Garra rufa (doctor fish): 141283320 Help Entry 141283320         CDS       T11039                                  Symbol mdn1 Name (RefSeq) midasin   KO K14572   midasin Organism grf  Garra rufa (doctor fish) Pathway grf03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:grf00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     141283320 (mdn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:grf03009]     141283320 (mdn1) Ribosome biogenesis [BR:grf03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     141283320 (mdn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA_3 AAA AAA_7 AAA_16 TsaE nSTAND3 Sigma54_activat ABC_tran AAA_22 Mg_chelatase Sigma54_activ_2 AAA_14 Dynein_heavy DUF815 AAA_6 AAA_25 MDN1_4th PduV-EutP AAA_8 VWA_2 AAA_33 MCM VWA ATPase TniB Motif Other DBs NCBI-GeneID:  141283320 NCBI-ProteinID:  XP_073672706 LinkDB All DBs Position 13:3674085..3753512 Genome browser AA seq 5157 aa AA seqDB search MENLELSLTSLGAISRHIDKSQNELSKYLAKQIWSQQDRQCILESLAQLLLEKEYTLLIA RHLRPLILDLLERNAERIKADVRLNHDLHERLCVALSKLLNISPDAQAFAARYFCSSPPV FQRLFFTSEEAASIQYGPRRMKLRDLMGATLRFLQSDCEKFRVLWDWSACVSQLLTSDVM VRSYTAQCLALVSHMTDNQKTIFLRKVLSSEEILHLKMKSLEETQQLEVEKALVLANQGS AVWRKERVNKVTRGQVVTEDLTRSVTVVCGVILPRRAPRQDEQTSLSSLVLVDSTCQNLR RLAMAVASQKPILLEGPIGCGKTALVEYLAAVTGHIKAPDILKVQLGDQTDSKMLLGMYR CTDIPGKFVWQPGSLTQAVSKGYWILLEDIDHAPLDVISVLLPLMENKKLTIPGREDCIQ MAPSFQFFATRRTFYSGGAWHRPQSSHAALLDKYWSKLQIGNMSREELKQILMKKYPNLT VVVERLLDIYCQLTGDKHQSSSSLQGPSAAQNISDEHITSLEGRGLSLRDLLKWCERICL NFDSACASTAQNVFLEALDCFTAMLSKSESRLKMAEIIGSKINISKEKAQHFCQMYLPGI NVTELEVAVGRAMLLRKQTDAVRLSIGRQTFAATRPSSVLLEQLSVCVTKGEPVLLVGET GTGKTSTVQYLAEMTGHKLRVVNMNQQSDTADLLGGYKPVDQKLILLPLREAFEDLFSQT YSRKQNLTFLGHVQTCFRGKRWEDLLKLMDHVCKSALTKELHDKPNAALLQEQWEALALK LSQTQEQIRACESALVFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSGLLEGSAGS LVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEELETESDLRIL VSDYLKGLNLNRSIIHGVISFYLAVRKEANTRLVDGTGHKPHYSLRTLCRALKYVASDPC YNIQRSLYEGFCLSFLTQLDRSSHPVVQKLVCQYILGGNVKCLKQPIPKPKGRVCVQIEE YWLSRGDREPTVDHSYILTPSVKLNLKDLARVVAAGIHPVLIQGETSVGKTSLIKWLSGA TGNQCVRINNHEHTDIQEYIGCYSSDEQGKLVFKEGVLIDAMRKGYWIILDELNLAPTDV LEALNRLLDDNRELFIAETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHF DELPSAELENILHQRCSLPPSYCSKLIKVMQDLQSLRRGSSVFAGKHGYITLRDLFRWAE RYRLDEQTDTSRDWLQHLADDGYMLLAGRVRKPEEALTIQSIFEKHFKRTVNPDALFCEA QVTSQFSPFVDSIAGVPEEFGHVVWTQGMRRLAVLVGRALRFGESVLLVGDTGCGKTTIC QLFAALASQKFFSVNCHLHMETSDFLGGLRPVRHTGTQQADAEDGRLFEWHDGPLVLAMK QDGVFLMDEISLADDSVLERLNSVLETEKSLVLAEKGSGDDDDVELIIAGKKFRLVATMN PGGDFGKKELSPALRNRFTEIWCPQSNSRNDLMQIIQHNLRPGLSLDQHDHQGKDIAELM LDFIDWLTNQEFGRRCILSVRDILSWVNFMNTVCERDEDGFMTMGELEEEEPEWDLRLDT VTAFIHAACLVYVDGIGSGTTVSAAENALVARKLSMEYLEKRLSRITELDEEMQDALRVY DTSVPREPQWGEDFFGIDPFYIAAGPESEGRSLSDYALSAGTTAVNAQRILRALKLQRPV LLEGSPGVGKTSLVAALAKASGNHLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGP LLAGLKAGHWIVLDETTYMSKLQMDFTLLKERLAQMQDGWTHGGFEWLDGTLVQALQAGD WLLMDNVNFCSPSVLDRLNALLEPGGSLTINERGIIDGTTPTITPHPNFRLFLTMDPTHG EISRAMRNRGVEIYIPGEHEGVCWDTLDLKMVLHTLGVTGDCVCDLLIAIHSEIKNTIWD SPASCMSSLLHAASLLSGQLQRGVDLPSALLQACGEAYAFCQRTTANQQLAQEVIERQLA VLDSEDWGSGLLCAGVWPDRIPSALLCTEDSCFSSVQRDGQVLLYCLNTLSLYGKRNRPL SLVDLQRAMQSGAVLDGLQFSGGGELDGGAENTLCLLPTAVKILTERASHSDWVLRTSWL SHLTKTYKHAPDAALMQLEAGCTALKSVFSSKLIGKGKCLAELLQPHSTDDYRILVDMRW NKQYLDILANTCNFEDEERYMEFMEALNAVANRITLLMDREERTAINSSAGNSSPHNSAL RLATAFSKGTVDIGHLPHPVLVHLRSFFDLWDSFVLQAVQSGQPYISDHLMFEILQLLQW RDRFWHVCNSLSADTRGVCVMSLHWQWVHKNLILRLPQLLMGDSDYEGQQELHTISTAIQ NTLSSSVAVASALKGIQKTLGKPLPFKLEAVAECAARLRVLCRALDVRDLRLDNSLASLW KQEVSRLRGVAMGIDSKEALLEAWGLVLQANLLLEPQNSGVLERLVSCVDQQQGHMASCG LLDSLSEDNEEEVGDSAAPGQEMLLQLARRAQLWPALEELAVLNQMKVTTDLLYLSLTPR SSKKAEDDLRRSFSNHLRFCMQSTPMNIRQLQPLCFLLGTERPVEELPLVWCELLSETLA ALWSGSVTSDPDRWLKWNPLNPEEHMNSRSPLGPSDTGPGMLSHAVWSRCMLGVLSNTDA GGRWDPSGSHFLSSSRVTLGEWRERTGQLQDLSAVIWDNMAMLELADFRSTDCRLQGLVL RRQMQSLSELLSPGLQESYAESCDSLTESQDPIAAAQEIQISLKEGLPENLLPEGFLDTL VTCLTQFAHNRAQDSVQLARSGVFWVNMGLLQIQVWAPQTIFDPAVKRAYKLRYAQEELA LLQEEWRGRSLSSQMLTGAELEESSTTDNFQHPRIRYLWIRMQQVKEQICELSRKQACRP PDPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQAPGPKSRLGIQGLLKEEAVWQAS QHRFTQRLVEEYPLYPDVVVPLRAAILQVQHGMRLLASQVSSSMTAQPGLARLVSTMLAF PSPAASSDLACADYLCSRECLHMLKGLGKQLPAAEVSRVIPDHAVLLLNALLYIQSHTLS AGHLSAETQKLFRHVCQAIVNEWDEQEKRAREKEQMEASLYRNRTRLHGTGLTEDQQEER EFRRSFPSYHKDFADITSEPSLDQPIIIEDDDDVDSEESSSETSGFLLVSSMSTVVQVHQ RLCLSYAQSLWYQPNMPINHTKDHVSALVSSYQSTAPLIARFYHLMDCEVDAKLMGSQLL LSTLLQNTVTGSGGPAELILQGDGPYDFYRDPNMSQARICLPALEQLSKAVRQRLNDWPE HPALVQIIIVIERILAFSLSSPLAKFLNGLEILLSKSQDWENNASRAVSLRNELEAITQL IIQWRKLELNCWSSSLDNALKRHAENSTKHWLSIYQLIERYLQEQRTDSRHDDAVEHLSL SSISSTLQAFIEGSTIGEFSIRLSMLLGFHCHVLLAPKQEGHESLCSLLWNLYKYYTQFS ESIQAKITQLRSPIEKELKDFVKISKWNDVSFWSIKQSVEKTHRTLFKFVKKFEAALKEP CTPCLVERGSSSSMDDVDSQPEDTPLHKVHRALKTALPGKGRDLQADGPEELSSDKEPSS LQGRLPVLTRKMKKLCVQLVKKTSLPELSEDLDQFTAEIITNVQALQSLTVDRSVEQEKQ KAEVKHILLQKQRALADLFKMLAQIGLSYRKGLNWAHTADPDETLCLQPMEMKIALSAVK TQDNTEHTLFAEMMDAWEGCEKYYYRSWARRNAMLTALQSSVKELGLGNIQRCRGFSSHL FKLLLRQRRRLAGLTQNWVQLRKLIDCIQSIKSDTPGSEDEVGGLPPQKPLQHWISRAQS SALHCSVVLQQLSWILQCCPEGSSAAPAEAREGEVLQGQATLSHPSPLSPHIQPQACLLR RGEQAWREVQQKVENLVKEVKDLKEKLDGLAHESTERVIQSWDHFTLCCSSLDRLGMVVG QMPALEQLFIPDGVPVLQTQPALIFGLQSVRTEVDTCLTEFTTWKTHLLSIRQSQKRHSH PFSAEFSGQLEKAINMVLCAVQTLVKRKEKEKQEDQQPETKRESESEVAEDLLKPGHLSR LLEEDLSGDVSSLSLPEVNGVVTELLERLRSHRDDCRPNQLQELKEACRGVVRLEPMLCL YSELVRYYLAVLTGAHRTTGKLLSVLANIFTELAQKGFCLPQELMGGGDGEGATEFHDYE GGGIGEGEGVKDVSDKIENEDQVEDTFQEGQEKKEEEQNKQDVKEEDNAIEMSEDFDGKM HDGTDREPGENEEDSDKEEDEELDKKMGDLGDGQTETLDERMWGDDEDDDDDVDSDIEEE SGPGMDQGESELVAKDDNMDAGESNKDKNQDKNQPKDEEEKDKIHEQMDEREFDENEVDP YHGKQEKAAETETIDLPEDLNLDEDGKDDEEGGEGDEENPFDIDDKLMEVDEKKEEEKDG SEEGGDEKADEQQEGQIDEQGEEDKSEEAEKSENQEPETDEKGENEEAEEEQEEKNQGQE EGREENKSIPADQGQKPKEEENEAEEDEAQMESAERKEHASDGQTGEENVQSDTAVELAG AASEKDQAKEEDGSGAADASQSEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERSMG DYNERVNKRLRTVDNREEKTQDQSQPNTQQESDLYEHVKQGEERYDAQTYDAASAEQQNP TGVKQEDEEEDIAMDVEEEKDLHAGEAQELKPEKLNDNKASQKGLECGDMEAQKQADEEE MEKPETERSSNEEEMKERSDESTIHTVPELLMDVQKVPLKNPEELRREMELQLEAWQRQT LGSPEEESAAAALWHKYQTLTSPLSQQLCEQLRLVLEPTQAAKLRGDFRTGKRLNMRKVI PYIASQFRKDKIWLRRTKPSKRNYQICLAVDDSSSMVDNHSKQLAFESVSVIVNALTLLE VGQVSVCSFGENVQLLHPFHQQFNDQTGAKILRLCQFQQKKTRIAQFLETSTSMFMAAKQ QTPGSTNTETSQLLLIVSDGRGLFLEGKERVAAAVQAARSANIFVIFVVLDNPNSRDSVL DIKVPIFKEPGELPEIRSYMEEFPFPFYVILRNVNALPETLSDALRQWFELVIATDQ NT seq 15474 nt NT seq  +upstreamnt  +downstreamnt atggaaaacctggagttgagcctgacatctctaggagcaatctcaagacatatcgataaa agtcagaacgaactcagcaagtatctcgcaaaacagatatggagtcaacaggacagacag tgtatactggaaagtcttgcacagcttctgttggagaaggaatacactctcctcattgcg cgtcacttacgaccactgatcctggacctgttggagaggaacgctgagaggatcaaagca gacgtcaggctgaatcatgacctccatgagcgcttgtgtgtggctctaagcaaacttctc aacatcagtccagatgctcaagcgtttgcagcaaggtatttctgtagctctcccccagta tttcagaggctgttcttcaccagcgaagaagctgcttccatccagtatgggcccagacgg atgaaattacgggaccttatgggggccaccctccgcttcctccaaagtgattgtgagaag tttcgtgtcttgtgggactggagtgcctgtgtttctcagcttctcaccagtgacgtcatg gtcagaagctacacagcccagtgccttgccctggtgtcgcacatgacggataaccagaaa acaatatttctgaggaaggtcctttcgagtgaagagattctgcatctgaaaatgaagtca cttgaggagacacagcagctggaggtagaaaaagctctggttttggccaatcagggctca gcagtgtggcggaaagagagggtaaataaagtcacccgtggtcaagtggtgacagaggac ctgacgcggagtgttactgtggtttgtggggtgattctgcctcgacgtgcccctcgacag gatgaacagacaagtttaagcagcttggtgttggtggattcaacctgtcaaaatctccgg cgactcgccatggctgtggcatcccagaaacccattcttttagaagggccaattggatgc ggaaaaacagctcttgttgaatatcttgctgcggtcactgggcacattaaagcccctgac atccttaaagttcagcttggagatcagaccgacagtaagatgttgctgggtatgtaccgc tgcactgatattcctggaaagtttgtatggcagccaggatcactgacccaggcagtctca aaaggttattggattctgctggaggacattgatcatgctcccttggacgtgatatcggtt ctgcttcctctcatggagaacaagaaattgacgattccaggacgtgaggactgtatacag atggctccatcattccagttttttgcaacacgaaggacattttacagcggaggagcctgg catcgaccacagagttctcacgctgcacttctggacaaatactggagtaaactgcagatc ggcaacatgagccgagaggaacttaaacagatcctaatgaagaagtaccctaacctgaca gtggtggtagagcgtcttttagacatatactgccagctaacaggagacaaacatcaatcc agctccagtctgcagggtcctagtgcagcccaaaacatatcagatgagcacatcacatca ctggagggcagaggcctctcacttagggacttgctgaaatggtgcgagagaatctgttta aattttgacagcgcttgtgcttccacagcacagaatgtgtttctagaggctctggactgc ttcactgccatgctctccaaatccgagagcagactcaagatggcagagatcattggcagc aaaatcaacatatccaaagagaaggcccagcacttttgccagatgtacctgcccggaatc aatgtgacggagctggaggtggcggtgggtcgtgcgatgttactccgcaaacagaccgat gcggtgcggctgagcataggcagacaaacatttgctgccacacggccatcctccgtactt ttggagcagctctcggtgtgtgtcactaaaggggaacctgttttgttggttggggagacg ggcacaggaaagacctctactgtgcagtaccttgcagaaatgacaggacacaaactcaga gtggtcaacatgaaccaacagagtgacacagccgacttactaggagggtataaaccagtg gaccaaaagctcatcctgttgcccctgcgggaggcctttgaggacctcttttctcagaca tactcacggaaacagaacttgaccttcctgggtcatgtccaaacctgcttcagaggcaaa cgctgggaggaccttctgaagctcatggaccatgtctgcaaatcagcactaaccaaggaa ctacatgacaaacccaatgctgccttgctgcaggagcagtgggaggctttggctctcaaa ctcagtcagacgcaggaacagattcgggcctgtgaatccgctttggtctttgcgtttgtt gaggggactttagcccaggctgtgaagaaaggtgaatggatcctgctggatgagattaat ctggctgctgcagagacgctggagtgtctgagtggattgctggagggcagtgccgggtca ctggtgctgctggatcgaggcgatactgagcctttggttcgtcatccagacttccgactg tttgcctgcatgaatccagccactgatgtaggcaagaggaacctgccactgggcattaga aacagatttacggagttgtatgtggaggagctggagactgagagcgatttacgaatcctg gtctcggactacctcaaaggccttaacctgaacagaagcatcatccatggagtcatcagt ttttatttggctgttcgtaaggaggctaacactcgtttagttgatggtactggtcacaag cctcactacagcttgcgtactttgtgccgagctctgaagtacgtggcctctgacccctgc tacaacattcaacgctccctctatgagggtttctgtctgagttttctgactcagctggat cgcagctctcaccccgttgtgcagaaactggtgtgtcagtacatactaggaggaaatgtc aaatgtctgaaacagccgatcccaaagccaaagggccgcgtgtgtgtgcagatagaggag tactggctgagtcggggtgacagggagcctactgtagaccacagttacatcctcacaccc tccgtcaagctcaacctgaaagatctggcacgggtcgtggccgctgggatccatccggtg ctcattcagggggaaacatctgtaggaaagacgagtctgataaaatggctctcaggtgcc acaggaaaccagtgtgtgcgaatcaataaccatgagcacactgatatccaggagtacatc ggctgttactcctctgatgagcaaggcaaacttgtcttcaaagaaggcgtgctgatcgat gccatgcgaaaaggttattggatcattctagatgaattgaaccttgcccccactgatgtc ctcgaggctctgaatagattgctggatgacaaccgggagctcttcatcgctgagacacag gaagtggtcaaagcccaccccagattcatgctctttgccacccagaatcctcctgggctt tacgggggcagaaaggttctgtctcgagcgtttaggaaccgttttgtggagctgcatttt gatgagctgcccagtgcagagcttgagaacattctgcatcagcgctgcagtttaccccca tcctactgctccaaactcatcaaagtcatgcaggacctgcagtccttacgcaggggatcc agtgtgtttgctggaaagcatggatacatcactctaagagacctgtttcgctgggctgaa cgctataggctggatgagcagactgacacatcgcgtgattggctacaacatctggcagat gacggctacatgctgttggctggtcgtgtcaggaagccagaggaagcgctaaccatccag agcatttttgagaagcactttaaaaggactgtgaacccagatgctcttttctgtgaagct caggtcacctctcagttcagccctttcgtggacagcattgcgggtgtccctgaagagttc ggccatgtggtgtggacccagggcatgaggagactggctgtgcttgtgggacgagcacta cgttttggagagtctgtcctacttgttggggacacgggctgtggtaaaaccaccatctgc cagctgtttgctgcattagctagtcagaagttcttctctgtgaactgccacttgcatatg gagacgtctgactttctgggtggccttcgacctgtccgtcacacgggaacccaacaggct gatgcagaggatggccgtctgtttgaatggcatgatggaccgctggtactggcgatgaaa caggacggcgtgtttctaatggatgagatctcacttgcagatgactctgtgctggaacga ctcaacagcgtgttggagactgaaaaatctttggtgctggcagagaaaggcagcggagat gatgatgatgttgagctgatcattgctgggaagaagttccggctcgttgccaccatgaac cctggaggtgattttggaaagaaagagctatctccagcactcaggaacaggttcacagag atttggtgccctcagagcaacagtcgtaatgatctaatgcaaatcatccaacacaatctg aggcctggactctctctggaccagcatgaccaccaaggtaaagacatagcagagctcatg ttggacttcatcgactggctgaccaatcaggagtttggtcgacggtgtattctaagcgtg cgagacattctgtcatgggtgaacttcatgaacacggtgtgtgagcgggatgaggatggc ttcatgaccatgggagagctggaagaagaggagccagaatgggacctgagattagacacc gttacagcctttattcacgctgcgtgccttgtgtacgtggatggaatcggctcaggaacc acagtgtcagcagcagagaatgccctggtggcacggaaattgagtatggagtacctggag aagagactgagcagaattacagagctagatgaggagatgcaggatgcgctcagagtctac gacactagtgtcccccgagagccccagtggggtgaagacttctttggcattgaccccttc tacattgctgcaggtcctgaaagtgaaggcaggagtctgtcggactacgctttgagtgca ggcaccactgcagtgaatgctcagaggatactacgagcgctgaagcttcagaggcctgta cttcttgagggctcacctggagtgggcaaaaccagcctggttgctgccctcgccaaggcc tctgggaaccatctcgtcaggatcaacctgtctgagcaaactgatgtaacagatctcttt ggcacagacctgccggtggaaggtgggaaaggaggggagtttgcatggcgtgatggtcct ctccttgcagggctgaaggctggacattggatcgtactggatgagaccacatacatgtca aagctgcaaatggacttcactctactgaaggagcgtttggctcagatgcaggacggctgg actcatggtggctttgagtggctggatggcacattagttcaggcgctgcaggctggagac tggttgctcatggacaatgtcaacttctgcagcccttcagtattggatcgactgaacgcc cttctggagccgggcgggtcattaaccattaatgaacgaggaatcatcgatggaaccaca cccaccatcaccccccaccctaacttcaggttgttcctcaccatggatcccacccatggg gaaatctctcgagccatgagaaaccgtggtgttgagatctacatccctggcgagcatgag ggcgtgtgctgggacactctggatctaaagatggtgttacacaccctgggtgtgacggga gactgcgtttgtgacctgctcatcgccattcattcagaaatcaagaacaccatatgggac tcgcctgcgtcatgcatgtcatctctactccacgctgcgtctctgttgtctggtcagctt cagagaggagttgatttacccagtgcccttcttcaggcctgtggtgaagcttatgctttc tgtcagcgcaccactgctaaccagcagctggctcaggaagtcattgagaggcagttggca gtgctggactctgaggactggggcagtgggctgctgtgtgctggcgtgtggccggaccgc atcccttcagccctgctgtgcactgaggactcctgtttctccagtgtccagagagacgga caggtcctgctatactgcctcaacactctcagtctttacggaaaaaggaatcgtccactg agcctggttgacctgcagagagcaatgcaaagtggtgctgtgctggacggcctgcagttt tctggaggtggagaactggacggtggagctgagaatacactgtgccttctcccaactgca gttaaaatactgacagaaagagcttctcacagcgactgggtcctcaggaccagctggctc tcacacctcaccaaaacatacaaacatgcaccagatgcagctctgatgcagttggaagca ggatgcacagcactgaaatccgtattcagcagcaagctcatcgggaaaggcaaatgtctg gcagagctcttgcaaccacacagcacagatgactacaggattctagtagacatgcggtgg aacaagcagtacttggacattttggccaacacctgcaactttgaggatgaggagagatac atggaattcatggaagcactgaacgctgttgccaacagaatcacactgctgatggaccga gaggagagaacagctattaacagcagtgctggaaacagctcgcctcataacagcgctctt agactggccactgccttctcgaaagggacggttgacattggccacctgcctcatccagtg ttagtccacctgcgctcattcttcgacctgtgggattcattcgtactgcaagctgtgcag tcaggccagccatacatctccgaccacctcatgtttgagatcttgcagctactgcagtgg agggatcgtttctggcatgtgtgtaactctctgtctgcggacactcggggtgtctgtgtg atgtccctgcactggcaatgggtgcacaaaaacctcattttgcggctacctcagcttttg atgggggatagtgactatgaaggccaacaggagctacacaccatttccacggccatccag aacacactttccagctccgtggctgtggcctctgctctgaagggcattcagaagacattg ggaaagccactgccgtttaagctggaggcggtggctgaatgtgcagcccgtctgcgagtg ctgtgcagggctttggatgttagggacctgcgcctcgacaacagcctcgcatcgctttgg aaacaagaagtgtctcgtctccgtggggtggccatgggaattgactccaaagaagcctta ctggaagcttggggtttggtgcttcaggccaacctcctgctggagcctcagaactcaggt gttctggagaggcttgtgagctgtgtggatcagcagcagggtcatatggcttcctgtggc ctgctggactctctttcagaagataatgaggaagaagtaggagacagtgccgcaccaggc caggagatgttactgcagctggcacgcagggctcaactgtggcctgcactggaggagctg gcagtcctaaaccaaatgaaagtcaccacagatctgctgtacctgtcactcacaccaagg agcagtaaaaaggcagaagatgatctccgcaggtccttctccaaccatctgcgtttctgt atgcagtcgacccccatgaatatccgacagctgcagcctctctgcttcctgctgggcact gagcggcctgtagaggagctgccgctggtgtggtgtgagcttctgtctgagacactggca gcgttatggagcggcagtgtgacctctgaccctgaccgctggctgaagtggaatccgttg aaccctgaggagcacatgaactctagatcaccgttggggccatctgatacgggtcctggc atgctgagtcatgctgtgtggtcccgctgcatgctgggagttctgagcaacactgatgct ggcggccgatgggatccatcggggtcacacttcctgtcatcatcacgggtgaccctgggt gagtggagggagagaaccgggcagcttcaagatctgagcgctgtgatctgggataatatg gccatgcttgagcttgctgacttcagatcaactgactgtaggttgcaaggacttgtgttg cgacgtcagatgcagtctctctctgagctgttgtctccaggtttacaggaaagctatgca gaatcctgtgacagtttaactgaaagccaggatcccattgctgcagcccaggagattcag atctccctcaaagaaggcctgccggaaaacctgctcccagagggctttctggatacccta gtgacatgcttgacacagtttgcacacaaccgggcacaggattcggtccaacttgcccgg tctggagttttctgggtgaacatgggtctgctgcaaatccaagtttgggctccacaaaca atatttgacccggcagtaaaaagggcgtataaactccgctatgcacaagaggagcttgct ttgctacaggaagagtggagagggcggagtctgtcctcacagatgctcacaggggcagag cttgaggagagtagcacaaccgataacttccaacatcctcgcatcaggtacttgtggatc cgtatgcagcaggtgaaggagcagatttgcgaactgagtcgtaaacaagcctgccgcccc ccagacccccaatatggccgtctgtatcaagaactccagcactacctgtgcagcattggc caaccagccgcagtgggcgacctgctctcccacctcctgaaggccttacaggccccgggg ccaaaatcaaggctgggaattcagggtttgttgaaggaagaggctgtgtggcaggcttca cagcaccgctttacccagcgtctggttgaggagtacccgctctatcctgatgtggttgtg cctctacgggcagcgattttgcaagtacagcacggcatgcgactcctggcttctcaggtg tcctcctcgatgactgcccaaccgggtctggcacgactcgtgtccactatgctagctttt cccagtccagcggcatcctctgatctggcctgtgcggactacctgtgttcaagggaatgc ttgcatatgctaaagggcctgggaaagcagttgcctgcagcagaggtcagccgtgtaatc ccagatcatgcagttttgttgttgaatgcgctgctgtacatacagagtcacacactgagt gccggacatctcagtgccgagacgcaaaaactcttcagacatgtttgccaggctatagtg aatgaatgggacgagcaggagaagagagcgagagaaaaagagcagatggaagctagtttg taccgcaatcgcactcgtctacatgggacaggcctaacagaggaccagcaggaagaaaga gagttcagacgctctttcccctcttaccacaaggattttgctgatatcacttcagaacct agtctggatcagccaataatcatagaggacgacgatgatgtggattcggaggaatcgtct agtgagacgagcggcttcctgttagtcagcagcatgagcacagtggttcaggtccatcag agactctgcttgtcctacgctcagtcactgtggtaccagcccaacatgccaattaaccac accaaagaccacgtcagtgccctggtttcatcctatcaaagcacagcgccactgatagcc cgcttctaccatctaatggactgtgaggtggacgctaagttgatgggctctcagcttctc ctcagcactttgctccagaacactgtgactggttctggaggtccggctgaactgattctc cagggtgatgggccgtatgacttctacagagaccctaatatgagtcaggcccggatctgt ctgccagcgctggaacagctgagtaaggctgtgagacagcgcctgaacgactggcccgaa caccctgcgcttgttcagatcatcatagtaatagagaggatattggcgttcagtctgtcc agccctctagcaaagttcctaaacggtctggaaatcctgctcagcaaatcacaggactgg gaaaacaatgctagccgggctgtgtctcttaggaatgagctggaagctatcacacaactc atcatccagtggagaaaacttgagctcaactgctggtcgagcagcctagataacgcattg aagcgccatgctgagaattcaaccaagcactggttgtccatttaccagctcatagagaga tacctacaggagcagaggactgactccagacatgatgacgccgtggagcatctttccctc tcgtcaatctcatccaccctgcaggccttcattgaaggctccaccataggagagttttcc atccgcttgtccatgttgcttggttttcactgccacgtcctgctggctcccaaacaggaa ggacatgagtcactttgcagtctgctgtggaatctctataaatattacacacagttctca gagagcatccaggccaagatcacccagctgaggtctcctatagagaaagagctcaaagac tttgtcaaaatctccaagtggaatgatgtcagtttttggtccatcaagcagtcagtggag aaaacacacaggaccctgtttaagtttgtaaagaagtttgaggcggcactaaaggagccg tgtacaccgtgtctggtggagcggggcagtagcagcagcatggatgatgtggattcacaa cctgaggacactcctctgcacaaggttcatcgagcactgaaaactgccctgcctggaaag ggcagagatctacaggctgatggtccagaggaactctcgtctgataaagagccctcatct ctccaaggccgtctgcctgtcctcacaagaaagatgaagaagctgtgtgtgcagctagta aagaagacctctcttccggagctctcagaagacctggatcagttcacagccgagatcatt accaatgtgcaagccctccagagcctgacggtggaccgcagcgtggagcaggagaagcaa aaggcagaggtcaaacacatccttctgcagaaacagagagcgcttgcggatctcttcaag atgcttgcacagattggtctgtcctatcgtaagggtctgaattgggctcatacagcagac ccagatgagacgctgtgtctgcagccaatggagatgaagatagccctgtctgcagtcaag acacaggacaacacagagcacacgttatttgcggagatgatggatgcatgggaaggctgt gagaagtattactatcgatcctgggccagacgcaacgccatgctgacagcattacagagc tctgttaaggagcttgggctgggaaatatacagcgatgtagaggtttctcttctcacctg tttaaacttttgctgaggcaaagacgaagacttgccggactcacacagaactgggtccag ctcaggaagttgattgactgtatccagagcatcaagtccgacacgcctggctctgaagat gaagtcggcggtctccctcctcagaagcctctccagcactggatctcgagagctcagtct tcagcgctgcactgctctgttgtgctccagcagctgtcttggatcctccagtgctgtcct gaaggttcttctgcagcccctgctgaggccagggagggggaggtcctgcagggtcaggcc acactgagccacccgtctcccttgtccccacacatccagccacaggcctgcttgctgcgg agaggggagcaggcttggagggaggtgcagcagaaggtggagaacctagtgaaggaagtg aaagacctgaaagagaagctggatggattagcccatgaatccacagaaagagttatacaa agctgggatcacttcacactttgctgttcctctctggaccgactgggcatggtggtgggt cagatgccggctctagagcaactctttattccagacggtgtgccggtcctccaaacccag cctgccctcatcttcggcctccagtctgtaaggacagaggtggacacctgcctcacagaa ttcaccacctggaaaactcacctgctctctatcagacaatcacaaaaacgacattctcat ccattttctgctgagttctccgggcagctggagaaagcaataaacatggttctgtgtgcg gttcagacacttgttaagagaaaggagaaggaaaaacaggaggatcagcagccagaaacc aagagagagagcgaatcagaggtggcagaggaccttttgaaaccgggacacttgagcagg ttactagaagaggacctgagtggagacgtatccagtctgtcattaccagaggtcaatgga gtcgtgacggagctgctggagagacttcgatcacacagggacgactgtcggcccaaccaa ctacaggagttgaaagaggcgtgtaggggtgtggtgcgtctggagcccatgctgtgtctg tactctgagttggtgaggtattatctggctgtactgacgggagctcaccgcaccactgga aagctgctgtccgtcctcgctaacatcttcactgaactcgcacagaagggtttctgtctg ccccaggagctgatgggaggaggagatggtgagggagcgacagagttccatgattatgag ggtggaggaataggagaaggagaaggagtgaaagacgtcagcgacaaaatcgagaatgag gatcaggttgaagacaccttccaggagggtcaggagaagaaggaggaagagcaaaacaaa caggacgttaaagaggaggacaatgccattgaaatgtctgaagattttgatgggaagatg cacgatggcacagaccgtgagccaggtgaaaatgaagaagactctgataaggaagaagat gaggagctggataagaagatgggtgatctgggtgatggtcagacagaaactctggatgag agaatgtggggagatgatgaggatgatgacgacgatgttgacagtgatatagaggaagag tctggtccaggaatggatcagggagagtcagagctggtggcaaaggatgacaacatggat gctggagagtcaaacaaagataagaaccaggataaaaatcagccaaaagatgaggaagaa aaggacaaaatccatgaacagatggatgagcgtgagtttgatgaaaatgaagtagaccca taccacggtaagcaggagaaggcggcagaaacagaaaccattgatctgccagaagatctc aacctagatgaagatggcaaggatgatgaagaaggaggagaaggagatgaggagaatcca tttgatatagatgacaaactcatggaggtggatgagaaaaaggaagaagagaaagatgga tcagaggaaggcggagatgagaaggcagatgagcaacaagaaggacaaatagatgaacag ggagaagaagacaaatcagaagaagcagaaaaatctgagaatcaagagcctgaaacagat gaaaaaggagagaatgaagaagcagaggaggagcaggaggagaaaaatcaaggacaggaa gaagggcgtgaggagaacaagtccataccagctgatcaagggcaaaaaccaaaggaggaa gagaatgaggctgaggaggatgaggcacagatggaatctgcagagaggaaggagcatgcg tcagatgggcagacaggagaggagaacgttcagagtgacaccgcagtagagctggctgga gctgcgtcagaaaaagaccaggcaaaggaggaggatggcagcggtgcagcggatgccagt cagtctgagggacatgactccaagctgatggcgaggatgagttcacaaaaacagaggcag aaaaacacacagagcttcaaacgcaaacctggacaggccgataacgaacgctcgatgggt gattataatgagcgtgtgaataagcgcttgcgtacggttgacaacagagaggagaaaaca caggatcagtctcagcccaacactcaacaggagtctgacctgtatgagcacgtaaaacag ggagaggagagatacgatgctcagacatacgatgctgccagtgcagaacagcagaacccg actggcgtgaaacaggaagatgaggaagaagacattgcaatggatgtggaggaagagaag gacctgcatgctggtgaagcccaggagcttaaaccagagaagctaaacgacaataaagct tctcagaaaggtttggagtgtggggacatggaggcacagaaacaggccgatgaggaagaa atggagaagccagagacagaaaggagcagtaatgaagaagagatgaaagagaggagtgac gagtccaccatccacactgtgcctgaactactgatggacgtacaaaaggtacctctgaag aacccagaggagctgagaagagagatggagctgcagttggaggcctggcagagacagact ttaggatccccagaagaggagagtgcggcagcagcgctgtggcataaataccagaccctg acgtctcctctgtcccagcagctctgtgagcagcttcgccttgtcttggagcccacacag gctgccaaactcaggggagacttccgcacaggcaaacggctgaacatgcgcaaggtcatt ccttacatcgccagtcagttccgcaaagataagatctggctgaggagaacaaaacccagt aagagaaactaccagatctgcctggctgtggatgactcttccagtatggtggacaaccac tccaaacagctggcctttgagtcggtttctgtcatagtgaacgctctcacacttttggaa gtgggtcaggtgtctgtgtgcagttttggagagaatgtccagctgctgcatcccttccac cagcagttcaatgaccaaacaggagcaaaaatactgcggctctgtcagttccagcagaaa aagaccagaatagctcaatttttagagacttcaacaagtatgttcatggcagccaaacag cagacccctggctcgacaaacactgaaacgtctcagttgctgctaatagtatctgatggt cgtggtttgttcttggaggggaaagaaagagtcgcagctgccgttcaggctgctcgcagc gcaaacatctttgtcatatttgtagtgctggataaccccaactccagggactccgtattg gatatcaaagtgcccatatttaaagagccgggtgagctgccggagattcgatcctatatg gaggagttccccttccccttctacgtgatcttgcgaaatgtgaacgccctcccagagaca ctgagtgatgctttgagacagtggttcgagctcgtcatcgccacagaccagtaa

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