Globicephala melas (long-finned pilot whale): 115865784
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Entry
115865784 CDS
T11080
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X2
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf00230
Purine metabolism
gmf00670
One carbon pool by folate
gmf01100
Metabolic pathways
gmf01523
Antifolate resistance
Module
gmf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
115865784 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
115865784 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
115865784 (GART)
Enzymes [BR:
gmf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
115865784 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
115865784 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
115865784 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
LUD_dom
DUF3104
Motif
Other DBs
NCBI-GeneID:
115865784
NCBI-ProteinID:
XP_030736656
LinkDB
All DBs
Position
4:11485201..11513000
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACCFIMSADFPALVVKASGLAAGKGVVVAKSKEEACKAVQEIMQDKAF
GEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQKTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
IGYRAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDPSTAEAVVAGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSRDLTQQILQDIQQHKEEAWVIGRVVACPEGSPRVKVKH
LIETMQINRSVLENGTLKNHVSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAYIVVV
ISNKAAVSGLNKAEGAGIPTRVINHKLYKNRAAFDTTVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGTVRLGENGKICWVKEG
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagggaacatactctggcctggaaa
cttgcacagtctaatcatgtcaaacaagtgttagttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcgaacactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggagcctgacatctgcaggagtgcggtgctttggccccacagcagaagca
gctcagttagagtccagcaagaggtttgccaaagagtttatggaccgacatggaatccca
actgcacagtggagagctttcaccaaagctgaagaagcctgctgcttcattatgagtgca
gacttccctgctttggttgtgaaggccagcggtcttgcagctgggaaaggggtagttgtc
gcaaagagcaaagaagaggcctgcaaagctgtacaggagattatgcaggataaagctttt
ggagaagctggagaaacaactgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaagactgtggcccccatgcccccagcacaggaccataagcga
ttgctggagggagatcagggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctaaaaattaaaaatactattcttcagaagacagtggat
ggcatgcagcaggagggtgtgccatacacaggtatcctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttagatggcctg
ctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaagggtgtagagataacagggtttcctgaggct
caagctttaggactagaggtgtttcaagcaggcactgccctaaaagatggcaaagtggtg
actaacgggggtagggtccttacagtaacggccatccgggaaaatctcatctcagccctt
gaagaagccaagaaaggactagctgctataaagtttgagggggccatttataggaaggac
attggctatcgtgccatagctttcctccagcagcccaggggcctgacttacaaggactct
ggggtagatattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggtttcaacgatcctcttctggcctgtggaacagacggcgttggaactaaactg
aagattgcccagcagtgccataaacatgaaaccattggtcaagatttggttgcgatgtgt
gtaaatgatattctggcacaaggagcggagcccctctttttcctcgattacttttcctgt
ggaaaacttgaccccagtacagctgaagctgttgttgctggaattgctaaagcttgtaaa
aaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtaccctcct
ggagagtatgatctagccggttttgccgttggtgcaatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggacgctgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcgaaatcttcccttcagtactcctct
ccagcacctgatggctgtggtggccaggccttaggtgatttacttctaactccaaccaga
atctacagccattcactgttacctgtcctgcgttcaggacacgttaaggcctttgcacat
attaccggtgggggattgctagaaaacatccccagagtcctacctcagaaatttggggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaagggatctgacacagcagattctgcaggatattcagcagcacaaggaagaagcc
tgggtgatcggcagagtggttgcatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaaataaatagatcagtattggagaatggcaccctgaaaaatcat
gtctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggacaggatcaaac
ctccaagctctcatagacagtactagggagccaagtagctctgcatacattgttgttgtg
atctccaacaaggcagcagtgtctggcttaaataaagcagaaggagccggaattcccacc
agggtaattaatcataaattatataaaaatcgtgcagcatttgacactacagtagaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcaccgtcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggaactgtacggcttggagaa
aacggcaagatctgttgggtcaaagagggatga
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