Garra rufa (doctor fish): 141284668
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Entry
141284668 CDS
T11039
Symbol
arhgef12a
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
grf Garra rufa (doctor fish)
Pathway
grf04270
Vascular smooth muscle contraction
grf04625
C-type lectin receptor signaling pathway
grf04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
141284668 (arhgef12a)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
141284668 (arhgef12a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
141284668 (arhgef12a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
grf04131
]
141284668 (arhgef12a)
Membrane trafficking [BR:
grf04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
141284668 (arhgef12a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
Motif
Other DBs
NCBI-GeneID:
141284668
NCBI-ProteinID:
XP_073673760
LinkDB
All DBs
Position
14:complement(21824472..21905583)
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AA seq
1390 aa
AA seq
DB search
MSDTRSTVPDRTSSILSRDHPPDKRPKSDKLPSTPTHEFDPTDVLVEKSGFVVADRRPES
CGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKQDGAAMRAGVQTGDRIIKVNGTLVTQS
NHVEVVKLIKSGSYVALTVLGRPPGLPQIPLSEVDIGLGSPGGYRDSFVTSPNSYKAAER
TSSPLVSWEENSVPLNQRMDNRRMLSKEQQDIQGLREDYGRIPTPKPLRDIQEAKKHIPH
QPGHIHESLYLRNSEDGCWVDEDQYKGDFSPEGFWSGGSVSSVPRQFYPASPESQRDSSC
YSPKSTPRDSLNSCPSPDVEDGSDLDSRFSSTIGSPPSRLASEIIAAEDDDFDPEQEQVN
GQCSCFQSIELLKTRPAHLAAFLHHVISQFDPAPLFCYLYADLYKQTNSKETRRIFTDFL
TFFLDRGANLKVAVPESISSELERRRPELIPEELHRQFIQTMQETLLPDVQRNLEDFRQK
RSMGLTLADVELSRLDSEQPALERERSCAENILSKIDDVLLTSQPAEEEKCNTIQYVIFM
YMKHLGVRVKEQRNLESKRVRINFLPSKLRKSKTEKEGEEKLKKPRFPIRVPPRWPSRLD
SVPSGRAGDNIKHRPQKQMSQPALGGSELIEGGRLRGSQSSEGSDLLHSPSLITSPPFSA
TYGLPSDPSGRDPEFSMSPSAVVPRLSDGLQSGDVLDSIYPPCDYIPYNMDQLDEDGDRL
LDVGTPKLSRRFEELQSEDDQGSDVYSDVDPPNWQQLVGRDVLAGLTPHEIKRQEVINEL
FYTERAHVRMLKVLDSVFYQKLTRDNILPPADIKNIFTNLEEIIQLHLRIADQMTTIRKK
NESSVIDHIGDELLSWFSGGEEEKIKQAVGTFCSNQPFALELIKSRQKKDQRFTSFMQEA
ESNRLCRRLQLKDIIPAEMQRFTKYPLLMDNIVKYTDESEEKDKVRRAAECCRHILSHVN
QSVKESENKQRLEDYQRRLDLSSLKQSENPMISEFKNLDLTKRKMVHEGPLSWKINKDKT
IELYTLLLEDILVLLQKQDERFILRCHSKNLAGTADTKHIFSPIIKLGTVLVRSVATDNR
SFFVISMSKNGAQIYELMAQTVSEQRMWQRQIAQRAEVMNGKPHSVIPLPQHDVDRDSVE
LSKFSKGSERISTGSIQSAEKDSEFSPTAALRDCVPDSNPGEEDQVPRAGRDASYLDSEL
LNGRDADSLSCSSKADEALKTLAALKQVLVTQLMAQDEGERLCRSAGSRLLRTTSLRTPV
EHSSTRTPSRAQDYTSGDTGFYECPEDYAAYLVLEGYGGPGESSTDDDIQVRRKESSLAH
SCAADSGISLKFSSPSSGSTSRLSRQVLSHLRCLQANLNHLKEMETKYYNLLRQRPVGSA
ADPDESRDKK
NT seq
4173 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacacacggtccacagtccctgacagaaccagtagcattctcagcagagaccac
cctcccgacaagaggcccaaaagcgataagctgcctagtaccccaacacacgagtttgac
cctacagatgtgctggtggagaagagtggatttgtagtggctgacaggagacctgagtct
tgtgggctggttcagagatgcgtgatcattcagaaagatgagaacggctttgggctgacc
gtcagtggggacaaccctgttttcgtgcagctcgtcaaacaggatggcgctgctatgcgt
gcaggtgttcagacgggggacaggatcattaaggtgaacgggacactggtgacgcaatca
aaccatgttgaagtggtgaaattaatcaaatccggctcatatgtggccctcacagtatta
ggccggcctcccgggttgccccagatccccctctctgaggtagacataggtctcgggtca
ccagggggttatagggactcttttgttacatctcccaactcttacaaagcagctgaacgc
acctcctctcctcttgtatcatgggaagagaacagtgttccactcaaccaaagaatggac
aacaggaggatgctgtccaaggagcaacaggacatacagggactgagggaggactacggc
agaattccaacacccaaaccactacgggacatccaggaagccaagaagcacattccacat
cagccgggccatatacatgaaagtctgtatctcaggaacagtgaagatggctgttgggtg
gatgaggatcaatataagggagatttcagcccggagggtttttggagtggaggttcagtg
tcatctgtcccgcgccagttctacccggcctctccagagagtcaaagggattccagctgt
tacagtccgaagagcacccccagagacagcctcaactcctgcccctcccctgatgttgaa
gatggctctgacctggattctcgtttctcatccaccatagggagtccaccctcccgcttg
gcttcagagatcattgctgctgaagatgatgactttgaccctgagcaggagcaggtgaac
ggccagtgcagctgctttcagagtatcgagctgctcaagactcgccccgctcatcttgca
gctttcctgcaccatgtgatctctcagtttgaccctgcacctctgttctgctacctgtac
gctgacctctacaaacaaaccaactccaaagaaacacggcgcatcttcacggacttcttg
acgttcttcttagaccggggggcaaatttgaaagtcgctgtgcctgaatccatctcctct
gagctcgagcggcggagaccagagctgattcctgaggaattacacaggcaatttatacag
acgatgcaggaaactctccttccggatgtacagagaaacttggaagacttcaggcagaag
cgcagcatgggcttgaccttggctgatgttgagctgtctcgtctagactccgaacagccg
gctctagagagagagagatcatgcgctgaaaacatcctctccaaaatagatgacgttctg
ttgacttcacaacccgcagaagaggagaaatgcaacaccatacagtatgtgatctttatg
tacatgaagcatctgggagttcgggtgaaagagcaacgaaacctggagtccaaacgagtt
cgaattaacttccttccttccaaactaaggaaaagcaaaacagagaaggaaggggaggag
aaactgaaaaagcctcgctttcccatccgggtgcccccacggtggcccagtcgcctcgac
tcagtaccatctgggagggccggagacaacatcaagcatcggcctcagaagcagatgtct
cagccagctttgggcgggtcagagctgatagagggtggacgtctgcggggcagtcagtcg
agtgagggctcagacctcctacacagcccgagtttgatcacctctcctcccttcagcgcc
acttacggcttaccgtcagacccctctggcagggacccggagtttagtatgagtccgtct
gcggtggttccccggctcagtgatggcctgcagtctggagatgtgctagacagcatctac
ccaccttgtgactacatcccatataacatggaccagttagatgaagatggagacagactc
cttgatgtgggcacacctaaactgagtagaagatttgaagagctgcagagcgaagatgat
caggggagtgatgtttactctgatgtagatcctccaaactggcagcagctggtcgggcgt
gatgttttagcaggcctgacgccccacgagatcaagagacaagaagtcattaatgaactg
ttctacacggagcgagcccatgtacgcatgctaaaggtcctagacagtgtcttctaccag
aaactcacccgagacaacatactgccccctgctgacatcaagaacatattcaccaaccta
gaggaaatcatccagctgcatctgaggatagctgatcaaatgacaacgatacgcaagaag
aacgagtcgtccgtcatcgaccacataggagatgagttgctgtcttggttcagtggtgga
gaggaggagaagatcaagcaagcagtgggcactttctgcagtaaccagcccttcgccctg
gagctcatcaaatcccggcagaagaaggaccagcgtttcacctccttcatgcaggaggct
gaaagcaatcgcctgtgtcgacgattacagctaaaggacatcatccctgcagagatgcag
aggttcaccaagtaccccttactgatggacaacattgtcaagtacacagatgagtcagag
gagaaagacaaagtgagacgagcggccgaatgctgtcgacacattctcagccacgtcaac
cagtccgtgaaggagtccgagaataaacagagactggaggactaccagagacggctggac
ctctcttccctcaagcagagcgagaaccccatgatctcggagttcaagaacttggatctc
actaaaagaaagatggttcatgagggccctctgtcctggaagattaacaaagacaaaact
attgagctgtatactttactcctggaagacattctggtgttgctgcagaagcaggacgag
cgttttattctcaggtgtcacagcaagaacctcgcaggaacagctgacacaaaacacata
ttcagtcccatcatcaaactcggcactgtgctggtgcgctcagtggcgacagataacaga
tcgttctttgtgatctccatgtccaaaaacggagctcagatttatgagttgatggcccaa
acagtgtccgagcagagaatgtggcaacggcagattgctcagagggcagaggttatgaac
ggcaaaccccacagcgtcattcctttgcctcagcacgacgttgacagagacagcgtcgag
ctaagcaagttcagcaaaggctctgaacggatctccacaggaagcatccagtccgcagag
aaagacagcgagttttcgcccacggcagccttgcgggattgtgtccccgactccaaccct
ggggaagaagaccaggtcccgagagctggcagggatgcctcgtatctggactcggaactc
ttaaacggcagggacgcagattctctgtcctgttcgtctaaagcagacgaggctcttaaa
accttggcagcgctgaagcaggtgctggtgactcagctgatggctcaggatgagggcgag
cgattgtgccgatcggccggcagtcgtcttctcaggaccacctctctacgcacaccggtg
gagcacagctcaactcgcacccctagtcgagctcaggattacacctctggagatacgggc
ttctacgagtgcccagaggactacgcagcttacctggttctggagggctacggtggccca
ggcgagagcagtacagatgatgatattcaggtccggagaaaggagtcaagtttggcccac
agctgtgctgccgactcgggcatcagtctgaagttctcctcgccctcctcaggcagcacg
tctcgcctcagcagacaggtcctctcacatctgcgctgcctgcaagccaacctcaaccac
ctcaaggagatggaaacaaagtattataatctacttcgccaaaggcctgttgggtcagcc
gcagatccggacgagagcagagataagaaatag
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