Girardinichthys multiradiatus (darkedged splitfin): 124878490
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Entry
124878490 CDS
T08099
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
gmu
Girardinichthys multiradiatus (darkedged splitfin)
Brite
KEGG Orthology (KO) [BR:
gmu00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gmu01001
]
124878490 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gmu04131
]
124878490 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gmu04147
]
124878490 (lrrk2)
Enzymes [BR:
gmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
124878490 (lrrk2)
Protein kinases [BR:
gmu01001
]
Serine/threonine kinases: TKL group
LRRK family
124878490 (lrrk2)
Membrane trafficking [BR:
gmu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
124878490 (lrrk2)
Exosome [BR:
gmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
124878490 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_14
LRR_13
Ank_2
Beta-prop_EML_2
TniB
LRR_9
AAA_22
G-alpha
Arf
WDR55
LRR_NXF1-5
BLTP3A_B
AAA_16
Beta-prop_BBS7
SRPRB
PduV-EutP
Ank_4
Motif
Other DBs
NCBI-GeneID:
124878490
NCBI-ProteinID:
XP_047238413
LinkDB
All DBs
Position
2:2770013..2836769
Genome browser
AA seq
2537 aa
AA seq
DB search
MDNREELAERLKKLLVRLKTPQEDRQLSTLIQILKDLLSLARTEHAAELFEDKDVHLPLT
VVLSSNMSSKGVQQVGLSLLCQLFEICPNTLEELTRPLQASREWEILGVHQQILKALSQY
ITDPQVTMFGLRALAVLLRSDAVPLLMLDEEEDVFSLVVVAMKTFPTNKEVQFQGCMALQ
LLLGQVTDDHLVEFVENQDHVVVLSALQMFSDCPKLLIQAMKMLLPLARTGSNVEVLMSG
GTRCYSIVIAAMDAFPEVEELQETACLLFRRFTSESFYSILVTNGVQRVSLRACQTFPDN
AALQAAALSCLADLTATIVQNKAVAEQGLEEGEEEEERGMEGVEDMGLDWMEDCCTALEL
HAADPAVQEAASWAIHNLLLHGVQVKPSDEEQGGRTPVHRQLMAAMLLHSTSPSVFIAAT
SAIATLITNNSKMSSLLLTGGLHVNLVEMMKRHSSSAEVSISACKLLKLLFHGRTASLDE
LNMAMSQILNVMKVHNFQSEVQLAALEASLIFLCPDRSLRENGASVSDPDMADVSLRVLK
NQCVVEGAHTLYLEVLNRFISRPTLQQCGLKVLSSLADCSGAVDLLCQQGAIDTVLHTLQ
MFPKEREIHYWGLTLLSYLVTKKKLSRMVVPVLASVVVASLSQYRQDSEMVLKCFQVAYR
MLDACSGAGAELQREDFDRQIFQHLRQESRQSVSPLRRSVCLALSKMCCDSELHYSMLEK
ACMDGDTMMAECLIELGADVNTKAKTESLIYQVCEKGGPLELVELLLSRDTPEQQLRRAL
AVSVKRGDGPVVILLLGRLGLDLNNGALCLGGFRLGRLDAAWLSPLLAERNRAYSLRCNG
KGVSLARYIQSLQRSKGVGGFSRPMSDQCLTSGYISDESDDSSFSGVSMDDSLFLNDDIE
SDGSDSVSALSPKSKNNSAEELRGDSLRRKQGRHRHASAESPKAENENGEPTHRRYGRTH
SKSVLGFADNSAALPKEKERIRLLDLSGNELDSLSCFLDDAFVQQQLWHVLRLDLSSNSL
LEFPSAICQSLRSLTRLDLQGNQLHSLPDDLLALPSLSMLNVSRNLIGPVLSFDPAVTCP
SLRQLNMSFNKVSTFPYELGRTMEKLEELFMEGNSLTDLSSALYLPEIKLLDVSKNNVEK
VSPDFLTSCPKLETFNASMNKICSLSQLPAKVTTLKLANNNFTHVPEAILNLPILRSLDM
RTNNIDVLPGPGCWASHKIRELMFSQNCIKELDLSGPIYRWAGLEKLHLSDNKLSEIPPQ
IGMIEGLTSLDVSRNSSLRLFPEEMGKLVRLWDLPLDGLRLELDLKLIGNKTKDIVRFLQ
QRLKKAVPYHRMKLIVVGNTSCGKTTLVRQLMKLKRSQLTSKQSAVDVFDWIIKERDKKK
MLLNVWDFSGGEELTGCHPLFLTSRALYLVVYNLSKGASQVDALKPWLFNIKAVAPLSPV
ILVGTHTDLSEELQLQSCLNKIQQELLNHQGFPTIRDYHMVSLCEDSDSIVKLRKAIIKE
VTSFKIQGQHVMGQLVPDSYVELERRILLERIRVPPEFPVLRYNRLLQLIEESQLQLEEA
ELPHAIHFLSEVGILLHFDDPALQLPELYFIDPQWLCNILSQKLTLKSCGLLEQPKGVVQ
RSVVERFLLETKFFPKSHMVQFFKLLEKFQIALPFGEDQLLVPSSLSKQRPVIELPHCEN
SEVIVRLYEMPYFPMDFWSRQISRLLEVSSYLLCGREKVLRPNRIYWRRGIYLNWSPEAY
CLMEATSDEQSPSSFVRITVPSSQKGRVLLGQVVDHVDSVLEEWFPGLLNTDMHGNGEAL
LKKWVLYSFEDGQELRKILLDDLYRHFDHDFLLVNPENPRYRLPISQIAPDLVLSDQPAG
TLLDSEELKVDLSTENRLGNGGFGTVYRGVYKNEEVAVKVFNKHASDLYVHRLLRQELAV
LGRLRHPSLVGLLAGSSAPQVLVMELALRGSLDSLFDHENGSLNRKLQHRIALHVADGLR
YLHFAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEV
ARGNVIYNQQADVFSFGLLLYDLLTSGERISDGMKFPSEFDEIAVQGKLPDPVKQYGCSP
WPNFQALMMDCLRESPQDRPTSAQLFDRLNSGEMLCLMSEVKVSSMFSAQCITVSCRSSS
GQRTSSQTAWLGGGSSSRKRGFITAVDLQTNTVTSKEVDTSPVLCLATVRIPNDESDWLV
AGTQSGSLLVISTQDVSTWHHLQSVTDAVTSLYFHLHPQHIQRTNYLLVGTADGVLSVYE
ESVLMQENGQPVKTLTVGNISTPLMCLGQSTHSLDNKSVWAGCGTKILSFSVDYDVCKSI
DTRPHPIFHQQRPLSSEAFVSRMVVDKHVYLSKAGTPTVEVWDKRSERMVDCINCSQIIR
QESGCRRGSRVELPSEASPSWATVKALMMQNTAALWIGTRGGYLLLLELSNHQTLQVMAP
SCNSICSISSAFKQSMNWKNAVLVLGRRLPRDKNQDDEETLLMVWNSMLPLEVKDLKKHC
EKRARAAARMREQLHHT
NT seq
7614 nt
NT seq
+upstream
nt +downstream
nt
atggataacagagaagaattagcagaacggctgaagaaactgctggtgcggctgaaaacc
ccacaggaggacaggcagctgtccacactgattcaaatcctcaaggatctgctgtctctg
gcgcgcacggaacatgcggctgagctgtttgaagacaaagatgttcatctacccctcaca
gtggtactttcatctaatatgagcagcaaaggagtccagcaggtgggcttatcgctactg
tgccagctctttgaaatatgcccaaacaccctggaggagctcactagacctctgcaggcc
agccgggagtgggagatactgggagtgcaccagcagatcctgaaggccctatctcaatat
attacagaccctcaggtgaccatgtttggactcagagccctggcagtactgctcagatca
gatgcagttcctctgctgatgctggacgaagaagaggatgtgtttagcctggttgtggtg
gcgatgaagacatttcctaccaataaggaagtgcagttccaaggttgtatggctctgcag
ctgctgctgggccaagtaactgatgaccatctggttgagtttgtggaaaaccaggaccat
gttgtggttctttcagctctgcagatgttctctgactgccccaagcttctcatccaggcc
atgaaaatgttactccctttagctcgaacaggcagtaacgtggaggtgttgatgtctgga
ggcactcggtgttacagcatagtcatcgctgccatggatgctttccctgaggtggaggag
ctgcaggagacagcctgcctgctgttcagaaggttcacctcagagagtttctacagcatc
ctggtgaccaacggcgtccagagggtctctctgagagcctgtcagaccttccctgacaat
gctgccctgcaagctgctgccctctcctgcctggctgaccttactgcaaccattgtgcag
aacaaagcggtggctgagcagggtctggaggaaggagaggaggaagaggagagaggcatg
gagggggtggaggacatgggcctggactggatggaggactgctgtacagcgctggagctc
catgcagctgatccggctgttcaggaagctgcgagctgggccattcataacctgctacta
cacggagtccaagtaaagccttcagatgaagagcagggtggcaggactcctgttcacaga
caattaatggctgccatgctgctccactccacctctcccagtgtgttcattgcagctacc
agtgccatcgccacactcattaccaacaacagtaaaatgagctccttgttgctgactggt
ggcctccatgttaacctggtggagatgatgaagagacattcaagctcagcagaagtctcc
atcagtgcctgcaagctcttaaagctgttgttccatggaaggactgccagcctggatgag
ctgaacatggccatgagccagatcctcaacgtcatgaaggtccacaacttccagtcggag
gttcagcttgcagcactggaggccagtctgatcttcctttgcccagacaggagcttaagg
gagaacggtgcgtccgtctcagatcctgacatggctgatgtgtcgctgagagtcctgaag
aaccagtgtgtggtagaaggggctcacacactctacctggaggtcctcaacaggtttatt
agcaggcccaccctacagcagtgcggcctgaaggtgctgtcatccctggcagactgctca
ggtgcagtggacctattgtgccagcagggggcgatagacacagtgcttcatacactacag
atgtttccgaaggaacgagagatacactactggggtctgacccttcttagctacctcgtg
acgaagaagaagctgtcgaggatggttgtgccagtcctggcctctgttgtcgtcgcctcc
ctcagtcagtacagacaagattctgagatggtgttgaagtgttttcaggtggcgtatagg
atgttggacgcctgctcgggggcaggagctgaactgcaaagagaagacttcgacaggcag
atcttccagcacctcagacaggagagcaggcagagtgtcagcccactgcggaggtcggtg
tgtctggctttgtcaaagatgtgttgcgactccgagctacactacagcatgctggaaaag
gcctgcatggatggcgacacgatgatggcagagtgcctcattgagctgggggccgatgtc
aacacgaaggcaaaaacagagtctctcatttatcaggtatgtgagaaaggtggtcctctg
gagctggtggagctcctgctgagcagagacactcctgagcagcagctccgcagggctctg
gctgtaagtgtgaagaggggagatgggcccgtagttatcctgctgctcggccggcttggt
ttggacctcaacaacggcgccctctgtcttggaggcttcagactgggccgactggatgct
gcctggctgagccctctgctggctgaacgaaacagagcatacagtctgcgatgcaacggt
aaaggtgtaagcttggcgaggtacattcagtctctgcagaggtcaaagggcgtcggtggt
ttttctagaccaatgtcagaccagtgtctgacttctggctacatttctgatgaaagcgat
gactccagcttcagtggcgtgtctatggatgacagcttgtttctaaatgacgacatagag
agtgatggaagtgattcagtgtcggctctgtctccaaagtcaaaaaacaactcagcagag
gagctgaggggagactccttgagaaggaagcagggacgtcacagacacgccagcgcagag
agtcctaaagctgaaaatgaaaacggtgaacccacacacagaagatatggacggactcac
tcgaagtcagtgctgggatttgctgacaactctgctgctctgcccaaggaaaaggagcgg
atccgtctgttggatttgtcagggaatgagttggactctctgtcttgtttcctggatgat
gcttttgtccagcagcagctatggcatgtccttcgtctggacctgagcagcaacagtctg
ctggagttcccctctgccatctgccagagtttgagaagtctgacccgactggacctgcag
ggtaaccagcttcattcgttgccagatgacctgctggctctgccctcactgagcatgctc
aatgtctctcgtaacttaatcggccctgtgttgagcttcgacccggcggtcacatgcccg
tcactcaggcagctcaatatgtcattcaataaagtcagcacgttcccctatgagctgggc
cggaccatggaaaagctggaggagctgttcatggaaggtaacagtctgactgacctgagc
tcagctctctatctcccagagatcaagctgctggatgtgagcaagaataacgtggagaag
gtttccccagactttctgaccagctgtcccaaactggaaacctttaatgcttcaatgaat
aaaatctgttccctttcacagctgccagccaaggtgacaacattgaaactggctaacaac
aacttcacccacgttcctgaggccatactgaatctaccaatcttacggtcattggacatg
aggaccaacaacattgatgttttacctggcccggggtgctgggcgtcccacaaaatcagg
gagctaatgttcagtcagaactgcatcaaagagttggatctgagtggaccaatctacaga
tgggccggactggagaagctccatctaagtgacaacaagcttagtgagatcccaccacaa
attgggatgatagaaggcctgacctctctggatgtgagtcgtaattctagcctgaggctc
ttcccggaagaaatgggaaagctggtcagactgtgggacctgccactggatggccttcga
cttgagctggatctgaaacttattggcaacaagaccaaagacatagtcaggttcctgcag
cagcgcctgaagaaggcagtgccataccaccgcatgaagctcattgtggtgggcaacact
agctgtggaaagaccaccctcgtcaggcagctgatgaagctgaagcgctcccagttgacc
tcaaaacagagtgctgttgacgtttttgactggatcatcaaggaacgggacaagaagaaa
atgttgttgaatgtctgggacttctcaggtggagaggagctcactggctgtcaccctctc
tttcttacatccagagctctctacctggttgtgtacaacctcagtaaaggagccagtcag
gtggatgctctgaaaccctggctcttcaacattaaagcagtggctccgctgtctccagtc
atccttgttggaacccacactgacttgagtgaagagttgcagctccagtcctgcttaaat
aaaatccaacaagagctgctgaaccatcaaggtttccccaccattagagattatcacatg
gtctcgctctgtgaggactcagactccattgtcaaactccgcaaggcaatcatcaaagag
gtcaccagcttcaagattcagggccagcatgttatgggtcaactggtgccagatagctac
gtggagctggaacgtagaattctcctggaaaggatcagggtcccaccagagtttcctgtc
ctcagatacaataggcttctgcagcttatcgaggagagccagcttcagctggaggaagcc
gaactgcctcacgccatccatttcctcagtgaagtcggcattttattacactttgatgac
cctgcactccaacttccggaactttattttatcgacccacagtggttgtgtaacattctg
tctcagaaactgacattgaagagctgtggtctcttggagcaaccaaaaggagtggttcag
cgttctgttgtggaaaggtttctgttagagaccaaatttttcccaaagagccatatggtc
cagttctttaagcttctggagaagtttcagattgcccttccttttggtgaggaccagcta
ttggtacccagcagtttgtccaaacaaagaccggttatagaactaccacactgtgagaac
tctgaggtgattgtacgtctctatgagatgccgtacttccccatggatttctggtctcgg
cagatcagtcgccttttagaagtctcctcgtatttgctctgtggaagagaaaaggtgctt
cgacccaaccgtatttactggaggcgaggcatttacctaaactggtcccctgaagcatac
tgtctgatggaggcaacttcagatgagcagagtccctccagctttgtcaggataactgtg
ccctcatctcaaaaaggccgagtgttactgggccaagtggtggaccatgttgactctgta
ctggaggaatggtttcctggcctgctcaacactgacatgcatggcaatggagaggctttg
ctgaagaagtgggttctctacagttttgaagatggccaggagttgaggaagattctgttg
gatgacctttacaggcattttgatcatgattttttgctggtgaacccagagaatccacgc
tataggctcccgatttctcagatcgccccagacctggtgctgagtgaccagcctgcagga
acattactggacagcgaggaattgaaagtagacctctccacagagaacagactagggaat
ggaggttttggaacagtttatcgaggagtttataaaaacgaagaagttgctgtgaaggtt
ttcaacaagcatgcttctgatctttatgtccacagactcctcagacaggaactggcagtg
ctaggtcgtctccggcaccccagcctggtgggcctgctggccggcagctccgctcctcag
gtcctggtgatggagctagctctcagaggctctctagactccctctttgaccatgagaat
ggtagcctcaaccgaaagctgcagcacaggatcgccctgcatgtggcagatggactcagg
tacctccattttgcaatgatcatatatcgggatctgaagccccacaacgtgctcctgttc
aacctgaaaactgactcagagatcatcgctaaaattaccgactatgggatcgctcagtac
tgttgtagcatgggagtgaggagctccgagggcactccaggtttccgagcacctgaggtg
gcccgaggtaatgtgatctacaaccagcaggctgatgtgttctcgttcggcctgctgcta
tacgacctgctgacgagcggtgagcgcatttcagacggcatgaagttccccagtgagttt
gatgaaatcgcagtgcagggaaagctgccagacccagtaaagcagtacggctgttcacct
tggccaaacttccaggctctgatgatggactgtctgagggaaagcccacaggatcgaccc
acctccgctcagctgttcgacaggctgaattcgggggagatgctctgcttaatgagtgaa
gtgaaggtttccagcatgttcagtgctcagtgcattacagtgagctgcaggagcagcagt
ggtcagagaacatcaagccaaacagcctggctcggcgggggcagcagctcccggaagaga
ggcttcatcacagctgtggacctgcagaccaacacggtcacctcaaaggaggtcgacacc
agtcccgtcctttgccttgcaacagtccggatcccaaacgatgaatctgattggctggta
gcaggcacacagtccggctccttgctggtcatcagcacccaggacgtttccacttggcac
cacctgcagagcgtcactgatgccgtcacctcactgtacttccatctacaccctcagcac
atccaaagaacaaattatttgttggtcgggaccgcagatggagttcttagtgtctatgag
gagtctgtactcatgcaggagaacggtcagccagttaaaactctcaccgtgggaaacatc
agcactccgctcatgtgtttgggccagtcgactcactccctggacaacaagtccgtctgg
gccggctgcgggaccaagatcctctctttctctgtcgactacgacgtctgcaagtccatc
gacacgagaccacaccccatcttccaccagcagcggcctctgagtagcgaggcgtttgtt
tcccgcatggtggtggacaaacatgtgtatcttagcaaagctgggacaccaactgttgag
gtctgggataagaggagtgagaggatggtggactgcatcaactgctctcagatcattagg
caagaatcgggctgcaggcggggcagcagagtagagctgccctctgaggcttcaccttcc
tgggccacagttaaggccttgatgatgcagaacactgcagctctctggatcggcactaga
gggggctacctgctcctgcttgagctctccaatcatcagaccctgcaggtcatggcacct
tcgtgtaattccatttgctccatctcctcagcattcaaacagtcgatgaactggaagaac
gcggtgctggttttgggccggaggctcccacgagacaagaatcaggatgatgaggagact
ttgctgatggtgtggaacagcatgctgcctcttgaggtcaaagacctgaaaaagcactgt
gagaagagagcgcgagcagcagccagaatgagagagcagctccatcacacctga
DBGET
integrated database retrieval system
