KEGG   Girardinichthys multiradiatus (darkedged splitfin): 124869445
Entry
124869445         CDS       T08099                                 
Symbol
egfra
Name
(RefSeq) epidermal growth factor receptor
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
gmu  Girardinichthys multiradiatus (darkedged splitfin)
Pathway
gmu03272  Virion - Hepatitis viruses
gmu04010  MAPK signaling pathway
gmu04012  ErbB signaling pathway
gmu04020  Calcium signaling pathway
gmu04068  FoxO signaling pathway
gmu04144  Endocytosis
gmu04510  Focal adhesion
gmu04518  Integrin signaling
gmu04519  Cadherin signaling
gmu04520  Adherens junction
gmu04540  Gap junction
gmu04810  Regulation of actin cytoskeleton
gmu04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:gmu00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    124869445 (egfra)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124869445 (egfra)
   04012 ErbB signaling pathway
    124869445 (egfra)
   04068 FoxO signaling pathway
    124869445 (egfra)
   04020 Calcium signaling pathway
    124869445 (egfra)
  09133 Signaling molecules and interaction
   04518 Integrin signaling
    124869445 (egfra)
   04519 Cadherin signaling
    124869445 (egfra)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    124869445 (egfra)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124869445 (egfra)
   04520 Adherens junction
    124869445 (egfra)
   04540 Gap junction
    124869445 (egfra)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    124869445 (egfra)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    124869445 (egfra)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gmu01001]
    124869445 (egfra)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gmu04147]
    124869445 (egfra)
Enzymes [BR:gmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     124869445 (egfra)
Protein kinases [BR:gmu01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   124869445 (egfra)
Exosome [BR:gmu04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   124869445 (egfra)
  Exosomal proteins of pancreatic cancer cells
   124869445 (egfra)
  Exosomal proteins of bladder cancer cells
   124869445 (egfra)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 124869445
NCBI-ProteinID: XP_047223242
LinkDB
Position
6:complement(29420315..29483076)
AA seq 1209 aa
MTPWSPHPSFENTMAARFLLWISLTSLLCLGSRVLAEKKVCQGFTNRLNLLGSKEDHYLN
MLKTYSNCTVVLENLEITYVEEHRDLSFLRSIEEVSGYVLIALNTAPRIPLENLRIIRGH
SLYEGKFALSVLANIDKDTGQGTTELLLTSLTEILKGGVKFGNNKLCNVESIQWFDIVNA
ETKPSMILPVAGNNPTCQKCHSSCFNGSCWAPGLENCQTLTKLNCAQQCSKRCKGPSPSD
CCNEHCAAGCTGPRPTDCLACRDFQDDGVCKDSCPGLVRYDPNLHQLVPNPQGKYNFGAT
CVKSCPHNYVVTDHGACVRSCSGNTYEVDEGGIRKCAKCDGLCPKVCNGLGAGELTHTLS
INATNIGSFKNCTKISGDITIIHTSIHGDPYTNTPKMEPAQLDVFKTVKEITGHLWIQTW
PESMSSLSPFENLEIIRGRTKRGIRTVVVTKLNIDYLGLRSLKEISDGEVVIIKNQNLCY
TEQSHWNRFFKSKAQTATVSENTNATTCALRKKTCDRKCTVDGCWGPGPDMCFACRDYSR
GESCVDSCNILEGNPREAVMNKTCMECDPECLRMNGTATCRAPGPGNCTKCANYQDGLFC
VSRCPQGVPGEDDTLVWKYADEKRVCQLCHKNCTKGCTGPGPEGCQDERPSGLSMIAAGV
VGGLLVVLITGISVFVLLRRRHIKRKRTMRRLLQERELVEPLTPSGQAPNQALLRILKEP
EFKKIKVLGSGAFGTVYKGLWVPEGEDVKIPVAIKVLREATSPKANQEILDEAYVMASVE
HPHVCRLLGICLTSTVQLITQLMPYGCLLDYVKENKDNIGSQHLLNWCVQIAKGMNYLEE
RHLVHRDLAARNVLVKTPHHVKITDFGLAKLLNADEKEYHADGGKVPIKWMALESILNRT
YTHQSDVWSYGVTVWELMTFGTKPYDGIPASEIAGILEKGERLPQPPICTIDVYMIMVKC
WMIDAESRPHFRELIAEFTKMARDPPRYLVIQGDDRMHLPSPTDTKFYRSLISGEGLEDG
VDADEYLVPQHGFFSSPSTSYTPLLHSTSLNSSIGTCINRNGLMNGVPSRDGSIVLRYIP
DPTDKFLDEAFLPAPDYVNQNGVSNVINPIYQHSCPPRTLLPTISSDDTESEYLNYFKNG
SNGPEYLNELPASNTLPFNSNNLAHSGQNYRPQNSIDNPDYQQDFTPTFKTHANGHIPAA
ENVEYLGPD
NT seq 3630 nt   +upstreamnt  +downstreamnt
atgacaccgtggtctcctcacccgagcttcgaaaacacgatggcagcccgttttctgctt
tggatcagcctcacctctctgctctgcctgggctcccgtgttctggcggaaaagaaagta
tgccaaggtttcaccaatcgcttgaatcttctgggctctaaagaggaccactatctgaac
atgctgaagacctacagcaattgtaccgttgtcctggagaacttggagatcacttacgtg
gaggagcaccgtgacctgtccttcctcaggtcaattgaagaagtaagtggctatgttctg
attgccctcaacacagcccccaggattcctctggagaacctgcgcatcattcgaggtcac
tccctctatgaaggaaagtttgcactttcagtgcttgccaatattgataaagatacaggt
cagggtaccaccgagcttcttctgaccagtctgacagaaattctcaaaggaggtgtaaag
tttgggaacaacaaactttgtaacgtggaatcgatacaatggtttgatattgtcaatgct
gaaacaaaacctagcatgatactcccagtggcgggaaacaacccaacttgtcaaaaatgc
cactcaagctgtttcaatggttcatgttgggcacctggtctagaaaactgtcagacctta
accaagctgaactgtgcacagcagtgctccaagaggtgcaaaggaccttcaccaagcgac
tgttgcaatgagcattgtgcagcaggatgcacagggcccagacccactgactgtctggcc
tgtcgggacttccaggatgatggggtgtgtaaagactcctgcccgggcctcgtgcgctat
gatcccaacctgcaccagctggtccctaatccccaaggaaagtacaactttggggccacc
tgcgtgaaaagctgcccacataattatgttgtgactgatcatggtgcgtgtgtgcggtca
tgcagcggtaacacctatgaagtggacgagggaggaatcaggaagtgtgcaaagtgcgac
ggactgtgcccaaaagtgtgtaatggacttggagcaggagagctgactcacaccttgtct
atcaatgctaccaacattggttcctttaagaactgcaccaaaatcagtggcgacattacc
atcattcacacatcaattcatggggatccgtataccaatacaccaaagatggagccagcc
caactggatgtatttaaaacagttaaggaaattacgggacatctgtggattcaaacatgg
ccagagagcatgagctcactcagtccttttgagaatctagaaatcattcgaggaagaaca
aaacgtggtatccgcactgtggttgtgacgaagctcaatatcgactacctcggccttcgg
tcactaaaagagatcagcgatggagaggttgtcatcatcaaaaatcagaacctctgctac
acagagcagagccactggaacaggttcttcaaatcaaaagcccagactgcaacagtcagt
gaaaacacaaatgctaccacttgtgccctgaggaaaaagacgtgtgacaggaagtgcaca
gtggatggctgctggggcccaggcccggacatgtgttttgcctgccgtgactacagccgt
ggcgagagctgtgttgactcctgcaacatcctggagggaaatccacgggaggcagtcatg
aataaaacctgcatggagtgtgaccccgagtgtctacgcatgaacgggactgcaacctgc
cgggcgccgggtcccggaaactgtacaaagtgtgccaactatcaggatgggctgttctgt
gtgtctcgttgtccccaaggtgtgccaggagaggatgacaccctggtgtggaaatacgca
gatgagaaaagagtgtgccaactgtgccacaagaactgcacaaaggggtgcacgggacca
ggtcctgaaggttgccaagatgaaaggccctcaggtctctccatgattgcagccggggtt
gttggtggactgctggttgttctgatcaccggcatctctgtcttcgtgctgctccgccgc
cgccacatcaagaggaagaggacgatgcgcagactgcttcaagagagggagctggttgaa
cctctcactccgagtggacaggcaccaaaccaagctctgctgcggatactgaaggaacca
gagtttaagaaaattaaagtgctgggatcaggagcttttggtacagtttacaagggtctt
tgggtcccagaaggagaggatgtgaagattccagtggctatcaaggttctaagagaggcc
acatcacccaaagcaaaccaagagatcttggatgaagcttatgtgatggccagcgtggaa
cacccgcatgtgtgccgcctcctgggtatctgcctcacttcaacggtgcagctcataacg
cagctgatgccttacggctgcctgctggactacgtcaaagaaaacaaggataatatcggc
tcccagcacctgcttaactggtgtgttcagatagccaagggtatgaactaccttgaggag
cgccacttagttcaccgggacttggcagccagaaacgtcctggtcaagactcctcatcat
gtgaagatcactgactttggcctggccaaactcctcaacgcagatgagaaagaataccat
gcagatggaggaaaggtaccaataaaatggatggctcttgaatcaatcctaaatagaact
tacactcaccagagtgatgtctggagctacggtgtaacagtctgggaactgatgacgttc
gggaccaaaccatatgatgggattccagccagtgaaatagccggaatcctggagaaagga
gagcgcctgcctcagccaccaatctgtaccatagacgtctacatgatcatggtgaaatgt
tggatgattgatgcagagagccggcctcatttccgggaactaatagccgagttcacaaag
atggctcgagatccaccccgctatcttgtcatccagggtgacgaccgcatgcacctgcca
agtccaacagacaccaaattctaccgcagcctgatcagcggggagggcctggaggatggt
gtagatgcagatgaatacttggtgccacagcacggcttcttcagcagcccaagcacctcc
tacaccccgctgcttcattccacaagcctcaacagcagcataggaacatgcatcaacaga
aatggcttaatgaacggagtcccaagcagagacggaagcatagttctccgatatattcct
gacccaacagacaaattcctggacgaggccttcctgccggctccagactacgtgaaccag
aacggagtttccaatgtgattaatcccatctaccaacattcttgtccacctcgcaccctt
cttccaaccatctcctcagatgacacggagtcagagtacctgaactactttaagaacggg
tccaatggacccgaatacctcaatgagctcccagcctcaaacaccctgcccttcaactcc
aacaacctggcccacagcggtcagaactacaggcctcagaacagcatagacaacccagac
taccaacaagatttcacccccaccttcaagacacatgcaaacgggcacataccggcagca
gagaacgtggagtacctgggtccggactga

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