Girardinichthys multiradiatus (darkedged splitfin): 124859309
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Entry
124859309 CDS
T08099
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
gmu
Girardinichthys multiradiatus (darkedged splitfin)
Pathway
gmu00270
Cysteine and methionine metabolism
gmu00480
Glutathione metabolism
gmu01100
Metabolic pathways
gmu01240
Biosynthesis of cofactors
gmu04216
Ferroptosis
Module
gmu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
gmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
124859309 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
124859309 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
124859309 (gclc)
Enzymes [BR:
gmu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
124859309 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
124859309
NCBI-ProteinID:
XP_047207984
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Position
22:complement(27793208..27810091)
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AA seq
630 aa
AA seq
DB search
MGLLSQGSPLNWEEARKYADHIRKHGIIQFLNIYNKVKDRQRDVLKWGDEVEYMLVELDD
NDEKVRLVLNGGDVLETLQEQGEKINPNHPTLWRPEYASYMIEGTPGQPYGGTMSEFNTV
EGNMRKRRLEASSVLKKNEMLCTITSFPRLGCPGFTKPECLPTPVEKGVSKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIYKDKCTPSPFVEHFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLKPLKNSKYRIFKSRYDSIDSYLSCCGERYNDIDLTIDEEINRQLL
GAGIDKLLAQHVAHLFIRDPLSVFQEKLHMDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRNAV
QEGMFYFRKDMFKGCNPRLDGAASAQNGVETEGGNEDYTLMSIDTIINGKEGVFQGLIPI
LNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVAKWMREFVAKHPQYKQDSVITDKI
SYDLFKKFDRIGKGEEQCPELFGNPVNRVK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atggggttgctgtcacaaggatctccactgaactgggaagaagcaaggaagtatgctgac
catatcagaaagcacggcattattcagttcctcaatatctacaacaaggtcaaggatcgc
cagagagatgtgttgaagtggggtgacgaggtggagtacatgctggtggagctggacgac
aatgatgagaaggttcgactggtgttgaatggtggagatgttctggaaactctccaagaa
cagggagaaaaaataaatccgaatcatccaacactttggagaccagagtatgcgagctac
atgattgagggaactcctgggcagccatacgggggaacgatgtcagagttcaacaccgtg
gagggcaacatgaggaagagacgtctagaggcttcgtctgtcctaaaaaagaatgagatg
ctctgcaccattacctcctttccaaggttaggttgtccaggtttcaccaaaccagagtgc
ctacccactcctgttgaaaagggagtgtcaaagtctctgtttttcccagatgaggccatc
aacaaacacccaagattcagcactctgaccagaaacatacgtcatcgaagaggagagaaa
gttgtgataaatgtgccgatctacaaagataagtgcacgccatctccatttgtggagcac
tttcctgaggacgatggcgaagcagcaagagcagcccttcctgaccatatctacatggac
gccatgggcttcggcatgggcaactgctgtctgcaggtgacattccaagcttgcagcatt
gatgaggcaaggtatctttatgaccaactagcaacattctgccccattgtgatggcgctg
agtgctgcctcacccttttacagagggtatgtttctgatattgattgtcgctggggagtt
atctcagcctcagtggatgacaggacccaagaggaacgtggactaaagccactgaaaaac
agtaagtacaggattttcaagtccaggtatgactcaattgacagctacctgtcttgctgt
ggggagaggtacaacgatattgatttgacaatagatgaggagatcaacaggcagctgctc
ggtgcagggattgacaagcttctggctcaacacgtagctcacctcttcatacgagaccca
ctctccgtctttcaggagaagttacatatggacgatgaaaacgagtcggatcactttgag
aatcttcagtcgaccaactggcagacgatgcggtttaagcctccacctccgaactccgac
atcggctggagagttgagttccgtcccatggaggtgcaactgactgactttgaaaatgct
gcttatgttgtttttgttgtcctgctcactagagtgatcctatcctacaagctggatttc
ttaattcccttatcaaaggtcgatgagaacatgaagatggcgcagaagagaaacgcagtg
caggagggcatgttttatttccggaaagacatgtttaaaggctgtaacccgcgcttggat
ggtgctgcttctgcacagaatggcgtagagaccgagggcggtaacgaggattacaccctc
atgagcatcgacacgatcatcaacggaaaggagggagtatttcaagggcttatcccaatc
cttaactcctacctggaaaacatggaagttgacgttgacaccaggtgcactattttgaat
tatctgaagctcatcaagaaacgtgcctcaggggaactgatgaccgtggccaagtggatg
agggaatttgttgcaaagcaccctcagtacaagcaggacagtgtcattactgacaagatc
agctatgacctgtttaaaaagttcgacaggattggaaaaggcgaagagcagtgccccgag
ctttttggtaacccagtgaaccgggtgaaatga
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