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKAGESIVVTCAVFNN
EVVDLQWTYPGQVKGKGLTMLEETKVPSIKLVYTLMVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIRPNFSPLEAVNLHEVKHFVVDVQAYPPPRIAWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSNGGQTVRCTAEGTPLPDIEWLICKDIKKCNNETSWTILANNVSNIITEVHPRD
RSMVEGQVTFAKVEETIAVRCLAKNLLGVESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRALYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMV
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccattgggcactcctggtcttaggctgtctcgtcacagggccaagcctc
atcctctgccagctttcattaccctccatcctgcccaatgaaaacgagaggattgtgcag
ctgaattcgtccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagggacgaggagaacaacagtggcctt
tttgtgacagtgctggaagtggtcagtgcctcggcggcccacacggggctgtacacttgc
tattacaaccacacgcagttggaagaaagcgagatcgagggcagacgcatttacatctat
gtgccagacccagatgtagccttcgtacctctaggaatgacagattacttggtcatcgtg
gaggacgatgattctgccatcatcccttgtcgaacgactgatcctgagacgccagtgatt
ttactcagcagtgacggggtggtgcacgcctcctatgacagcagacaaggctttaatgga
accttcactgtcggaccctatatctgcgaggccaccgtcagggggaagaagttccagacc
atcccattcaatgtttatgctttaaaagcaacatcagaacttgatctggaaatggaagct
cttaaaactgtctataaggcaggggaatcgattgtggtcacctgcgccgtctttaacaat
gaggttgtggaccttcagtggacttaccctggacaagtgaaaggcaaaggcctcacaatg
ctggaggagaccaaggtcccgtccatcaagttggtgtacactctgatggtccctgaggcc
acggtgaaagatagtggagattacgaatgtgctgcccgccaggccaccaaggaggtcaaa
gaaatgaagaaagtcaccatctctgtgcacgagaaagggtttattgaaatcagacccaac
ttcagcccgttggaagccgtcaacctgcatgaagtcaaacattttgtggtggacgtgcag
gcctacccccctcccaggatagcctggctcaaggacaacctgactctgattgagaatctc
acggagatcaccactgacatagaaaagattcaggaaatcaggtatcgaagcaaattaaag
ttgatccgagctaaggaagaagacagcggccattatactattgtagttcaaaatgaagac
gatgtgaagagctatacttttgaactcttaactcaagttccgtcatccattctggacttg
gtcgacgaccaccatggctctaatgggggccagacagtgagatgcacagctgaaggaacc
cctcttcctgatattgagtggctgatttgcaaggatattaagaaatgtaataacgaaact
tcatggacgattttggccaacaatgtctcaaacatcatcacggaggtccacccccgagac
aggagcatggtggagggccaagtgacattcgccaaggtggaggagaccattgcagtacga
tgcctggctaagaatctcctcggggtggagagccgagagctgaagttggtggctcccact
ctgcgttctgaactcacggtggcggccgcagtcctggtgttgttggtgattgtaatcatc
tcactcattgtcctggttgtcatttggaaacagaaaccaaggtatgaaattcgttggagg
gtcattgaatcaatcagccccgatggacatgaatatatttatgtggacccgatgcaactg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctgggc
tctggtgcatttgggaaagtggttgaaggaactgcctatggattaagtcgatcccaacct
gtcatgaaggtagcagtgaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgacccacctggggccgcatttaaacattgtgaacttg
ctgggagcctgcaccaagtcaggccccatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcttgagccgccacccagagaag
cccaagaaagagctggacatttttggattgaaccctgctgacgaaagcacccgaagttac
gttattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgacactaca
cagtatgtccccatgctggaaaggaaagaggtttctaagtattcagacatccagagagcg
ctgtacgatcgcccagcctcatataagaagaaatccatgttagactcagaagtcaaaaac
ctgctttcggatgataactcagaaggccttactttgttggatttgttgagctttacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgggacctggcc
gctcgcaatgtcctcctggcgcaagggaaaatcgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattcgaactacgtgtcaaaaggcagcacctttctcccggtgaag
tggatggctcccgagagcatcttcgacaacctctacaccacactgagcgacgtctggtct
tacggcattctgctctgggagatcttttccctcggtggtacgccctaccctggcatggtg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcccgaccac
gccaccagtgaagtctacgagatcatggtgaagtgctggaacagtgagccagagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaagatccacctggacttcctgaagagtgaccatcccgccgtggcacgtatg
cgcgtggactccgacaatgcgtacattggtgtcacctacaaaaacgaggaggacaagctg
aaggactgggagggtggccttgacgagcagaggctgagcgcagacagtggctacatcatc
cctctgcctgacatcgaccctgttcctgaagaggaagacctgggcaaaaggaacagacac
agctcgcagacctctgaagagagtgccattgagacaggttccagcagttctaccttcatc
aagagagaggatgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcggacctggtggaagacagcttcctgtaa
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