Gluconobacter oxydans 621H: GOX0154
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Entry
GOX0154 CDS
T00230
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gox
Gluconobacter oxydans 621H
Pathway
gox00300
Lysine biosynthesis
gox00550
Peptidoglycan biosynthesis
gox01100
Metabolic pathways
gox01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gox00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GOX0154
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GOX0154
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GOX0154
Enzymes [BR:
gox01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GOX0154
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AAW59947
UniProt:
Q5FUJ9
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Position
169379..170500
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AA seq
373 aa
AA seq
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MTALVDLGRNARARFRGKVVAITGSVGKTTTKDMLKVALSAIGPTHAAVASYNNHWGVPL
TLARLPQDARFCISEIGMNHIGEIAPLAAQVRPDVAIITTIGTAHLGHMGSIEAIAQEKS
DLFSALSDKGIAIVPDDAAGQEHFQTALPAGCALWRSGFSETAQLRIENLHCSAEGSHFS
LHLPSGIQNVTLTAPGEHLARNAALALGAVAALGEDVAVAATALQNFVPGAGRGQMRTIL
NDVRLLDESYNASTPSVRAALATLALLPAQRHIAALGDIRELGTFADAEHRSLADAVQNA
KAIAFCCGPHMRALYDALPSELQGGYAADAASLAPLLLKALRPGDLLLVKGSFGSRMRDV
ISVLDNASSPVSA
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atgactgcccttgtagatctgggccgtaatgcgcgcgcgcgttttcgcggaaaagtcgtc
gccatcaccggaagtgtcggcaagacgacgaccaaggacatgctgaaagtcgcgctgtcc
gccatcggcccgacgcacgctgcggtcgcctcctacaacaatcactggggcgtgcccctg
acgctggcccgactgccgcaggacgcccggttctgcatcagcgaaatcggcatgaaccat
atcggggaaattgctcccctcgctgctcaggtccgacccgatgttgcgatcatcaccacg
atcggcacagcacatctcgggcatatgggcagcatcgaggcgattgcgcaggaaaaatcc
gacctgttcagcgctctttcggacaagggaattgccatcgtccccgacgacgcagccggt
caggagcatttccagacagccctacccgcaggatgtgccctgtggcgttcgggcttctcc
gagacggcacagctccggatcgaaaatctgcactgctcggcagaaggcagccatttttcg
ctacatctgccatctggcattcagaacgtgacgctgacggcgccgggagagcatctcgcc
cgcaatgccgctctggccctcggcgcggttgcggctcttggcgaagacgtcgctgttgca
gccaccgcactccagaacttcgtgccgggtgcaggacgcggacagatgcgcacgatcctg
aacgacgtgcgccttctggacgaaagctataatgcgtccacgcccagcgtccgcgcggca
ctggcaaccctcgcgctgcttccggcccagcggcacatcgcggccctcggggacatccgc
gaactcggcaccttcgccgatgccgaacaccgttcgctcgcagacgccgttcagaacgcc
aaagccattgccttctgctgcggcccccatatgcgcgcactctatgatgcgcttccctcc
gagcttcagggcggatacgccgctgacgccgcgtctctggcgcctcttctgctcaaagcc
cttcgccccggtgatctcctgctcgtgaaaggcagcttcggcagccggatgcgtgacgtg
atctcagtcctcgacaacgcttccagcccggtttctgcctga
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