Garra rufa (doctor fish): 141287712 Help Entry 141287712         CDS       T11039                                  Symbol obscna Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism grf  Garra rufa (doctor fish) Pathway grf04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:grf00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     141287712 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:grf01001]     141287712 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:grf04131]     141287712 (obscna) Enzymes [BR:grf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      141287712 (obscna) Protein kinases [BR:grf01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    141287712 (obscna) Membrane trafficking [BR:grf04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     141287712 (obscna) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Ig_4 Izumo-Ig SOS1_NGEF_PH Ig_CD22 Ig_6 RhoGEF C2-set_2 PH Kdo IQ Adeno_E3_CR1 Anth_Ig RHG20_PH YfhO Motif Other DBs NCBI-GeneID:  141287712 NCBI-ProteinID:  XP_073675951 LinkDB All DBs Position 15:29303016..29365003 Genome browser AA seq 6631 aa AA seqDB search MALNRIQLVKRLEDVTLCEKEACTFEVVLSHAYIQGQWSKDGVPFKSKPVCRIATQAKKH TLTLTRVTVGDMGVISFKAEGIESSAMLTVTARDIKIVKDLQNASVTERESVTFICEVNW EDVDGKWYKDDSRLRAGDNVKIRCEGKIHSLTYKSVKPEDAGEIRFTAERVSSTATLRVK ELPVHIVKPLRVKIAMYKHRALLECQVSRVNASVKWYRKNYEIVPNRKYQTISEGVYRQL IIDDVGSSDEDTFTCDAVDDRTSCQLFVEEQAISILKGLSSVEVMEPKEARFKVETSIKL ERAPKWTLNGRILCPCPEIRIERQGTSNKLIFTQTDSSMSGTVQFTSGKSKSEAQLTVTE RPLTVNQPISDVEVKENTSVTLSCEYCPSPRVVRWFKGRTPLFASNKYTMKREKNRAEMT IVGVKAADSGEYRCVAGGSETRGRLNVEVRRLKIIRHLEQVEVEEDGTAVFSCELNHESP SVQWLLNDRVLYTNHINKIQNSGKVYSLILKRLAPQESRVTFKTIDVSESAFLRVRERPA VFLRSLEDAAGEERGEILLHCEVSKPSVTPVWRKDGEILTASEKYEILHVGKSLTLVIRK LRKDDGGEYSCDIGCSQTKAKVIVRDLHITIVKRIRTTAVLEGESCSFECVLSHDIIDEA SWILNGQFIVSNGRIIVANKGCKYTMSIQEVMISDAGEVVFTIKELSCRTMLFVKEKPVT VFRDMLNVKATPGEDPELSCEITKPDATIKWLKNGRLIRVSPKFEMTQNNYLVKLIIHNA AIRDSGEYCCEADGIATRARLDVRDLQHAFAKELKDMRAEEKGMVTMECETRRPAATVNW LKGLIELSSGQKYMMKKKDVVLTLTIFNLDKSDSAVYTCDVGTMQSRALLTIHGQKVVIV DELEDKECLEGDTIVFKCRICPSDYEDVKWYLDETLLYTNDLNEIKMMPGGYHTLTFKQL ARKDTGTISFEAGGKRSYASLLVRERRPTITKALEDTEAIEGGSLVLLCKTSKPCHIVWY KDSCLIWNSSKYVVSRSGNEARLTIRDVKDSDAGVYECDAGSVSTKATVTVKVIPAEFTK ALQNQEVKEGESATLMCEYSIPGIQYVWRKGAETLKSSEKYHMKQRRSCISITIHNLKPE DSGNYTCICRDQRTMATLTVNAVPISFIKELKNQETEEGKNVTLRCELSKAGIPVEWLKS EQTLLPGEKYQMRHIVTILELVIRNPVPEDSGMYICVCEDQRTKAIITIRTQPIMFKQKL RNQMAEEGNSIILHCEISKPDIPVQWRKESNLLKSGEKYKIRQRGCMLELKIFNLTQEDS GVYSCMSETAETSANITVSAQPVTFKEKLKNLVAEEGKTITLHCELSKAGVPVEWWNGDE LLRPGEKYKMRERDTSVELIICEAEPEDSGVYRCVCGDQKTKATIKIVGAPATFKQTLKK QEALEGESLTLHCELSKAGVPVEWWRGDKPLLPGSRYQMRLDGKTAELKITNVFPEDAGT YSCVTGGQKTTAEVKVKAHPITFKRELQSQISVEGESAVFICELSKPGAPVEWRKGRVML KSGAKYQMTLEGRLTKLVINNLVEGDAGNYTCKTKDSQSTAELTVQGVPATFKTTLKNQE TQEGNSVTLLCELSKAGVRAEWWKEGEMLKTGEKYQLRQKEATVELLIRKAQPEDSGVYR CVCGDHMTEATIKVNALPITFKQELKNQEGEEGNNVTLRCELSKASPDVKWLKGEEVLKH GEKFQMRQMAAKMELVIRKAVPEDSGVYICECPDQTSKATVKINALPITFKQNLRNQEAV ESNTVALRCELSKPGATVKWWRGEELLQVGEKYQMRTEGRIAELLIKNVDSEDVGSYSCT TGKEKTTAEVKVKALPVTFKRELQNEVTKEGGQAVFICELSKPSAQVDWRKGRVVLKPDD KYEMKQEGTFTKLVIRNVEASDAGNYSCKTKDSESTAELTVKVPPITFKVKLKNQEVEEE NELVLHCELSKAGCPVEWRKGEERLGSGYKYQIREHDVTKELIIMNAMPEDSGVYSCICG EQKTKATVRVFATPVTFKQNLKNQEAPEGGVVILHCELSKAGIPVTWLKGDEELFDGTKY RIKLEGLVAELHIKNVLPMDVGEYSCIVGDQKTTAEVNVRAAASVFFEKELESQEAVEGD SVLFSCLLSNDNAPVTWRKEANQITQGGRYTLHRKGSTQELEIRKLRVQDAGVYTCSVRG KKTTATLRVTELVRIVKGLRDLTVTAGESAHFVCELSHENILDGVWWLGSNVLQENEMNQ MSICGREHHLVLTMTTTEESGVVNFVVGDEKTSARLRVNSKPKVFIEERLKDMTIFEGDS ATLSCVTSDTCTPVTWKRNNVTLLPGEKYEPLKHGKRNVLLIHKVRKEDAGIYMCDTGDM QSSATLTVKERPLFFCLELQNQEAEEGETTFLCCELSQPGVVVEWKKGAILLSPSDKYEM KQDGCEFQLQINDLTSQDSGAYRCCADGIETRASITVKETPLFFREELQNQEAEEGETAF LYCELSKPGVQVQWKKGAMLLKNGQKYEMTQEGNEVQLQIHDLTSHDSGTYRCCAGNIET RANIIVKEQPLFFCEELHNQEAEEGETAFLCCELSKSGVEVQWKKGAIRLRPGNKYEMKQ DGCKVQLQIHDLTREDSGAYKCYSGNLVTTASIIVKEQPLYFIKMLECQEAEEGETALLC CELSKPGAAVQWKKGSVLLKPGRKYKINQNGGELQLQIHELTSQDSGVYTCCVGSLVTSA SLEVKEQPLYFCEELQRQEVKEGETAVLSCELSKPGVEVQWKKGMVLLRPGNKYEMNQDD CKLQLLIHELNSQDSGIYKCCAGSLVTIASIDVKESPIVFEEELQSLEAEEGESATLTCE LSKPGVAVQWKKGTVLLKPGDKYEMKQDGCLQQLQIWDLKYEDSGSYKCCAGSLVTTASL VVKEQPLFFSEELQNQEAEEGKTAILCCELSKPGVSVQWKKGTVLLKPSRKYEIEEDGHQ LQLRINELTAQDSGAYKCCVGSLVTNASLVIKEKPLFFSEELQNQEAEEGKTAILCCELS KPGVSVQWKKGTVLLKPSNKYEIKQDGRQQQLYIHELTTQDSGAYKCCVGSLATTASVVI KEKPLYFSEELQNQESEEGKTAILCCELSKPGVSVQWKKGTVLLKPSNKYEIKQDGSQLQ LYIHELTTQDSAAYKCCVGSLITAASLLVKEKPLFFSEELQNQEAEEGKTAILCCELSKS GVSVQWKKGTVLLKPSKKYEIKENGRQLQLRINELTVQDIGAYKCCAGSLITSASLVVKE KPLFFSKELQNQQEEEGKTAVLHCELSKPGVSVQWTKGTVLLKPSKKYEIKQDGRQLQLR ISDLKAQDSGAYKCCAGNLVTTCSVTVKEQPIFFCKNLQNVEAEEGKTVTLSCELSKPGV AVQWKKGTVLLKPGNKYEMKQDGCVLQLQIRDLKSEDSGSYKCFTGSMVTTASIVVKEHP LFFSEELQNQEAEEGKTVTLCCELSKPGVSVQWNKGAVILKACKKYEIKQDGRKLQLQIN EVTTQDSGTYKCCAGSLVTNCSITVKEQPIFFRKNLQNLEVEEGETALLICELSKPGVAV QWKKGTVLLKPGNTYEMKQNGSELHLQIHDLKCQDSGVYKCCAARMETTASVVVKEAPPR IKEIPQAPPRLKGKNIVEETYSALVHKKPAAVTEASDILEPSEVHFQDLCEKPTDNQKVE RKSLVRQKEKDLSSIMVMNEFSHTMEEPEITSLMTDVPEDQRKKGLDTDSKWVKKISLDQ QDEEISGQVQKKTLSIDSIEQSKEPLRDVPQPPPRSKGKATHPDDSLQDQHSVIEPTVDK KGKEKVSQLHVETKRQTYDLEAKNQDIDIKQTTLKISEYGFNNKEITAKHIESSQEQPCH LEENNQYFKLESKKVQIVDKETKLDEFSLHKPKQKSLDKRPETEKVQSMDEHHGKMTRNI TEKAPSIAITSQKVKEEIITVEKTTANSEESELNLPHTDNEDVKNVKQIVDEHKIKAPKH ITEKVTNIAITNQKPKEEIVFAQKDTTIPVRDVQKELQAGEPKVQVKQVVEEHNGKEPMH VTGKARHIAITSQFKEEIVPAEKATAMSIRDVQREELNLLHIDSGDEKNVNVPKHVKEKA TSITGQKIKEQIIPVERAKKMSLKASQEVEPNLPLMDNKVKQVVLEKGISRGSSTQPDGT MPEQITNVDTDKQMSSKVEQGGAGVEVDFEDEPEMLEAAIKIQAAFKGYKTRKDMRLVFK EVFKNQNVDLGGTAFLECFVEGKISTVRWFKDGVDLKPGKRHKITHNADGRCHLEISRVT NKDAGIYTCEVANKFGAISYNGNVTVGKPQKPSQTIQTAQIPGTENVSEKEVVPTLNTEE ESLRLVYDLPADDTYSKIQEKRKSLISVSSISCHSDYDTAPDVETEYQSRGNKAEKSKTE APTAQTAEEEKRVSVQSPTNTDQLKVKGGDSQGQTPSPKRMHSYKSSANAESLSESDGDD DRRATFDIYVAKSDCQPLGGNKEAFVLKEGQFVEVLDSAHPVRWLVRTKPTKITPSRQGW VSPAYLEKKTREIFSLAHEAETKEPVEKGKIVFTKDEHSLIQSRLIKGLLDGENNFVCEM NFFVEHHLQYLETSSKVPLTILSQKEYIFRNIRDIANFHECCILPKLEMCFSDDDLAQCF VSYALDFEMYLQFITGLPQAEACVSDKNTQHFFKQYANTELAHSDTQVFNVSTYLQRPME RIQTYKNVLKELIRNKAKSGQNCCLLEDAFAVVSSLPWRAENLHHLSMIENYPAPLKGLG EPIRQGHFTVWEEVPEVKISQRGHHRHIFLFKECIVFCKPRRELGTYTEAYIFKNKMKLS DIDVKDTVEGDDRSFGLWHEHRGMVRKIILQARSILFRLSWLKDLRDLQQRSKQPTWTAP CFEQHLTDYPAKLGQTVKLVCKVTGTPKPLIKWYKDGYDVKEDEHHITSEGQLGACYLVL TGLTVADSGQYMCYATNPAGNASTLANIMVDVPPSFTTRLQNTVLVKGQDVQFKCSTQSA PLPSISWFKDGIQLENNRKHQIQSDAQTGILTLTIKKAEEADLGQYQCELQNEVGSAKCK AELCPPASLPVTVSTQKQSQTTPDPEPQSEGWSSSFVKNLFHILFQPGYPESQAGSVEDT HAFEEQDDVERQVQAAQAEGPVEPEEQFYSDTEELLLTEPPAVQVAIEDLTVRPGQSATF SAIITGQPTPEVLWFKDEDEILSNEYTEIVHSSARCSLTLLNTQIEDCGTYTCIASNSEG QASCHAKLIVDIGPDDIEEEREVEFGKRRKLHSVYDVHEEIGRGTFGVVKKVTHKASSEC FAAKFIPLRSSTRTRGFQERDLLSRLAHRRLTCLLDFFATRRTLVLVVELCSTQGLLDHL FLKGSVSEREVQLYIQQVLEGIGYMHSMNILHLDIKTDNILMVSPVREDIKICDFGFCQE IDNSRHQYSKFGTPEFVAPEIVHQEPVTIATDIWSLGVVAYLCLTCHCPFFGENDRATLM KVAEGVLYWDTPEITSRSVEAQDFLHRVLQPDPEMRPSASECLSHEWFQGYYEDEEPEDI NTKNLKAFISRRKWQRSLTCLGSVLTLRPIPELLEAPLRDVSITATRETKEPSSTSLSSG SSSEFDEADAWDFFQQVSQEDEDDLEDEEEYDPYTQVSKTPTVVKRDEEDMLIGEGRIHS GPLVIPMTAPTEPVSLESRDSSPYLHLSEKDEGLDPIPRRSLIKSNFYCSSEQLSPMSAR HMTLRDRIQAKKQERGRKPLRASLSGRLNEPLIEYVEDSPEIEANQRRGSMYSSILKSSS FDCGVSAAHPSLRTQRRSRSLDVYTQRSPASTDPTVQGEDEHDVEESQKPVTDEEQEKPE EVQVRRKLCRRSAFLSKKGPVIVRKVRAQVHEPEEGRQSVSQSSCEDDNQLQITETDTRH LGDEESVEGSQLSLACSLDQASEASSRIGSHEELSHRHHQDETLRSSGKTSPCSLLQDSE DEDMERVLRSLRQDIPQAPPRRRTNSSSSGLNETRNKSDILLRRSSSAVPVQAAKQERDG KELLQRHASAPALQDKPPSGKSSKPGFMKIFRKHSWASHSSPQLEGSEKKQADGASSQPK TPLLTLRKKMRASASSITKLFTRQSSKEDVDKKKGGPIVKNPSIVIPDIMTSTSTVTAAT SPESPQKKSKLFSMKVPMFKKTKESSVKLSRPDVIQLAGGGALVFWKPVPSKELVIYCIQ YSVNGAEWRMLSENVTDSCFTANALPRGPGYIFRVSYKTKTGLAPFSDPSPPAFMATPYE DSHNPLIKMESIGSKVTVPGGLGTEKSYSFLSEINRGRFSVVMQCEDSRSSQILAAKITP YRPEQRQLVLREYQLLRRLNHPRIVQLQSAILTPTCLVLIEELCSGRELLYNLAERNLYS ETQVTDLLEQILSAVDYLHSRRIIHLDLKSDNMLVTGRNVVKIVDLGSAQPFVPGQALNI EHIKEMTDNKGYIVLPKAPEILEGQGVGPETDIWAVGVLAFIMLSADSPFNADINWERDR NIKKGKIQFNRCYPGLSEGAINFMKNTLSNKAWARPTAAECLQNPWIQGDRSLSKHTDSV VCFSTDKLQAYLREREVKRDHVRTKINLPFL NT seq 19896 nt NT seq  +upstreamnt  +downstreamnt atggcattgaatagaattcaattggtgaaaaggctagaagatgtaacgctatgtgagaaa gaagcctgtacgtttgaggtggtcctcagtcatgcgtacatccagggtcaatggagcaag gatggagtcccatttaaatctaagcctgtgtgtcgaattgccacgcaagcgaaaaaacac acactcacacttacgcgagtcacggttggtgacatgggtgtcatcagcttcaaggctgaa gggattgaaagctctgctatgctgacagtcacagccagggatataaagattgttaaggat cttcagaatgccagtgtgactgagagagagagtgtgacatttatctgtgaggtcaactgg gaagatgtggatgggaagtggtacaaagacgacagccggttgagagctggcgacaatgtt aaaataagatgtgagggtaaaatacactccctaacctataaatcagtcaaaccagaagat gctggtgagatcagattcactgctgagagggtctcttcaacagcaacactacgagtcaaa gagcttcccgttcatattgtgaagcccctgagagtgaagattgccatgtacaaacaccgt gctttgctggagtgccaggtctcccgtgtcaatgcttcagttaaatggtacagaaaaaat tatgaaattgtgccaaacaggaagtaccaaactatcagtgaaggtgtgtacagacagctc atcattgatgatgtaggatcctcagatgaagacacttttacctgtgatgctgtcgatgac aggacttcctgccaactgttcgtggaggagcaggccatcagcattttgaaaggactcagt tctgtggaggtcatggagccgaaagaggctcgttttaaagtggaaaccagtattaaatta gagagggctccgaaatggaccctgaatgggcggatactatgtccctgtccagaaatcagg attgagaggcaaggaacctcaaacaaacttattttcactcaaaccgacagtagtatgagt ggaactgtgcagttcacctcagggaagagcaagtcagaagctcagctcacagttacagag cgtcctttgactgtcaatcagcccatttctgatgtggaggtaaaggagaacacgtcagtt acactcagctgtgagtactgtccatcccccagagtggtgcgctggttcaagggtagaacc cccctgtttgcctccaataagtacacaatgaagcgggaaaagaaccgggctgagatgacc atcgtgggtgtgaaagcagcagattcaggagagtatcgctgtgtggctggtggctcagaa acaagaggaagactcaatgtggaagtaaggaggttgaagatcataagacacttagaacaa gtagaggttgaggaggatggaactgccgtgtttagctgtgaactgaatcacgagtcaccc agtgtccagtggctgctcaatgaccgagtcctatacaccaaccacatcaacaaaatccag aattctgggaaagtgtacagtctgattctaaaacgactagctcctcaagagagccgtgta acatttaaaaccattgatgtcagcgagtctgcgttcctcagggtcagagagaggccagct gtgtttctcaggtcactagaggacgctgcaggtgaggaacgtggtgaaatccttcttcac tgtgaggtttctaagccatctgtgacacctgtctggaggaaagatggtgaaattctgact gccagtgagaagtatgagattctccatgttggaaagtcactgactcttgtaattcgcaaa ctgagaaaggatgatggaggggagtacagctgtgatattggctgcagccaaactaaagcg aaagtcatagttcgtgacctgcacattaccattgtcaaacgcatacggacaacagctgtg ctggaaggggaaagctgcagttttgaatgtgtcctgtcccatgatatcattgatgaagca tcatggattttgaatggccagttcattgtgagcaatggacgaatcatagtcgctaacaag ggctgcaaatacacaatgagcattcaggaagttatgatatctgatgccggcgaggttgtt tttaccattaaagagctcagctgcaggactatgctgtttgtcaaagagaagccagtgaca gtgtttagggatatgcttaatgttaaagcaacacctggtgaagatccagagctcagctgt gagatcaccaaacctgacgctacaatcaaatggctgaaaaatggacggctaattcgagtc agcccaaaatttgaaatgacccaaaataattatctggtgaagctcatcatccataatgca gctataagggactcgggggagtactgttgtgaggctgatgggattgctaccagggcaaga ttagatgtcagagacttgcaacatgcgtttgccaaagaactgaaggatatgcgtgcagag gaaaagggtatggtgaccatggagtgtgaaaccaggaggccagccgctaccgtgaactgg ttaaaaggcctgattgagctcagttcaggacaaaagtacatgatgaagaagaaagatgtt gtcctcactctgaccatcttcaatctggacaaaagtgacagtgctgtctacacctgcgac gttgggacaatgcagagcagggctttacttacaatccatggtcaaaaagtggtcattgtt gatgaactagaagataaagagtgtctagaaggagataccatcgtctttaagtgtcggatc tgcccaagtgactacgaggatgtcaaatggtacctggatgagaccttactctacactaat gatcttaatgagatcaagatgatgcctggtggataccacactcttaccttcaaacagctt gcacgtaaagacaccggcaccatctcctttgaggctgggggcaaaagatcatatgcatca ctattagtcagagagaggcgtcccacgataactaaagcattggaagacacagaagcgatt gaaggaggcagtttggtgctcttatgcaagacctcaaagccatgtcatattgtttggtac aaagatagctgtttaatatggaactcctcaaagtatgtagtgagtcgatctggaaatgag gccaggctgaccattcgtgatgtgaaagacagtgacgcaggagtgtacgagtgcgatgca ggatctgtcagcactaaagccactgtgactgttaaagttattcctgctgagtttacaaaa gcacttcagaaccaggaggtcaaagagggagaaagtgcaacgctgatgtgtgaatactct atacctggcatccagtatgtgtggcgcaaaggagccgagacgctaaaatctagtgagaag taccatatgaagcagaggagatcttgcatttctattacaatacacaatctgaagccagaa gattcagggaattacacatgcatttgcagagaccaaagaactatggctactcttacagtc aacgcggttcctatatcatttattaaagagctgaagaaccaagagacagaggagggtaaa aatgtgacattacgctgtgagctttctaaagctggcatcccagtggaatggttgaaaagt gaacaaactctcttgcctggggagaagtatcagatgagacacatagtcaccatactggag ctggtaatcagaaatccagttcccgaggacagtggaatgtacatctgtgtgtgtgaggat caaaggaccaaagccattatcacaatacgaactcagcctatcatgttcaaacagaagtta agaaatcaaatggctgaagagggaaacagtataatcttacactgcgagatctccaaacca gacatccctgttcagtggagaaaggagagcaacctgctcaagtctggagagaagtacaaa atcaggcagagaggctgcatgctagagctgaagatttttaatttgactcaagaggatagc ggagtctatagctgcatgagcgaaactgctgagacatcagccaacatcacagttagcgcg caacctgttacttttaaagaaaagctgaaaaacctggtagccgaggaaggtaagacgatc acattgcactgtgagctttccaaagccggtgtcccagtagaatggtggaatggagacgaa ctgctccggcctggagagaagtataagatgagagaacgagacacatcagttgagctgatc atctgtgaggctgagcctgaggacagtggagtctacagatgtgtctgtggagaccagaag actaaagctacaatcaaaattgtcggtgctcctgctacttttaagcaaacccttaagaaa caagaagctctagaaggggagtctctaactctacactgtgagctctccaaagctggagta cctgtggaatggtggagaggagataaaccgctccttccaggttcacggtaccagatgagg ctggatggaaagactgcagagttgaaaataactaatgttttccctgaggatgctgggaca tacagctgtgtgactggaggccaaaagactacagctgaagtgaaagtcaaagctcatccg attactttcaagcgagagcttcagagtcagatatctgtagaaggtgagagtgcagtattt atctgtgaactttcaaagcctggtgctccagtggagtggaggaaaggtagagtgatgctg aaaagcggagccaaatatcaaatgacgcttgaggggcgattaaccaaactggtgataaat aaccttgttgagggtgatgcgggaaattacacctgcaaaactaaagattcacaatcaaca gccgaattgactgttcaaggagtcccggctacatttaaaacaacactgaagaaccaggaa actcaggaggggaacagtgttactttgctctgtgaactttccaaggctggagtccgagcg gagtggtggaaagaaggagaaatgctgaagactggagaaaaatatcaattgagacagaag gaagcaacagtagagttattaataagaaaggcacaaccagaagacagtggagtgtatcgc tgtgtatgtggagatcacatgactgaagccactatcaaagtcaatgctcttcccatcact ttcaaacaagaacttaagaatcaagaaggtgaagaagggaacaacgtcacattgcgctgt gaactctctaaggccagtcctgatgtgaagtggttgaagggagaggaagtcctgaagcat ggagaaaagttccagatgagacagatggcagctaaaatggagcttgttattagaaaagcc gtacctgaagacagtggagtctacatttgcgaatgccctgatcagacatccaaagctaca gtaaaaatcaatgcactcccaatcactttcaaacaaaacttgagaaatcaagaagcagta gaaagcaacactgttgctttgcgttgtgagctttccaaaccgggagccacagtgaaatgg tggaggggtgaagagctgctccaagttggagaaaaataccagatgaggactgagggacgg attgctgaacttctcatcaagaatgttgactctgaagatgtcgggtcttacagctgcact actggaaaggaaaaaacgacagcggaggtcaaagtcaaggctttacctgtcacttttaaa cgagaacttcaaaacgaagtaaccaaagaaggtgggcaagctgtgtttatctgtgagctc tctaaacccagtgctcaagttgactggagaaaaggaagagttgttctcaagcctgatgac aaatatgaaatgaagcaagagggaacattcacaaaactggtaatacgtaatgttgaagca agtgacgctgggaactattcatgtaaaaccaaggattctgagtctacagctgagctaacc gttaaggttccacctatcacttttaaagtcaagttgaaaaatcaggaagttgaagaagaa aatgaacttgtgttgcactgtgagctctcaaaagctggatgtcctgttgaatggaggaag ggggaagagcgtctcgggtctgggtataaatatcaaatcagagaacatgatgtcacaaag gaactgatcattatgaatgccatgcctgaagacagtggagtctacagctgcatttgtggg gagcagaagaccaaagccacagtccgggtgttcgccacgccagtgacattcaaacaaaac ctgaagaaccaagaggcccctgagggaggtgttgttattctgcattgtgagctgtccaaa gctgggataccagtaacatggttgaaaggggatgaggagctcttcgatggcactaaatac agaatcaagctggagggattggttgcagaattacacattaaaaatgtccttcctatggat gttggggaatacagctgcattgttggagaccagaagactacagctgaagttaatgttagg gctgctgcctctgtgttctttgagaaagaacttgagagtcaagaagcagtggagggggat tctgtcctgtttagttgtttgctctctaacgataatgctccagtgacctggagaaaagag gcaaatcagatcacacaaggtgggcgatataccctccaccgcaaaggttccactcaggag ctcgaaattaggaaactaagagtgcaggatgctggtgtgtacacgtgcagcgtcagaggc aaaaagactaccgcgaccctcagagtgacagagcttgtgaggattgtgaaaggactgcgt gacttgacggttactgcaggcgagagcgcacactttgtgtgtgagctttcgcatgagaac atccttgatggagtttggtggcttggttccaatgtacttcaagagaacgagatgaaccag atgagtatctgtggtcgagaacatcacttggtgctcactatgaccacaactgaagagtca 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tttgattgtggagtgagtgctgcccatccaagcctacgcacccagagaagaagcaggtca ttagatgtatacacacaacgctctccagcttcaactgacccaacagtgcaaggagaggat gagcatgatgtcgaagaaagccagaaacctgtcactgatgaagaacaggaaaaacccgaa gaagtccaggtgagaaggaaactttgcagacgctctgcgtttttgtcgaagaagggccca gtaattgtgagaaaggtgagagcgcaagttcatgagcccgaagaaggacgtcagtcagtg tcacaaagttcttgtgaagatgacaaccaattgcagatcacagaaacagatacaagacat ttaggtgatgaggaaagcgttgagggctcacagctttcactagcatgctctcttgaccaa gcttcagaggcctctagcaggataggctcacatgaagagctttcccacagacaccaccaa gatgagaccttgagatcctctggaaaaacatctccatgctctttactacaggactccgag gatgaagacatggagagggtcctgcgttctcttcgccaagacatcccgcaagccccacca agacggcgcaccaacagttcaagctctggactaaatgagacgcgtaataaaagtgacatc cttctgagaagaagctcctctgcggttcctgtccaggctgcaaagcaagaacgagacggt aaagagttgcttcaaagacatgcctcagccccagctcttcaagacaaaccccctagtggg aaatcttccaagcctggattcatgaagatcttccggaagcactcgtgggctagccattct tctcctcaactggaaggctcggagaagaaacaagcagatggagcatcctcacaacccaag acccctcttctaaccctgaggaagaagatgcgagcttcagcctcaagcattacaaaactg 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