KEGG   Gadus morhua (Atlantic cod): 115531082
Entry
115531082         CDS       T10832                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
gmh  Gadus morhua (Atlantic cod)
Pathway
gmh04010  MAPK signaling pathway
gmh04012  ErbB signaling pathway
gmh04020  Calcium signaling pathway
gmh04510  Focal adhesion
gmh04520  Adherens junction
gmh04530  Tight junction
Brite
KEGG Orthology (KO) [BR:gmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    115531082 (erbb2)
   04012 ErbB signaling pathway
    115531082 (erbb2)
   04020 Calcium signaling pathway
    115531082 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    115531082 (erbb2)
   04520 Adherens junction
    115531082 (erbb2)
   04530 Tight junction
    115531082 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gmh01001]
    115531082 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gmh04147]
    115531082 (erbb2)
   04090 CD molecules [BR:gmh04090]
    115531082 (erbb2)
Enzymes [BR:gmh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     115531082 (erbb2)
Protein kinases [BR:gmh01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   115531082 (erbb2)
Exosome [BR:gmh04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   115531082 (erbb2)
CD molecules [BR:gmh04090]
 Proteins
  115531082 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Tcell_CD4_C Kinase-like
Other DBs
NCBI-GeneID: 115531082
NCBI-ProteinID: XP_030195969
Ensembl: ENSGMOG00000005476
LinkDB
Position
18:8814094..8836178
AA seq 1302 aa
MEARRSFLWVRLLLLGVAGALAREVCLGTDMKLDLLSSLENHYETLRLLYTGCQVVHGNL
EITHLHGVPDLSFLKGIVEVQGYVLVADVTVDLIPLDNLRVIRGSQRYGANYSLVVLNNT
KGPQGPGLRTLRMRSLTEILLGGVYMWGNPQLCFPNPQKILWRDTLDQQNTHKHQLTLQA
SAANCPRCNSVCLEKCWGETIQDCQIETHVDCTAGCLRCKGKHASDCCHKQCAAGCTGPK
DSDCLACRYFNNNGVCKEHCPAPTTYVPATYQSIPNKDKKFSFGATCIKTCPHNYLTMEA
ACTMVCPKANQEMIILNPDGSESQKCDKCEGECPKVCYGLGMGSLQGVTMVTSSNVEQFN
SCKKIFGSLAFLSQSFTGDPSSNTSGLTLDQLTPFHNLEEITGYLYIEAWPEEWSDISVF
KNLQVIRGRVLFKGVFSLVLQDLNITSVGSRSLRSVSGGLVLIHNNSRLCYTSSLPWDTL
LHPSQGPTRILSLNQDPRVCEEQGHVCHPLCKGGCWGPGPQQCVSCSAFERGLECVERCD
LYQGPTREYEKDKVCGACHSECRPINGSESCYGPGADQCRECLNFQDGEVCVERCPSGVK
EEQHTVWKYSNASGHCLPCLTNCSLSCTLMDERGCPVPTNTGPGTTIAAALGGVVLFLIL
LALLVFYLRRQQKLRRKATMRRLLQEHELVEPLTPSGALPNQAQMRILKETELKKVRVLG
SGAFGTVYKGVWAPDGESVKIPVAIKVLRENTSTKANKEILDEAYVMAGVASPYVCRLLG
ICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHRDLA
ARNVLVKNPNHVKITDFGLARLLDIDETEYQADGGKVPIKWMALESILHRKFTHQSDVWS
YGVTVWELMTFGAKPYDLIPARDIPDLLEGGERLPQPLICTIEVYMIMVKCWMIDPDSRP
RFRELVNEFSLMARDPPRYVVIQNEEQRSLTFPVDSQFFRRLLEEEGPDMKDLLDAEEYL
IPQPNMFPRTQGDGVSTAGHSRHHSYRSTDQGLDGEPPIGSACTMYSSMSTLGRGQYPTL
PLGASPSNGGWSSQYPTLARSPSSGDPCDSVFLDDATGTPASPGRYRQCDGGCHDDLMET
DGPPGAHPPPQHHHHQPHHLHHSLPRRQQGHHQSHASPEYVNQEAREVRPAVPDRPSTLP
RKTRRSEPRHLPNGLGPNGLGPGHSVENPEYLVPLGPPAAPSSPAFDNPYYLDLLAGVEG
TGVRGEGGGGVRAGERQLNGYATPTVENPEYLGLADTWTGHT
NT seq 3909 nt   +upstreamnt  +downstreamnt
atggaagcgcggagaagttttctgtgggtccgacttctgctgctcggggtggcgggcgcg
ctggccagagaagtgtgcctgggtacggacatgaagttggacctgctctccagcctggag
aaccactatgagactctgcggctgctgtacaccggctgtcaggtcgtccacggcaacctg
gagatcacccacctccacggggtgccggacctctccttcctcaagggcatcgtggaggtc
cagggttacgttctggtggccgacgtgacggtggacctgattcctctggacaacctgcgt
gtgatccgggggagccagcgctacggcgccaactactccctggtggttctgaacaacacc
aagggcccccaagggcccgggctccggaccctccgtatgcgcagcctcacagagatcctg
ctgggcggggtgtatatgtgggggaacccccagctgtgtttcccgaacccccagaaaatc
ctgtggagggacacgctggatcagcagaacacccacaaacaccagttaaccctgcaggcc
agcgccgcaaactgtccaaggtgtaattctgtgtgcctcgagaaatgctggggcgaaacc
attcaggactgtcagattgaaacccatgtcgattgtaccgcagggtgtctgcgctgtaag
ggtaagcatgccagtgactgctgccacaagcagtgtgctgctggatgcaccgggcccaag
gactctgactgcctggcgtgtcgttactttaacaacaacggcgtgtgtaaggagcactgc
ccggccccgaccacctacgtgccggccacctaccagtccatacccaacaaggacaagaag
ttcagcttcggcgccacctgcatcaagacctgcccccataactacctgaccatggaggcg
gcgtgcaccatggtgtgtcccaaggccaaccaggagatgatcatcctcaaccctgacggc
tcggagagtcagaagtgcgacaagtgcgagggagaatgtcccaaagtgtgctatggcctg
gggatgggtagcctccagggcgttaccatggtaacatcctcaaatgtggagcaattcaac
agctgcaagaagatcttcggaagcctcgccttcctctcccagagctttacaggagacccg
agcagcaacacgtcaggtctgaccctggaccagctcacaccgttccacaacctagaggag
atcactggctacctgtacattgaggcgtggccggaggaatggagcgacatcagcgtgttt
aaaaacctgcaggtcatcaggggaagggtgctcttcaagggggtgttctccctggttctc
caggacctcaacatcacctcggtgggctcgcggtctctccgtagcgtgagcgggggtctg
gttctcatccacaacaacagccggctgtgctacacgtcctccctgccctgggacacgctg
ctgcaccccagccaggggcccacccgcatcctcagcctcaaccaggacccccgtgtctgt
gaggagcagggacacgtgtgccaccccctctgtaaggggggctgctggggcccggggccc
cagcagtgtgtctcctgcagcgccttcgagaggggcctcgagtgtgtggagcggtgtgac
ctctaccaggggcctacgcgggagtacgaaaaggataaggtgtgcggtgcctgtcactca
gaatgtcgaccaatcaacggctccgagtcatgctatggcccgggtgcggaccagtgcagg
gagtgtttgaacttccaggacggggaggtgtgtgtggagcgctgccccagcggggtgaag
gaggagcagcacaccgtctggaagtacagcaacgcctcggggcactgcctgccctgtctg
accaactgcagcctctcgtgtaccctgatggacgagcgcgggtgtcctgtccccaccaac
accggtccagggacgaccatcgcggcggccctgggcggggtggtcctcttcctcatcctg
ctggcgctgctggtcttctaccttcgacgccagcagaagctccgcaggaaggccaccatg
cggcgccttctgcaggagcacgagcttgtggagcccctgactcccagcggcgcgctgccc
aaccaggcccagatgcgcatccttaaagagacggagctcaagaaggtccgagtgctcggg
tctggggcgttcggcactgtgtacaagggtgtgtgggctccagacggcgagagtgtgaag
atccccgtggccatcaaggtgttgagggagaacacgtccaccaaggccaacaaggagatc
ttggacgaggcgtatgtgatggcgggcgtggccagcccctacgtgtgtcgtctgctgggg
atctgcctgacctccacggtgcagctggtcacccagctcatgccctacggctgcctgctg
gactacgtccgcgagaacaaggaccgcatcggctcccagttcctcctcaactggtgtgtc
cagatcgccaagggtatgagctaccttgaggaggtgcgtctggttcacagagacctggca
gccaggaatgttctggtgaagaaccccaaccatgtgaagatcacagactttggcctcgcc
agactgctggacatcgatgagacagagtaccaggcagacggagggaaggtgccaatcaaa
tggatggccctggagtcaatccttcacaggaagttcacccaccagagtgacgtgtggagc
tatggcgtcacggtgtgggagctgatgacgttcggggccaagccctacgacctcatccca
gcgcgggacatcccggacctgctggaggggggcgagcggctcccccagcccctcatctgc
accatcgaggtctacatgatcatggtcaaatgttggatgatcgacccagacagcaggccg
cggttccgagagctggtcaacgagttcagcctcatggctcgcgacccgccccgctatgtg
gtcatacagaacgaggaacagaggagcctcaccttcccggtggacagccagttcttccgg
aggctgctggaggaggagggcccggacatgaaggacctcctggacgcggaggagtacctg
atcccccagcccaacatgttcccccgcacccagggggacggggtgtccaccgccggacac
tccaggcaccactcctaccggagtacagaccagggcctggacggggagccccctattggc
agcgcctgcaccatgtactcctccatgagtaccctgggtcggggccagtaccccaccctg
ccactaggggccagcccctccaacggcggctggagctcccagtaccccacgctggcgcgc
agcccctcctccggagacccctgtgactccgtcttcctggacgacgccacggggacgccg
gccagtcccgggcgctaccgtcaatgcgacggcggctgccacgacgacctgatggagacg
gacggcccgcccggcgcccatcccccacctcagcatcaccatcaccaacctcatcatctc
catcactcgctgccccggcggcaacaggggcaccaccagagccacgccagcccagagtac
gtcaaccaggaggcccgtgaggtgcggccggcggtcccggaccggcccagcacgctgccc
cgtaagacccgccgctcggagccccgccacctgcccaacggcctgggccccaacggcctg
ggccccgggcacagcgtggagaaccccgagtacctggtccccctggggccccccgcggcc
cccagctcccccgccttcgacaacccctactacctggaccttctggccggagtagagggg
actggggtcaggggtgagggggggggcggggtcagggcgggggagaggcagctgaacggc
tacgccacgcccacagtggagaaccctgagtacctgggcctggccgacacctggaccgga
cacacctga

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